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Self-folding devices and materials for biomedical applications
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SUMMARY Since the native cellular environment is three dimensional (3D), there is a need to extend planar, micro and nanostructured biomedical devices to the third dimension. Self-folding methods can extend the precision of planar lithographic patterning into the third dimension and create reconfigurable structures that fold or un-fold in response to specific environmental cues. Here, we review the use of hinge-based self-folding methods in the creation of functional 3D biomedical devices including precisely patterned nano to centimeter scale polyhedral containers, scaffolds for cell culture, and reconfigurable surgical tools such as grippers that respond autonomously to specific chemicals.
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Metadata
- Authors
- Randall, C. L., Gultepe, E., & Gracias, D. H.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2012-03
- Volume
- 30
- Issue
- 3
- Pages
- 138-146
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2053207301
- Cited by
- 269
- References
- 67
- FWCI
- 3.92
- Type
- journal article
- Language
- en
- Open access
- green
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