Campylobacter flagella: not just for motility

Guerry, Patricia

doi:10.1016/j.tim.2007.09.006

Cited by 341Salmonella and Campylobacter epidemiologyHelicobacter pylori-related gastroenterology studiesBacterial Genetics and Biotechnology

Campylobacter flagella: not just for motility

Guerry, Patricia·2007·Trends in Microbiology

DOI 10.1016/j.tim.2007.09.006

Open this paper in CoChat — free account

Abstract

Campylobacter jejuni and Campylobacter coli are among the major causes of diarrheal disease worldwide. The motility imparted by the polar flagella of these pathogens is required for colonization of the mucus lining of the gastrointestinal tract. However, recent studies have revealed a more complex role for flagella in Campylobacter pathogenesis that includes the ability to secrete non-flagellar proteins that modulate virulence and the co-regulation of secreted and non-secreted virulence factors with the flagella regulon. Campylobacter flagellins are heavily glycosylated and changes in glycan composition affect autoagglutination and microcolony formation on intestinal epithelial cells; these traits are associated with disease in an animal model. Here, these recent advances in our understanding of the multifaceted role of flagella in Campylobacter virulence are summarized.

Integrity signals

Registry

Crossref · 10.1016/j.tim.2007.09.006

Cites

77 of 77 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

In some cases, carbohydrates, particularly exopolysaccharides, can act as autoagglutinins.
“In some cases, also carbohydrates, particularly exopolysaccharides, can act as autoagglutinins.”
From Bacterial autoaggregation (2018) · cites this paper as [17]
In Campylobacter jejuni, the autoaggregative phenotype is dependent on glycosylation of flagella.
“A different example of carbohydrate-mediated autoaggregation is found in Campylobacter jejuni, where the autoaggregative phenotype is dependent on glycosylation of flagella [17].”
From Bacterial autoaggregation (2018) · cites this paper as [17]

Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants
Hueck, C. J. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.2.379-433.1998 · Cited by 2,384 · see citing works
The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences
Parkhill, J., Wren, B. W., Mungall, K., Ketley, J. M., Churcher, C. M., Basham, D., Chillingworth, T., Davies, R. M., Feltwell, T., Holroyd, S. A., et al. (2000) · Nature · doi:10.1038/35001088 · Cited by 1,966 · see citing works
Type III Secretion Machines: Bacterial Devices for Protein Delivery into Host Cells
Galán, J. E., & Collmer, A. (1999) · Science · doi:10.1126/science.284.5418.1322 · Cited by 1,323 · see citing works
Experimental Campylobacter jejuni Infection in Humans
Black, R. E., Levine, M. M., Clements, M. L., Hughes, T. P., & Blaser, M. J. (1988) · The Journal of Infectious Diseases · doi:10.1093/infdis/157.3.472 · Cited by 1,063 · see citing works
Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations
Friedman, C. R., Neimann, J., Wegener, H. C., & Tauxe, R. V. (2000) · Medical Entomology and Zoology · Cited by 902 · see citing works
Experimental Campylobacter Jejuni Infection in Humans
Black, R. E., Levine, M. M., Clements, M. L., Hughes, T. P., & Blaser, M. J. (1988) · doi:10.21236/ada265410 · Cited by 869 · see citing works
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
Smith, K. D., Andersen‐Nissen, E., Hayashi, F., Strobe, K. L., Bergman, M. A., Barrett, S. L. R., Cookson, B. T., & Aderem, A. A. (2003) · Nature Immunology · doi:10.1038/ni1011 · Cited by 808 · see citing works
Evasion of Toll-like receptor 5 by flagellated bacteria
Andersen‐Nissen, E., Smith, K. D., Strobe, K. L., Barrett, S. L. R., Cookson, B. T., Logan, S. M., & Aderem, A. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502040102 · Cited by 657 · see citing works
Major Structural Differences and Novel Potential Virulence Mechanisms from the Genomes of Multiple Campylobacter Species
Fouts, D. E., Mongodin, E. F., Mandrell, R. E., Miller, W. G., Rasko, D. A., Ravel, J., Brinkac, L. M., DeBoy, R. T., Parker, C. T., Daugherty, S. C., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0030015 · Cited by 539 · see citing works
Virulence Mechanisms of Bacterial Pathogens
Kudva, I. T. (2016) · ASM Press eBooks · doi:10.1128/9781555819286 · Cited by 408 · see citing works
Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract
Hendrixson, D. R., & DiRita, V. J. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.03988.x · Cited by 401 · see citing works
Identification of the Carbohydrate Moieties and Glycosylation Motifs in Campylobacter jejuni Flagellin
Thibault, P., Logan, S. M., Kelly, J. F., Brisson, J., Ewing, C. P., Trevor J. TRUST, & Guerry, P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104529200 · Cited by 370 · see citing works
Secretion of Virulence Proteins from Campylobacter jejuni Is Dependent on a Functional Flagellar Export Apparatus
Konkel, M. E., Klena, J. D., Rivera‐Amill, V., Monteville, M. R., Biswas, D., Raphael, B. H., & Mickelson, J. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.11.3296-3303.2004 · Cited by 365 · see citing works
Unique Features of a Highly Pathogenic Campylobacter jejuni Strain
Hofreuter, D., Tsai, J., Watson, R. O., Novik, V., Altman, B., Benitez, M., Clark, C., Perbost, C. S., Jarvie, T. P., Du, L., et al. (2006) · Infection and Immunity · doi:10.1128/iai.00210-06 · Cited by 308 · see citing works
Structural, genetic and functional characterization of the flagellin glycosylation process in Helicobacter pylori
Schirm, M., Soo, E. C., Aubry, A. J., Austin, J. W., Thibault, P., & Logan, S. M. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03527.x · Cited by 295 · see citing works
Inactivation of Campylobacter jejuni flagellin genes by homologous recombination demonstrates that flaA but not flaB is required for invasion.
Wassenaar, T. M., Bleumink‐Pluym, N. M. C., & van der Zeijst, B. A. M. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07736.x · Cited by 292 · see citing works
Unusual microtubule-dependent endocytosis mechanisms triggered by Campylobacter jejuni and Citrobacter freundii.
Oelschlaeger, T. A., Guerry, P., & Kopecko, D. J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.14.6884 · Cited by 288 · see citing works
A phase‐variable capsule is involved in virulence of Campylobacter jejuni 81‐176
Bacon, D., Szymanski, C. M., Burr, D. H., Silver, R. P., Alm, R. A., & Guerry, P. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02431.x · Cited by 288 · see citing works
Bacterial secreted proteins are required for the internalization of Campylobacter jejuni into cultured mammalian cells
Konkel, M. E., Kim, B. J., Rivera‐Amill, V., & Garvis, S. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01376.x · Cited by 284 · see citing works
Proteomic Analysis ofCampylobacter jejuni11168 Biofilms Reveals a Role for the Motility Complex in Biofilm Formation
Kalmokoff, M. L., Lanthier, P. H., Tremblay, T., Foss, M., Lau, P. C. Y., Sanders, G., Austin, J. W., Kelly, J. F., & Szymanski, C. M. (2006) · Journal of Bacteriology · doi:10.1128/jb.01975-05 · Cited by 277 · see citing works
Changes in flagellin glycosylation affect Campylobacter autoagglutination and virulence
Guerry, P., Ewing, C. P., Schirm, M., Lorenzo, M., Kelly, J., Pattarini, D., Majam, G., Thibault, P., & Logan, S. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05100.x · Cited by 265 · see citing works
Biofilm formation in Campylobacter jejuni
Joshua, G. W. P., Guthrie-Irons, C., Karlyshev, A. V., & Wren, B. W. (2006) · Microbiology · doi:10.1099/mic.0.28358-0 · Cited by 260 · see citing works
Characterization of Campylobacter jejuni Biofilms under Defined Growth Conditions
Reeser, R. J., Medler, R. T., Billington, S. J., Jost, B. H., & Joens, L. A. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00740-06 · Cited by 230 · see citing works
Role of Campylobacter jejuni flagella as colonization factors for three-day-old chicks: analysis with flagellar mutants
Nachamkin, I., Yang, X. H., & Stern, N. J. (1993) · Applied and Environmental Microbiology · doi:10.1128/aem.59.5.1269-1273.1993 · Cited by 221 · see citing works
Flagellar glycosylation – a new component of the motility repertoire?
Logan, S. M. (2006) · Microbiology · doi:10.1099/mic.0.28735-0 · Cited by 221 · see citing works
Phase Variation ofCampylobacter jejuni81-176 Lipooligosaccharide Affects Ganglioside Mimicry and Invasiveness In Vitro
Guerry, P., Szymanski, C. M., Prendergast, M. M., Hickey, T. E., Ewing, C. P., Pattarini, D. L., & Moran, A. P. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.787-793.2002 · Cited by 218 · see citing works
Motility as an Intestinal Colonization Factor for Campylobacter jejuni
Morooka, T., UMEDA, A., & Amako, K. (1985) · Microbiology · doi:10.1099/00221287-131-8-1973 · Cited by 212 · see citing works
Characterization of Monospecies Biofilm Formation by Helicobacter pylori
Cole, S. P., Harwood, J. I., Lee, R., She, R., & Guiney, D. G. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.10.3124-3132.2004 · Cited by 212 · see citing works
Epidemiology of SporadicCampylobacterInfection in the United States and Declining Trend in Incidence, FoodNet 1996–1999
Samuel, M. C., Vugia, D. J., Shallow, S., Marcus, R., Segler, S. D., McGivern, T., Kassenborg, H. D., Reilly, K. F., Kennedy, M., Angulo, F. J., et al. (2004) · Clinical Infectious Diseases · doi:10.1086/381583 · Cited by 210 · see citing works
Genome-wide Expression Analyses of Campylobacter jejuni NCTC11168 Reveals Coordinate Regulation of Motility and Virulence by flhA
Carrillo, C. D., Taboada, E. N., Nash, J. H. E., Lanthier, P. H., Kelly, J. F., Lau, P. C. Y., Verhulp, R., Mykytczuk, O., Sy, J., Findlay, W. A., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401134200 · Cited by 209 · see citing works
Pseudaminic acid, the major modification on Campylobacter flagellin, is synthesized via the Cj1293 gene
Goon, S., Kelly, J. F., Logan, S. M., Ewing, C. P., & Guerry, P. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03725.x · Cited by 202 · see citing works
Mucus colonization as a determinant of pathogenicity in intestinal infection by Campylobacter jejuni: a mouse cecal model
Lee, A., O’Rourke, J., Barrington, P. J., & Trevor J. TRUST (1986) · Infection and Immunity · doi:10.1128/iai.51.2.536-546.1986 · Cited by 200 · see citing works
Role of two flagellin genes in Campylobacter motility
Guerry, P., Alm, R. A., Power, M. E., Logan, S. M., & Trevor J. TRUST (1991) · Journal of Bacteriology · doi:10.1128/jb.173.15.4757-4764.1991 · Cited by 200 · see citing works
The Genome-Sequenced Variant of Campylobacter jejuni NCTC 11168 and the Original Clonal Clinical Isolate Differ Markedly in Colonization, Gene Expression, and Virulence-Associated Phenotypes
Gaynor, E. C., Cawthraw, S. A., Manning, G., MacKichan, J. K., Falkow, S., & Newell, D. G. (2003) · Journal of Bacteriology · doi:10.1128/jb.186.2.503-517.2004 · Cited by 189 · see citing works
Structural and functional analysis of two Campylobacter jejuni flagellin genes.
Nuijten, P. J. M., van Asten, F. J. A. M., Gaastra, W., & van der Zeijst, B. A. M. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)38234-6 · Cited by 186 · see citing works
Transcription of σ54‐dependent but not σ28‐dependent flagellar genes in Campylobacter jejuni is associated with formation of the flagellar secretory apparatus
Hendrixson, D. R., & DiRita, V. J. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03731.x · Cited by 181 · see citing works
CheY‐mediated modulation of Campylobacter jejuni virulence
Yao, R., Burr, D. H., & Guerry, P. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.2861650.x · Cited by 179 · see citing works
INCIDENCE, ETIOLOGY, AND IMPACT OF DIARRHEA AMONG LONG-TERM TRAVELERS (US MILITARY AND SIMILAR POPULATIONS): A SYSTEMATIC REVIEW
Riddle, M. S., Sanders, J. W., Putnam, S. D., & Tribble, D. R. (2006) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2006.74.891 · Cited by 175 · see citing works
Campylobacter jejuni motility and invasion of Caco-2 cells
Szymanski, C. M., King, M., Haardt, M., & Armstrong, G. D. (1995) · Infection and Immunity · doi:10.1128/iai.63.11.4295-4300.1995 · Cited by 171 · see citing works
Pathogenesis of enteric Campylobacter infection
van Vliet, A. H. M., & Ketley, J. M. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01353.x · Cited by 161 · see citing works
Virulence plasmid-associated autoagglutination in Yersinia spp
Skurnik, M., Bölin, I., Heikkinen, H., Piha, S., & Wolf-Watz, H. (1984) · Journal of Bacteriology · doi:10.1128/jb.158.3.1033-1036.1984 · Cited by 160 · see citing works
Secretion of the Virulence‐AssociatedCampylobacterInvasion Antigens fromCampylobacter jejuniRequires a Stimulatory Signal
Rivera‐Amill, V., Kim, B. J., Seshu, J., & Konkel, M. E. (2001) · The Journal of Infectious Diseases · doi:10.1086/320704 · Cited by 160 · see citing works
Functional Characterization of Dehydratase/Aminotransferase Pairs from Helicobacter and Campylobacter
Schoenhofen, I. C., McNally, D. J., VINOGRADOV, E. V., Whitfield, D. M., Young, N. M., Dick, S., Wakarchuk, W. W., Brisson, J., & Logan, S. M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m511021200 · Cited by 156 · see citing works
The TibA Adhesin/Invasin from EnterotoxigenicEscherichia coliIs Self Recognizing and Induces Bacterial Aggregation and Biofilm Formation
Sherlock, O., Vejborg, R. M., & Klemm, P. (2005) · Infection and Immunity · doi:10.1128/iai.73.4.1954-1963.2005 · Cited by 149 · see citing works
Structural heterogeneity of carbohydrate modifications affects serospecificity of Campylobacter flagellins
Logan, S. M., Kelly, J. F., Thibault, P., Ewing, C. P., & Guerry, P. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03185.x · Cited by 146 · see citing works
FlaC, a protein of Campylobacter jejuni TGH9011 (ATCC43431) secreted through the flagellar apparatus, binds epithelial cells and influences cell invasion
Song, Y. C., Jin, S., Louie, H., Ng, D., Lau, R., Zhang, Y., Weerasekera, R., Rashid, S. A., Ward, L. A., Der, S. D., et al. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04175.x · Cited by 145 · see citing works
Identification of Motility and Autoagglutination Campylobacter jejuni Mutants by Random Transposon Mutagenesis
Golden, N. J., & Acheson, D. W. K. (2002) · Infection and Immunity · doi:10.1128/iai.70.4.1761-1771.2002 · Cited by 144 · see citing works
Reversible expression of flagella in Campylobacter jejuni
Caldwell, M. B., Guerry, P., Lee, E. C., Burans, J. P., & Walker, R. I. (1985) · Infection and Immunity · doi:10.1128/iai.50.3.941-943.1985 · Cited by 134 · see citing works
Campylobacter jejuniColonization of Mice with Limited Enteric Flora
Chang, C. C., & Miller, J. F. (2006) · Infection and Immunity · doi:10.1128/iai.01094-05 · Cited by 132 · see citing works
Identification of Unusual Bacterial Glycosylation by Tandem Mass Spectrometry Analyses of Intact Proteins
Schirm, M., Schoenhofen, I. C., Logan, S. M., Waldron, K. C., & Thibault, P. (2005) · Analytical Chemistry · doi:10.1021/ac051316y · Cited by 128 · see citing works
Motility of Campylobacter jejuni in a Viscous Environment: Comparison with Conventional Rod-shaped Bacteria
Ferrero, R. L., & Lee, A. (1988) · Microbiology · doi:10.1099/00221287-134-1-53 · Cited by 123 · see citing works
A phase‐variable mechanism controlling the Campylobacter jejuni FlgR response regulator influences commensalism
Hendrixson, D. R. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05336.x · Cited by 119 · see citing works
Functional Characterization of the Flagellar Glycosylation Locus in Campylobacter jejuni 81–176 Using a Focused Metabolomics Approach
McNally, D. J., Hui, J. P. M., Aubry, A. J., Mui, K., Guerry, P., Brisson, J., Logan, S. M., & Soo, E. C. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603777200 · Cited by 116 · see citing works
Targeted Metabolomics Analysis of Campylobacter coli VC167 Reveals Legionaminic Acid Derivatives as Novel Flagellar Glycans
McNally, D. J., Aubry, A. J., Hui, J. P. M., Khieu, N. H., Whitfield, D. M., Ewing, C. P., Guerry, P., Brisson, J., Logan, S. M., & Soo, E. C. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611027200 · Cited by 112 · see citing works
Single amino acid substitutions in the N‐terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance
Chiang, S. L., Taylor, R. K., Koomey, M., & Mekalanos, J. J. (1995) · Molecular Microbiology · doi:10.1111/j.1365-2958.1995.mmi_17061133.x · Cited by 111 · see citing works
Identification and characterization of genes required for post‐translational modification of Campylobacter coli VC167 flagellin
Guerry, P., Doig, P. C., Alm, R. A., Burr, D. H., Kinsella, N. M., & Trevor J. TRUST (1996) · Molecular Microbiology · doi:10.1046/j.1365-2958.1996.369895.x · Cited by 107 · see citing works
Heterogeneity of a Campylobacter jejuni Protein That Is Secreted through the Flagellar Filament
Poly, F., Ewing, C. P., Goon, S., Hickey, T. E., Rockabrand, D., Majam, G., Lee, L., Phan, J., Savarino, N. J., & Guerry, P. (2007) · Infection and Immunity · doi:10.1128/iai.00159-07 · Cited by 104 · see citing works
Detection and Characterization of Autoagglutination Activity by Campylobacter jejuni
Misawa, N., & Blaser, M. J. (2000) · Infection and Immunity · doi:10.1128/iai.68.11.6168-6175.2000 · Cited by 104 · see citing works
Significance of flagella in colonization resistance of rabbits immunized with Campylobacter spp
Pavlovskis, O. R., Rollins, D. M., Haberberger, R. L., Green, A. E., Habash, L., Strocko, S., & Walker, R. I. (1991) · Infection and Immunity · doi:10.1128/iai.59.7.2259-2264.1991 · Cited by 102 · see citing works
Virulent aggregates of Streptococcus pyogenes are generated by homophilic protein–protein interactions
Frick, I.-M., Mörgelin, M., & Björck, L. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.02084.x · Cited by 100 · see citing works
Isolation of nonchemotactic mutants of Campylobacter jejuni and their colonization of the mouse intestinal tract
Takata, T., Fujimoto, S., & Amako, K. (1992) · Infection and Immunity · doi:10.1128/iai.60.9.3596-3600.1992 · Cited by 90 · see citing works
Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori
Schoenhofen, I. C., Lunin, V. V., Julien, J., Li, Y., Ajamian, E., Matte, A., Cygler, M., Brisson, J., Aubry, A. J., Logan, S. M., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512987200 · Cited by 88 · see citing works
Flipping the switch: bringing order to flagellar assembly
Ferris, H. U., & Minamino, T. (2006) · Trends in Microbiology · doi:10.1016/j.tim.2006.10.006 · Cited by 84 · see citing works
Effects of Quorum Sensing on flaA Transcription and Autoagglutination in Campylobacter jejuni
Jeon, B., Itoh, K., Misawa, N., & Ryu, S. (2003) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2003.tb03449.x · Cited by 79 · see citing works
Bundle-Forming Pili and EspA Are Involved in Biofilm Formation by EnteropathogenicEscherichia coli
Moreira, C. G., Palmer, K., Whiteley, M., Sircili, M. P., Trabulsi, L. R., Castro, A. F. P., & Sperandio, V. (2006) · Journal of Bacteriology · doi:10.1128/jb.00177-06 · Cited by 77 · see citing works
CLINIC-BASED SURVEILLANCE FOR BACTERIAL- AND ROTAVIRUS-ASSOCIATED DIARRHEA IN EGYPTIAN CHILDREN
Wierzba, T. F., Abdel-Messih, I. A., Abu‐Elyazeed, R., Putnam, S. D., KAMAL, K. A., Rozmajzl, P. J., Ahmed, S. F., Fatah, A., ZABEDY, K., Shaheen, H. I., et al. (2006) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2006.74.148 · Cited by 75 · see citing works
Genome Sequence of a Clinical Isolate of Campylobacter jejuni from Thailand
Poly, F., Read, T. D., Tribble, D. R., Baqar, S., Lorenzo, M., & Guerry, P. (2007) · Infection and Immunity · doi:10.1128/iai.00050-07 · Cited by 74 · see citing works
Localized Reversible Frameshift Mutation in the flhA Gene Confers Phase Variability to Flagellin Gene Expression in Campylobacter coli
Park, S. F., Purdy, D., & Leach, S. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.1.207-210.2000 · Cited by 66 · see citing works
Analysis of the Roles of FlgP and FlgQ in Flagellar Motility of Campylobacter jejuni
Sommerlad, S. M., & Hendrixson, D. R. (2006) · Journal of Bacteriology · doi:10.1128/jb.01199-06 · Cited by 65 · see citing works
Survival of Campylobacter jejuni in potable water biofilms: a comparative study with different detection methods
Lehtola, M. J., Pitkänen, T., Miebach, L., & Miettinen, I. T. (2006) · Water Science & Technology · doi:10.2166/wst.2006.448 · Cited by 53 · see citing works
Temperature-Regulated Microcolony Formation byBurkholderia pseudomalleiRequirespilAand Enhances Association with Cultured Human Cells
Boddey, J. A., Flegg, C. P., Day, C. J., Beacham, I. R., & Peak, I. R. (2006) · Infection and Immunity · doi:10.1128/iai.00569-06 · Cited by 51 · see citing works
A σ 28 -Regulated Nonflagella Gene Contributes to Virulence of Campylobacter jejuni 81-176
Goon, S., Ewing, C. P., Lorenzo, M., Pattarini, D. L., Majam, G., & Guerry, P. (2005) · Infection and Immunity · doi:10.1128/iai.74.1.769-772.2006 · Cited by 50 · see citing works
Structural and antigenic characteristics of Campylobacter coli FlaA flagellin
Power, M. E., Guerry, P., McCubbin, W. D., Kay, C. M., & Trevor J. TRUST (1994) · Journal of Bacteriology · doi:10.1128/jb.176.11.3303-3313.1994 · Cited by 49 · see citing works
Virulence Mechanisms of Bacterial Pathogens
(2007) · Wiley eBooks · doi:10.1128/9781555815851 · Cited by 44 · see citing works
The flgE gene of Campylobacter coli is under the control of the alternative sigma factor sigma54
Kinsella, N. M., Guerry, P., Cooney, J. C., & Trevor J. TRUST (1997) · Journal of Bacteriology · doi:10.1128/jb.179.15.4647-4653.1997 · Cited by 38 · see citing works
PseG of Pseudaminic Acid Biosynthesis
Liu, F., & Tanner, M. E. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602972200 · Cited by 34 · see citing works
The Role of Flagella inCampylobacterVirulence
Guerry, P. (2007) · doi:10.1128/9781555815851.ch13 · Cited by 3 · see citing works

Flagged first, then by citations

Sorted by citations

Immune adaptations that maintain homeostasis with the intestinal microbiota
Hooper, L. V., & Macpherson, A. J. (2010) · Nature reviews. Immunology · doi:10.1038/nri2710 · Cited by 1,455 · see citing works
How bacterial pathogens colonize their hosts and invade deeper tissues
Ribet, D., & Cossart, P. (2015) · Microbes and Infection · doi:10.1016/j.micinf.2015.01.004 · Cited by 747 · see citing works
Campylobacter spp. as a Foodborne Pathogen: A Review
Silva, J. G. L., Leite, D., Fernandes, M., Mena, C., Gibbs, P., & Teixeira, P. (2011) · Front. Microbio. · doi:10.3389/fmicb.2011.00200 · Cited by 632 · see citing works
Protein glycosylation in bacteria: sweeter than ever
Nothaft, H., & Szymanski, C. M. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2383 · Cited by 531 · see citing works
Taxonomy, Epidemiology, and Clinical Relevance of the Genus Arcobacter
Collado, L., & Figueras, M. J. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00034-10 · Cited by 478 · see citing works
Bacterial autoaggregation
Trunk, T., Bacterial Cell Surface Group, S. F. G. A. E. B., S. Khalil, H., & C. Leo, J. (2018) · AIMS Microbiology · doi:10.3934/microbiol.2018.1.140 · Cited by 444 · see citing works
“A different example of carbohydrate-mediated autoaggregation is found in Campylobacter jejuni, where the autoaggregative phenotype is dependent on glycosylation of flagella [17].”
Background
The flagellum in bacterial pathogens: For motility and a whole lot more
Chaban, B. L., Hughes, V., & Beeby, M. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.10.032 · Cited by 410 · see citing works
Campylobacter virulence and survival factors
Bolton, D. (2014) · Food Microbiology · doi:10.1016/j.fm.2014.11.017 · Cited by 372 · see citing works
The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems
Abby, S. S., & Rocha, E. P. C. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002983 · Cited by 308 · see citing works
Microbial adhesins to gastrointestinal mucus
Juge, N. (2011) · Trends in Microbiology · doi:10.1016/j.tim.2011.10.001 · Cited by 302 · see citing works
Microbial interspecies interactions: recent findings in syntrophic consortia
Kouzuma, A., Kato, S., & Watanabe, K. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00477 · Cited by 258 · see citing works
Do symbiotic bacteria subvert host immunity?
Hooper, L. V. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2114 · Cited by 256 · see citing works
Investigation of the human pathogen Acinetobacter baumannii under iron limiting conditions
Eijkelkamp, B. A., Hassan, K. A., Paulsen, I. T., & Brown, M. H. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-126 · Cited by 220 · see citing works
Modulation of immune homeostasis by commensal bacteria
Ivanov, I. I., & Littman, D. R. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2010.12.003 · Cited by 183 · see citing works
The Genome of Th17 Cell-Inducing Segmented Filamentous Bacteria Reveals Extensive Auxotrophy and Adaptations to the Intestinal Environment
Sczesnak, A., Segata, N., Qin, X., Gevers, D., Petrosino, J. F., Huttenhower, C., Littman, D. R., & Ivanov, I. I. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.08.005 · Cited by 184 · see citing works
Lack of a type-2 glycosyltransferase in the fish pathogen Flavobacterium psychrophilum determines pleiotropic changes and loss of virulence
Pérez-Pascual, D., Gómez, E., & Guijarro, J. A. (2015) · Veterinary Research · doi:10.1186/s13567-014-0124-5 · Cited by 182 · see citing works
Host Epithelial Cell Invasion by Campylobacter jejuni: Trigger or Zipper Mechanism?
Cróinı́n, T. Ó., & Backert, S. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00025 · Cited by 149 · see citing works
Comparative bioinformatics analysis of the mammalian and bacterial glycomes
Adibekian, A., Stallforth, P., Hecht, M.-L., Werz, D. B., Gagneux, P., & Seeberger, P. H. (2010) · Chemical Science · doi:10.1039/c0sc00322k · Cited by 149 · see citing works
Emerging facets of prokaryotic glycosylation
Schäffer, C., & Messner, P. (2016) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuw036 · Cited by 141 · see citing works
Campylobacter: from microbiology to prevention.
Facciolà, A., Riso, R., Avventuroso, E., Visalli, G., Delia, S. A., & Laganà, P. (2017) · Journal of preventive medicine and hygiene · Cited by 134 · see citing works
Induction of Intestinal Th17 Cells by Flagellins From Segmented Filamentous Bacteria
Wang, Y., Yin, Y., Chen, X., Zhao, Y., Wu, Y., Li, Y., Wang, X., Chen, H., & Xiang, C. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02750 · Cited by 130 · see citing works
Campylobacter sugars sticking out
Guerry, P., & Szymanski, C. M. (2008) · Trends in Microbiology · doi:10.1016/j.tim.2008.07.002 · Cited by 128 · see citing works
Transmigration route of Campylobacter jejuni across polarized intestinal epithelial cells: paracellular, transcellular or both?
Backert, S., Boehm, M., Weßler, S., & Tegtmeyer, N. (2013) · Cell Communication and Signaling · doi:10.1186/1478-811x-11-72 · Cited by 115 · see citing works
Sugar coating: bacterial protein glycosylation and host–microbe interactions
Tan, F. Y. Y., Tang, C. M., & Exley, R. M. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.03.016 · Cited by 103 · see citing works
Flagella-Mediated Adhesion and Extracellular DNA Release Contribute to Biofilm Formation and Stress Tolerance of Campylobacter jejuni
Svensson, S. L., Pryjma, M., & Gaynor, E. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106063 · Cited by 111 · see citing works
The Campylobacter jejuni CiaC virulence protein is secreted from the flagellum and delivered to the cytosol of host cells
Neal‐McKinney, J. M., & Konkel, M. E. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00031 · Cited by 108 · see citing works
Identification of Campylobacter jejuni Genes Involved in Its Interaction with Epithelial Cells
Novik, V., Hofreuter, D., & Galán, J. E. (2010) · Infection and Immunity · doi:10.1128/iai.00109-10 · Cited by 107 · see citing works
A link between the assembly of flagella and lipooligosaccharide of the Gram-negative bacterium Campylobacter jejuni
Cullen, T. W., & Trent, M. S. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0913451107 · Cited by 107 · see citing works
Ecological and Evolutionary Interactions in Syntrophic Methanogenic Consortia
Kato, S., & Watanabe, K. (2010) · Microbes and Environments · doi:10.1264/jsme2.me10122 · Cited by 104 · see citing works
Divergence of Quaternary Structures Among Bacterial Flagellar Filaments
Galkin, V. E., Yu, X., Bielnicki, J., Heuser, J., Ewing, C. P., Guerry, P., & Egelman, E. H. (2008) · Science · doi:10.1126/science.1155307 · Cited by 108 · see citing works
Campylobacter sp.: Pathogenicity factors and prevention methods—new molecular targets for innovative antivirulence drugs?
Kreling, V., Falcone, F. H., Kehrenberg, C., & Hensel, A. (2020) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-020-10974-5 · Cited by 102 · see citing works
Sense and sensibility: flagellum-mediated gene regulation
Anderson, J. K., Smith, T. G., & Hoover, T. R. (2009) · Trends in Microbiology · doi:10.1016/j.tim.2009.11.001 · Cited by 101 · see citing works
A tolerogenic mucosal immune response leads to persistent Campylobacter jejuni colonization in the chicken gut
Hermans, D., Pasmans, F., Heyndrickx, M., Immerseel, F. V., Martel, A., Deun, K. V., & Haesebrouck, F. (2011) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2011.615298 · Cited by 98 · see citing works
Metabolite and transcriptome analysis of Campylobacter jejuni in vitro growth reveals a stationary-phase physiological switch
Wright, J. A., Grant, A. J., Hurd, D., Harrison, M., Guccione, E. J., Kelly, D. J., & Maskell, D. J. (2008) · Microbiology · doi:10.1099/mic.0.021790-0 · Cited by 97 · see citing works
Survival mechanisms and culturability of Campylobacter jejuni under stress conditions
Jackson, D. N., Davis, B., Tirado, S. M., Duggal, M., van Frankenhuyzen, J. K., Deaville, D., Wijesinghe, M. A. K., Tessaro, M., & Trevors, J. T. (2009) · Antonie van Leeuwenhoek · doi:10.1007/s10482-009-9378-8 · Cited by 92 · see citing works
Major Host Factors Involved in Epithelial Cell Invasion of Campylobacter jejuni: Role of Fibronectin, Integrin Beta1, FAK, Tiam-1, and DOCK180 in Activating Rho GTPase Rac1
Boehm, M., Krause-Gruszczynska, M., Rohde, M., Tegtmeyer, N., Takahashi, S., Oyarzábal, O. A., & Backert, S. (2011) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2011.00017 · Cited by 90 · see citing works
Campylobacter in the Food Chain
García-Sánchez, L., Melero, B., & Rovira, J. (2018) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2018.04.005 · Cited by 87 · see citing works
Food Additive P-80 Impacts Mouse Gut Microbiota Promoting Intestinal Inflammation, Obesity and Liver Dysfunction
Singh, R. K. (2016) · SOJ Microbiology & Infectious Diseases · doi:10.15226/sojmid/4/1/00148 · Cited by 87 · see citing works
Gram-Negative Flagella Glycosylation
Merino, S., & Tomás, J. M. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15022840 · Cited by 85 · see citing works
Campylobacter jejuni in Poultry: Pathogenesis and Control Strategies
Hakeem, W. G. A., Fathima, S., Shanmugasundaram, R., & Selvaraj, R. K. (2022) · Microorganisms · doi:10.3390/microorganisms10112134 · Cited by 85 · see citing works
Anti-infection mechanism of a novel dental implant made of titanium-copper (TiCu) alloy and its mechanism associated with oral microbiology
Liu, H., Tang, Y., Zhang, S., Liu, H., Wang, Z., Li, Y., Wang, X., Ren, L., Yang, K., & Qin, L. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.05.053 · Cited by 80 · see citing works
Campylobacter jejuni motility integrates specialized cell shape, flagellar filament, and motor, to coordinate action of its opposed flagella
Cohen, E. J., Nakane, D., Kabata, Y., Hendrixson, D. R., Nishizaka, T., & Beeby, M. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008620 · Cited by 77 · see citing works
Enhanced biofilm formation and multi‐host transmission evolve from divergent genetic backgrounds in C ampylobacter jejuni
Pascoe, B., Méric, G., Murray, S., Yahara, K., Mageiros, L., Bowen, R., Jones, N. H., Jeeves, R. E., Lappin-Scott, H. M., Asakura, H., et al. (2015) · Environmental Microbiology · doi:10.1111/1462-2920.13051 · Cited by 77 · see citing works
In vitro assessment of immunomodulatory and anti-Campylobacter activities of probiotic lactobacilli
Taha-Abdelaziz, K., Astill, J., Kulkarni, R. R., Read, L. R., Najarian, A., Farber, J. M., & Sharif, S. (2019) · Scientific Reports · doi:10.1038/s41598-019-54494-3 · Cited by 76 · see citing works
Metabolic and fitness determinants for in vitro growth and intestinal colonization of the bacterial pathogen Campylobacter jejuni
Gao, B., Vorwerk, H., Huber, C., Lara-Tejero, M., Mohr, J., Goodman, A. L., Eisenreich, W., Galán, J. E., & Hofreuter, D. (2017) · PLoS Biology · doi:10.1371/journal.pbio.2001390 · Cited by 76 · see citing works
Trans-Cinnamaldehyde, Carvacrol, and Eugenol Reduce Campylobacter jejuni Colonization Factors and Expression of Virulence Genes in Vitro
Upadhyay, A., Arsi, K., Wagle, B. R., Upadhyaya, I., Shrestha, S., Donoghue, A. M., & Donoghue, D. J. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00713 · Cited by 74 · see citing works
Campylobacter jejuni: targeting host cells, adhesion, invasion, and survival
Kemper, L., & Hensel, A. (2023) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12456-w · Cited by 73 · see citing works
Identification of the Flagellin Glycosylation System in Burkholderia cenocepacia and the Contribution of Glycosylated Flagellin to Evasion of Human Innate Immune Responses
Hanuszkiewicz, A., Pittock, P., Humphries, F., Moll, H., Rosales, A. R., Molinaro, A., Moynagh, P. N., Lajoie, G., & Valvano, M. A. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.562603 · Cited by 72 · see citing works
Intervention Strategies to Control Campylobacter at Different Stages of the Food Chain
Taha-Abdelaziz, K., Singh, M., Sharif, S., Sharma, S., Kulkarni, R. R., Alizadeh, M., Yitbarek, A., & Helmy, Y. A. (2023) · Microorganisms · doi:10.3390/microorganisms11010113 · Cited by 70 · see citing works
Characterization of extracellular polymeric substances from denitrifying organism Comamonas denitrificans
Andersson, S., Dalhammar, G., Land, C. J., & Rajarao, G. K. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1817-3 · Cited by 70 · see citing works
Novel Components of the Flagellar System in Epsilonproteobacteria
Gao, B., Lara-Tejero, M., Lefebre, M. D., Goodman, A. L., & Galán, J. E. (2014) · mBio · doi:10.1128/mbio.01349-14 · Cited by 67 · see citing works
Phenotypic and genotypic methods for typing Campylobacter jejuni and Campylobacter coli in poultry
Eberle, K. N., & Kiess, A. S. (2011) · Poultry Science · doi:10.3382/ps.2011-01414 · Cited by 70 · see citing works
The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2
Krause-Gruszczynska, M., Boehm, M., Rohde, M., Tegtmeyer, N., Takahashi, S., Buday, L., Oyarzábal, O. A., & Backert, S. (2011) · Cell Communication and Signaling · doi:10.1186/1478-811x-9-32 · Cited by 69 · see citing works
The Potential Link between Gut Microbiota and IgE-Mediated Food Allergy in Early Life
Molloy, J., Allen, K. J., Collier, F., Tang, M. L. K., Ward, A. C., & Vuillermin, P. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10127235 · Cited by 69 · see citing works
Distribution of Virulence-Associated Genes in a Selection of Campylobacter Isolates
Koolman, L., Whyte, P., Burgess, C. M., & Bolton, D. (2015) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2014.1883 · Cited by 66 · see citing works
Survival of Campylobacter jejuni under Conditions of Atmospheric Oxygen Tension with the Support of Pseudomonas spp
Hilbert, F., Scherwitzel, M., Paulsen, P., & Szostak, M. P. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.01532-10 · Cited by 66 · see citing works
Molecular methods to investigate adhesion, transmigration, invasion and intracellular survival of the foodborne pathogen Campylobacter jejuni
Backert, S., & Hofreuter, D. (2013) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2013.06.031 · Cited by 66 · see citing works
Novel Clinical Campylobacter jejuni Infection Models Based on Sensitization of Mice to Lipooligosaccharide, a Major Bacterial Factor Triggering Innate Immune Responses in Human Campylobacteriosis
Mousavi, S., Bereswill, S., & Heimesaat, M. M. (2020) · Microorganisms · doi:10.3390/microorganisms8040482 · Cited by 64 · see citing works
A novelO-linked glycan modulatesCampylobacter jejunimajor outer membrane protein-mediated adhesion to human histo-blood group antigens and chicken colonization
Mahdavi, J., Pirinççioğlu, N., Oldfield, N. J., Carlsohn, E., Stoof, J., Aslam, A., Self, T. J., Cawthraw, S. A., Petrovska, L., Colborne, N., et al. (2014) · Open Biology · doi:10.1098/rsob.130202 · Cited by 64 · see citing works
Molecular Mechanisms of Campylobacter Infection
van Putten, J. P. M., van Alphen, L. B., Wösten, M. M. S. M., & de Zoete, M. R. (2009) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-01846-6_7 · Cited by 62 · see citing works
Impaired Fitness and Transmission of Macrolide-Resistant Campylobacter jejuni in Its Natural Host
Luangtongkum, T., Shen, Z., Seng, V. W., Şahin, O., Jeon, B., Liu, P., & Zhang, Q. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05516-11 · Cited by 62 · see citing works
Citrus Extracts as Inhibitors of Quorum Sensing, Biofilm Formation and Motility ofCampylobacter jejuni
Castillo, S., Heredia, N. L., Aréchiga‐Carvajal, E. T., & García, S. (2014) · Food Biotechnology · doi:10.1080/08905436.2014.895947 · Cited by 61 · see citing works
Campylobacter Virulence Factors and Molecular Host–Pathogen Interactions
Tegtmeyer, N., Sharafutdinov, I., Harrer, A., Esmaeili, D. S., Linz, B., & Backert, S. (2021) · Current topics in microbiology and immunology · doi:10.1007/978-3-030-65481-8_7 · Cited by 60 · see citing works
Withdrawal of antibiotic growth promoters in China and its impact on the foodborne pathogen Campylobacter coli of swine origin
Wen, R., Li, C., Zhao, M., Wang, H., & Tang, Y. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1004725 · Cited by 60 · see citing works
Update on Campylobacter vaccine development
Poly, F., Noll, A. J., Riddle, M. S., & Porter, C. K. (2018) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2018.1528410 · Cited by 60 · see citing works
Helicobacter pylori HP0518 affects flagellin glycosylation to alter bacterial motility
Asakura, H., Churin, Y., Bauer, B., Boettcher, J. P., Bartfeld, S., Hashii, N., Kawasaki, N., Mollenkopf, H., Jungblut, P. R., Brinkmann, V., et al. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07393.x · Cited by 59 · see citing works
Enhanced Adhesion of Campylobacter jejuni to Abiotic Surfaces Is Mediated by Membrane Proteins in Oxygen-Enriched Conditions
Sulaeman, S., Hernould, M., Schaumann, A., Coquet, L., Bolla, J., Dé, E., & Tresse, O. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046402 · Cited by 58 · see citing works
Flagellar Biogenesis of Xanthomonas campestris Requires the Alternative Sigma Factors RpoN2 and FliA and Is Temporally Regulated by FlhA, FlhB, and FlgM
Yang, T., Leu, Y.-W., Chang-Chien, H.-C., & Hu, R. (2009) · Journal of Bacteriology · doi:10.1128/jb.01152-08 · Cited by 58 · see citing works
Comparative Analysis of Aerotolerance, Antibiotic Resistance, and Virulence Gene Prevalence in Campylobacter jejuni Isolates from Retail Raw Chicken and Duck Meat in South Korea
Kim, J., Park, H., Kim, J., Kim, J., Jung, J. I., Cho, S., Ryu, S., & Jeon, B. (2019) · Microorganisms · doi:10.3390/microorganisms7100433 · Cited by 58 · see citing works
Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans
Peters, S., Pascoe, B., Wu, Z., Bayliss, S., Zeng, X., Edwinson, A. L., Gurunathan, S. V., Jawahir, S., Calland, J. K., Mourkas, E., et al. (2021) · Communications Biology · doi:10.1038/s42003-021-02554-8 · Cited by 56 · see citing works
Genome-wide fitness analyses of the foodborne pathogen Campylobacter jejuni in in vitro and in vivo models
de Vries, S. P. W., Gupta, S., Baig, A., Wright, E. A., Wedley, A. L., Jensen, A. N., Lacharme‐Lora, L., Humphrey, S., Skovgård, H., Macleod, K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-01133-4 · Cited by 55 · see citing works
Review on Stress Tolerance in Campylobacter jejuni
Kim, S., Chelliah, R., Ramakrishnan, S., Perumal, A. S., Bang, W., Rubab, M., Daliri, E. B., Barathikannan, K., Elahi, F., Park, E., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.596570 · Cited by 54 · see citing works
Effects and molecular mechanism of flagellar gene flgK on the motility, adhesion/invasion, and desiccation resistance of Cronobacter sakazakii
Li, P., Zong, W., Zhang, Z., Lv, W., Ji, X., Zhu, D., Du, X., & Wang, S. (2022) · Food Research International · doi:10.1016/j.foodres.2022.112418 · Cited by 54 · see citing works
Flagellin glycosylation with pseudaminic acid in Campylobacter and Helicobacter: prospects for development of novel therapeutics
Ud-Din, A. I. M. S., & Roujeinikova, A. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2696-5 · Cited by 54 · see citing works
2(5H)-Furanone, epigallocatechin gallate, and a citric-based disinfectant disturb quorum-sensing activity and reduce motility and biofilm formation of Campylobacter jejuni
Castillo, S., Heredia, N. L., & García, S. (2014) · Folia Microbiologica · doi:10.1007/s12223-014-0344-0 · Cited by 53 · see citing works
Host-Recognition of Pathogens and Commensals in the Mammalian Intestine
Rossi, O., van Baarlen, P., & Wells, J. M. (2011) · Current topics in microbiology and immunology · doi:10.1007/82_2011_191 · Cited by 50 · see citing works
Posttranslational Modification of Flagellin FlaB in Shewanella oneidensis
Sun, L., Jin, M., Ding, W. J., Yuan, J., Kelly, J. F., & Gao, H. (2013) · Journal of Bacteriology · doi:10.1128/jb.00015-13 · Cited by 49 · see citing works
Clinical relevance of infections with zoonotic and human oral species of Campylobacter
Lee, S., Lee, J., Ha, J., Choi, Y., Kim, S., Lee, H., Yoon, Y., & Choi, K. (2016) · The Journal of Microbiology · doi:10.1007/s12275-016-6254-x · Cited by 49 · see citing works
Gene expression profiles of Vibrio parahaemolyticus in viable but non-culturable state
Meng, L., Alter, T., Aho, T., & Huehn, S. (2015) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiv035 · Cited by 48 · see citing works
Characterization of Two Campylobacter jejuni Strains for Use in Volunteer Experimental-Infection Studies
Poly, F., Read, T. D., Chen, Y., Monteiro, M. A., Serichantalergs, O., Pootong, P., Bodhidatta, L., Mason, C. J., Rockabrand, D., Baqar, S., et al. (2008) · Infection and Immunity · doi:10.1128/iai.00780-08 · Cited by 48 · see citing works
Role of the Campylobacter jejuni Cj1461 DNA Methyltransferase in Regulating Virulence Characteristics
Kim, J.-S., Li, J., Barnes, I., Baltzegar, D. A., Pajaniappan, M., Cullen, T. W., Trent, M. S., Burns, C. M., & Thompson, S. A. (2008) · Journal of Bacteriology · doi:10.1128/jb.00765-08 · Cited by 46 · see citing works
Virulence gene expression, adhesion and invasion of Campylobacter jejuni exposed to oxidative stress (H2O2)
Koolman, L., Whyte, P., Burgess, C. M., & Bolton, D. (2016) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2016.01.002 · Cited by 43 · see citing works
Identification of pathogenic genes in Campylobacter jejuni isolated from broiler carcasses and broiler slaughterhouses
Sierra-Arguello, Y. M., Perdoncini, G., Rodrigues, L. B., dos Santos, L. R., Borges, K. A., Furian, T. Q., Salle, C. T. P., Moraes, H. L. D. S., Gomes, M. J. P., & do Nascimento, V. P. (2021) · Scientific Reports · doi:10.1038/s41598-021-84149-1 · Cited by 43 · see citing works
Critical Role of LuxS in the Virulence of Campylobacter jejuni in a Guinea Pig Model of Abortion
Plummer, P. J., Şahin, O., Burrough, E. R., Sippy, R. J., Mou, K. T. Y., Rabenold, J. J., Yaeger, M. J., & Zhang, Q. (2011) · Infection and Immunity · doi:10.1128/iai.05766-11 · Cited by 43 · see citing works
Differential Glycosylation of Polar and Lateral Flagellins in Aeromonas hydrophila AH-3
Wilhelms, M., Fulton, K. M., Twine, S. M., Tomás, J. M., & Merino, S. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.376525 · Cited by 42 · see citing works
Campylobacter jejuni 81-176 forms distinct microcolonies on in vitro-infected human small intestinal tissue prior to biofilm formation
Haddock, G., Mullin, M., MacCallum, A. J., Sherry, A., Tetley, L., Watson, E. D., Dagleish, M. P., Smith, D. G., & Everest, P. H. (2010) · Microbiology · doi:10.1099/mic.0.039867-0 · Cited by 41 · see citing works
Passage of Campylobacter jejuni through the chicken reservoir or mice promotes phase variation in contingency genes Cj0045 and Cj0170 that strongly associates with colonization and disease in a mouse model
Kim, J.-S., Artymovich, K. A., Hall, D. F., Smith, E. J., Fulton, R., Bell, J. A., Dybas, L., Mansfield, L. S., Tempelman, R. J., Wilson, D. L., et al. (2012) · Microbiology · doi:10.1099/mic.0.057158-0 · Cited by 41 · see citing works
Characterization of CetA and CetB, a bipartite energy taxis system in Campylobacter jejuni
Elliott, K. T., & DiRita, V. J. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06357.x · Cited by 41 · see citing works
Sub-Inhibitory Concentrations of Trans-Cinnamaldehyde Attenuate Virulence in Cronobacter sakazakii in Vitro
Amalaradjou, M. A. R., Kim, K., & Venkitanarayanan, K. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15058639 · Cited by 40 · see citing works
How Sweet Are Our Gut Beneficial Bacteria? A Focus on Protein Glycosylation in Lactobacillus
Latousakis, D., & Juge, N. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19010136 · Cited by 40 · see citing works
Domestication of Campylobacter jejuni NCTC 11168
Pascoe, B., Williams, L., Calland, J. K., Méric, G., Hitchings, M. D., Dyer, M., Ryder, J., Shaw, S., Lopes, B. S., Chintoan‐Uta, C., et al. (2019) · Microbial Genomics · doi:10.1099/mgen.0.000279 · Cited by 40 · see citing works
Secretion Systems in Gram-Negative Bacterial Fish Pathogens
Mekasha, S., & Linke, D. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.782673 · Cited by 41 · see citing works
Transcriptomic analysis of Campylobacter jejuni NCTC 11168 in response to epinephrine and norepinephrine
Xu, F., Wu, C., Guo, F., Cui, G., Zeng, X., Yang, B., & Lin, J. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00452 · Cited by 39 · see citing works
The Mode of Biofilm Formation on Smooth Surfaces by Campylobacter jejuni
Moe, K. K., MIMURA, J., Ohnishi, T., Tomoya, W. A. K. E., Yamazaki, W., Nakai, M., & Misawa, N. (2010) · Journal of Veterinary Medical Science · doi:10.1292/jvms.09-0339 · Cited by 39 · see citing works
Update onCampylobacter jejunivaccine development for preventing human campylobacteriosis
Jagusztyn-Krynicka, E. K., Łaniewski, P., & Wyszyńska, A. (2009) · Expert Review of Vaccines · doi:10.1586/erv.09.21 · Cited by 39 · see citing works
Campylobacter jejuni and Campylobacter coli Genotyping by High-Resolution Melting Analysis of a flaA Fragment
Merchant-Patel, S., Blackall, P. J., Templeton, J. M., Price, E. P., Tong, S. Y. C., Huygens, F., & Giffard, P. M. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.01164-09 · Cited by 37 · see citing works
Behavior of two Tannerella forsythia strains and their cell surface mutants in multispecies oral biofilms
Bloch, S., Thurnheer, T., Murakami, Y., Belibasakis, G. N., & Schäffer, C. (2017) · Molecular Oral Microbiology · doi:10.1111/omi.12182 · Cited by 37 · see citing works
Phosphoglucomutase of Yersinia pestis Is Required for Autoaggregation and Polymyxin B Resistance
Felek, S., Muszyński, A., Carlson, R. W., Tsang, T. M., Hinnebusch, B. J., & Krukonis, E. S. (2010) · Infection and Immunity · doi:10.1128/iai.00997-09 · Cited by 38 · see citing works
The Involvement of the Cas9 Gene in Virulence of Campylobacter jejuni
Shabbir, M. A. B., Tang, Y., Xu, Z., Lin, M., Cheng, G., Dai, M., Wang, X., Liu, Z., Yuan, Z., & Hao, H. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00285 · Cited by 36 · see citing works
flgC gene is involved in the virulence regulation of Pseudomonas plecoglossicida and affects the immune response of Epinephelus coioides
Yang, D., Zhao, L., Li, Q., Huang, L., Qin, Y., Wang, P., Zhu, C., & Yan, Q. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.108512 · Cited by 36 · see citing works

Changes in flagellin glycosylation affect Campylobacter autoagglutination and virulence.: Mol.Microbiology
Guerry, P., Ewing, C., Schirm, M., Lorenzo, M., Kelly, J., Pattarini, D. L., Majam, G., Thibault, P., & Logan, S. (2006) · NPARC
Changes in flagellin glycosylation affect Campylobacter autoagglutination and virulence
Guerry, P., Ewing, C. P., Schirm, M., Lorenzo, M., Kelly, J., Pattarini, D., Majam, G., Thibault, P., & Logan, S. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05100.x · Cited by 265 · see citing works
Role of Flagella inCampylobacterPathogenesis
Guerry, P. (2014) · ASM Press eBooks · doi:10.1128/9781555818340.ch25 · Cited by 1 · see citing works
Research progress on flagella of Campylobacter jejuni
Fang-zh, R. (2013) · Zhongguo renshougonghuanbing zazhi · Cited by 1 · see citing works
Natural Transformation as a Tool for the Characterization of Motility Mutants of Campylobacter Jejuni 81116
Fry, B. N., Wassenaar, T. M., Zalm, R., & van der Zeijst, B. A. M. (1996) · Springer eBooks · doi:10.1007/978-1-4757-9558-5_108

Authors: Guerry, P.
Affiliations: Naval Medical Research Command (US)
Corresponding author: Guerry, Patricia
ORCID: Guerry, Patricia
Venue: Trends in Microbiology
Publisher: Elsevier BV
Published: 2007-10
Volume: 15
Issue: 10
Pages: 456-461
ISSN: 0966-842X (ISSN-L)
DOI: 10.1016/j.tim.2007.09.006
OpenAlex: W2044604878
Cited by: 339
References: 77
Citations by year: 2026: 9 · 2025: 11 · 2024: 17 · 2023: 18 · 2022: 27 · 2021: 17 · 2020: 22 · 2019: 23 · 2018: 22 · 2017: 19 · 2016: 14 · 2015: 20 · 2014: 23 · 2013: 14 · 2012: 12
FWCI: 1.82
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Microbiology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Allergy and Infectious Diseases (R01AI043559)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
Health Sciences › Medicine › Surgery › Helicobacter pylori-related gastroenterology studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords: Campylobacter jejuni, Campylobacter coli, bacterial flagellum, flagellin, flagellar motility, virulence factors, flagellar regulon, glycosylation, autoagglutination, microcolony formation, intestinal epithelial cells, diarrheal disease, pathogenesis
MeSH terms: Campylobacter, Campylobacter Infections, Flagella, Flagellin, Glycosylation, Humans, Biofilms, Virulence Factors, Gastrointestinal Tract

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Campylobacter flagella: not just for motility

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks