Cited by 197Salmonella and Campylobacter epidemiologyEscherichia coli research studiesImmune Response and Inflammation

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Life in the inflamed intestine, Salmonella style

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Santos, Renato L., Raffatellu, Manuela, Bevins, Charles L., Adams, L. Garry, Tükel, Çagla, Tsolis, Renée M., Bäumler, Andreas J.·2009·Trends in Microbiology

DOI 10.1016/j.tim.2009.08.008PMC PMC3235402

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Abstract

The lower gastrointestinal tract is densely populated with resident microbial communities (microbiota), which do not elicit overt host responses but rather provide benefit to the host, including niche protection from pathogens. However, introduction of bacteria into the underlying tissue evokes acute inflammation. Non-typhoidal Salmonella serotypes (NTS) elicit this stereotypic host response by actively penetrating the intestinal epithelium and surviving in tissue macrophages. Initial responses generated by bacterial host cell interaction are amplified in tissue through the interleukin (IL)-18/interferon-gamma and IL-23/IL-17 axes, resulting in the activation of mucosal barrier functions against NTS dissemination. However, the pathogen is adapted to survive antimicrobial defenses encountered in the lumen of the inflamed intestine. This strategy enables NTS to exploit inflammation to outcompete the intestinal microbiota, and promotes the Salmonella transmission by the fecal/oral route.

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Food-Related Illness and Death in the United States
Mead, P. S., Slutsker, L., DIETZ, V. J., McCaig, L. F., Bresee, J., Shapiro, C. A., Griffin, P. M., & Tauxe, R. V. (1999) · Emerging infectious diseases · doi:10.3201/eid0505.990502 · Cited by 7,305
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity · doi:10.1016/j.immuni.2006.01.001 · Cited by 3,605
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., et al. (2006) · Nature Medicine · doi:10.1038/nm1511 · Cited by 3,559
Pyroptosis: host cell death and inflammation
Bergsbaken, T., Fink, S. L., & Cookson, B. T. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2070 · Cited by 3,288
Surveillance for Foodborne Disease Outbreaks—United States, 2006
Gould, L. H., Walsh, K. A., Vieira, A. R., Herman, K., Williams, I. T., Hall, A. J., & Cole, D. J. (2009) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2009.11.004 · Cited by 2,372
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
Zheng, Y., Valdez, P. A., Danilenko, D. M., Hu, Y., Susan, M. L., Gong, Q., Abbas, A. R., Modrusan, Z. D., Ghilardi, N., de Sauvage, F. J., et al. (2008) · Nature Medicine · doi:10.1038/nm1720 · Cited by 1,972
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
Flo, T. H., Smith, K. D., Sato, S., Rodriguez, D. J., Holmes, M. A., Strong, R. K., Akira, S., & Aderem, A. (2004) · Nature · doi:10.1038/nature03104 · Cited by 1,877
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells
Acosta-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A., & Sallusto, F. (2007) · Nature Immunology · doi:10.1038/ni1496 · Cited by 1,857
Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine
Ivanov, I. I., Frutos, R. D. L., Manel, N., Yoshinaga, K., Rifkin, D. B., Sartor, R. B., Finlay, B. B., & Littman, D. R. (2008) · Cell Host & Microbe · doi:10.1016/j.chom.2008.09.009 · Cited by 1,770
Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense
Ye, P., Rodriguez, F. H., Kanaly, S. T., Stocking, K. L., Schurr, J. R., Schwarzenberger, P. O., Oliver, P., Huang, W., Zhang, P., Zhang, J., et al. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.4.519 · Cited by 1,522
Symbiotic bacteria direct expression of an intestinal bactericidal lectin
Cash, H. L., Whitham, C. V., Behrendt, C. L., & Hooper, L. V. (2006) · Science · doi:10.1126/science.1127119 · Cited by 1,432
The Neutrophil Lipocalin NGAL Is a Bacteriostatic Agent that Interferes with Siderophore-Mediated Iron Acquisition
Goetz, D. H., Holmes, M. A., Borregaard, N., Bluhm, M. E., Raymond, K. N., & Strong, R. K. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00708-6 · Cited by 1,355
Cutting Edge: Bacterial Flagellin Activates Basolaterally Expressed TLR5 to Induce Epithelial Proinflammatory Gene Expression
Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J., & Madara, J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.4.1882 · Cited by 1,345
Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae
Lupp, C., Robertson, M. L., Wickham, M. E., Sekirov, I., Champion, O. L., Gaynor, E. C., & Finlay, B. B. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.06.010 · Cited by 1,310
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
Cella, M., Fuchs, A. G., Vermi, W., Facchetti, F., Otero, K., Lennerz, J. K., Doherty, J. M., Mills, J. C., & Colonna, M. (2008) · Nature · doi:10.1038/nature07537 · Cited by 1,298
Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense
Satoh‐Takayama, N., Vosshenrich, C. A. J., Lesjean‐Pottier, S., Sawa, S., Lochner, M., Rattis, F. M., Mention, J., Thiam, K., Cerf–Bensussan, N., Mandelboim, O., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.11.001 · Cited by 1,133
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.-D., Özören, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., et al. (2006) · Nature Immunology · doi:10.1038/ni1346 · Cited by 1,131
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., Miller, S. I., & Aderem, A. (2006) · Nature Immunology · doi:10.1038/ni1344 · Cited by 1,127
Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense
Wilson, C. L., Ouellette, A. J., Satchell, D. P., Ayabe, T., López-Boado, Y. S., Stratman, J. L., Hultgren, S. J., Matrisian, L. M., & Parks, W. C. (1999) · Science · doi:10.1126/science.286.5437.113 · Cited by 1,076
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota
Stecher, B., Robbiani, R., Walker, A. W., Westendorf, A. M., Barthel, M., Kremer, M., Chaffron, S., Macpherson, A. J., Buer, J., Parkhill, J., et al. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050244 · Cited by 1,048
Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host
Barthel, M., Hapfelmeier, S., Quintanilla-Martínez, L., Kremer, M., Rohde, M., Hogardt, M., Pfeffer, K., Rüssmann, H., & Hardt, W.-D. (2003) · Infection and Immunity · doi:10.1128/iai.71.5.2839-2858.2003 · Cited by 1,020
Evolution in bacteria: Evidence for a universal substitution rate in cellular genomes
Ochman, H., & Wilson, A. C. (1987) · Journal of Molecular Evolution · doi:10.1007/bf02111283 · Cited by 780
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
Salzman, N. H., Ghosh, D., Huttner, K. M., Paterson, Y. Y. W., & Bevins, C. L. (2003) · Nature · doi:10.1038/nature01520 · Cited by 765
Surveillance for Foodborne Disease Outbreaks—United States, 2009-2010
del Portal, D. A., & Karras, D. J. (2013) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2013.04.001 · Cited by 719
Identification of a pathogenicity island required for Salmonella survival in host cells.
Ochman, H., Soncini, F. C., Solomon, F., & Groisman, E. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.15.7800 · Cited by 652
Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits
Brandl, K., Plitas, G., Mihu, C. N., Ubeda, C., Jia, T., Fleisher, M., Schnabl, B., DeMatteo, R. P., & Pamer, E. G. (2008) · Nature · doi:10.1038/nature07250 · Cited by 631
Determining Divergence Times of the Major Kingdoms of Living Organisms with a Protein Clock
Doolittle, R. F., Feng, D.-F., Tsang, S., Cho, G., & Little, E. (1996) · Science · doi:10.1126/science.271.5248.470 · Cited by 581
Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut
Raffatellu, M., Santos, R. L., Verhoeven, D. E., George, M. D., Wilson, R. P., Winter, S., Godinez, I., Sankaran, S., da Paixão, T. A., Gordon, M. A., et al. (2008) · Nature Medicine · doi:10.1038/nm1743 · Cited by 574
Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase
Bader, M. W., Sanowar, S., Daley, M. E., Schneider, A. R., Cho, U., Xu, W., Klevit, R. E., Moual, H. L., & Miller, S. I. (2005) · Cell · doi:10.1016/j.cell.2005.05.030 · Cited by 554
The role of microbiota in infectious disease
Stecher, B., & Hardt, W. (2008) · Trends in Microbiology · doi:10.1016/j.tim.2007.12.008 · Cited by 547
Lipocalin-2 Resistance Confers an Advantage to Salmonella enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine
Raffatellu, M., George, M. D., Akiyama, Y., Hornsby, M. J., Nuccio, S.-P., Paixao, T. A., Butler, B. P., Chu, H., Santos, R. L., Berger, T., et al. (2009) · Cell Host & Microbe · doi:10.1016/j.chom.2009.03.011 · Cited by 525
Self-citation
Salmonella infections in immunocompromised adults
Gordon, M. A. (2008) · Journal of Infection · doi:10.1016/j.jinf.2008.03.012 · Cited by 471
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury
Berger, T., Togawa, A., Duncan, G. S., Elia, A. J., You-Ten, A., Wakeham, A., Fong, H. E. H., Cheung, C. C., & Mak, T. W. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510847103 · Cited by 460
The multifaceted Paneth cell
Porter, E. M., Bevins, C. L., Ghosh, D., & Ganz, T. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-002-8412-z · Cited by 432
Self-destructive cooperation mediated by phenotypic noise
Ackermann, M., Stecher, B., Freed, N. E., Songhet, P., Hardt, W., & Doebeli, M. (2008) · Nature · doi:10.1038/nature07067 · Cited by 432
Enteric Salmonellosis Disrupts the Microbial Ecology of the Murine Gastrointestinal Tract
Barman, M., Unold, D., Shifley, K., Amir, E., Hung, K.-C., Bos, N. A., & Salzman, N. H. (2007) · Infection and Immunity · doi:10.1128/iai.01432-07 · Cited by 428
Cutting Edge: NKT Cells Constitutively Express IL-23 Receptor and RORγt and Rapidly Produce IL-17 upon Receptor Ligation in an IL-6-Independent Fashion
Rachitskaya, A. V., Hansen, A. M., Horai, R., Li, Z., Villasmil, R., Luger, D., Nussenblatt, R. B., & Caspi, R. R. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.8.5167 · Cited by 409
Non-typhoidal salmonellosis: emerging problems
Rabsch, W., Tschäpe, H., & Bäumler, A. J. (2001) · Microbes and Infection · doi:10.1016/s1286-4579(01)01375-2 · Cited by 401
The Salmonella Pathogenicity Island (SPI)-2 and SPI-1 Type III Secretion Systems Allow Salmonella Serovar typhimurium to Trigger Colitis via MyD88-Dependent and MyD88-Independent Mechanisms
Hapfelmeier, S., Stecher, B., Barthel, M., Kremer, M., Müller, A. J., Heikenwälder, M. F., Stallmach, T., Hensel, M., Pfeffer, K., Akira, S., et al. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.3.1675 · Cited by 394
MyD88-mediated signals induce the bactericidal lectin RegIIIγ and protect mice against intestinal Listeria monocytogenes infection
Brandl, K., Plitas, G., Schnabl, B., DeMatteo, R. P., & Pamer, E. G. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070563 · Cited by 385
IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells
Kimura, A., Naka, T., & Kishimoto, T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705268104 · Cited by 363
A 40 kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K‐12 chromosome
Mills, D. M., Bajaj, V., & Lee, C. A. (1995) · Molecular Microbiology · doi:10.1111/j.1365-2958.1995.tb02382.x · Cited by 359
Salmochelins, siderophores of Salmonella enterica and uropathogenic Escherichia coli strains, are recognized by the outer membrane receptor IroN
Hantke, K., Nicholson, G., Rabsch, W., & Winkelmann, G. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0737682100 · Cited by 359
Surveillance for foodborne-disease outbreaks--United States, 1993-1997.
Olsen, S. J., MacKinnon, L. C., Goulding, J. S., Bean, N. H., & Slutsker, L. (2000) · PubMed · Cited by 359
Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1 beta and tumour necrosis factor-alpha.
Cromwell, O., Hamid, Q. A., Corrigan, C. J., Barkans, J. R., Meng, Q., COLLINS, P. D., & Kay, A. B. (1992) · PubMed Central · Cited by 353
The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more
Gunn, J. S. (2008) · Trends in Microbiology · doi:10.1016/j.tim.2008.03.007 · Cited by 331
entry into host cells: the work in concert of type III secreted effector proteins
Zhou, D., & Galán, J. E. (2001) · Microbes and Infection · doi:10.1016/s1286-4579(01)01489-7 · Cited by 325
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2
Fischbach, M. A., Lin, H., Zhou, L., Yu, Y., Abergel, R. J., Liu, D. R., Raymond, K. N., Wanner, B. L., Strong, R. K., Walsh, C. T., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604636103 · Cited by 319
Contribution of Salmonella typhimurium Virulence Factors to Diarrheal Disease in Calves
Tsolis, R. M., Adams, L. G., Ficht, T. A., & Bäumler, A. J. (1999) · Infection and Immunity · doi:10.1128/iai.67.9.4879-4885.1999 · Cited by 319
Th17 cells and mucosal host defense
Aujla, S. J., Dubin, P. J., & Kolls, J. K. (2007) · Seminars in Immunology · doi:10.1016/j.smim.2007.10.009 · Cited by 316
SipA, SopA, SopB, SopD, and SopE2 Contribute to Salmonella enterica Serotype Typhimurium Invasion of Epithelial Cells
Raffatellu, M., Wilson, R. P., Chessa, D., Andrews‐Polymenis, H. L., Tran, Q. T., Lawhon, S. D., Khare, S., Adams, L. G., & Bäumler, A. J. (2004) · Infection and Immunity · doi:10.1128/iai.73.1.146-154.2005 · Cited by 311
Molecular Pathogenesis ofSalmonella entericaSerotype Typhimurium-Induced Diarrhea
Zhang, S., Kingsley, R. A., Santos, R. L., Andrews‐Polymenis, H. L., Raffatellu, M., Figueiredo, J. F., Nunes, J. S., Tsolis, R. M., Adams, L. G., & Bäumler, A. J. (2002) · Infection and Immunity · doi:10.1128/iai.71.1.1-12.2003 · Cited by 305
Host Transmission of Salmonella enterica Serovar Typhimurium Is Controlled by Virulence Factors and Indigenous Intestinal Microbiota
Lawley, T. D., Bouley, D. M., Hoy-Schulz, Y. E., Gerke, C., Relman, D. A., & Monack, D. M. (2007) · Infection and Immunity · doi:10.1128/iai.01189-07 · Cited by 303
5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.
Madara, J., Patapoff, T. W., Gillece-Castro, B. L., Colgan, S. P., Parkos, C. A., Delp, C., & Mrsny, R. J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116462 · Cited by 290
Salmonella entericaSerovar Typhimurium Pathogenicity Island 2 Is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis
Coburn, B. A., Li, Y., Owen, D., Vallance, B. A., & Finlay, B. B. (2005) · Infection and Immunity · doi:10.1128/iai.73.6.3219-3227.2005 · Cited by 204
A mouse model for S. typhimurium-induced enterocolitis
Hapfelmeier, S., & Hardt, W. (2005) · Trends in Microbiology · doi:10.1016/j.tim.2005.08.008 · Cited by 199
Motility allows S. Typhimurium to benefit from the mucosal defence
Stecher, B., Barthel, M., Schlumberger, M. C., Haeberli, L., Rabsch, W., Kremer, M., & Hardt, W. (2008) · Cellular Microbiology · doi:10.1111/j.1462-5822.2008.01118.x · Cited by 198
CsgA is a pathogen‐associated molecular pattern of Salmonella enterica serotype Typhimurium that is recognized by Toll‐like receptor 2
Tükel, Ç., Raffatellu, M., Humphries, A. D., Wilson, R. P., Andrews‐Polymenis, H. L., Gull, T. B., Figueiredo, J. F., Wong, M. H., Michelsen, K. S., Akçelik, N., et al. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.04825.x · Cited by 192
Responses to Amyloids of Microbial and Host Origin Are Mediated through Toll-like Receptor 2
Tükel, Ç., Wilson, R. P., Nishimori, J. H., Pezeshki, M., Chromy, B. A., & Bäumler, A. J. (2009) · Cell Host & Microbe · doi:10.1016/j.chom.2009.05.020 · Cited by 190
Biosynthesis and IroC‐dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar Typhimurium
Crouch, M. V., Castor, M., Karlinsey, J. E., Kalhorn, T., & Fang, F. C. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.06089.x · Cited by 187
Bacteremia in febrile Malawian children: clinical and microbiologic features
WALSH, A. L., PHIRI, A. J., Graham, S. M., MOLYNEUX, E. M., & Molyneux, M. E. (2000) · The Pediatric Infectious Disease Journal · doi:10.1097/00006454-200004000-00010 · Cited by 184
In vivo, fliC expression by Salmonella enterica serovar Typhimurium is heterogeneous, regulated by ClpX, and anatomically restricted
Cummings, L. A., Wilkerson, W. D., Bergsbaken, T., & Cookson, B. T. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05271.x · Cited by 179
Injection of Flagellin into the Host Cell Cytosol by Salmonella enterica Serotype Typhimurium
Sun, Y., Rolán, H. G., & Tsolis, R. M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.c700181200 · Cited by 171
Immunity to Systemic Salmonella Infections
Mastroeni, P. (2002) · Current Molecular Medicine · doi:10.2174/1566524023362492 · Cited by 168
Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine
Godinez, I., Raffatellu, M., Chu, H., da Paixão, T. A., Haneda, T., Santos, R. L., Bevins, C. L., Tsolis, R. M., & Bäumler, A. J. (2008) · Infection and Immunity · doi:10.1128/iai.00933-08 · Cited by 163
T Cells Help To Amplify Inflammatory Responses Induced bySalmonella entericaSerotype Typhimurium in the Intestinal Mucosa
Godinez, I., Haneda, T., Raffatellu, M., George, M. D., da Paixão, T. A., Rolán, H. G., Santos, R. L., Dandekar, S., Tsolis, R. M., & Bäumler, A. J. (2008) · Infection and Immunity · doi:10.1128/iai.01691-07 · Cited by 153
Manipulating cellular transport and immune responses: dynamic interactions between intracellular Salmonella enterica and its host cells
Abrahams, G. L., & Hensel, M. (2006) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00706.x · Cited by 152
The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation
Müller, A. J., Hoffmann, C., Galle, M., Broeke, A. V. D., Heikenwälder, M. F., Falter, L., Misselwitz, B., Kremer, M., Beyaert, R., & Hardt, W. (2009) · Cell Host & Microbe · doi:10.1016/j.chom.2009.07.007 · Cited by 150
Morphologic and Molecular Characterization of Salmonella typhimurium Infection in Neonatal Calves
Santos, R. L., Zhang, S., Tsolis, R. M., Bäumler, A. J., & Adams, L. G. (2002) · Veterinary Pathology · doi:10.1354/vp.39-2-200 · Cited by 148
IroN, a Novel Outer Membrane Siderophore Receptor Characteristic of Salmonella enterica
Bäumler, A. J., Norris, T. L., Lasco, T., Voigt, W., Reissbrodt, R., Rabsch, W., & Heffron, F. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.6.1446-1453.1998 · Cited by 147
PhoP‐regulated Salmonella resistance to the antimicrobial peptides magainin 2 and polymyxin B
Shi, Y., Cromie, M. J., Hsu, F., TURK, J. W., & Groisman, E. A. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04107.x · Cited by 138
SalmonellaHost Cell Invasion Emerged by Acquisition of a Mosaic of Separate Genetic Elements, IncludingSalmonellaPathogenicity Island 1 (SPI1), SPI5, andsopE2
Mirold, S., Ehrbar, K., Weissmüller, A., Prager, R., Tschäpe, H., Rüssmann, H., & Hardt, W. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.7.2348-2358.2001 · Cited by 133
The record of horizontal gene transfer in Salmonella
Bäumler, A. J. (1997) · Trends in Microbiology · doi:10.1016/s0966-842x(97)01082-2 · Cited by 132
Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12
Hensel, M., Shea, J. E., Bäumler, A. J., Gleeson, C., Blattner, F. R., & Holden, D. W. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.4.1105-1111.1997 · Cited by 124
Salmonella enterica serotype Typhimurium Std fimbriae bind terminal α(1,2)fucose residues in the cecal mucosa
Chessa, D., Winter, M. G., Jakomin, M., & Bäumler, A. J. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06566.x · Cited by 124
Rapid detection of Salmonella enterica with primers specific for iroB
Bäumler, A. J., Heffron, F., & Reissbrodt, R. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.5.1224-1230.1997 · Cited by 118
T lymphocytes in host defense against bacterial translocation from the gastrointestinal tract
Gautreaux, M. D., Deitch, E. A., & Berg, R. D. (1994) · Infection and Immunity · doi:10.1128/iai.62.7.2874-2884.1994 · Cited by 114
Murine NKT cells produce Th17 cytokine interleukin-22
Goto, M., Murakawa, M., Kadoshima-Yamaoka, K., Tanaka, Y., Nagahira, K., Fukuda, Y., & Nishimura, T. (2008) · Cellular Immunology · doi:10.1016/j.cellimm.2008.10.002 · Cited by 112
Molecular Epidemiology of 3 Putative Virulence Genes forEscherichia coliUrinary Tract Infection—usp, iha,andiroNE. coli
Bauer, R., Zhang, L., Foxman, B., Siitonen, A., Jantunen, M. E., Saxén, H., & Marrs, C. F. (2002) · The Journal of Infectious Diseases · doi:10.1086/340206 · Cited by 107
Instruments of microbial warfare: Bacteriocin synthesis, toxicity and immunity
Baba, T., & Schneewind, O. (1998) · Trends in Microbiology · doi:10.1016/s0966-842x(97)01196-7 · Cited by 104
The crucial role of polymorphonuclear leukocytes in resistance to Salmonella dublin infections in genetically susceptible and resistant mice
Vassiloyanakopoulos, A. P., Okamoto, S., & Fierer, J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7676 · Cited by 103
Contribution of Flagellin Pattern Recognition to Intestinal Inflammation duringSalmonella entericaSerotype Typhimurium Infection
Winter, S., Thiennimitr, P., Nuccio, S., Haneda, T., Winter, M. G., Wilson, R. P., Russell, J. M., Henry, T., Tran, Q. T., Lawhon, S. D., et al. (2009) · Infection and Immunity · doi:10.1128/iai.01341-08 · Cited by 101
Developmentally Regulated Intestinal Expression of IFN-γ and Its Target Genes and the Age-Specific Response to Enteric Salmonella Infection
Rhee, S., Walker, W. A., & Cherayil, B. J. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.2.1127 · Cited by 99
The impact of bacteraemia on HIV infection. Nine years experience in a large Italian University Hospital
Tumbarello, M., Tacconelli, E., Caponera, S., Cauda, R., & Ortona, L. (1995) · Journal of Infection · doi:10.1016/s0163-4453(95)92110-9 · Cited by 96
Paneth Cell α-Defensin Synthesis and Function
Ouellette, A. J. (2006) · Springer eBooks · doi:10.1007/3-540-29916-5_1 · Cited by 95
The Capsule Encoding theviaBLocus Reduces Interleukin-17 Expression and Mucosal Innate Responses in the Bovine Intestinal Mucosa during Infection withSalmonella entericaSerotype Typhi
Raffatellu, M., Santos, R. L., Chessa, D., Wilson, R. P., Winter, S., Rossetti, C., Lawhon, S. D., Chu, H., Lau, T., Bevins, C. L., et al. (2007) · Infection and Immunity · doi:10.1128/iai.01571-06 · Cited by 93
Characterization of an iroBCDEN Gene Cluster on a Transmissible Plasmid of Uropathogenic Escherichia coli : Evidence for Horizontal Transfer of a Chromosomal Virulence Factor
Sorsa, L. J., Dufke, S., Heesemann, J., & Schubert, S. (2003) · Infection and Immunity · doi:10.1128/iai.71.6.3285-3293.2003 · Cited by 85
Secreted Effector Proteins ofSalmonella entericaSerotype Typhimurium Elicit Host-Specific Chemokine Profiles in Animal Models of Typhoid Fever and Enterocolitis
Zhang, S., Adams, L. G., Nunes, J. S., Khare, S., Tsolis, R. M., & Bäumler, A. J. (2003) · Infection and Immunity · doi:10.1128/iai.71.8.4795-4803.2003 · Cited by 81
Non-typhoidal Salmonella Bacteraemia Without Gastroenteritis: a Marker of Underlying Immunosuppression. Review of Casesat St. Thomas' Hospital 1970–1999
Brown, M. J., & Eykyn, S. J. (2000) · Journal of Infection · doi:10.1053/jinf.2000.0750 · Cited by 74
Genetic flux over time in the Salmonella lineage
Vernikos, G. S., Thomson, N. R., & Parkhill, J. (2007) · Genome biology · doi:10.1186/gb-2007-8-6-r100 · Cited by 74
Innate Immune Activation of CD4 T Cells in Salmonella-Infected Mice Is Dependent on IL-18
Srinivasan, A., Salazar-Gonzalez, R.-M., Jarcho, M. P., Sandau, M. M., Lefrançois, L., & McSorley, S. J. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.10.6342 · Cited by 70
Neutrophils prevent extracellular colonization of the liver microvasculature by Salmonella typhimurium
Conlan, J. W. (1996) · Infection and Immunity · doi:10.1128/iai.64.3.1043-1047.1996 · Cited by 63
Production of IL-12, IL-23 and IL-27p28 by bone marrow-derived conventional dendritic cells rather than macrophages after LPS/TLR4-dependent induction by Salmonella Enteritidis
Siegemund, S., Schütze, N., Freudenberg, M. A., Lutz, M. B., Straubinger, R. K., & Alber, G. (2007) · Immunobiology · doi:10.1016/j.imbio.2007.09.004 · Cited by 52
Neutrophil influx during non-typhoidal salmonellosis: who is in the driver's seat?
kel, Ã. T. ⁄., Raffatellu, M., Chessa, D., Wilson, R. P., AkÃ§elik, M., & Bäumler, A. J. (2006) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2006.00051.x · Cited by 46
Salmonella meningitis in children in Blantyre, Malawi, 1996–1999
MOLYNEUX, E. M., Walsh, A. L., Malenga, G. J., Rogerson, S. J., & Molyneux, M. E. (2000) · Annals of Tropical Paediatrics · doi:10.1080/02724930092057 · Cited by 42
RosE represses Std fimbrial expression in Salmonella enterica serotype Typhimurium
Chessa, D., Winter, M. G., Nuccio, S., Tükel, Ç., & Bäumler, A. J. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06185.x · Cited by 38
Salmonella infections in a cancer center
Noriega, L. M., van der Auwera, P., DANEAU, D., Meunier, F., & Aoun, M. (1994) · Supportive Care in Cancer · doi:10.1007/bf00572093 · Cited by 32
Salmonella bacteremia in African patients with human immunodeficiency virus infection
Wit, S. D., Taelman, H., de Perre, P. V., Rouvroy, D., & Clumeck, N. (1988) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/bf01962170 · Cited by 24

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Gut inflammation provides a respiratory electron acceptor for Salmonella
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Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota
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Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut
Liu, J. Z., Jellbauer, S., Poe, A. J., Ton, V., Pesciaroli, M., Kehl-Fie, T. E., Restrepo, N. A., Hosking, M. P., Edwards, R. A., Battistoni, A., et al. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.01.017 · Cited by 328
Self-citation
Salmonella Typhimurium and inflammation: a pathogen-centric affair
Galán, J. E. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00561-4 · Cited by 334
Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons
Deriu, E., Boxx, G. M., He, X., Pan, C., Benavidez, S. D., Cen, L., Rozengurt, N., Shi, W., & Cheng, G. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005572 · Cited by 280

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Authors: Santos, R. L., Raffatellu, M., Bevins, C. L., Adams, L. G., Tükel, Ç., Tsolis, R. M., & Bäumler, A. J.
Affiliations: Universidade Federal de Minas Gerais (BR)
University of California, Irvine (US)
University of California, Davis (US)
Texas A&M University (US)
Corresponding author: Bäumler, Andreas J.
ORCID: Santos, Renato L.
Raffatellu, Manuela
Bevins, Charles L.
Adams, L. Garry
Tsolis, Renée M.
Bäumler, Andreas J.
Venue: Trends in Microbiology
Publisher: Elsevier BV
Published: 2009-11
Volume: 17
Issue: 11
Pages: 498-506
ISSN: 0966-842X (ISSN-L)
DOI: 10.1016/j.tim.2009.08.008
PMC: PMC3235402
OpenAlex: W2075058732
Cited by: 197
References: 100
Citations by year: 2026: 5 · 2025: 8 · 2024: 3 · 2023: 10 · 2022: 11 · 2021: 8 · 2020: 10 · 2019: 13 · 2018: 8 · 2017: 12 · 2016: 15 · 2015: 15 · 2014: 12 · 2013: 19 · 2012: 17
FWCI: 2.13
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Microbiology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Allergy and Infectious Diseases (R01AI044170, AI 040124, AI044170, AI079173, R21AI079173, R01AI032738, R29AI040124, R01AI050843, R01AI076246, R01AI040124, R01AI050553, AI050553, AI076246, R37AI032738)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
Life Sciences › Immunology and Microbiology › Microbiology › Escherichia coli research studies
Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Keywords: non-typhoidal Salmonella, intestinal inflammation, host-pathogen interaction, gut microbiota, tissue macrophages, IL-23/IL-17 axis, mucosal barrier, antimicrobial resistance, fecal-oral transmission
MeSH terms: Animals, Humans, Intestinal Mucosa, Intestines, Macrophages, Models, Biological, Salmonella, Salmonella Infections, Cytokines

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