Cited by 452MicroRNA in disease regulationNeuroinflammation and Neurodegeneration MechanismsGenetics and Neurodevelopmental Disorders

The DOI matches its Crossref record; 93 of the 94 references it cites were found in a registry or an index.

Alterations of the microRNA network cause neurodegenerative disease

Hébert, Sébastien S., De Strooper, Bart·2009·Trends in Neurosciences

DOI 10.1016/j.tins.2008.12.003

Open this paper in CoChat — free account

Abstract

Brain development crucially depends on the integrity of microRNA (miRNA) pathways, which function at the post-transcriptional level as a rheostat of the transcriptome and proteome of the cell. miRNAs are also involved in many other, more specific, aspects of neuronal function such as neurite outgrowth and synapse formation. Complete loss of miRNA expression in the brain leads to neurodegeneration in several animal models. Evidence from patient material is emerging that miRNA dysregulation could, indeed, contribute to neurodegenerative disorders. The translation of proteins previously implicated in familial forms of disease seems to be under control of miRNAs, and changes in miRNAs might explain how these proteins become affected in sporadic neurodegenerative disease. Thus, miRNAs are moving rapidly center stage as key regulators of neuronal development and function in addition to important contributors to neurodegenerative disorder.

Integrity signals

Registry

Crossref · 10.1016/j.tins.2008.12.003

Cites

93 of 93 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

RETRACTED: Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts
Kuhn, D. E., Nuovo, G. J., Martin, M. M., Malana, G. E., Pleister, A. P., Jiang, J., Schmittgen, T. D., Terry, A. V., Gardiner, K., Head, E., et al. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.03.120 · Cited by 153
Retracted
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948
Identification of Novel Genes Coding for Small Expressed RNAs
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956
MicroRNA genes are transcribed by RNA polymerase II
Lee, Y., Kim, M., Han, J., Yeom, K.-H., Lee, S., Baek, S. H., & Kim, V. N. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600385 · Cited by 4,556
Alzheimer's Disease Is a Synaptic Failure
Selkoe, D. J. (2002) · Science · doi:10.1126/science.1074069 · Cited by 4,420
α-Synuclein Locus Triplication Causes Parkinson's Disease
Singleton, A. B., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R., et al. (2003) · Science · doi:10.1126/science.1090278 · Cited by 4,383
Silencing of microRNAs in vivo with ‘antagomirs’
Krützfeldt, J., Rajewsky, N., Braich, R., Rajeev, K. G., Tuschl, T., Manoharan, M., & Stoffel, M. (2005) · Nature · doi:10.1038/nature04303 · Cited by 3,949
Human MicroRNA Targets
John, B., Enright, A. J., Aravin, A., Tuschl, T., Sander, C., & Marks, D. S. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020363 · Cited by 3,796
RAS Is Regulated by the let-7 MicroRNA Family
Johnson, S., Großhans, H., Shingara, J., Byrom, M., JARVIS, R., Cheng, A., Labourier, E., Reinert, K. L., Brown, D., & Slack, F. J. (2005) · Cell · doi:10.1016/j.cell.2005.01.014 · Cited by 3,699
The Microprocessor complex mediates the genesis of microRNAs
Gregory, R. I., Yan, K.-P., Amuthan, G., Chendrimada, T. P., Doratotaj, B., Cooch, N. S., & Shiekhattar, R. (2004) · Nature · doi:10.1038/nature03120 · Cited by 2,851

Flagged first, then by citations

Show all 94 references

1 of the 94 references couldn’t be matched to a known paper.

Sorted by citations

Items 101–200 of 452

Morphine Regulates Dopaminergic Neuron Differentiation via miR-133b
Sánchez-Simón, F. M., Zhang, X. X., Loh, H. H., Law, P., & Rodríguez, R. E. (2010) · Molecular Pharmacology · doi:10.1124/mol.110.066837 · Cited by 109
miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease
Barros-Viegas, A. T., Carmona, V., Ferreiro, E. B., Guedes, J. R., Cardoso, A. M., Cunha, P. S., de Almeida, L. P., Oliveira, C. R., Peça, J., Peça, J., et al. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2020.01.010 · Cited by 112
MicroRNA miR124 is required for the expression of homeostatic synaptic plasticity
Hou, Q., Ruan, H., Gilbert, J. P., Wang, G., Ma, Q., Yao, W., & Man, H. (2015) · Nature Communications · doi:10.1038/ncomms10045 · Cited by 106
Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53
Gefen, N., Binder, V., Zaliova, M. K., Linka, Y., Morrow, M., Novosel, A., Edry, L., Hertzberg, L., Shomron, N., Williams, O., et al. (2009) · Leukemia · doi:10.1038/leu.2009.208 · Cited by 106
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition
Yang, L., Han, B., Zhang, Y., Bai, Y., Chao, J., Hu, G., & Yao, H. (2017) · Autophagy · doi:10.1080/15548627.2017.1414755 · Cited by 103
Neuroprotective Effects and Therapeutic Potential of the Citrus Flavonoid Hesperetin in Neurodegenerative Diseases
Evans, J. A., Mendonca, P., & Soliman, K. F. A. (2022) · Nutrients · doi:10.3390/nu14112228 · Cited by 111
miR-29c regulates BACE1 protein expression
Zong, Y., Wang, H., Dong, W., Quan, X., Zhu, H., Xu, Y., Huang, L., Ma, C., & Qin, C. (2011) · Brain Research · doi:10.1016/j.brainres.2011.04.035 · Cited by 117
Converging miRNA functions in diverse brain disorders: A case for miR-124 and miR-126
Sonntag, K., Woo, T.-U. W., & Krichevsky, A. M. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.11.035 · Cited by 107
NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells
Lukiw, W. J. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2011.11.022 · Cited by 80
MicroRNA-124–Mediated Regulation of Inhibitory Member of Apoptosis-Stimulating Protein of p53 Family in Experimental Stroke
Liu, X., Li, F., Zhao, S., Luo, Y., Kang, J. P., Zhao, H., Yan, F., Li, S., & Ji, X. (2013) · Stroke · doi:10.1161/strokeaha.111.000613 · Cited by 104
Brain‐Penetration and Neuron‐Targeting DNA Nanoflowers Co‐Delivering miR‐124 and Rutin for Synergistic Therapy of Alzheimer's Disease
Ouyang, Q., Liu, K., Zhu, Q., Deng, H., Le, Y., Ouyang, W., Yan, X., Zhou, W., & Tong, J. (2022) · Small · doi:10.1002/smll.202107534 · Cited by 94
miR-20a regulates expression of the iron exporter ferroportin in lung cancer
Babu, K. R., & Muckenthaler, M. U. (2015) · Journal of Molecular Medicine · doi:10.1007/s00109-015-1362-3 · Cited by 101
Up‐regulation of the mitochondrial malate dehydrogenase by oxidative stress is mediated by miR‐743a
Shi, Q., & Gibson, G. E. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07333.x · Cited by 100
Northern blotting analysis of microRNAs, their precursors and RNA interference triggers
Kościańska, E., Staręga‐Rosłan, J., Sznajder, Ł. J., Olejniczak, M., Galka-Marciniak, P., & Krzyżosiak, W. J. (2011) · BMC Molecular Biology · doi:10.1186/1471-2199-12-14 · Cited by 95
Micro RNA let‐7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis
Guan, H., Fan, D., Mrelashvili, D., Hao, H., Singh, N. P., Singh, U. P., Nagarkatti, P. S., & Nagarkatti, M. (2012) · European Journal of Immunology · doi:10.1002/eji.201242702 · Cited by 91
Modification of Cognitive Performance in Schizophrenia by Complexin 2 Gene Polymorphisms
Begemann, M., Grube, S., Papiol, S., Malzahn, D., Krampe, H., Ribbe, K., Friedrichs, H., Radyushkin, K., El-Kordi, A., Benseler, F., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.107 · Cited by 94
MicroRNA-Related Cofilin Abnormality in Alzheimer's Disease
Yao, J., Hennessey, T., Flynt, A. S., Lai, E. C., Beal, M. F., & Lin, M. T. S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015546 · Cited by 93
MicroRNA networks surrounding APP and amyloid-β metabolism — Implications for Alzheimer's disease
Schönrock, N., Matamales, M., Ittner, L. M., & Götz, J. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.11.013 · Cited by 96
miRNA dosage control in development and human disease
Cui, Y., Qi, Y., Ding, L., Ding, S., Han, Z., Wang, Y., & Du, P. (2023) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.05.009 · Cited by 90
Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death
McKiernan, R. C., Jimenez-Mateos, E. M., Sano, T., Bray, I. M., Stallings, R. L., Simon, R. P., & Henshall, D. C. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.06.029 · Cited by 89
RETRACTED: MicroRNA-125b promotes neurons cell apoptosis and Tau phosphorylation in Alzheimer’s disease
Ma, X., Liu, L., & Meng, J. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.09.043 · Cited by 91
Retracted
Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment
Weinberg, R. B., Mufson, E. J., & Counts, S. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00430 · Cited by 90
MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase‐6 regulates astrocyte survival
Noorbakhsh, F., Ramachandran, R., Barsby, N. L., Ellestad, K. K., LeBlanc, A. C., Dickie, P., Baker, G. B., Hollenberg, M. D., Cohen, É. A., & Power, C. (2010) · The FASEB Journal · doi:10.1096/fj.09-147819 · Cited by 87
miR‐181a/b downregulation exerts a protective action on mitochondrial disease models
Indrieri, A., Carrella, S., Romano, A., Spaziano, A., Marrocco, E., Fernández‐Vizarra, E., Barbato, S., Pizzo, M., Ezhova, Y., Golia, F. M., et al. (2019) · EMBO Molecular Medicine · doi:10.15252/emmm.201708734 · Cited by 87
Epigenetic drug discovery for Alzheimer’s disease
Cacabelos, R., & Torrellas, C. (2014) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2014.930124 · Cited by 88
Modes of Aβ toxicity in Alzheimer’s disease
Götz, J., Eckert, A., Matamales, M., Ittner, L. M., & Liu, X. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0750-2 · Cited by 87
MicroRNAs: novel therapeutic targets in neurodegenerative diseases
Roshan, R., Ghosh, T., Scaria, V., & Pillai, B. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2009.09.009 · Cited by 88
The Outflow Pathway: A Tissue With Morphological and Functional Unity
Saccà, S. C., Gandolfi, S., Bagnis, A., Manni, G., Damonte, G., Traverso, C. E., & Izzotti, A. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25305 · Cited by 83
Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10
Augustin, R., Endres, K., Reinhardt, S., Kuhn, P., Lichtenthaler, S. F., Hansen, J., Wurst, W., & Trümbach, D. (2012) · BMC Medical Genetics · doi:10.1186/1471-2350-13-35 · Cited by 82
miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT
Chen, J., Zhang, H., Chen, Y., Qiao, G., Jiang, W., Ni, P., Liu, X., & Ma, L. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.01.022 · Cited by 81
Role of miRNAs in Neurodegeneration: From Disease Cause to Tools of Biomarker Discovery and Therapeutics
Roy, B., Lee, E. J., Li, T., & Rampersaud, M. (2022) · Genes · doi:10.3390/genes13030425 · Cited by 83
Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures
van Spronsen, M., van Battum, E. Y., Kuijpers, M., Vangoor, V. R., Rietman, M. L., Pothof, J., Gumy, L. F., van IJcken, W. F. J., Akhmanova, A., Pasterkamp, R. J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074907 · Cited by 82
Modulation of central nervous system–specific microRNA-124a alters the inflammatory response in the formalin test in mice
Kynast, K. L., Russe, O. Q., Möser, C. V., Geißlinger, G., & Niederberger, E. (2012) · Pain · doi:10.1016/j.pain.2012.11.010 · Cited by 80
miRNAs as Circulating Biomarkers for Alzheimer's Disease and Parkinson's Disease
Mushtaq, G., H. Greig, N., Anwar, F., A. Zamzami, M., Choudhry, H., M. Shaik, M., A. Tamargo, I., & A. Kamal, M. (2016) · Medicinal Chemistry · doi:10.2174/1573406411666151030112140 · Cited by 78
The Implications of ncRNAs in the Development of Human Diseases
López-Jiménez, E. A., & Andrés‐León, E. (2021) · Non-Coding RNA · doi:10.3390/ncrna7010017 · Cited by 83
Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
Saiyed, A. N., Vasavada, A. R., & Johar, K. (2022) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-022-00413-9 · Cited by 79
Dendritic Spine and Synaptic Plasticity in Alzheimer’s Disease: A Focus on MicroRNA
Reza-Zaldívar, E. E., Hernández-Sapiéns, M. A., Minjarez, B. D., Gómez‐Pinedo, U., Sánchez-González, V., Márquez-Aguirre, A. L., & Canales-Aguirre, A. A. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00255 · Cited by 81
Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction
Dhahbi, J. M., Spindler, S. R., Atamna, H., Yamakawa, A., Guerrero, N., Boffelli, D., Mote, P., & Martin, D. I. (2013) · Aging · doi:10.18632/aging.100540 · Cited by 75
Studying micro RNA Function and Dysfunction in Alzheimer’s Disease
Lukiw, W. J., Андреева, Т. В., Grigorenko, A. P., & Rogaev, E. I. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2012.00327 · Cited by 76
Mirnas as Biomarkers of Neurodegenerative Disorders
Viswambharan, V., Thanseem, I., Vasu, M. M., Poovathinal, S. A., & Anitha, A. (2017) · Biomarkers in Medicine · doi:10.2217/bmm-2016-0242 · Cited by 76
Emerging Roles for 3′ UTRs in Neurons
Bae, B., & Miura, P. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103413 · Cited by 77
High-performance quantification of mature microRNAs by real-time RT-PCR using deoxyuridine-incorporated oligonucleotides and hemi-nested primers
Wan, G., Lim, Q. ‘., & Too, H. (2010) · RNA · doi:10.1261/rna.2001610 · Cited by 75
Procyanidins and Alzheimer’s Disease
Zhao, S., Zhang, L., Yang, C., Li, Z., & Rong, S. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1469-6 · Cited by 75
lncRNA MALAT1/miR-205-5p axis regulates MPP+-induced cell apoptosis in MN9D cells by directly targeting LRRK2.
Chen, Q., Huang, X., & Li, R. (2018) · PubMed Central · Cited by 74
Opposing actions of environmental enrichment and Alzheimer’s disease on the expression of hippocampal microRNAs in mouse models
Barak, B., Shvarts-Serebro, I., Modai, S., Gilam, A., Okun, E., Michaelson, D. M., Mattson, M. P., Shomron, N., & Ashery, U. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.77 · Cited by 75
Chronic Intermittent Ethanol Exposure and Its Removal Induce a Different miRNA Expression Pattern in Primary Cortical Neuronal Cultures
Guo, Y., Chen, Y., Carreon, S., & Qiang, M. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01689.x · Cited by 75
MiR-299-5p regulates apoptosis through autophagy in neurons and ameliorates cognitive capacity in APPswe/PS1dE9 mice
Zhang, Y., Liu, C., Wang, J., Li, Q., Ping, H., Gao, S., & Wang, P. (2016) · Scientific Reports · doi:10.1038/srep24566 · Cited by 73
Neurodegeneration the RNA way
Renoux, A. J., & Todd, P. K. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.10.006 · Cited by 75
MicroRNAs underlying memory deficits in neurodegenerative disorders
Hernandez-Rapp, J., Rainone, S., & Hébert, S. S. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.04.011 · Cited by 74
Self-citation
Downregulation of miR-199b promotes the acute spinal cord injury through IKKβ-NF-κB signaling pathway activating microglial cells
Zhou, H.-J., Wang, L.-Q., Xu, Q.-S., Fan, Z.-X., Zhu, Y., Jiang, H., Zheng, X.-J., Ma, Y.-H., & Zhan, R.-Y. (2016) · Experimental Cell Research · doi:10.1016/j.yexcr.2016.09.020 · Cited by 64
MicroRNAs in Human Diseases: From Autoimmune Diseases to Skin, Psychiatric and Neurodegenerative Diseases
Ha, T.-Y. (2011) · Immune Network · doi:10.4110/in.2011.11.5.227 · Cited by 72
Swimming attenuates d -galactose-induced brain aging via suppressing miR-34a-mediated autophagy impairment and abnormal mitochondrial dynamics
Kou, X., Li, J., Liu, X., Chang, J., Zhao, Q., Jia, S., Fan, J., & Chen, N. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00018.2017 · Cited by 73
Normal Midbrain Dopaminergic Neuron Development and Function in miR-133b Mutant Mice
Heyer, M. P., Pani, A. K., Smeyne, R. J., Kenny, P. J., & Feng, G. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1732-12.2012 · Cited by 71
MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases
Provost, P. (2010) · Brain Research · doi:10.1016/j.brainres.2010.03.069 · Cited by 70
UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation
Subramanian, M., Hyeon, S. J., Das, T., Suh, Y. S., Kim, Y. K., Lee, J.-S., Song, E. J., Ryu, H., & Yu, K. (2021) · Nature Communications · doi:10.1038/s41467-021-23597-9 · Cited by 62
MicroRNAs and the Regulation of Tau Metabolism
Hébert, S. S., Sergeant, N., & Buée, L. (2012) · International Journal of Alzheimer s Disease · doi:10.1155/2012/406561 · Cited by 72
Self-citation
Aberration of miRNAs expression in leukocytes from sporadic amyotrophic lateral sclerosis
Chen, Y., Wei, Q., Chen, X., Li, C., Cao, B., Ou, R., Hadano, S., & Shang, H.-F. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00069 · Cited by 69
Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease
Chen, D., Lan, G., Li, R., Mei, Y., Shui, X., Gu, X., Wang, L., Zhang, T., Gan, C., Xia, Y., et al. (2022) · Translational Neurodegeneration · doi:10.1186/s40035-022-00302-4 · Cited by 68
Light-activated CRISPR-Cas12a for amplified imaging of microRNA in cell cycle phases at single-cell levels
Liu, H., Dong, J., Duan, Z., Xia, F., Willner, I., & Huang, F. (2024) · Science Advances · doi:10.1126/sciadv.adp6166 · Cited by 68
microRNAs in Neurodegeneration: Current Findings and Potential Impacts
Sharma, S., & Lu, H. (2018) · Journal of Alzheimer’s Disease & Parkinsonism · doi:10.4172/2161-0460.1000420 · Cited by 67
Soluble Beta-Amyloid Peptides, but Not Insoluble Fibrils, Have Specific Effect on Neuronal MicroRNA Expression
Li, J. J., Dolios, G., Wang, R., & Liao, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090770 · Cited by 65
miR-494-3p modulates the progression of in vitro and in vivo Parkinson’s disease models by targeting SIRT3
Geng, L., Zhang, T., Liu, W., & Chen, Y. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.03.037 · Cited by 65
miR-9-5p modulates the progression of Parkinson’s disease by targeting SIRT1
Wang, Z., Sun, L., Jia, K., Wang, X., & Wang, X. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.02.038 · Cited by 66
The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review
Danborg, P. B., Simonsen, A. H., Waldemar, G., & Heegaard, N. H. H. (2014) · Biomarkers · doi:10.3109/1354750x.2014.904001 · Cited by 63
Human Brain Injury and miRNAs: An Experimental Study
Sessa, F., Maglietta, F., Bertozzi, G., Salerno, M., Mizio, G. D., Messina, G., Montana, A., Ricci, P., & Pomara, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071546 · Cited by 63
The Impact of MicroRNAs on Brain Aging and Neurodegeneration
Persengiev, S. P., Kondova, I. I., & Bontrop, R. E. (2012) · Current Gerontology and Geriatrics Research · doi:10.1155/2012/359369 · Cited by 61
MicroRNA function and neurotrophin BDNF
Numakawa, T., Richards, M., Adachi, N., Kishi, S., Kunugi, H., & Hashido, K. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.06.009 · Cited by 64
MicroRNAs and Alzheimer′s Disease Mouse Models: Current Insights and Future Research Avenues
Delay, C., & Hébert, S. S. (2011) · International Journal of Alzheimer s Disease · doi:10.4061/2011/894938 · Cited by 63
Self-citation
MicroRNA Implications across Neurodevelopment and Neuropathology
Martino, S., di Girolamo, I., Orlacchio, A., Datti, A., & Orlacchio, A. (2009) · BioMed Research International · doi:10.1155/2009/654346 · Cited by 64
LincRNA-p21 Inhibits Cell Viability and Promotes Cell Apoptosis in Parkinson’s Disease through Activating α -Synuclein Expression
Xu, X., Zhuang, C., Wu, Z., Qiu, H., Feng, H., & Wu, J. (2018) · BioMed Research International · doi:10.1155/2018/8181374 · Cited by 61
Decoding the non-coding RNAs in Alzheimer’s disease
Schönrock, N., & Götz, J. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1125-z · Cited by 61
Correcting abnormalities in miR‐124/PTPN1 signaling rescues tau pathology in Alzheimer’s disease
Hou, T., Zhou, Y., Zhu, L., Wang, X., Pang, P., Wang, D., Liuyang, Z., Man, H., Lu, Y., Zhu, L., et al. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.14961 · Cited by 60
Micro RNA association with synucleinopathy conversion in rapid eye movement behavior disorder
Fernández‐Santiago, R., Iranzo, Á., Gaig, C., Serradell, M., Fernández, M., TOLOSA, E. S., Santamaría, J., & Ezquerra, M. (2015) · Annals of Neurology · doi:10.1002/ana.24384 · Cited by 60
Micromanagement of Immune System: Role of miRNAs in Helminthic Infections
Arora, N., Tripathi, S., Singh, A. K., Mondal, P., Mishra, A., & Prasad, A. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00586 · Cited by 60
HOCTAR database: A unique resource for microRNA target prediction
Gennarino, V. A., Sardiello, M., Mutarelli, M., Dharmalingam, G., Maselli, V., Lago, G., & Banfi, S. (2011) · Gene · doi:10.1016/j.gene.2011.03.005 · Cited by 57
Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration
Cheng, S., Hou, J., Zhang, C., Xu, C., Wang, L., Zou, X., Yu, H., Shi, Y. S., Yin, Z., & Chen, G. (2015) · Scientific Reports · doi:10.1038/srep10535 · Cited by 59
Biological pathways to adaptability – interactions between genome, epigenome, nervous system and environment for adaptive behavior
Wolf, C., & Linden, D. E. J. (2011) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2011.00752.x · Cited by 59
Pathophysiology of translational regulation by microRNAs in multiple sclerosis
Junker, A. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.03.052 · Cited by 56
Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice
Abo-ouf, H., Hooper, A. W. M., White, E. J., van Rensburg, H. J. J., Trigatti, B. L., & Igdoura, S. A. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt250 · Cited by 56
Micro-RNAs and Their Roles in Eye Disorders
Raghunath, A., & Perumal, E. (2015) · Ophthalmic Research · doi:10.1159/000371853 · Cited by 55
Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases
Li, D., Li, Y., Li, Y., Zhu, X., Du, X., Zhou, M., Li, W., & Deng, H. (2018) · Chinese Medical Journal · doi:10.4103/0366-6999.240817 · Cited by 55
High-Resolution Northern Blot for a Reliable Analysis of MicroRNAs and Their Precursors
Kościańska, E., Staręga‐Rosłan, J., Czubala, K., & Krzyżosiak, W. J. (2011) · The Scientific World JOURNAL · doi:10.1100/tsw.2011.11 · Cited by 53
MicroRNAs as new players in the pain game
Niederberger, E., Kynast, K. L., Lötsch, J., & Geißlinger, G. (2011) · Pain · doi:10.1016/j.pain.2011.01.042 · Cited by 53
Specific sequence determinants of miR-15/107 microRNA gene group targets
Nelson, P. T., Wang, W.-X., Mao, G., Wilfred, B. R., Xie, K., Jennings, M. H., Gao, Z., & Wang, X. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr532 · Cited by 53
Systems Approach to Neurodegenerative Disease Biomarker Discovery
Lausted, C. G., Lee, I., Zhou, Y. F., Qin, S., Sung, J., Price, N. D., Hood, L., & Wang, K. (2013) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-011613-135928 · Cited by 52
Differential microRNA expression analyses across two brain regions in Alzheimer’s disease
Dobricic, V., Schilling, M., Schulz, J., Zhu, L.-S., Zhou, C.-W., Fuß, J., Franzenburg, S., Zhu, L.-Q., Parkkinen, L., Lill, C. M., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02108-4 · Cited by 48
The Path to microRNA Therapeutics in Psychiatric and Neurodegenerative Disorders
Chan, A. W. S., & Kocerha, J. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00082 · Cited by 54
An overview of circulating cell-free microRNAs as putative biomarkers in Alzheimer's and Parkinson's Diseases
Batistela, M. S., Josviak, N. D., Sulzbach, C. D., & de Souza, R. L. R. (2016) · International Journal of Neuroscience · doi:10.1080/00207454.2016.1209754 · Cited by 53
MoS2 quantum dots modified with a labeled molecular beacon as a ratiometric fluorescent gene probe for FRET based detection and imaging of microRNA
Yu, X., Hu, L., Zhang, F., Wang, M., Xia, Z., & Wei, W. (2018) · Microchimica Acta · doi:10.1007/s00604-018-2773-y · Cited by 52
MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate
Zhang, L., Li, Y., Zeng, H., Wei, J., Wan, Y., Chen, J., & Xu, S. (2010) · Journal of Applied Toxicology · doi:10.1002/jat.1583 · Cited by 53
A Functional Polymorphism in the Promoter Region of MicroRNA-146a Is Associated with the Risk of Alzheimer Disease and the Rate of Cognitive Decline in Patients
Cui, L., Li, Y., Ma, G., Wang, Y., Cai, Y., Liu, S., Chen, Y.-Y., Li, J., Xie, Y., Liu, G., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089019 · Cited by 56
MicroRNAs as Potential Circulating Biomarkers for Amyotrophic Lateral Sclerosis
Cloutier, F., Marrero, A., O’Connell, C. M., & Morin, P. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0471-8 · Cited by 52
The emerging roles of MicroRNAs in autism spectrum disorders
Fregeac, J., Colleaux, L., & Nguyen, L. S. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.018 · Cited by 52
A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues
Wang, Z., Li, D., Tian, X., & Zhang, C. (2021) · Chemical Science · doi:10.1039/d1sc01865e · Cited by 49
Chronological Changes in MicroRNA Expression in the Developing Human Brain
Moreau, M., Bruse, S., Jörnsten, R. J., Liu, Y., & Brzustowicz, L. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060480 · Cited by 48
microRNA-944 overexpression is a biomarker for poor prognosis of advanced cervical cancer
Park, S., Kim, J., Eom, K., Oh, S., Kim, S., Kim, G., Ahn, S., Park, K. H., Chung, D., & Lee, H. (2019) · BMC Cancer · doi:10.1186/s12885-019-5620-6 · Cited by 49
Epigenetics: Recent Advances and Its Role in the Treatment of Alzheimer's Disease
Xiao, X., Liu, X., & Jiao, B. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.538301 · Cited by 53
An enzyme-linked assay for the rapid quantification of microRNAs based on the viral suppressor of RNA silencing protein p19
Nasheri, N., Cheng, J. Y., Singaravelu, R., Wu, P., McDermott, M. T., & Pezacki, J. P. (2011) · Analytical Biochemistry · doi:10.1016/j.ab.2011.01.030 · Cited by 50
MicroRNAs in Neurotoxicity
Kaur, P., Armugam, A., & Jeyaseelan, K. (2012) · Journal of Toxicology · doi:10.1155/2012/870150 · Cited by 48
Advances with microRNAs in Parkinson’s disease research
Yuan, W., Ma, L., Wei, L. L., Wu, F., Hu, Z., & Liu, Z. (2013) · Drug Design Development and Therapy · doi:10.2147/dddt.s48500 · Cited by 51

Authors: Hébert, S. S., & De Strooper, B.
Affiliations: Vlaams Instituut voor Biotechnologie (BE)
ORCID: Hébert, Sébastien S.
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 2009-04
Volume: 32
Issue: 4
Pages: 199-206
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/j.tins.2008.12.003
OpenAlex: W2041945875
Cited by: 452
References: 94
Citations by year: 2026: 11 · 2025: 9 · 2024: 10 · 2023: 16 · 2022: 18 · 2021: 17 · 2020: 26 · 2019: 26 · 2018: 26 · 2017: 19 · 2016: 37 · 2015: 38 · 2014: 26 · 2013: 39 · 2012: 33
FWCI: 2.82
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Lirias (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords: microRNA, neurodegenerative diseases, microRNA dysregulation, post-transcriptional regulation, neuronal development, neurite outgrowth, synaptogenesis, familial neurodegenerative disease
MeSH terms: Animals, Humans, Models, Biological, Neurodegenerative Diseases, MicroRNAs, Gene Regulatory Networks

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Alterations of the microRNA network cause neurodegenerative disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks