Alzheimer's disease, metal ions and metal homeostatic therapy

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864

Alzheimer's disease: the amyloid cascade hypothesis

Hardy, J. A., & Higgins, G. A. (1992) · Science · doi:10.1126/science.1566067 · Cited by 7,484

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., & LaFerla, F. M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00434-3 · Cited by 4,126

The Free Radical Theory of Aging Matures

BECKMAN, K. B., & AMES, B. N. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.2.547 · Cited by 3,879

Copper, iron and zinc in Alzheimer's disease senile plaques

Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., & Markesbery, W. R. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00092-6 · Cited by 2,120

Intracellular amyloid-β in Alzheimer's disease

LaFerla, F. M., Green, K. N., & Oddo, S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2168 · Cited by 1,942

The neurobiology of zinc in health and disease

Frederickson, C. J., Koh, J., & Bush, A. I. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1671 · Cited by 1,841

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

Cleary, J. P., Walsh, D. M., Hofmeister, J. J., Shankar, G. M., Kuskowski, M. A., Selkoe, D. J., & Ashe, K. H. (2004) · Nature Neuroscience · doi:10.1038/nn1372 · Cited by 1,722

The Dialysis Encephalopathy Syndrome

Alfrey, A. C., LeGendre, G. R., & Kaehny, W. D. (1976) · New England Journal of Medicine · doi:10.1056/nejm197601222940402 · Cited by 1,628

Copper chelation and exogenous copper affect circadian clock phase resetting in the suprachiasmatic nucleus in vitro

Yamada, Y., & Prosser, R. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.10.033 · Cited by 16

Chelation-induced diradical formation as an approach to modulation of the amyloid-β aggregation pathway

Porter, M. R., Kochi, A., Karty, J. A., Lim, M. H., & Zaleski, J. M. (2014) · Chemical Science · doi:10.1039/c4sc01979b · Cited by 16

New amyloid beta-disaggregating agents: synthesis, pharmacological evaluation, crystal structure and molecular docking of N -(4-((7-chloroquinolin-4-yl)oxy)-3-ethoxybenzyl)amines

Umar, T., Shalini, S., Raza, M. K., Gusain, S., Kumar, J., Ahmed, W., Tiwari, M., & Hoda, N. (2018) · MedChemComm · doi:10.1039/c8md00312b · Cited by 16

Design and synthesis of thymine modified phthalocyanine for Aβ protofibrils photodegradation and Aβ peptide aggregation inhibition

Zhan, Q., Shi, X., Wang, T., Hu, J., Zhou, J., Zhou, L., & Wei, S. (2018) · Talanta · doi:10.1016/j.talanta.2018.08.037 · Cited by 16

A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium

Angelantonio, S. D., Murana, E., Cocco, S., Scala, F., Bertollini, C., Molinari, M., Lauro, C., Bregestovski, P. D., Limatola, C., & Ragozzino, D. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.437 · Cited by 16

Rôles biologiques des éléments traces dans le cerveau – exemples du Zn et du Fe

Bohic, S., Ghersi‐Egea, J., Gibon, J., Paoletti, P., Arnaud, J., Hunot, S., Boom, A., & Bouron, A. (2010) · Revue Neurologique · doi:10.1016/j.neurol.2010.07.035 · Cited by 16

Considering the Vascular Hypothesis of Alzheimer’s Disease: Effect of Copper Associated Amyloid on Red Blood Cells

Lucas, H. R., & Rifkind, J. M. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-4989-8_19 · Cited by 16

Neuroprotective effect ofBryophyllum pinnatumflavonoids against aluminum chloride-induced neurotoxicity in rats

Ogidigo, J. O., Anosike, C. A., Joshua, P. E., Ibeji, C. U., Nwanguma, B. C., & Nwodo, O. F. C. (2021) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2021.1995557 · Cited by 17

Corrosion behavior and incorporation mechanism of Y2O3-TiO2 composite coatings fabricated on TC4 titanium alloy by plasma electrolytic oxidation

Li, H., & Wang, Z. (2024) · Chemical Physics Letters · doi:10.1016/j.cplett.2024.141170 · Cited by 15

Effect of Aluminum, Iron, and Zinc Ions on the Assembly of Microtubules from Brain Microtubule Proteins

Shevtsov, P. N., Shevtsova, E. F., & Burbaeva, G. S. (2016) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-016-3436-9 · Cited by 15

Time-Evolved SERS Signatures of DEP-Trapped Aβ and Zn2+Aβ Peptides Revealed by a Sub-10 nm Electrode Nanogap

Vu, K. H. P., Lee, M., Blankenburg, G. H., Chang, Y., Chu, M.-L., Erbe, A., Lesser‐Rojas, L., Chen, Y., & Chou, C. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c01521 · Cited by 15

Physiological cholesterol concentration is a neuroprotective factor against β-amyloid and β-amyloid–metal complexes toxicity

Granzotto, A., Suwalsky, M., & Zatta, P. F. (2011) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2011.05.013 · Cited by 14

Direct bioactive ceramics coating via reactive Growing Integration Layer method on α-Ti-alloy

Huang, C.-H., Chen, R.-S., & Yoshimura, M. (2017) · Materials Science and Engineering C · doi:10.1016/j.msec.2017.03.182 · Cited by 14

N-doped carbon dots modified with the epithelial cell adhesion molecule antibody as an imaging agent for HepG2 cells using their ultra-sensitive response to Al 3+

Li, Z., Wang, T., Gu, L., Wang, H., Zhao, Y., Lu, S., Zhao, W., & Sun, T. (2020) · Nanotechnology · doi:10.1088/1361-6528/abb0b5 · Cited by 13

Zinc homeostatic proteins in the CNS are regulated by crosstalk between extracellular and intracellular zinc

Karol, N., Brodski, C., Bibi, Y., Kaisman‐Elbaz, T., Forberg, M., Hershfinkel, M., Sekler, I., & Silverman, W. F. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22168 · Cited by 13

Insight into inhibition of the human amyloid beta protein precursor (APP: PDB ID 3UMI) using (E)-N-(pyridin-2-ylmethylene)arylamine (L R ) models: structure elucidation of a family of ZnX 2 -L R complexes

Baul, T. S. B., Kundu, S., Singh, P., Shaveta, S., & da Silva, M. F. C. G. (2014) · Dalton Transactions · doi:10.1039/c4dt03151b · Cited by 13

Fasting, a Potential Intervention in Alzheimer's Disease

Zeng, Z., Zhang, H., Wang, X., Shen, J., & Chen, D. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2303050 · Cited by 12

Cellular activity of the cytosolic selenoprotein thioredoxin reductase 1 (TXNRD1) is modulated by copper and zinc levels in the cell culture medium

Scholzen, K., & Arnér, E. S. J. (2025) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2025.127624 · Cited by 12

Metalloneurochemistry and the Pierian Spring: ‘Shallow Draughts Intoxicate the Brain’

Goldberg, J. M., Loas, A., & Lippard, S. J. (2016) · Israel Journal of Chemistry · doi:10.1002/ijch.201600034 · Cited by 12

Highly selective, sensitive and biocompatible rhodamine-based isomers for Al3+ detection: A comparative study

Ghosh, S., Mahato, S., Dutta, T., Ahamed, Z., Ghosh, P., & Roy, P. S. (2023) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2023.123455 · Cited by 12

Memory restorative ability of clioquinol in copper–cholesterol-induced experimental dementia in mice

Mehra, R., Sodhi, R. K., & Aggarwal, N. (2015) · Pharmaceutical Biology · doi:10.3109/13880209.2014.974061 · Cited by 12

Beta-amyloid toxicity increases with hydrophobicity in the presence of metal ions

Granzotto, A., Bolognin, S., Ščančar, J., Milačić, R., & Zatta, P. F. (2011) · Monatshefte für Chemie - Chemical Monthly · doi:10.1007/s00706-011-0470-1 · Cited by 11

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

Keskitalo, S., Farkas, M., Hanenberg, M., Szodorai, A., Kulic, L., Semmler, A., Weller, M., Nitsch, R. M., & Linnebank, M. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00237 · Cited by 13

BODIPY in Alzheimer's disease diagnostics: A review

Abramchuk, D., Voskresenskaya, A. S., Kuzmichev, I., Erofeev, A. S., Gorelkin, P. V., Abakumov, M. A., Beloglazkina, E. K., & Krasnovskaya, O. O. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.116682 · Cited by 11

Metal ions and protons compete for ligand atoms in disordered peptides: Examples from computer simulations of copper binding to the prion tandem repeat

Furlan, S., & Penna, G. L. (2012) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2012.03.036 · Cited by 11

The Role of Zinc in Mood Disorders

Piao, M., Cong, X., Ying, L., Feng, C., & Ge, P. (2017) · Neuropsychiatry · doi:10.4172/neuropsychiatry.1000225 · Cited by 14

Metal-dependent interactions of metallothionein-3 β-domain with amyloid-β peptide and related physiological implications

Jiang, Z., Shen, B., & Xiang, J. (2019) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2019.110693 · Cited by 11

Histidine Residues Are Responsible for Bidirectional Effects of Zinc on Acid-Sensing Ion Channel 1a/3 Heteromeric Channels

Jiang, Q., Peterson, A. M., Chu, Y., Yao, X., Zha, X., & Chu, X. (2020) · Biomolecules · doi:10.3390/biom10091264 · Cited by 11

Tackling Alzheimer’s Disease with Existing Drugs: A Promising Strategy for Bypassing Obstacles

Rampa, A., Gobbi, S., Belluti, F., & Bisi, A. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200831140745 · Cited by 11

Inhibition of Alzheimer's Aβ1‐42 Fibrillogenesis and Removal of Copper Ions by Polypeptides Modified Gold Nanoparticles

Zhou, B., Sheng, X., Xie, H., Zhou, S., Zhong, M., & Liu, A. (2022) · Chemistry & Biodiversity · doi:10.1002/cbdv.202200342 · Cited by 11

Ethanol Reduces Zincosome Formation in Cultured Astrocytes

Ballestín, R., Molowny, A., Marin, M. P., Esteban-Pretel, G., Romero, A. M., López‐García, C., Renau‐Piqueras, J., & Ponsoda, X. (2010) · Alcohol and Alcoholism · doi:10.1093/alcalc/agq079 · Cited by 11

Potential role of herbal plants and beta sitosterol as a bioactive constituent in circumventing Alzheimer’s Disease

Mishra, A., Das, S., & Kumari, S. (2023) · Plant Science Today · doi:10.14719/pst.2420 · Cited by 10

A dynamic regulatory switch for phase separation of FUS protein: Zinc ions and zinc finger domain

Chen, Y., Pei, X., Chen, L., & Chen, L. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.149862 · Cited by 10

Discovery of powerful multifaceted antioxidant for combating oxidative stress associated with neurodegenerative disorders

Khan, J., Gharai, P. K., Garg, S., Gupta, S., Arshi, M. U., Mallesh, R., & Ghosh, S. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.04.024 · Cited by 10

Near‐Infrared Fluorescent Probe for the Early Diagnosis of Alzheimer's Disease

Liu, Y., Sun, Y., Zhao, P., Liu, Z., Wang, Y., Wang, Y., Zhao, R., Wang, C., & Wang, S. (2025) · Medicinal Research Reviews · doi:10.1002/med.70000 · Cited by 12

Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors

de Santana, Q. L. O., Evangelista, T. C. S., Imhof, P., Ferreira, S. B., Fernández‐Bolaños, J. G., Sydnes, M. O., López, Ó., & Lindbäck, E. (2021) · Organic & Biomolecular Chemistry · doi:10.1039/d0ob02588g · Cited by 10

A Novel Aluminum (III)-selective PVC Membrane Electrode Based on a Schiff Base Complex of bis(5-sulphonate salicylaldehyde) 2,3-diaminobenzene

Yao, H., Wang, S., Ma, X., Ren, L., & Yan, F. (2014) · International Journal of Electrochemical Science · doi:10.1016/s1452-3981(23)07918-x · Cited by 10

Stoichiometry of Heavy Metal Binding to Peptides Involved in Alzheimer’s Disease: Mass Spectrometric Evidence

Jureschi, M., Lupăescu, A.-V., Ion, L., Petre, B. A., & Drochioiu, G. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-15950-4_23 · Cited by 10

Preparation, anticholinesterase activity, and docking study of new 2-butenediamide and oxalamide derivatives

Yerdelen, K. Ö., Koca, M., Kasap, Z., & Anıl, B. (2014) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2014.959947 · Cited by 10

Dietary High Cholesterol and Trace Metals in the Drinking Water Increase Levels of ABCA1 in the Rabbit Hippocampus and Temporal Cortex

Schreurs, B. G., & Sparks, D. L. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150601 · Cited by 10

Exploring the mechanisms of chrysin in combating Alzheimer's disease: therapeutic perspectives

Singh, T. G., SHARMA, A. K., & Devi, S. (2024) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2024.162341 · Cited by 9

Cu and Zn Interactions with Peptides Revealed by High-Resolution Mass Spectrometry

Iavorschi, M., Lupăescu, A.-V., Darie‐Ion, L., Indeykina, M. I., Hitruc, E. G., & Petre, B. A. (2022) · Pharmaceuticals · doi:10.3390/ph15091096 · Cited by 9

The New Role for an Old Kinase: Protein Kinase CK2 Regulates Metal Ion Transport

Johnson, A. J., & Wu, M. J. (2016) · Pharmaceuticals · doi:10.3390/ph9040080 · Cited by 9

Medicinal Chemistry of Hybrids for Neurodegenerative Diseases

Uliassi, E., Prati, F., Bongarzone, S., & Bolognesi, M. L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-101011-2.00010-6 · Cited by 10

The Chinese herbal formula Fuzheng Quxie Decoction attenuates cognitive impairment and protects cerebrovascular function in SAMP8 mice

Wang, F., Feng, J., Yang, Y., Liu, J., Liu, M., Wang, Z., Pei, H., Wei, Y., & Li, H. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s175484 · Cited by 8

Reviewing Biochemical Implications of Normal and Mutated Huntingtin in Huntington’s Disease

Tellone, E., Galtieri, A., & Ficarra, S. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190621101909 · Cited by 9

Metallothionein Zn 2+ - and Cu 2+ -clusters from first-principles calculations

Greisen, P. J., Jespersen, J. B., & Kepp, K. P. (2011) · Dalton Transactions · doi:10.1039/c1dt11785h · Cited by 9

Combination of Aβ clearance and neurotrophic factors as a potential treatment for Alzheimer’s disease

Lin, L.-F., Liao, M., Xue, X., Zhang, W., Yan, L., Cai, L., Zhou, X., Zhou, X., & Luo, H. (2012) · Neuroscience Bulletin · doi:10.1007/s12264-012-1287-6 · Cited by 10

Multi-Target-Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery

Patil, V. M., Masand, N., Gautam, V., Kaushik, S., & Wu, D. H. (2023) · Springer eBooks · doi:10.1007/978-981-99-2657-2_13 · Cited by 9

Evaluating the Neuroprotective Potential of Caffeinated Coffee in the Context of Aluminum-Induced Neurotoxicity: Insights from a PC12 Cell Culture Model

Rodak, K., Bęben, D., Birska, M., Siwiela, O., Kokot, I., Moreira, H., Radajewska, A., Szyjka, A., & Kratz, E. M. (2024) · Antioxidants · doi:10.3390/antiox13030342 · Cited by 8

Copper in the suprachiasmatic circadian clock: A possible link between multiple circadian oscillators

Yamada, Y., & Prosser, R. A. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14181 · Cited by 8

Estimation of calcium, magnesium, cadmium, and lead in biological samples from paralyzed quality control and production steel mill workers

Afridi, H. I., Talpur, F. N., Kazi, T. G., Kazi, N. G., Arain, S. S., & Shah, F. (2015) · Environmental Monitoring and Assessment · doi:10.1007/s10661-015-4517-3 · Cited by 8

Effect of Nanoparticles on Modified Screen Printed Inhibition Superoxide Dismutase Electrodes for Aluminum

Barquero-Quirós, M., & Arcos‐Martínez, M. J. (2016) · Sensors · doi:10.3390/s16101588 · Cited by 7

A Comprehensive Review of Herbal Medicines for the Treatment of Alzheimer's Disease

Shadab, S., Rao, G. K., Paliwal, D., Yadav, D., Alam, A., Singh, A., & Sultana, M. J. (2023) · Current Traditional Medicine · doi:10.2174/2215083810666230608151821 · Cited by 7

Arylphosphonate‐Tethered Porphyrins: Fluorescence Silencing Speaks a Metal Language in Living Enterocytes**

Keil, C., Klein, J., Schmitt, F., Zorlu, Y., Haase, H., & Yücesan, G. (2021) · ChemBioChem · doi:10.1002/cbic.202100031 · Cited by 6

Predicted intake of trace elements and minerals via household drinking water by 6-year-old children from Krakow, Poland. Part 5: Zinc

Bartoń, H. (2010) · Food Additives & Contaminants Part A · doi:10.1080/02652030903214355 · Cited by 7

Microwave-Assisted Synthesis, Molecular Docking, and Cholinesterase Inhibitory Activities of New Ethanediamide and 2-Butenediamide Analogues

Koca, M., Yerdelen, K. Ö., Anıl, B., & Kasap, Z. (2015) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.c14-00754 · Cited by 7

The effect of Zn2+onPelodiscus sinensiscreatine kinase: unfolding and aggregation studies

Wang, S., Lee, J., Wang, W., Si, Y.-X., Li, C., Kim, T., Yang, J., Yin, S., & Qian, G.-Y. (2012) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2012.706074 · Cited by 7

Metallodrugs in Medicine

Yousuf, I., & Bashir, M. (2020) · doi:10.1002/9781119640868.ch1 · Cited by 7

Metals in medicine: unlocking new avenues for neurodegenerative disease treatment

Tan, K. T., Cheong, K. W., Wong, L. C., Bertrand, H. C., Karim, N. H. A., Chong, Y. K., & Low, M. L. (2025) · Frontiers in Chemical Biology · doi:10.3389/fchbi.2025.1696058 · Cited by 6

A commentary on studies of brain iron accumulation during ageing

Hackett, M. (2024) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-024-02060-2 · Cited by 3

Using a portable total reflection X‐ray fluorescence system for a multielement analysis of Swiss mice brains with experimental Alzheimer's disease induced by β‐amyloid oligomers

Almeida, D. S., Brígido, M. M., Anjos, M. J., Ferreira, S. T., de Souza, A. S., & Lopes, R. T. (2019) · X-Ray Spectrometry · doi:10.1002/xrs.3044 · Cited by 7

Investigation of Some Metabolic Enzyme Inhibition Properties of Novel Chalcone‐Cu Complexes

Ebiri, R., Turgut, M., Anıl, D. A., Demir, Y., Sağlamtaş, R., Alagöz, M. A., Algül, Ö., & Burmaoğlu, S. (2024) · ChemistrySelect · doi:10.1002/slct.202401093 · Cited by 5

Cardiotoxicity and ROS Protection Assessment of three Structure‐Related N‐Acylhydrazones with Potential for the Treatment of Neurodegenerative Diseases

Santa-Helena, E., Falco, A. D., Cukierman, D. S., Gioda, A., Gioda, C. R., & Rey, N. A. (2024) · Chemistry & Biodiversity · doi:10.1002/cbdv.202400356 · Cited by 5

Investigating Anion Effects on Metal Ion Binding Interactions With Amyloid β Peptide by Ion Mobility Mass Spectrometry

Zhang, J., Phetsanthad, A., & Li, L. (2024) · Journal of Mass Spectrometry · doi:10.1002/jms.5090 · Cited by 5

Self-assembly of Cu(ii) with amyloid β19–20 peptide: relevant to Alzheimer's disease

Shen, X., Deng, X., & Pang, Y. (2014) · RSC Advances · doi:10.1039/c4ra02758b · Cited by 5

Nutrient‐sensing amyloid metastasis

Lima, L. M. T. R., & Sisnande, T. (2022) · BioFactors · doi:10.1002/biof.1825 · Cited by 5

Effects of applied voltage on the microstructure and properties of hydroxyapatite bioceramic coatings formed on Ti7Cu5Sn titanium alloy by micro-arc oxidation

Tsao, L. C. (2018) · Corrosion Engineering Science and Technology The International Journal of Corrosion Processes and Corrosion Control · doi:10.1080/1478422x.2018.1513619 · Cited by 5

A smart adaptable metal sequestering peptide conjugate to modulate Aβ fibrillar aggregation

Mondal, T., Kalita, S., Dutta, R., & Mandal, B. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb01093k · Cited by 4

Aluminum chloride in Alzheimer's disease: A dual focus on molecular mechanisms and rat experimental models

Khattab, N. A., El-Kadem, A. H., Goda, A. E., El‐Mahdy, N. A., & El‐Shitany, N. A. (2026) · Experimental Neurology · doi:10.1016/j.expneurol.2026.115814 · Cited by 4

An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease

Shome, A., Jha, K. T., Chahat, Chawla, V., & Chawla, P. A. (2024) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/0118715273315191241002115155 · Cited by 4

The role of ligand covalency in the selective activation of metalloenediynes for Bergman cyclization

Porter, M. R., & Zaleski, J. M. (2015) · Polyhedron · doi:10.1016/j.poly.2015.10.041 · Cited by 4

Network Approaches to the Understanding of Alzheimer’s Disease: From Model Organisms to Humans

Yerbury, J. J., Bean, D. M., & Favrin, G. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2627-5_27 · Cited by 4

Metals and Autophagy in Neurotoxicity

Su, P., Aschner, M., Chen, J., & Luo, W. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804562-6.00019-1 · Cited by 4

Phytopharmaceuticals In The Therapy Of Younger Alzheimer Patients

Kastenholz, B. (2011) · Cited by 4

Isophthaloyl-Based Selective Fluorescence Receptor for Zn (II) Ion in Semi-Aqueous Medium

Khadke, N. B., Patil, A., Patil, D. Y., & Borhade, A. V. (2019) · Journal of Fluorescence · doi:10.1007/s10895-019-02385-1 · Cited by 4

Effect of plain and fortified amla fruit powder on aluminum-induced Alzheimer's Disease in Wistar Rats

Vishala, T. C., Pitchaiah, G., Pravadha, D., & Annapurna, A. (2019) · Pharmacognosy Research · doi:10.4103/pr.pr_17_17 · Cited by 4

The Influence of Ca2+ and Zn2+ on the Amyloid Fibril Formation by β-Casein

Wang, J., Liu, J., Du, G., An, Y., Zhao, C., & Zeng, B. (2020) · Protein and Peptide Letters · doi:10.2174/0929866527666200318143533 · Cited by 4

C-Reactive Protein and Neurodegenerative Diseases

Cardoso, I. L., & Leal, M. F. C. (2020) · Springer eBooks · doi:10.1007/978-981-15-6787-2_2 · Cited by 4

Probing the role of metal cations on the aggregation behavior of amyloid β-peptide at a single molecule level by AFM

Xie, Y., Wang, J., & Liu, C. (2016) · Journal of Nanoparticle Research · doi:10.1007/s11051-016-3600-1 · Cited by 4

Lung nodules after whole lung radiation.

Cohen, M. D., Mirkin, D. L., Provisor, A. J., Hornback, N. B., Smith, J. A., & Slabaugh, R. D. (1983) · PubMed · Cited by 4

Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer’s Disease

Travers--Lesage, V., Since, M., Wang, A., Davis, A., Fayolle, D., Bernay, B., Modeste, F., Nachon, F., Brazzolotto, X., Crouzier, L., et al. (2026) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6c00170 · Cited by 3

Progress in the development of anti-amyloid drugs for treatment of Alzheimer’s disease

Shitaka, Y., Mitani, Y., Nagakura, A., Miyake, A., & Matsuoka, N. (2010) · Folia Pharmacologica Japonica · doi:10.1254/fpj.136.15 · Cited by 3

Detection of ferric ions in a gram-positive bacterial cell:Staphylococcus aureus

Manandhar, E., Johnson, A., Watson, W. M., Dickerson, S. D., Sahukhal, G. S., Elasri, M. O., Fronczek, F. R., Cragg, P. J., & Wallace, K. J. (2020) · Journal of Coordination Chemistry · doi:10.1080/00958972.2020.1868042 · Cited by 3

Brain tissue electrical conductivity as a promising biomarker for dementia assessment using MRI

Chu, J., Yao, J., Li, Z., Li, J., Zhang, Y., Liu, C., He, H., Li, B., & Wei, H. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70270 · Cited by 4

Effect of Zinc and DHA on Expression Levels and Post-Translational Modifications of Histones H3 and H4 in Human Neuronal Cells

Sadli, N., Ahmed, N., Leigh, M., Sinclair, A. J., Colin, J., & Suphioglu, C. (2011) · InTech eBooks · doi:10.5772/28135 · Cited by 2

Biosensor for Aluminum(III) Based on α-Chymotrypsin Inhibition using a Disposable Screen-Printed Carbon Electrode and Acetyl-Tyrosine Ethyl Ester as Substrate

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Ruthenium Complexes of Phenylbenzothiazole‐Quinoline based Ligands for Selective α‐Olefination of Methylazaarenes

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Outdoor Air Pollution, Perivascular Space Morphology, and Cognition in Preadolescence

Morrel, J., Sukumaran, K., Torgerson, C. M., Rosario, M. A., Lan, H., Schwartz, J. D., Chen, J., Choupan, J., & Herting, M. M. (2026) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2026.100790 · Cited by 3

Pyranotacrines as prospective multi-target compounds against Alzheimer's disease

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Tris[2-(1,3-thiazol-2-yl-κN)-1H-benzimidazole-κN3]zinc(II) dinitrate ethanol hemisolvate monohydrate at 100 K

de Oliveira, F. L., Huber, P. C., Almeida, W. P., Sabino, J. R., & Aparício, R. (2013) · Acta Crystallographica Section C Crystal Structure Communications · doi:10.1107/s0108270112051372 · Cited by 2

Multielement concentration analysis of Swiss mice brains on experimental model of Alzheimer's disease induced by β ‐amyloid oligomers

Almeida, D. S., dos Santos, R. S., Anjos, M. J., Ferreira, S. T., de Souza, A. S., & Lopes, R. T. (2017) · X-Ray Spectrometry · doi:10.1002/xrs.2753 · Cited by 2

(Gd3+) Complexation with oligopeptide (SFVG) and amyloid peptide (Aβ13–23) in aqueous solution by NMR spectroscopy

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Effect of Sempervivum tectorum Extract on Some Biomarkers of Reproductive Function and Levels of Some Trace Elements in Male Rats Exposed to Aluminum

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Neurodegeneration in Neural Trauma, Neurodegenerative Diseases, and Neuropsychiatric Disorders

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Metal ions and beta amyloid: conformational modifications and biological aspects

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Alzheimer’s Dementia and Lifestyle: Towards a Primary Prevention

Walach, H., & Loef, M. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6852-3_12 · Cited by 2

Metal ions, protein folding, and conformational states: an introduction

Gomes, C. M. (2010) · Cited by 2

First studies on the interactions of the C-terminal cystatin C fragment 85–94 with Cu(II) ions

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Role of Amyloid-β–Metal Interactions In Alzheimer‘s Disease

Duce, J. A., Bush, A. I., & Adlard, P. A. (2011) · Future Neurology · doi:10.2217/fnl.11.43 · Cited by 20

Role of metals in Alzheimer’s disease

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Metals and Alzheimer′s Disease

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Dysregulated metal homeostasis in Alzheimer’s disease: From pathological modulators to therapeutic targets

Yang, J., Lou, F., Sun, W., Li, M., Su, L., Wang, Y., 李平安, & Su, J. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.109690

Rebalancing metal dyshomeostasis for Alzheimer’s disease therapy

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