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Cited by 246

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Lymphocytes and ischemia-reperfusion injury

Open access
Linfert, Douglas, Chowdhry, Tayseer, Rabb, Hamid·2009·Transplantation Reviews

Abstract

Ischemia reperfusion injury (IRI) is a common and important clinical problem in many different organ systems, including kidney, brain, heart, liver, lung, and intestine. IRI occurs during all deceased donor organ transplants. IRI is a highly complex cascade of events that includes interactions between vascular endothelium, interstitial compartments, circulating cells, and numerous biochemical entities. It is well established that the innate immune system, such as complement, neutrophils, cytokines, chemokines, and macrophages participate in IRI. Recent data demonstrates an important role for lymphocytes, particularly T cells but also B cells in IRI. Lymphocytes not only participate in augmenting injury responses after IRI, but could also be playing a protective role depending on the cell type and stage of injury. Furthermore, lymphocytes appear to be participating in the healing response from IRI. These new data open the possibility for lymphocyte targeted therapeutics to improve the short and long term outcomes from IRI.

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Crossref · 10.1016/j.trre.2008.08.003

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Metadata

Authors
Linfert, D., Chowdhry, T., & Rabb, H.
Venue
Transplantation Reviews
Publisher
Elsevier BV
Published
2009-01
Volume
23
Issue
1
Pages
1-10
ISSN
0955-470X (ISSN-L)
OpenAlex
W2020371427
Cited by
246
References
2
FWCI
14.55
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Lymphocytes and ischemia-reperfusion injury. https://app.cochat.ai/papers/10.1016/j.trre.2008.08.003
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Linfert, D., Chowdhry, T., & Rabb, H. (2009). Lymphocytes and ischemia-reperfusion injury. Transplantation Reviews. https://doi.org/10.1016/j.trre.2008.08.003

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