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Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: Potential use in companion animals
Abstract
Endocannabinoids have analgesic/anti-inflammatory properties. The biology of endocannabinoids, their receptors, signalling mechanisms and role in the regulation of physiological processes have been extensively reviewed. This review focuses on the role of palmitoylethanolamide (PEA), an endogenous fatty acid amide analogue of the endocannabinoid anandamide, in tissue protective mechanisms. PEA was first identified almost five decades ago in lipid extracts of various natural products, and its anti-inflammatory and antinociceptive effects were established later. Evidence exists that PEA is synthesised during inflammation and tissue damage and a number of beneficial effects, including the relief of inflammation and pruritus, have been shown to be useful in the control of neurogenic and neuropathic pain. The postulated hypotheses as to the mode of action of PEA include a possible local autacoid-like mediator activity regulating mast-cell activity and putative activation of cannabinoids and vanilloid TRPV1 receptors via "entourage" effects. The large number of scientific investigations into the effects of PEA and PEA-related compounds has given rise to new therapeutic opportunities. In spite of the multitude of therapies currently employed to control inflammation, pain, pruritus and tissue damage, the possibility of using a natural compound, such as PEA to manipulate endogenous protective mechanisms may be considered a beneficial novel therapeutic strategy in veterinary medicine.
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“PEA may indirectly alter levels of endocannabinoids by competing with anandamide and other fatty-acid amides for degradation by FAAH or by suppressing FAAH expression at the transcriptional level.27, 28”
From Cannabinoids as Pharmacotherapies for Neuropathic Pain: From the Bench to the Bedside (2009) · cites this paper as [27]
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1 retracted
Ahluwalia, J., Yaqoob, M., Urbán, L., Bevan, S., & Nagy, I. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01550.x · Cited by 82
RetractedIsolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor
Devane, W. A., Hanuš, L., Breuer, A., Pertwee, R. G., Stevenson, L. A., Griffin, G., Gibson, D., Mandelbaum, A., Etinger, A., & Mechoulam, R. (1992) · Science · doi:10.1126/science.1470919 · Cited by 5,633
Molecular characterization of a peripheral receptor for cannabinoids
Munro, S., Thomas, K. L., & Abu-Shaar, M. (1993) · Nature · doi:10.1038/365061a0 · Cited by 5,092
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
Matsuda, L. A., Lolait, S. J., Brownstein, M. J., Young, A. C., & Bonner, T. I. (1990) · Nature · doi:10.1038/346561a0 · Cited by 5,011
Determination and characterization of a cannabinoid receptor in rat brain
Devane, W. A., Dysarz, F. A., Johnson, M. R., Melvin, L. S., & Howlett, A. C. (1988) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09876-1 · Cited by 2,443
Bonica, J. J. (1954) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195405000-00015 · Cited by 1,467
Control of pain initiation by endogenous cannabinoids
Calignano, A., Rana, G. L., Giuffrida, A., & Piomelli, D. (1998) · Nature · doi:10.1038/28393 · Cited by 1,069
Pathobiology of neuropathic pain
Zimmermann, M. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01303-6 · Cited by 935
Nerve growth factor: from neurotrophin to neurokine
Levi‐Montalcini, R., Skaper, S. D., Toso, R. D., Petrelli, L., & Leon, A. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10058-8 · Cited by 686
Ben‐Shabat, S., Fride, E., Sheskin, T., Tamiri, T., Rhee, M. H., Vogel, Z., Bisogno, T., PETROCELLIS, L. D., Marzo, V. D., & Mechoulam, R. (1998) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00392-6 · Cited by 650
Research works printed but not linked: 1
- Jack, 1996, Aliamides: a new approach to the treatment of inflammation, Drug News and Perspectives, 9, 93
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Carta, G., Murru, E., Banni, S., & Manca, C. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00902 · Cited by 862
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Saturnino, C., Popolo, A., Ramunno, A., Adesso, S., Pecoraro, M., Plutino, M. R., Rizzato, S., Albinati, A., Marzocco, S., Sala, M., et al. (2017) · Molecules · doi:10.3390/molecules22040616 · Cited by 451
Iannotti, F. A., Marzo, V. D., & Petrosino, S. (2016) · Progress in Lipid Research · doi:10.1016/j.plipres.2016.02.002 · Cited by 373
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Ho, W. ‐. V., Barrett, D. A., & Randall, M. D. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.324 · Cited by 259
Maione, S., PETROCELLIS, L. D., de Novellis, V., Moriello, A. S., Petrosino, S., Palazzo, E., Rossi, F., Woodward, D. F., & Marzo, V. D. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707145 · Cited by 200
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BURSTEIN, S. H., & Zurier, R. B. (2009) · The AAPS Journal · doi:10.1208/s12248-009-9084-5 · Cited by 139
Guida, F., Luongo, L., Boccella, S., Giordano, M., Romano, R., Bellini, G., Manzo, I., Furiano, A., Rizzo, A., Imperatore, R., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-00342-1 · Cited by 133
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Impellizzeri, D., Esposito, E., Attley, J., & Cuzzocrea, S. (2014) · Pharmacological Research · doi:10.1016/j.phrs.2014.02.007 · Cited by 126
Guida, F., Luongo, L., Marmo, F., Romano, R., Iannotta, M., Napolitano, F., Belardo, C., Marabese, I., D’Aniello, A., Gregorio, D. D., et al. (2015) · Molecular Brain · doi:10.1186/s13041-015-0139-5 · Cited by 128
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García‐Ovejero, D., Arévalo‐Martín, Á., Petrosino, S., Docagne, F., Hagen, C., Bisogno, T., Watanabe, M., Guaza, C., Marzo, V. D., & Molina‐Holgado, E. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.09.015 · Cited by 128
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Petrosino, S., Cristino, L., Karsak, M., Gaffal, E., Ueda, N., Tüting, T., Bisogno, T., Filippis, D. D., D’Amico, A., Saturnino, C., et al. (2009) · Allergy · doi:10.1111/j.1398-9995.2009.02254.x · Cited by 120
Balvers, M. G. J., Verhoeckx, K. C. M., Bijlsma, S., Rubingh, C. M., Meijerink, J., Wortelboer, H. M., & Witkamp, R. F. (2012) · Metabolomics · doi:10.1007/s11306-012-0421-9 · Cited by 114
Balvers, M. G. J., Verhoeckx, K. C. M., & Witkamp, R. F. (2009) · Journal of Chromatography B · doi:10.1016/j.jchromb.2009.04.010 · Cited by 105
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Matias, I., Gonthier, M., Petrosino, S., Docimo, L., Capasso, R., Hoareau, L., Monteleone, P., Roche, R., Izzo, A. A., & Marzo, V. D. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707424 · Cited by 109
Citraro, R., Russo, E., Scicchitano, F., van Rijn, C. M., Cosco, D., Avagliano, C., Russo, R., D’Agostino, G., Petrosino, S., Guida, F., et al. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.11.017 · Cited by 100
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Scuderi, C., Esposito, G., Blasio, A., Valenza, M., Arietti, P., Steardo, L., Carnuccio, R., Filippis, D. D., Petrosino, S., Iuvone, T., et al. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01267.x · Cited by 100
Starowicz, K., Makuch, W., Korostyński, M., Małek, N., Ślęzak, M., Żychowska, M., Petrosino, S., PETROCELLIS, L. D., Cristino, L., Przewłocka, B., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060040 · Cited by 97
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Cerrato, S., Brazís, P., della Valle, M. F., Miolo, A., & Puigdemont, A. (2009) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2009.06.011 · Cited by 93
Meijerink, J., Plastina, P., Vincken, J., Poland, M., Attya, M., Balvers, M. G. J., Gruppen, H., Gabriele, B., & Witkamp, R. F. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114510005635 · Cited by 92
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Marini, I., Bartolucci, M. L., Bortolotti, F., Gatto, M. R., & Bonetti, G. A. (2012) · PubMed · Cited by 81
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Galiazzo, G., Giancola, F., Stanzani, A., Fracassi, F., Bernardini, C., Forni, M., Pietra, M., & Chiocchetti, R. (2018) · Histochemistry and Cell Biology · doi:10.1007/s00418-018-1684-7 · Cited by 89
Filippis, D. D., Luongo, L., Cipriano, M., Palazzo, E., Cinelli, M. P., de Novellis, V., Maione, S., & Iuvone, T. (2011) · Molecular Pain · doi:10.1186/1744-8069-7-3 · Cited by 76
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Lam, P. M. W., Marczylo, T. H., & Konje, J. C. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4103-z · Cited by 75
Romero, T. R. L., Resende, L. C., Guzzo, L. S., & Duarte, I. D. G. (2013) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3182707859 · Cited by 74
Montecucco, F., Matias, I., Lenglet, S., Petrosino, S., Burger, F., Pelli, G., Braunersreuther, V., Mach, F., Steffens, S., & Marzo, V. D. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.12.040 · Cited by 73
Murillo‐Rodríguez, E., Vázquez, E., Millán‐Aldaco, D., Palomero‐Rivero, M., & Drucker-Colı́n, R. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.01.076 · Cited by 69
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Saturnino, C., Petrosino, S., Ligresti, A., Palladino, C., Martino, G., Bisogno, T., & Marzo, V. D. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.11.134 · Cited by 49
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Janero, D. R., Vadivel, S. K., & Makriyannis, A. (2009) · International Review of Psychiatry · doi:10.1080/09540260902782778 · Cited by 37
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Metadata
- Authors
- Re, G., Barbero, R., Miolo, A., & Di Marzo, V.
- Affiliations
- University of Turin (IT)
- Corresponding author
- Re, G.
- ORCID
- Venue
- The Veterinary Journal
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 173
- Issue
- 1
- Pages
- 21-30
- ISSN
- 1090-0233 (ISSN-L)
- OpenAlex
- W2037219926
- Cited by
- 199
- References
- 91
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 6 · 2023: 9 · 2022: 6 · 2021: 10 · 2020: 10 · 2019: 6 · 2018: 9 · 2017: 13 · 2016: 13 · 2015: 13 · 2014: 10 · 2013: 12 · 2012: 17
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Veterinary Journal (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Keywords
- palmitoylethanolamide, endocannabinoids, anandamide, anti-inflammatory activity, analgesia, neuropathic pain, pruritus, mast cells, TRPV1, entourage effect, fatty acid amides, tissue damage, companion animals
- MeSH terms
- Amides, Analgesics, Animals, Cannabinoids, Ethanolamines, Inflammation, Pain, Palmitic Acids, Endocannabinoids
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