The DOI matches its Crossref record; 16 of the 17 references it cites were found in a registry or an index.
Retinal nerve fiber layer thinning in Parkinson disease
Open accessAbstract
Retinal dopamine loss in Parkinson disease (PD) is reflected by visual neurophysiological dysfunction. We measured the thickness of the circumpapillary retinal nerve fiber layer (RNFL) in PD patients using optical coherence tomography. The thickness in the inferior quadrant of PD patients (147 +/- 20 microns) was significantly thinner than that of controls (173 +/- 12 microns; p=0.002), while the inferotemporal area was the thinnest (146 +/- 24 vs. 191 +/- 21 microns; p=0.0003). The results show significant loss of RNFL thickness in PD at specific sites.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“As mentioned above, PD is a motor disorder associated with degeneration of dopaminergic neurons in the substantia nigra (Inzelberg et al., 2004).”
From The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma. (2017) · cites this paper as Inzelberg et al., 2004
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(1992) · American Orthoptic Journal · doi:10.1080/0065955x.1992.11981920 · Cited by 538
Correlation between morphological and functional retinal impairment in multiple sclerosis patients.
Parisi, V., Manni, G., Spadaro, M., Colacino, G., Restuccia, R., Marchi, S., Bucci, M. G., & Pierelli, F. (1999) · PubMed · Cited by 357
Kanamori, A., Nakamura, M., Escaño, M. F., Seya, R., Maeda, H., & Negi, A. (2003) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(02)02003-2 · Cited by 336
Correlation between morphological and functional retinal impairment in multiple sclerosis patients
Sacco, R., Servillo, G., Dinacci, D., Bonavita, S., Lavornia, L., Gallo, A., Ammendola, A., Lanza, M., Costanzo, A. D., Rosa, N., et al. (2007) · Cited by 323
Blumenthal, E. Z., Williams, J., Weinreb, R. N., Girkin, C. A., Berry, C. C., & Zangwill, L. M. (2000) · Ophthalmology · doi:10.1016/s0161-6420(00)00341-9 · Cited by 316
Bodis-Wollner, I. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90113-o · Cited by 296
Decreased dopamine in the retinas of patients with Parkinson's disease.
Harnois, C., & Paolo, T. D. (1990) · PubMed · Cited by 281
Neurobiology of retinal dopamine in relation to degenerative states of the tissue
Djamgoz, M. B. A., Hankins, M. W., Hirano, J., & Archer, S. N. (1997) · Vision Research · doi:10.1016/s0042-6989(97)00129-6 · Cited by 274
Visual dysfunction, neurodegenerative diseases, and aging
Jackson, G. R., & Owsley, C. (2003) · Neurologic Clinics · doi:10.1016/s0733-8619(02)00107-x · Cited by 226
Progressive Worsening of Spatial and Chromatic Processing Deficits in Parkinson Disease
Diederich, N. J., Raman, R., Leurgans, S. E., & Goetz, C. G. (2002) · Archives of Neurology · doi:10.1001/archneur.59.8.1249 · Cited by 150
Flagged first, then by citations
1 of the 17 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 201–300 of 343
Early detection of Parkinson's disease: Retinal functional impairments as potential biomarkers
Linan, V. S., Rioux, V., Peralta, M. R., Dupré, N., Hébert, M., & Lévesque, M. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106872 · Cited by 13
“…responses, and thinning of the retinal nerve fiber layer (Moschos et al., 2011; Veys et al., 2019; Altintas¸ et al., 2008; Hajee et al., 2009; Inzelberg et al., 2004), with DA precursor administration partially restoring visual responses in PD patients (London et al., 2013; Onofrj et al.,…”
Lin, J., Finkelstein, D. I., Anderson, A. J., Lee, P. Y., Bui, B. V., Wijeratne, T., Alty, J., & Nguyen, C. T. O. (2025) · Journal of Neurology · doi:10.1007/s00415-025-13080-6 · Cited by 11
“Inzelberg et al. [113] in 2004 was the first to examine OCT in pwPD and found a significant decrease in retinal nerve fiber layer (RNFL, axons of ganglion cells) thickness in pwPD compared with age-matched controls.”
Optical coherence tomography and cognitive dysfunction in Parkinson disease
Elkhatib, T. H. M., Hashim, N. A., Emad, E. M., Zein, H., & El-aidy, L. A. (2019) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-019-0097-4 · Cited by 16
Quagliato, L. B., Domingues, C., Quagliato, E. M. A. B., Abreu, E. B., & Kara-Júnior, N. (2014) · Arquivos Brasileiros de Oftalmologia · doi:10.5935/0004-2749.20140061 · Cited by 12
“Previous reports of OCT studies described a thinner RNFL in PD patients((10,11,13)).”
BackgroundResultOptic Disc and Retinal Nerve Fibre Layer Changes in Parkinson’s Disease
Çetin, E. N., Bir, L. S., Saraç, G., Yaldızkaya, F., & Yaylalı, V. (2013) · Neuro-Ophthalmology · doi:10.3109/01658107.2012.757788 · Cited by 12
“It is suggested that dopaminergic loss in the retina might alter visual processing by modifications of receptive field properties of ganglion cells and their axons which form the RNFL.1,4 Reduced dopaminergic input to a group of ganglion cells might cause abnormal production of glutamate and atrophy of these selected…”
BackgroundInfluentialMoon, S., Jeon, S., Seo, S. K., Kim, D. E., Jung, N., Kim, S. J., Lee, M. J., Lee, J. W., & Kim, E. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12041310 · Cited by 11
Batum, M., Ak, A. K., Arı, S., Mayalı, H., Kurt, E., & Selçuki, D. (2022) · Documenta Ophthalmologica · doi:10.1007/s10633-022-09887-7 · Cited by 11
“In some studies comparing the PD and control groups, a decrease in thickness of pRFNL was found to be more prominent in PD, especially in average, inferior, superior, and temporal quadrants [24, 30, 37, 38], but others did not show such a difference [32, 39].”
BackgroundLoewenstern, J., Hernandez, C. M., Chadwick, C., Doshi, A. H., Banik, R., Sarkiss, C. A., Bederson, J. B., & Shrivastava, R. K. (2017) · World Neurosurgery · doi:10.1016/j.wneu.2017.10.018 · Cited by 11
ALICI, S., Onur, Ö. Ş., Cavusoglu, E., Onur, İ. U., & Erkıran, M. (2019) · Archives of Clinical Psychiatry (São Paulo) · doi:10.1590/0101-60830000000210 · Cited by 11
Ayyıldız, T., & Ayyıldız, D. (2019) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2019.1633007 · Cited by 10
Optical coherence tomography in patients with Parkinson’s disease
Elkattan, M., Esmat, S. M., Esmail, E. H., Deraz, H. A., & Ismail, R. S. (2022) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-021-00421-1 · Cited by 10
“(2004) [19] who reported thinned average RNFL, specifically in the inferior and temporal quadrants in a small group of 10 PD patients.”
BackgroundDias‐Santos, A., Ferreira, J., Pinheiro, S., Cunha, J. P., Alves, M., Papoila, A. L., Moraes‐Fontes, M. F., & Proença, R. D. (2020) · Eye · doi:10.1038/s41433-020-01292-1 · Cited by 10
Motor Asymmetry and Interocular Retinal Thickness in Parkinson's Disease
Baek, S. U., Kang, S. Y., Kwon, S., Park, I. W., & Suh, W. (2021) · Journal of Korean Medical Science · doi:10.3346/jkms.2021.36.e50 · Cited by 9
Alizadeh, Y., Panjtanpanah, M. R., Mohammadi, M. J., Behboudi, H., & Leili, E. K. (2014) · PubMed Central · Cited by 9
Yıldız, D., Pekel, N. B., Yener, N. P., Seferoğlu, M., Güneş, A., & Sığırlı, D. (2019) · Annals of Indian Academy of Neurology · doi:10.4103/aian.aian_424_17 · Cited by 9
Karadağ, O., Kocamaz, M., Dastan, M., & Durur, S. O. (2020) · Cutaneous and Ocular Toxicology · doi:10.1080/15569527.2020.1778015 · Cited by 9
“The common pathological conditions leading to this are ischaemic optic neuropathy, optic neuritis, hereditary optic neuropathy, traumatic optic neuropathy, multiple sclerosis, and degenerative diseases such as Alzheimer ’ s and Parkinson 18 – 25 .”
BackgroundŞahin, T., Karadere, M. E., Yıldız, V., & Cobanoglu, E. (2021) · Journal Français d Ophtalmologie · doi:10.1016/j.jfo.2020.11.009 · Cited by 9
Dereci, S., Pirgon, Ö., Akçam, M., Türkyılmaz, K., & Dündar, B. N. (2015) · European Journal of Ophthalmology · doi:10.5301/ejo.5000587 · Cited by 9
“Various neurodegenerative diseases can affect RNFL thickness (11-14).”
BackgroundRecent advances in the use of optical coherence tomography in neuro‐ophthalmology: A review
Ge, J. Y., Teo, Z. L., & Loo, J.-L. (2024) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.14341 · Cited by 8
“100,101 Recent research has focused on OCT changes in individuals with rapid eye movement sleep behaviour disorders (RBD), considered a prodromal stage of PD, revealing both pRNFL and mGCIPL thinning in these individuals.”
BackgroundVerghese, S., Berkowitz, S. T., Shah, V. M., Shah, P. K., Priya, S., Saravanan, V., Narendran, V., & Selvan, V. (2022) · Indian Journal of Ophthalmology · doi:10.4103/ijo.ijo_1409_21 · Cited by 8
Restless legs syndrome in multiple sclerosis is related to retinal thinning
Akmaz, O., Köşkderelioğlu, A., Eşkut, N., Şahan, B., & Küsbeci, T. (2022) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.103169 · Cited by 8
Obís, J., García‐Martín, E., Orduna, E., Viladés, E., Alarcia, R., Rodrigo, M. J., Pablo, L. E., Polo, V., Poves, J. M. L., & Satué, M. (2020) · Arquivos Brasileiros de Oftalmologia · doi:10.5935/0004-2749.20200008 · Cited by 8
“Moreover, decreased thickness of the retinal nerve fiber layer (RNFL) in the peripapillary area has been noted, especially in the temporal and inferior quadrants(6-9).”
BackgroundResultReduction of Retinal Thickness Ipsilateral to Hippocampal Sclerosis in Epilepsy
Xiong, W., Lu, L., Chen, Q., Xiao, Y., An, D., Sander, J. W. A. S., Zhang, M., & Zhou, D. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.663559 · Cited by 8
“There is growing evidence that retinal changes may provide a directly observable “window” to identify CNS abnormalities mainly in neurodegenerative diseases such as AD (8), PD (9), multiple sclerosis (10), and other conditions such as epilepsy (4), and schizophrenia (11).”
BackgroundTuncer, Z., Can, G. D., Keklikoğlu, H. D., Eren, F. A., Yülek, F., & Denız, O. (2023) · Parkinson s Disease · doi:10.1155/2023/7739944 · Cited by 8
Ong, Y., Ong, Y., Ikram, M. K., Chen, C., & Wong, T. Y. (2014) · Proceedings of Singapore Healthcare · doi:10.1177/201010581402300112 · Cited by 8
Parkinson's Disease, Aging, and Visual Cognition
Antal, A., Terney, D., & Bodis-Wollner, I. G. (2008) · Topics in Geriatric Rehabilitation · doi:10.1097/01.tgr.0000318903.80066.e7 · Cited by 8
The Impact of the Eye in Dementia: The Eye and its Role in Diagnosis and Follow‐up
Salobrar‐García, E., Ramirez, A. I., de Hoz, R., Rojas, P., Salazar, J. J., Rojas, B., Yubero, R., Gil, P., Triviño, A., & Ramirez, J. M. (2016) · InTech eBooks · doi:10.5772/64490 · Cited by 10
“The retinas of PD patients show photoreceptor and RGC dysfunction, morphological deterioration of the perifoveal dopaminergic plexus [165], and thinning of the RNFL [52, 53, 164, 166, 167].”
BackgroundObís, J., Satué, M., Alarcia, R., Pablo, L. E., & García‐Martín, E. (2018) · Archivos de la Sociedad Española de Oftalmología · doi:10.1016/j.oftal.2018.01.004 · Cited by 8
“Grupo, año n OCT Análisis Correlaciones 5 Inzelberg et al., 2004 10 EP, 10 C TD CFNR peripapilar; ↓ en Inf (↓15,03”
BackgroundSensory symptoms in Parkinson's disease
Djaldetti, R., & Melamed, E. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)83016-8 · Cited by 7
Minor retinal degeneration in Parkinson’s disease
Huang, Y. M., & Yin, Z. Q. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2010.09.016 · Cited by 7
“process, as a significant reduction in RNFL thickness was observed in L-DOPA treated PD patients [35].”
BackgroundEleftheriou, A., Huang, Y.-M., & Lundin, F. (2021) · World Neurosurgery · doi:10.1016/j.wneu.2021.01.003 · Cited by 7
“27,28 29-31 Retinal thinning (RNFL and GCL reduction) has been observed in patients with neurodegenerative diseases such as Parkinson disease 17,32,33 and AD.”
BackgroundMitochondrial morphology and synaptic structure altered in the retina of parkin-deficient mice
Hu, Z.-X., Pu, J., Zheng, R., Yan, Y.-Q., Liu, K.-Y., Liu, Y., Zheng, R., Chen, Y., Lin, Z., Xue, N., et al. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136888 · Cited by 7
Optic nerve head, retinal nerve fiber layer and macular thickness analysis in restless legs syndrome
Köşkderelioğlu, A., Küsbeci, T., Küsbeci, Ö. Y., & Gedizlioğlu, M. (2016) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2016.08.003 · Cited by 7
“Previous studies pointed at a decreased peripapillary RNFL thickness in the inferior, inferotemporal and superotemporal quadrants in patients with PD [10,13,21].”
BackgroundSvetozarskiy, S. N., Kopishinskaya, S. V., & Глебович, С. И. (2020) · Medical Hypothesis Discovery & Innovation in Optometry · doi:10.51329/mehdioptometry103 · Cited by 6
“The study of retinal structures in neurodegenerative diseases has been performed by various teams since 2004 [24].”
BackgroundInterocular asymmetry of retinal change in Parkinson's disease
Zhang, Y., Li, Y., Lai, C., Wang, X., Luo, F., Qin, Y., Qin, Y., Zhang, Y., & Zhang, H. (2024) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2024.107037 · Cited by 5
Xiao, K., Li, J., Zhou, L., Liu, X., Xiao, Z., He, R., Chu, H., Tang, Y., Liu, P., & Lu, X. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.11.073 · Cited by 5
Bernardin, F., Schwitzer, T., Angioï-Duprez, K., Giersch, A., Ligier, F., Bourion-Bédès, S., Jansen, C., Schwan, R., & Laprévote, V. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13103 · Cited by 5
Retinal imaging: what the neurologist needs to know
Xue, K., & Hildebrand, G. D. (2013) · Practical Neurology · doi:10.1136/practneurol-2012-000470 · Cited by 5
Can optical coherence tomography findings be related with suicide attempt in bipolar disorder?
Onur, Ö. Ş., Yeşilkaya, Ü. H., Subaş, E., Açar, Ö. P. A., Onur, İ. U., Karamustafalıoğlu, N., & Eriş, E. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2022.103268 · Cited by 5
Do you have restless leg syndrome? I understood from your eyes
Özlece, H. K., Solmaz, V., Özal, S. A., & Çelik, Y. (2018) · Sleep And Breathing · doi:10.1007/s11325-018-1740-5 · Cited by 5
Lin, M., Chen, M., Zhu, M., & Li, M. D. D.-K. (2025) · Science Progress · doi:10.1177/00368504251377961 · Cited by 4
Imaging in Neuro-ophthalmology
Othman, B. A. A., Kini, T. A., Costello, F., & Lee, A. G. (2022) · Springer eBooks · doi:10.1007/978-3-030-42634-7_39 · Cited by 4
OCT Findings in Patients with Methamphetamine Use Disorder
Kaya, Ş., & Kaya, M. K. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13020308 · Cited by 4
“OCT is prominent in the diagnosis and follow-up of retinal diseases and the number of studies examining retinal and neural network changes in neurodegenerative diseases such as Alzheimer’s and Parkinson’s Diseases is increasing [12,13].”
BackgroundÇoban, F., Kaplan, F. B., Akkaya, S., Okuroğlu, N., & Açıkalın, B. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103713 · Cited by 4
Maio, L. G. D., Cennamo, G., Montorio, D., Michele, G. D., Palmieri, G. R., Baratto, L., Perillo, S., Giglio, A., Filla, A., Morra, V. B., et al. (2024) · Acta Neurologica Scandinavica · doi:10.1155/2024/8555083 · Cited by 4
“Previous studies have already reported thinning of the outer plexiform layer, inner plexiform layer (IPL), ganglion cell layer, and RNFL in PD [9 – 14].”
The Role of the Ganglion Cell Layer as an OCT Biomarker in Neurodegenerative Diseases
Ruggeri, F., Fumi, D., Bassis, L., Pippo, M. D., & Abdolrahimzadeh, S. (2025) · Journal of Integrative Neuroscience · doi:10.31083/jin26039 · Cited by 5
Psychiatric Disorders And Eye: Optical Coherent Tomography In Psychiatry Aspect
Karadağ, A. S., & Kalenderoğlu, A. (2017) · Journal of Clinical Psychiatry · doi:10.5505/kpd.2017.69077 · Cited by 4
“hastalýðýn kliniðine paralel olarak retinada dejenerasyonu tespit edilmiþtir (5-8).”
OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN PARKINSON'S AND ALZHEIMER'S DISEASE
Bayram, D., Yüksel, G. A., Bayram, T., & Tireli, H. (2019) · Nöro Psikiyatri Arşivi · doi:10.29399/npa.23640 · Cited by 4
“In this study including 10 Parkinson’s patients, they showed significant decrease in the inferior RNFL thickness (18).”
Suciu, V.-I., Suciu, C.-I., Nicoară, S., & Perju‐Dumbravă, L. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12010080 · Cited by 6
“In 2004, Inzelberg and colleagues studied the thickness of the peripapillary retinal nerve fiber layer in PD by using an OCT device, and demonstrated that the temporal-inferior (TI) sector was thinner in PD compared to the healthy controls [13].”
BackgroundMethodInfluentialStroe, A. Z., Jurja, S., Stuparu, A. F., & Axelerad, A. D. (2023) · Neurology International · doi:10.3390/neurolint15010012 · Cited by 4
Usefulness of Optical Coherence Tomography Measures as Biomarkers in Schizophrenia
Rodríguez–Jiménez, R. (2018) · Journal of Neurology and Neuromedicine · doi:10.29245/2572.942x/2018/4.1205 · Cited by 4
Santano, C., de Lara, M. P., & Pintor, J. J. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-956-7_10 · Cited by 4
Seiple, W., Jennings, D. L., Rosen, R. B., Borchert, L. D., Canale, L., Fagan, N. M., & Gordon, M. F. (2016) · Parkinson s Disease · doi:10.1155/2016/8298503 · Cited by 4
Gupta, S. D., Dhawan, A., Kakkar, A., Shakeel, T., & Verma, A. K. (2023) · Taiwan Journal of Ophthalmology · doi:10.4103/tjo.tjo-d-22-00142 · Cited by 3
Patel, K., Klifto, M. R., Fleischman, D., Ciociola, E. C., Blahnik, T., & Ghosh, A. (2023) · JOURNAL OF CURRENT GLAUCOMA PRACTICE · doi:10.5005/jp-journals-10078-1415 · Cited by 3
Retinal changes in generalized anxiety disorder patients
Baykara, S., Kılıçaslan, A. K., Yıldırım, H., Tabara, M. F., Kaşıkçı, H. Ö., & Keleş, D. D. (2023) · The International Journal of Psychiatry in Medicine · doi:10.1177/00912174231209771 · Cited by 4
Assessment of RNFL and macular changes in the eye related to multiple substance use using OCT
Kaya, Ş., & Kaya, M. K. (2024) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2024.111889 · Cited by 3
Chiang, C. Y. N., Miléa, D., & Girard, M. J. A. (2025) · Springer eBooks · doi:10.1007/978-3-031-72156-4_26 · Cited by 3
Kani, A. S., Cam, C., Çelik, E. B., Dural, U., Dönmez, M., Turhan, S. A., Toker, E., & Yıldız, M. (2023) · Clinical and Experimental Health Sciences · doi:10.33808/clinexphealthsci.1331234 · Cited by 3
Karatzetzou, S., Parissis, D., Ioannidis, S., Afrantou, T., & Ioannidis, P. (2024) · Applied Sciences · doi:10.3390/app14062491 · Cited by 3
Primary Visual and Visuocognitive Deficits
Bodis-Wollner, I. G., & Antal, A. (2012) · Humana Press eBooks · doi:10.1007/978-1-60761-429-6_22 · Cited by 3
Miri, S., Glazman, S., & Bodis-Wollner, I. G. (2016) · Springer eBooks · doi:10.1007/978-3-319-24085-5_6 · Cited by 3
Retinal nerve fiber layer thickness in patients with essential tremor and Parkinson’s disease
Fidancı, H., Öksüz, N., Özal, Ş., Adıgüzel, U., KALEAĞASI, Ş. H., & Doğu, O. (2019) · Journal of Surgery and Medicine · doi:10.28982/josam.661757 · Cited by 3
“Akin to these previous studies [8,25,26], in our study, peripapillary RNFL thickness in all quadrants was thinner in Parkinson’s patients compared to the controls.”
BackgroundResultMRI findings of visual system alterations in Parkinson’s disease
Arrigo, A., Calamuneri, A., Mormina, E., Aragona, P., Gaeta, M., & Quartarone, A. (2017) · Brain · doi:10.1093/brain/awx244 · Cited by 3
Shi, H., Wei, J., Jin, R., Peng, J., Wang, X., Hu, Y., Zhang, X., & Liu, J. (2024) · Computerized Medical Imaging and Graphics · doi:10.1016/j.compmedimag.2024.102463 · Cited by 2
Moon, C., Lee, S., Shin, H., Kim, H., Lee, J.-K., Kim, H., Kang, H. S., Moon, I. H., Kim, S. S., Lee, H. K., et al. (2026) · npj Parkinson s Disease · doi:10.1038/s41531-026-01261-7 · Cited by 2
Evaluation of Optical Coherence Tomography Findings in Antisocial Personality Disorder Patients
Emir, B. S., Yıldız, S., Kılıçaslan, A. K., Kurt, O., Keser, S., & Uğur, K. (2023) · ALPHA PSYCHIATRY · doi:10.5152/alphapsychiatry.2023.221108 · Cited by 2
Hopf, S., Tüscher, O., & Schuster, A. K.-G. (2024) · Die Ophthalmologie · doi:10.1007/s00347-023-01974-7 · Cited by 2
Evaluation of insomnia effect on ganglion cell complex, middle retina, and choroid
Sozen-Delil, F. I., Comba, O. B., & Ucar, G. (2024) · International Ophthalmology · doi:10.1007/s10792-024-03303-6 · Cited by 2
“Thinning of the RNFL thickness, shown on OCT in neurodegenerative and demyelinating diseases, has been observed in previous studies [14, 15].”
Macular and Retinal Nerve Fibre Layer Thinning in Xeroderma Pigmentosum: A Cross-sectional Study
Gruener, A. M., & Morley, A. M. S. (2018) · Neuro-Ophthalmology · doi:10.1080/01658107.2018.1452038 · Cited by 2
Discharge responses of the optic tract to flash stimuli in Parkinson's disease
Hashimoto, T., Katai, S., & Goto, T. (2014) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.50 · Cited by 2
OCT in Parkinson’s Disease and Related Disorders
Bodis-Wollner, I. G., Miri, S., Glazman, S., Shrier, E. M., & Deeb, R. (2020) · Springer eBooks · doi:10.1007/978-3-030-26269-3_12 · Cited by 2
Keskinrüzgar, A., Küçük, A. Ö., Acibadem, E., Yapici-Yavuz, G., Karadağ, A. S., Şimşek, A., & Koparal, M. (2020) · Journal of Stomatology Oral and Maxillofacial Surgery · doi:10.1016/j.jormas.2020.05.014 · Cited by 2
Dopaminergic Basis of Spatial Deficits in Early Parkinson’s Disease
Hanna‐Pladdy, B., Pahwa, R., & Lyons, K. E. (2021) · Cerebral Cortex Communications · doi:10.1093/texcom/tgab042 · Cited by 2
“…thickness in PD associated with visual alterations and reduced contrast sensitivity which should be explored further as potential early markers in PD (Inzelberg et al. 2004; Armstrong 2011; Bertrand et al. 2012; Adam et al. 2013; Li et al. 2015; Polo et al. 2016; Yang et al. 2016; Shi et al. 2020).”
BackgroundNeurodegeneration with Brain Iron Accumulation Disorders and Retinal Neurovascular Structure
Amini, E., Rohani, M., Fasano, A. A., Azad, Z., Miri, S., Habibi, S. A. H., Emamikhah, M., Mirshahi, R., Joghataei, M. T., Gholibeigian, Z., et al. (2023) · Movement Disorders · doi:10.1002/mds.29644 · Cited by 2
“20-25 Although the retina ’ s unique neurovascular structure makes it an attractive target for studying neurodegenerative disorders, speci fi c research on NBIA disorders is limited.”
BackgroundNeuro-Ophthalmologic Evaluation as a Biomarker for Diagnosis and Progression in Parkinson Disease
Satué, M., Polo, V., Otin, S., Larrosa, J. M., Obís, J., & García‐Martín, E. (2016) · InTech eBooks · doi:10.5772/62877 · Cited by 2
Pinkhardt, E. H., Ding, Y., Slotnick, S., Kassubek, J., Ludolph, A. C., Glazman, S., Selesnick, I., & Bodis-Wollner, I. G. (2020) · Journal of Neural Transmission · doi:10.1007/s00702-020-02224-9 · Cited by 2
Gaynes, B. I. (2006) · Brain · doi:10.1093/brain/awl292 · Cited by 2
Non-glaucomatous peripapillary retinal nerve fiber layer defect
Wei, W., Pan, C., & Zhou, J. (2013) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20130148 · Cited by 1
The Effects of Pyridoxine on Retinal Nerve Fiber Layer in Tuberculous Treatment
Fındık, H., Gümüş, A., Okutucu, M., ASLAN, M. G., Koç, H., & Feyzahan, U. Z. U. N. (2019) · Düzce Tıp Fakültesi Dergisi · doi:10.18678/dtfd.515313 · Cited by 1
“Several neurodegenerative (10,11) and some metabolic diseases (12,13) affect RNFL thickness.”
BackgroundLinan, V. S., Hébert, M., & Lévesque, M. (2025) · Journal of Parkinson s Disease · doi:10.1177/1877718x251331863 · Cited by 1
Tonkaz, G. Y., Önal, B. S., Özyurt, G., ÇAKIR, A., Utlu, B., & Şahin, B. (2025) · Namık Kemal Tıp Dergisi · doi:10.4274/nkmj.galenos.2025.53244 · Cited by 1
Bozkurt, E., Muhafız, E., Erdoğan, C. E., Nizamoğulları, Ş., Toprak, G., & Meydan, B. (2025) · BMC Ophthalmology · doi:10.1186/s12886-025-04219-0 · Cited by 1
“Structural retinal changes have been noted in PD, including thinning of the inner retinal layers, particularly the ganglion cell layer (GCL) and inner nuclear layer (INL), possibly related to alpha-synuclein accumulation [4, 13, 14].”
Retinal Imaging Techniques for Neurodegenerative Diseases: Parkinson's Disease and Beyond
Tang, C., Zhang, X., Miao, H., Wang, X., & Liu, J. (2025) · MedComm – Future Medicine · doi:10.1002/mef2.70034 · Cited by 1
Svetel, M., Maric, G. D., Božić, M., Tatjana, P., Petrović, I. N., Jakšić, J., Dimitrijevic, A. M., Lazić, U., Kostić, S., Knežević, M., et al. (2026) · Biomedicines · doi:10.3390/biomedicines14010249 · Cited by 1
Glokom, Parkinson hastalığı ve nörodejenerasyon
Balci, S. Y., Eraslan, M., & Temel, A. (2015) · Marmara medical journal · doi:10.5472/mmj.2015.03691.1 · Cited by 1
Visual impairment in Parkinson's disease
Arrigo, A., Calamuneri, A., Aragona, E., Mormina, E., & Gaeta, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815946-0.00012-0 · Cited by 1
Neurodegenerative changes of retina in Parkinson disease
Fedotova, E. Y., Полькина, Н. В., Mikhailova, E. N., & Illarioshkin, S. N. (2022) · Russian neurological Journal · doi:10.30629/2658-7947-2021-26-6-29-34 · Cited by 1
Retinal Changes in Panic Disorder Patients
Baykara, S., Yıldırım, H., Kılıçaslan, A. K., Tabara, M. F., Keleş, D. D., Gürok, M. G., & Atmaca, M. (2022) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2022.111496 · Cited by 3
Başkan, C., Akman, A. Ö., Akçay, E., Gökçe, S. E., & Taş, D. (2024) · Arquivos Brasileiros de Oftalmologia · doi:10.5935/0004-2749.2023-0047 · Cited by 1
Manchanda, R., Samanta, R., Narayan, M. L., Kumar, M., Tiwari, A., Agarwal, A., Bahurupi, Y. A., Kumari, S., & Kumar, N. (2024) · Annals of Indian Academy of Neurology · doi:10.4103/aian.aian_31_24 · Cited by 1
Parkinson Hastalığında Retina Sinir Lifi Tabakası ve Makula Kalınlığının Değerlendirilmesi
Dikkaya, F., Özkök, A., & Delil, Ş. (2018) · Dicle Medical Journal / Dicle Tip Dergisi · doi:10.5798/dicletip.457264 · Cited by 1
La retina como marcador biológico de daño neuronal
Pueyo, V., Ara, J. R., & Martín, J. (2010) · Archivos de la Sociedad Española de Oftalmología · doi:10.1016/s0365-6691(10)55001-9 · Cited by 1
The retina as a biological marker of neuronal damage
Pueyo, V., Ara, J. R., & Martín‐Vallejo, J. (2010) · Archivos de la Sociedad Española de Oftalmología (English Edition) · doi:10.1016/s2173-5794(10)70030-x · Cited by 1
Castelo-Branco, M. S., Silva, M. F., Januário, C., & Freire, A. (2006) · Brain · doi:10.1093/brain/awl293 · Cited by 1
“First, as can be easily appreciated from the title of the single paper that is cited in this context (Inzelberg et al., 2004), it is not true that the diameter of retinal ganglion cell axons is being measured.”
Peripapillary retinal nerve fibre layer thickness in individuals with epilepsy exposed to vigabatrin
Clayton, L. M. S. (2011) · UCL Discovery (University College London)
Jindahra, P. (2011) · UCL Discovery (University College London)
Stellenwert einer perimetrischen Differenzialdiagnostik beim primären Offenwinkelglaukom
Erb, C., & Göbel, K. (2013) · Der Ophthalmologe · doi:10.1007/s00347-012-2691-z
Erratum zu: Therapie posterior gelegener Orbitatumoren
Maier, W., Ridder, G. J., Kaminsky, J., & Grosu, A. (2011) · Der Ophthalmologe · doi:10.1007/s00347-011-2417-7
Metadata
- Authors
- Inzelberg, R., Ramirez, J. A., Nisipeanu, P., & Ophir, A.
- Affiliations
- Technion – Israel Institute of Technology (IL)
- Hillel Yaffe Medical Center (IL)
- Corresponding author
- Ophir, Avinoam
- ORCID
- Inzelberg, Rivka
- Venue
- Vision Research
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 44
- Issue
- 24
- Pages
- 2793-2797
- ISSN
- 0042-6989 (ISSN-L)
- OpenAlex
- W1974244012
- Cited by
- 343
- References
- 17
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 15 · 2023: 13 · 2022: 25 · 2021: 15 · 2020: 30 · 2019: 20 · 2018: 21 · 2017: 26 · 2016: 21 · 2015: 27 · 2014: 23 · 2013: 21 · 2012: 22
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Vision Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Health, State of Israel
- Topics
- Health Sciences › Medicine › Ophthalmology › Glaucoma and retinal disorders
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Ophthalmology › Drug-Induced Ocular Toxicity
- Keywords
- Parkinson's disease, retinal nerve fiber layer, retinal nerve fiber layer thickness, optic nerve head, retinal neurodegeneration
- MeSH terms
- Adult, Aged, Female, Humans, Male, Middle Aged, Nerve Fibers, Parkinson Disease, Retina, Tomography, Optical Coherence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
