The DOI matches its Crossref record; 16 of the 17 references it cites were found in a registry or an index.
Retinal nerve fiber layer thinning in Parkinson disease
Open accessAbstract
Retinal dopamine loss in Parkinson disease (PD) is reflected by visual neurophysiological dysfunction. We measured the thickness of the circumpapillary retinal nerve fiber layer (RNFL) in PD patients using optical coherence tomography. The thickness in the inferior quadrant of PD patients (147 +/- 20 microns) was significantly thinner than that of controls (173 +/- 12 microns; p=0.002), while the inferotemporal area was the thinnest (146 +/- 24 vs. 191 +/- 21 microns; p=0.0003). The results show significant loss of RNFL thickness in PD at specific sites.
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“As mentioned above, PD is a motor disorder associated with degeneration of dopaminergic neurons in the substantia nigra (Inzelberg et al., 2004).”
From The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma. (2017) · cites this paper as Inzelberg et al., 2004
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Metadata
- Authors
- Inzelberg, R., Ramirez, J. A., Nisipeanu, P., & Ophir, A.
- Affiliations
- Technion – Israel Institute of Technology (IL)
- Hillel Yaffe Medical Center (IL)
- Corresponding author
- Ophir, Avinoam
- ORCID
- Inzelberg, Rivka
- Venue
- Vision Research
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 44
- Issue
- 24
- Pages
- 2793-2797
- ISSN
- 0042-6989 (ISSN-L)
- OpenAlex
- W1974244012
- Cited by
- 343
- References
- 17
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 15 · 2023: 13 · 2022: 25 · 2021: 15 · 2020: 30 · 2019: 20 · 2018: 21 · 2017: 26 · 2016: 21 · 2015: 27 · 2014: 23 · 2013: 21 · 2012: 22
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Vision Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Health, State of Israel
- Topics
- Health Sciences › Medicine › Ophthalmology › Glaucoma and retinal disorders
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Ophthalmology › Drug-Induced Ocular Toxicity
- Keywords
- Parkinson's disease, retinal nerve fiber layer, retinal nerve fiber layer thickness, optic nerve head, retinal neurodegeneration
- MeSH terms
- Adult, Aged, Female, Humans, Male, Middle Aged, Nerve Fibers, Parkinson Disease, Retina, Tomography, Optical Coherence
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