Depression and anxiety in children and adolescents with epilepsy: Prevalence, risk factors, and treatment
Open accessAbstract
Among the psychiatric comorbid conditions in children and adolescents with epilepsy, depression and anxiety disorders require further attention because they carry the risk of reduced quality of life and life-threatening complications (e.g., suicide). Research in recent years has shed light on both the prevalence of emotional problems in youth with epilepsy and the safety and efficacy of treatment options. A number of challenges exist in treating patients with epilepsy. This is particularly true when seizures are difficult to control and medication regimens are more complex. Some pharmaceutical options may provide assistance with both seizures and emotional distress, but care is needed when considering such treatment approaches. In addition, integration of mental health professionals into the care of patients is necessary when cases are complicated and risk factors are high. Thorough methods to accurately diagnose emotional conditions and regular monitoring of symptoms can help prevent serious problems that can negatively affect the success of children and adolescents in everyday life. Collaboration between disciplines offers the best hope for early identification and treatment of these conditions.
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People with epilepsy are at increased risk of psychiatric comorbidities compared to the general population and non-neurological medical conditions, as well as to people with other neurological diseases.
“People with epilepsy (PWE) are at increased risk of psychiatric comorbidities compared to the general population and nonneurological medical conditions, 3,4 as well as to people with other neurological diseases, 5”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [4]
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- Authors
- Ekinci, O., Titus, J. B., Rodopman, A. A., Berkem, M., & Trevathan, E.
- Affiliations
- St. Louis Children's Hospital (US)
- Marmara University (TR)
- Centers for Disease Control and Prevention (US)
- Venue
- Epilepsy & Behavior
- Publisher
- Elsevier BV
- Published
- 2009-01
- Volume
- 14
- Issue
- 1
- Pages
- 8-18
- ISSN
- 1525-5050 (ISSN-L)
- OpenAlex
- W2112751455
- Cited by
- 186
- References
- 175
- Citations by year
- 2026: 4 · 2025: 11 · 2024: 9 · 2023: 10 · 2022: 10 · 2021: 9 · 2020: 11 · 2019: 14 · 2018: 17 · 2017: 16 · 2016: 7 · 2015: 14 · 2014: 12 · 2013: 10 · 2012: 14
- FWCI
- 0.78
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Epilepsy & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Dspace Repository (Marmara Üniversitesi) (submittedVersion)
- Dspace Repository (Marmara Üniversitesi) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- depression, anxiety disorders, pediatric epilepsy, adolescent epilepsy, psychiatric comorbidity, prevalence, risk factors, treatment, antiepileptic drugs, suicide risk, quality of life, mental health integration, interdisciplinary collaboration, symptom monitoring
- MeSH terms
- Adolescent, Anxiety, Child, Depression, Epilepsy, Humans, Risk Factors, Comorbidity
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