Cited by 102Epilepsy research and treatmentDementia and Cognitive Impairment ResearchCognitive Functions and Memory

A cognitive behavioral intervention (HOBSCOTCH) improves quality of life and attention in epilepsy

Caller, Tracie A., Ferguson, Robert J., Roth, Robert M., Secore, Karen L., Alexandre, Faith P., Zhao, Wenyan, Tosteson, Tor Devin, Henegan, Patricia L. +2 more·2016·Epilepsy & Behavior

Abstract

Objective Cognitive difficulties in epilepsy are common and add to disability beyond seizures alone. A self-management intervention targeting cognitive dysfunction was developed and assessed for whether it improves quality of life, objective memory, and mood in adults with epilepsy.Methods The HOme Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH) program was developed to incorporate (1) psychoeducation, (2) self-awareness training, (3) compensatory strategies, and (4) application of these strategies in day-to-day life using problem solving therapy. Adults aged 18-65 years with epilepsy (n=66) were randomized into 3 groups, to receive 8 weeks of HOBSCOTCH, with (H+) or without (H) additional working memory training on a commercial gaming device, or to a waitlisted control group. The primary outcome was quality of life (Quality of Life in Epilepsy scale, QOLIE-31) with secondary outcomes of objective cognition measured with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and depression (as measured by PHQ9 and NDDIE).Results Both intervention arms showed a significant improvement in quality of life, as compared with controls who demonstrated a decline in QOLIE-31 scores. There was significant improvement in objective cognitive performance among the intervention groups, most notably in attention, compared with the waitlisted controls. There was no significant change in depression scores.Significance The HOBSCOTCH program significantly improved quality of life and appeared to be an effective intervention to address cognitive dysfunction in adults with epilepsy. Further studies are needed to assess the generalizability and cost-effectiveness of this intervention.

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Crossref · 10.1016/j.yebeh.2016.01.024

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Authors
Caller, T. A., Ferguson, R. J., Roth, R. M., Secore, K. L., Alexandre, F. P., Zhao, W., Tosteson, T. D., Henegan, P. L., Birney, K., & Jobst, B. C.
Affiliations
  • Dartmouth–Hitchcock Medical Center (US)
  • Eastern Maine Medical Center (US)
  • Dartmouth College (US)
Corresponding author
Jobst, Barbara C.
Venue
Epilepsy & Behavior
Publisher
Elsevier BV
Published
2016-04
Volume
57
Issue
Pt A
Pages
111-117
ISSN
1525-5050 (ISSN-L)
OpenAlex
W2291286026
Cited by
102
References
35
Citations by year
2026: 13 · 2025: 15 · 2024: 6 · 2023: 6 · 2022: 13 · 2021: 8 · 2020: 10 · 2019: 9 · 2018: 9 · 2017: 9 · 2016: 4
FWCI
9.18
Type
journal article
Language
en
Open access
closed
Locations
  • Epilepsy & Behavior (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Dartmouth College
  • National Center for Chronic Disease Prevention and Health Promotion (U48DP005018, 3U48DP001935-04S3)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords
epilepsy, cognitive impairment, cognitive-behavioral intervention, quality of life, attention, working memory training, compensatory strategies, self-management, problem-solving therapy, psychoeducation, depression, mood, adults with epilepsy
MeSH terms
Adolescent, Adult, Aged, Attention, Cognition, Cognition Disorders, Epilepsy, Female, Humans, Learning, Male, Memory, Short-Term, Middle Aged, Outcome and Process Assessment, Health Care, Quality of Life, Seizures, Self Care, Cognitive Behavioral Therapy, Young Adult

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