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Cited by 388

The DOI matches its Crossref record; 401 of the 401 references it cites were found in a registry or an index.

Escherichia coli as a host for metabolic engineering

Open access
Pontrelli, Sammy, Chiu, Tsan-Yu, Lan, Ethan I., Chen, Frederic Y.-H., Chang, Peiching, Liao, James C.·2018·Metabolic Engineering

Abstract

Over the past century, Escherichia coli has become one of the best studied organisms on earth. Features such as genetic tractability, favorable growth conditions, well characterized biochemistry and physiology, and availability of versatile genetic manipulation tools make E. coli an ideal platform host for development of industrially viable productions. In this review, we discuss the physiological attributes of E. coli that are most relevant for metabolic engineering, as well as emerging techniques that enable efficient phenotype construction. Further, we summarize the large number of native and non-native products that have been synthesized by E. coli, and address some of the future challenges in broadening substrate range and fighting phage infection.

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Registry

Crossref · 10.1016/j.ymben.2018.04.008

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Metadata

Authors
Pontrelli, S., Chiu, T.-Y., Lan, E. I., Chen, F. Y.-H., Chang, P., & Liao, J. C.
Venue
Metabolic Engineering
Publisher
Elsevier BV
Published
2018-11
Volume
50
Pages
16-46
ISSN
1096-7176 (ISSN-L)
OpenAlex
W2800771128
Cited by
388
References
401
FWCI
10.91
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Escherichia coli as a host for metabolic engineering. https://app.cochat.ai/papers/10.1016/j.ymben.2018.04.008
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Pontrelli, S., Chiu, T.-Y., Lan, E. I., Chen, F. Y.-H., Chang, P., & Liao, J. C. (2018). Escherichia coli as a host for metabolic engineering. Metabolic Engineering. https://doi.org/10.1016/j.ymben.2018.04.008

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.