The DOI matches its Crossref record; 263 of the 263 references it cites were found in a registry or an index.
Recent advances in metabolic engineering of Saccharomyces cerevisiae: New tools and their applications
Open accessAbstract
Metabolic engineering aims to develop efficient cell factories by rewiring cellular metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae has been extensively engineered to produce a wide variety of products at high levels from various feedstocks. In this review, we summarize the recent development of metabolic engineering approaches to modulate yeast metabolism with representative examples. Particularly, we highlight new tools for biosynthetic pathway optimization (i.e. combinatorial transcriptional engineering and dynamic metabolic flux control) and genome engineering (i.e. clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated (Cas) system based genome engineering and RNA interference assisted genome evolution) to advance metabolic engineering in yeast. We also discuss the challenges and perspectives for high throughput metabolic engineering.
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Cites
Multiplex Genome Engineering Using CRISPR/Cas Systems
Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science · doi:10.1126/science.1231143 · Cited by 15,339
RNA-Seq: a revolutionary tool for transcriptomics
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RNA-Guided Human Genome Engineering via Cas9
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Development and Applications of CRISPR-Cas9 for Genome Engineering
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Genome-scale CRISPR-Cas9 knockout screening in human cells
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“CRISPRa can be achieved by recruiting an activator domain to the nuclease deficient CRISPR complex (Gilbert et al., 2013; Zalatan et al., 2015) (Fig.”
BackgroundGenome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
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BackgroundProduction of the antimalarial drug precursor artemisinic acid in engineered yeast
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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
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Cited by
Eisenhut, P., Mebrahtu, A., Moradi Barzadd, M., Thalén, N., Klanert, G., Weinguny, M., Sandegren, A., Su, C., Hatton, D., Borth, N., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa847 · Cited by 38
Metadata
- Authors
- Lian, J., Mishra, S., & Zhao, H.
- Venue
- Metabolic Engineering
- Publisher
- Elsevier BV
- Published
- 2018-11
- Volume
- 50
- Pages
- 85-108
- ISSN
- 1096-7176 (ISSN-L)
- OpenAlex
- W2801954748
- Cited by
- 332
- References
- 263
- FWCI
- 11.07
- Type
- journal article
- Language
- en
- Open access
- bronze
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