Machine learning-enabled optimization of extrusion-based 3D printing
Abstract
Machine learning (ML) and three-dimensional (3D) printing are among the fastest-growing branches of science. While ML can enable computers to independently learn from available data to make decisions with minimal human intervention, 3D printing has opened up an avenue for modern, multi-material, manufacture of complex 3D structures with a rapid turn-around ability for users with limited manufacturing experience. However, the determination of optimum printing parameters is still a challenge, increasing pre-printing process time and material wastage. Here, we present the first integration of ML and 3D printing through an easy-to-use graphical user interface (GUI) for printing parameter optimization. Unlike the widely held orthogonal design used in most of the 3D printing research, we, for the first time, used nine different computer-aided design (CAD) images and in order to enable ML algorithms to distinguish the difference between designs, we devised a self-designed method to calculate the "complexity index" of CAD designs. In addition, for the first time, the similarity of the print outcomes and CAD images are measured using four different self-designed labeling methods (both manually and automatically) to figure out the best labeling method for ML purposes. Subsequently, we trained eight ML algorithms on 224 datapoints to identify the best ML model for 3D printing applications. The "gradient boosting regression" model yields the best prediction performance with an R-2 score of 0.954. The ML-embedded GUI developed in this study enables users (either skilled or unskilled in 3D printing and/or ML) to simply upload a design (desired to print) to the GUI along with desired printing temperature and pressure to obtain the approximate similarity in the case of actual 3D printing of the uploaded design. This ultimately can prevent error-and-trial steps prior to printing which in return can speed up overall design-to-end-product time with less material waste and more cost-efficiency.
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During printing, AI algorithms can dynamically adjust parameters such as extrusion speed, nozzle temperature, and layer height to maintain consistent print quality and reduce material waste.
“During the printing process, AI algorithms can dynamically adjust parameters such as extrusion speed [44,44], nozzle temperature, and layer height to maintain consistent print quality and reduce material waste [37].”
From Towards the development of foods 3D printer: Trends and technologies for foods printing (2024) · cites this paper as [37]
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Optimization of 4D/3D printing via machine learning: A systematic review
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A Survey and Perspective on Industrial Cyber-Physical Systems (ICPS): From ICPS to AI-Augmented ICPS
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Machine learning-driven 3D printing: A review
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Point‐of‐Care Diagnostic Platforms for Loop‐Mediated Isothermal Amplification
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Towards the development of foods 3D printer: Trends and technologies for foods printing
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“During the printing process, AI algorithms can dynamically adjust parameters such as extrusion speed [44,44], nozzle temperature, and layer height to maintain consistent print quality and reduce material waste [37].”
BackgroundMethodInfluentialShape Fidelity Evaluation of Alginate-Based Hydrogels through Extrusion-Based Bioprinting
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Advancing 3D Printing through Integration of Machine Learning with Algae‐Based Biopolymers
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Machine Learning in Predicting and Optimizing Polymer Printability for 3D Bioprinting
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“Constructing scaffolds with complex geometries and high-precision details such as porous networks, biomimetic hierarchical structures, or finely branched vasculature requires elevated levels of printing accuracy and material stability [74,75].”
The Role of 3D Printing in Advancing Automated Manufacturing Systems: Opportunities and Challenges
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Bayesian machine learning optimization of microneedle design for biological fluid sampling
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Machine Vision-Based Surface Defect Detection Study for Ceramic 3D Printing
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“Compared to the above, 3D printing has a simple molding, short cycle, is easy to adjust, etc., but because of the extrusion molding process, the material price is more expensive and the printing process is prone to defects and cannot produce printed products that [36].”
Machine learning-assisted extrusion-based 3D bioprinting for tissue regeneration applications
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Machine learning‐enabled optimization of melt electro‐writing three‐dimensional printing
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Additive manufacturing of polymers and composites for applications in aerospace and aeronautics
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3D bioprinting of natural materials and their AI-Enhanced printability: A review
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Designing Emulsion Gels for 3D Food Printing: Structure, Stability, and Functional Applications
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A Path towards SDGs: Investigation of the Challenges in Adopting 3D Concrete Printing in India
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“Machine learning has been successfully applied in various fields such as healthcare, energy, materials, and manufacturing [33–36].”
MethodResearch on 3D printing concrete mechanical properties prediction model based on machine learning
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3D printing of biologics—what has been accomplished to date?
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Machine learning based approach for surface roughness prediction in precision dental prototyping
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“XGBoost is an enhanced version of the Gradient Boosting algorithm also used for the construction of the models of the regression type of supervised machine learning 89 .”
Overview of 3D Printed Exoskeleton Materials and Opportunities for Their AI-Based Optimization
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Accurately Predicting Multiple Performance of 3D Printing Photopolymers Using Ensemble Learning
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Defect detection in 3D printing: a review of image processing and machine vision techniques
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Advances and obstacles to unify the concept of “printability” in Ceramics Direct Ink Writing
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“Instead of manually testing each parameter, machine learning models can learn from previous data to predict the optimal printing parameters based on the desired mechanical properties [15–17].”
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Coaxial Bioprinting in Regenerative Medicine: Advances and Emerging Applications
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Advances in data-driven integrated design synthesis optimization and prediction of carbon nanotube
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Recent Advances in Textile Printing Techniques
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Machine learning integration for smarter, more adaptive systems in large-scale 3D printing
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Examination of 3D printing parameters using machine learning
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“LightGBM (Fig.”
InfluentialArtificial intelligence for marine oil spill management: Recent advances and future directions
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Díez, J. M., Sánchez, L. P., Amilibia, M. Z., Cáceres, M. M. G., Mejia-Parra, D., Arbelaiz, A., Lin, X., & Cortes, C. A. (2026) · The International Journal of Advanced Manufacturing Technology · doi:10.1007/s00170-026-18388-9 · Cited by 1 · see citing works
“A significant bottleneck in existing research is the reliance on manual placement during imaging and assessment [12, 15, 17, 31, 32, 34, 36, 37, 43], the proposed framework includes reference markers for automated registration, allowing the use of a vision system to align the original pattern with…”
InfluentialBakhtiari, M., Sheikh-Ansari, M. H., Borgaonkar, A., Dadkhah, M., & Saboori, A. (2026) · Advanced Engineering Materials · doi:10.1002/adem.71088 · Cited by 2 · see citing works
A Review of Current Progress and Application of Machine Learning on 3D-Printed Concrete
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A Point-Line-Area Paradigm: 3D Printing for Next-Generation Health Monitoring Sensors
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Precision biomaterials printing: The way forward, a paradigm shift
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Optimization Analysis of Product Design Process Based on Reinforcement Learning Algorithm
Hu, Y., & Li, Q. (2024) · Frontiers in artificial intelligence and applications · doi:10.3233/faia231449
Biopolymeric additive manufacturing: The bidirectional interplay of synthetic and natural systemsPreprint
Lew, A. J., Lai, A. F., & Wyman, S. P. (2024) · Preprints.org · doi:10.20944/preprints202403.0657.v1
A Novel Method for Pore Morphology Prediction: Multi-Ghost Encoder Generative Network
Yang, Y., Feng, J., & Liu, X. (2024) · Chinese Control and Decision Conference (CCDC) · doi:10.1109/ccdc62350.2024.10588070
“The application potential of this technique includes identifying and analyzing the patterns of processing parameters on porosity and material properties by processing large-scale data, so as to build predictive models or optimization strategies [4].”
MethodKim, H.-C., Bae, Y.-H., Yun, H., et al. (2024) · Journal of the Korean Society of Manufacturing Process Engineers · doi:10.14775/ksmpe.2024.23.11.020
A Review of Machine Learning for Additive Manufacturing
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Multimaterial printing for medical design
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AI Assisted 3D Food Printing Technology: An Overview
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PLA Damage Properties in FDM Printing: A Hybrid Experimental and Machine Learning Study
Dhouioui, M., Fraj, B. B., Hentati, H., et al. (2025) · Lecture notes in mechanical engineering · doi:10.1007/978-3-031-94889-3_15
3D printing for therapeutic strategy
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Nanofluidics, 3D nano-printing, and organoids for biomedical technology
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AI assisted mechanical and performance testing of lightweight composites
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Intelligent Additive Manufacturing is Unleashing the Power of 3D Printing with Machine Learning
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Prospects of Utilizing Additive Manufacturing Technologies in Photovoltaic Cell Making
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“For instance, Dabbagh et al. [59] used Machine Learning (ML) to optimize extrusion-based printing parameters such as temperature and pressure instead of manual tuning.”
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Applications of Artificial Intelligence and Machine Learning in 3D Concrete Printing
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AI-Enabled Polymer Processing Technology
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Data-driven multi-objective optimization of 3D-printed biodegradable polymer optical fiber preforms
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Lakshmaiya, N. (2026) · Progress in Additive Manufacturing · doi:10.1007/s40964-026-01896-1
Natrayan, L. (2026) · International Conference on Smart Systems and Inventive Technology (ICSSIT) · doi:10.1109/icssit69151.2026.11657648
“…and more cost spent in the wastages, where the machine learning methods consider the feature engineering and classification process for the prediction of defective products in a proactive manner by monitoring the wrong patterns using the rheology-based feature selection processes [2].”
Geometry-aware multi-output learning for interpretable fused deposition modeling configuration
Nguyen, H.-C., Nguyen, N.-D., Pham, V.-H., et al. (2026) · Progress in Additive Manufacturing · doi:10.1007/s40964-026-01961-9
Wang, X., liu, R., wang, J., et al. (2026) · Journal of Materials Chemistry A · doi:10.1039/d6ta06203b
- Authors
- Rahmani Dabbagh, S., Ozcan, O., & Tasoglu, S.
- Venue
- Methods
- Publisher
- Elsevier BV
- Published
- 2022-10
- Volume
- 206
- Pages
- 27-40
- ISSN
- 1046-2023 (ISSN-L)
- OpenAlex
- W4291002276
- Semantic Scholar
- 8c22d14b605943b77065bb467795dae30593ed1a
- Cited by
- 94
- References
- 99
- Citations by year
- 2026: 19 · 2025: 39 · 2024: 20 · 2023: 13 · 2022: 3
- FWCI
- 5.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Methods (publishedVersion)
- PubMed (publishedVersion)
- Digital Collections portal (Koç University) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Automotive Engineering › Additive Manufacturing and 3D Printing Technologies
- Physical Sciences › Materials Science › Materials Chemistry › Machine Learning in Materials Science
- Physical Sciences › Engineering › Building and Construction › Innovations in Concrete and Construction Materials
- Keywords
- material extrusion, printing parameter optimization, machine learning, gradient boosting regression, graphical user interface, material waste reduction
- MeSH terms
- Machine Learning, Algorithms, Humans, Computer-Aided Design, Printing, Three-Dimensional
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