Gut microbiome, big data and machine learning to promote precision medicine for cancer

Search and clustering orders of magnitude faster than BLAST

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Metagenomic biomarker discovery and explanation

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The UK Biobank resource with deep phenotyping and genomic data

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Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors

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Diversity, stability and resilience of the human gut microbiota

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Role of the microbiota in immunity and inflammation.

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Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients

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Machine Learning in Medicine

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Helicobacter pylori Infection and the Risk of Gastric Carcinoma

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Commensal <i>Bifidobacterium</i> promotes antitumor immunity and facilitates anti–PD-L1 efficacy

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Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

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Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk

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The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

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Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

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The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients

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Personalized nutrition by prediction of glycemic responses

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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

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Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

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Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

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The gut microbiota and host health: a new clinical frontier

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Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

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Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

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Shotgun metagenomics, from sampling to analysis

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Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

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The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

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Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

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Immune checkpoint inhibitors: recent progress and potential biomarkers

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Best practices for analysing microbiomes

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Gut microbiome structure and metabolic activity in inflammatory bowel disease

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Genomic analysis identifies association of <i>Fusobacterium</i> with colorectal carcinoma

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Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

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MicrobiomeAnalyst: a web-based tool for comprehensive statistical, visual and meta-analysis of microbiome data

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

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Composition, variability, and temporal stability of the intestinal microbiota of the elderly

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Artificial intelligence in digital pathology — new tools for diagnosis and precision oncology

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The microbiome and cancer

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Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

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Data science and its relationship to big data and data-driven decision making

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The impact of diet and lifestyle on gut microbiota and human health

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Privacy in the age of medical big data

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Multi-Omics Factor Analysis—a framework for unsupervised integration of multi-omics data sets

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Deep learning for computational biology

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Antibiotics, birth mode, and diet shape microbiome maturation during early life

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Immune adaptations that maintain homeostasis with the intestinal microbiota

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Big data and machine learning algorithms for health-care delivery

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Cancer and the microbiota

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The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression

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The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy

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Human gut microbiome: Hopes, threats and promises

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The Integrative Human Microbiome Project

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Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

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Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations

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Persistent gut microbiota immaturity in malnourished Bangladeshi children

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Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

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Deep learning: new computational modelling techniques for genomics

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Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

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Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

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Guidelines for Developing and Reporting Machine Learning Predictive Models in Biomedical Research: A Multidisciplinary View

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Analysis of the microbiome: Advantages of whole genome shotgun versus 16S amplicon sequencing

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Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

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Gut microbiota modulation of chemotherapy efficacy and toxicity

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Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer

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Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

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Microbiota: a key orchestrator of cancer therapy

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Microbial Dysbiosis in Colorectal Cancer (CRC) Patients

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Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma

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Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation

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A community effort to assess and improve drug sensitivity prediction algorithms

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Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

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The Gut Microbiome Modulates Colon Tumorigenesis

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Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

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The oral microbiota in colorectal cancer is distinctive and predictive

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The International Cancer Genome Consortium Data Portal

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How Machine Learning Will Transform Biomedicine

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