The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Late onset of obesity in male androgen receptor-deficient (AR KO) mice
Open accessAbstract
An androgen receptor (AR) null mutant mice line was generated by means of a Cre-lox P system. The male (AR(L-/Y)) (KO) mice exhibited typical features of testicular feminization mutant (Tfm) disease in external reproductive organs with growth retardation. The growth curve of the male AR KO mice was similar to that of the wild-type female littermates until the 10th week of age, but thereafter a drastic increase in the growth was observed with development of obesity. Clear increase in the wet weights of white adipose tissues, but not of brown adipose tissue, was found in the 30-week-old male AR KO mice. However, no significant alteration in serum lipid parameters and food intake was observed. Thus, the present results suggest that AR may serve as a negative regulator of adipose development in adult males.
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Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90199-x · Cited by 6,964
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Biological Actions of Androgens
MOORADIAN, A. D., MORLEY, J. E., & KORENMAN, S. G. (1987) · Endocrine Reviews · doi:10.1210/edrv-8-1-1 · Cited by 1,080
The role of androgens in male gender role behavior
Wilson, J. D. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.5.0377 · Cited by 172
Cited by
Direct effects of sex steroid hormones on adipose tissues and obesity
Mayes, J. S., & Watson, G. H. (2004) · Obesity Reviews · doi:10.1111/j.1467-789x.2004.00152.x · Cited by 508
Kelly, D. M., & Jones, T. H. (2015) · Obesity Reviews · doi:10.1111/obr.12282 · Cited by 487
Obesity and androgens: facts and perspectives
Pasquali, R. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.10.054 · Cited by 469
Low Testosterone in Men with Type 2 Diabetes: Significance and Treatment
Grossmann, M. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0118 · Cited by 350
Mauvais-Jarvis, F. (2011) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2010.10.002 · Cited by 335
Metadata
- Authors
- Sato, T., Matsumoto, T., Yamada, T., Watanabe, T., Kawano, H., & Kato, S.
- Venue
- Biochemical and Biophysical Research Communications
- Publisher
- Elsevier BV
- Published
- 2003-01
- Volume
- 300
- Issue
- 1
- Pages
- 167-171
- ISSN
- 0006-291X (ISSN-L)
- OpenAlex
- W2069551953
- Cited by
- 196
- References
- 4
- FWCI
- 3.98
- Type
- journal article
- Language
- en
- Open access
- green
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- Sato, T., Matsumoto, T., Yamada, T., Watanabe, T., Kawano, H., & Kato, S. (2003). Late onset of obesity in male androgen receptor-deficient (AR KO) mice. Biochemical and Biophysical Research Communications. https://doi.org/10.1016/s0006-291x(02)02774-2
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