The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Pilot study of secondary prevention of posttraumatic stress disorder with propranolol
Abstract
Background Preclinical considerations suggest that treatment with a beta-adrenergic blocker following an acute psychologically traumatic event may reduce subsequent posttraumatic stress disorder (PTSD) symptoms. This pilot study addressed this hypothesis. Methods Patients were randomized to begin, within 6 hours of the event, a 10-day course of double-blind propranolol (n = 18) versus placebo (n = 23) 40 mg four times daily. Results The mean (SD) 1-month Clinician-Administered PTSD Scale (CAPS) score of 11 propranolol completers was 27.6 (15.7), with one outlier 5.2 SDs above the others' mean, and of 20 placebo completers, 35.5 (21.5), t = 1.1, df = 29, p =.15. Two propranolol patients' scores fell above, and nine below, the placebo group's median, p =.03 (sign test). Zero of eight propranolol, but six of 14 placebo, patients were physiologic responders during script-driven imagery of the traumatic event when tested 3 months afterward, p =.04 (all p values one-tailed). Conclusions These pilot results suggest that acute, posttrauma propranolol may have a preventive effect on subsequent PTSD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The evidence is inconclusive and so it is not possible to determine if there is a clinically important difference between propranolol and placebo on reducing the likelihood of having a PTSD diagnosis at 1 month (k=1; n=41; RR=1.14, 95% CI 0.55 to 2.35).”
From Resolution of flashbacks of PTSD with propranolol: A case report (2016) · cites this paper as [18]
In the citing paper
“There is limited evidence suggesting a difference favouring placebo over propranolol on reducing the likelihood of having a PTSD diagnosis at 3 months' follow-up (k=1; n=41; RR=1.28, 95% CI 0.69 to 2.38).18”
From Resolution of flashbacks of PTSD with propranolol: A case report (2016) · cites this paper as [18]
In the citing paper
“Beneficial effects of combining propranolol with trauma reactivation have been reported in a recent small randomised controlled trial (Brunet et al., 2018) as well as in three earlier pilot studies (Brunet et al., 2008;Pitman et al., 2002;Vaiva et al., 2003); however, negative outcomes have also been reported (Hoge et al., 2012;Wood et al., 2015).”
From Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders (2019) · cites this paper as Pitman et al., 2002
In the citing paper
“administration of propranolol (a beta-adrenergic antagonist) in the hours after trauma exposure limits subsequent reactivity to reminders 68”
From Post‐traumatic stress disorder: a state‐of‐the‐art review of evidence and challenges (2019) · cites this paper as [68]
In the citing paper
“As noted above, the initial trial of propranolol found that it resulted in reduced subsequent reactivity to trauma reminders, even though it did not reduce the severity of PTSD 68 .”
From Post‐traumatic stress disorder: a state‐of‐the‐art review of evidence and challenges (2019) · cites this paper as [68]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The development of a Clinician-Administered PTSD Scale
Blake, D. D., Weathers, F. W., Nagy, L. M., Kaloupek, D. G., Gusman, F. D., Charney, D. S., & Keane, T. M. (1995) · Journal of Traumatic Stress · doi:10.1002/jts.2490080106 · Cited by 5,024
β-Adrenergic activation and memory for emotional events
Cahill, L., Prins, B., Weber, M., & McGaugh, J. L. (1994) · Nature · doi:10.1038/371702a0 · Cited by 1,271
Self-citationNeural Correlates of Motor Memory Consolidation
Shadmehr, R., & Holcomb, H. H. (1997) · Science · doi:10.1126/science.277.5327.821 · Cited by 1,022
Psychophysiologic assessment of posttraumatic stress disorder imagery in Vietnam combat veterans
Pitman, R. K. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800230050009 · Cited by 758
Self-citationPost-traumatic stress disorder, hormones, and memory.
Pitman, R. (1989) · Biological Psychiatry · doi:10.1016/0006-3223(89)90033-4 · Cited by 447
Self-citationvan Stegeren, A. H., Everaerd, W., Cahill, L., McGaugh, J. L., & Gooren, L. J. G. (1998) · Psychopharmacology · doi:10.1007/s002130050675 · Cited by 230
Self-citationSignificance and Remembrance: The Role of Neuromodulatory Systems
McGaugh, J. L. (1990) · Psychological Science · doi:10.1111/j.1467-9280.1990.tb00060.x · Cited by 140
Impaired Memory Consolidation in Rats Produced with β-Adrenergic Blockade
Cahill, L. F., Pham, C. A., & Setlow, B. (2000) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1999.3950 · Cited by 124
Self-citationStress‐Activated Hormonal Systems and the Regulation of Memory Storage a
Roozendaal, B., Quirarte, G. L., & McGaugh, J. L. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb48284.x · Cited by 95
Cited by
Sorted by citations
Items 201–300 of 961
Liberzon, I., King, A. P. J., Ressler, K. J., Almli, L. M., Zhang, P., Ma, S. T., Cohen, G. H., Tamburrino, M., Calabrese, J. R., & Galea, S. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.999 · Cited by 88
Stoddard, F. J., Luthra, R., Sorrentino, E. A., Saxe, G., Drake, J., Chang, Y., Levine, J. B., Chedekel, D. S., & Sheridan, R. L. (2011) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2010.0133 · Cited by 85
Barsegyan, A., McGaugh, J. L., & Roozendaal, B. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00160 · Cited by 84
Zatzick, D., Russo, J. E., Pitman, R. K., Rivara, F. P., Jurkovich, G. J., & Roy‐Byrne, P. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.005 · Cited by 84
Self-citationFoa, E. B., Cahill, S. P., Boscarino, J. A., Hobfoll, S. E., Lahad, M., McNally, R. J., & Solomon, Z. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300815 · Cited by 85
Effects of single-prolonged stress on neurons and their afferent inputs in the amygdala
Cui, H., Sakamoto, H., Higashi, S., & Kawata, M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.12.028 · Cited by 88
Increased Skin Conductance Response in the Immediate Aftermath of Trauma Predicts PTSD Risk
Hinrichs, R. C., van Rooij, S. J. H., Michopoulos, V., Schultebraucks, K., Winters, S., Maples‐Keller, J. L., Rothbaum, A. O., Stevens, J. S., Galatzer‐Levy, I. R., Rothbaum, B. O., et al. (2019) · Chronic Stress · doi:10.1177/2470547019844441 · Cited by 88
Pharmacologic treatment of acute and chronic stress following trauma: 2006.
Davidson, J. R. T. (2006) · PubMed · Cited by 82
Zatzick, D., & Roy‐Byrne, P. (2006) · Psychiatric Services · doi:10.1176/appi.ps.57.12.1726 · Cited by 82
Matar, M. A., Cohen, H., Kaplan, Z., & Zohar, J. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301132 · Cited by 81
Post-traumatic stress disorder, resilience and vulnerability
Ahmed, A. S. (2007) · Advances in Psychiatric Treatment · doi:10.1192/apt.bp.106.003236 · Cited by 81
Glucocorticoid-induced enhancement of extinction—from animal models to clinical trials
de Quervain, D. J. ‐., Wolf, O. T., & Roozendaal, B. (2019) · Psychopharmacology · doi:10.1007/s00213-018-5116-0 · Cited by 82
Langley, A., & Pope, E. (2014) · British Journal of Dermatology · doi:10.1111/bjd.13379 · Cited by 78
Critical brain circuits at the intersection between stress and learning
Bangasser, D. A., & Shors, T. J. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.02.002 · Cited by 83
The Normativity of Memory Modification
Liao, S. M., & Sandberg, A. (2008) · Neuroethics · doi:10.1007/s12152-008-9009-5 · Cited by 84
Diagnosis and management of post-traumatic stress disorder.
Grinage, B. D. (2003) · PubMed · Cited by 78
Kroes, M., Strange, B., & Dolan, R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5469-09.2010 · Cited by 86
Krystal, J. H., Tolin, D. F., Sanacora, G., Castner, S. A., Williams, G. V., Aikins, D. E., Hoffman, R. E., & D'Souza, D. C. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2009.05.002 · Cited by 76
Propranolol does not reduce risk for acute stress disorder in pediatric burn trauma
Sharp, S., Thomas, C., Rosenberg, L., Rosenberg, M., & Meyer, W. (2010) · Journal of Trauma: Injury, Infection & Critical Care · doi:10.1097/ta.0b013e3181a8b326 · Cited by 76
Bajor, L. A., Ticlea, A. N., & Osser, D. N. (2011) · Harvard Review of Psychiatry · doi:10.3109/10673229.2011.614483 · Cited by 76
Villain, H., Benkahoul, A., Drougard, A., Lafragette, M., Muzotte, E., Pech, S., Bui, É., Brunet, A., Birmes, P. J., & Roullet, P. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00049 · Cited by 82
The role of basal forebrain cholinergic neurons in fear and extinction memory
Knox, D. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.06.001 · Cited by 81
Assessment and Treatment of Combat-Related PTSD in Returning War Veterans
Peterson, A. L., Luethcke, C. A., Borah, E. V., Borah, A. M., & Young‐McCaughan, S. (2011) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-011-9238-3 · Cited by 84
Neuroscience, Ethics, and National Security: The State of the Art
Tennison, M. N., & Moreno, J. D. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001289 · Cited by 75
Post-traumatic stress disorder in somatic disease: lessons from critically ill patients.
Schelling, G. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(07)67016-2 · Cited by 68
Watson, P., & Shalev, A. Y. (2005) · CNS Spectrums · doi:10.1017/s1092852900019465 · Cited by 74
Matar, M. A., Zohar, J., Kaplan, Z., & Cohen, H. (2009) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2008.12.004 · Cited by 74
van Marle, H. J. F. (2015) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v6.27633 · Cited by 84
Pharmacotherapy for post traumatic stress disorder (PTSD)
Williams, T., Phillips, N. J., Stein, D. J., & Ipser, J. C. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002795.pub3 · Cited by 96
Yang, Y.-L., Chao, P.-K., Ro, L., Wo, Y., & Lu, K.-T. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301215 · Cited by 79
Zoladz, P. R., Fleshner, M., & Diamond, D. M. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.01.001 · Cited by 79
Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)
Amos, T., Stein, D. J., & Ipser, J. C. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006239.pub2 · Cited by 169
ROBINSON, M., & Franklin, K. B. J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.05.023 · Cited by 72
Feldner, M. T., Zvolensky, M. J., Schmidt, N. B., & Smith, R. C. (2007) · Depression and Anxiety · doi:10.1002/da.20281 · Cited by 78
Orr, S., Milad, M., Metzger, L., Lasko, N., Gilbertson, M., & Pitman, R. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.05.001 · Cited by 63
Self-citationAdamec, R. E., Blundell, J. J., & Burton, P. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2003.09.017 · Cited by 71
Neuropsychiatric Consequences of Lipophilic Beta-Blockers
Cojocariu, S. A., Maștaleru, A., Sascău, R. A., Stătescu, C., Mitu, F., & Leon, M. M. (2021) · Medicina · doi:10.3390/medicina57020155 · Cited by 75
Single-session early psychological interventions following traumatic events
Bisson, J. I. (2003) · Clinical Psychology Review · doi:10.1016/s0272-7358(03)00034-5 · Cited by 70
Evidence-Based Treatment of Post-Traumatic Stress Disorder
Difede, J., Olden, M., & Cukor, J. (2014) · Annual Review of Medicine · doi:10.1146/annurev-med-051812-145438 · Cited by 70
Treatment-refractory posttraumatic stress disorder (TRPTSD): a review and framework for the future
Koek, R. J., Schwartz, H. N., Scully, S., Langevin, J., Spangler, S. L., Korotinsky, A., Jou, K., & Leuchter, A. F. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.01.015 · Cited by 74
β-Arrestin–biased signaling mediates memory reconsolidation
Liu, X., Ma, L., Li, H. H., Huang, B., Li, Y. X., Tao, Y. Z., & Ma, L. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421758112 · Cited by 69
Bracha, H. S., Garcia-Rill, E., Mrak, R. E., & Skinner, R. (2005) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.17.4.503 · Cited by 71
An Evidence-Based Review of Early Intervention and Prevention of Posttraumatic Stress Disorder
Birur, B., Moore, N. C., & Davis, L. L. (2016) · Community Mental Health Journal · doi:10.1007/s10597-016-0047-x · Cited by 69
Taylor, F., & Cahill, L. F. (2002) · Journal of Traumatic Stress · doi:10.1023/a:1020145610914 · Cited by 68
Self-citationRajbhandari, A. K., Baldo, B. A., & Bakshi, V. P. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.5080-14.2015 · Cited by 68
Nixon, R. D. V., Nehmy, T. J., Ellis, A. A., Ball, S.-A., Menne, A., & McKinnon, A. (2010) · Behaviour Research and Therapy · doi:10.1016/j.brat.2010.05.002 · Cited by 67
Haas, B. W., & Canli, T. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.10.014 · Cited by 69
Adamec, R. E., Blundell, J. J., & Burton, P. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.06.026 · Cited by 66
Protein synthesis and the mechanisms of lasting change in anxiety induced by severe stress
Adamec, R. E., Strasser, K. J., BLUNDELL, J., Burton, P., & MCKAY, D. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.09.019 · Cited by 67
McCleery, J. M., & Harvey, A. G. (2004) · Journal of Traumatic Stress · doi:10.1007/s10960-004-5797-5 · Cited by 70
Maddox, S. A., Watts, C. S., Doyère, V., & Schafe, G. E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054463 · Cited by 67
Schiff, H. C., Johansen, J. P., Hou, M., Bush, D. E. A., Smith, E. K., Klein, J. E., LeDoux, J. E., & Sears, R. M. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.238 · Cited by 67
Memory as a new therapeutic target
Nader, K., Hardt, O. M., & Lanius, R. A. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.4/knader · Cited by 67
Olfactory fear conditioning paradigm in rats: Effects of midazolam, propranolol or scopolamine
Kroon, J. A. V., & Carobrez, A. P. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.10.007 · Cited by 65
Neuroimaging Techniques for Memory Detection: Scientific, Ethical, and Legal Issues
Meegan, D. V. (2008) · The American Journal of Bioethics · doi:10.1080/15265160701842007 · Cited by 65
Performance-Enhancing Technologies and Moral Responsibility in the Military
Wolfendale, J. (2008) · The American Journal of Bioethics · doi:10.1080/15265160802014969 · Cited by 64
The Immediate Response to Disaster: Guidelines for Adult Psychological First Aid.
Young, B. H. (2006) · Cited by 64
Harnett, N. G., van Rooij, S. J. H., Ely, T. D., Lebois, L. A. M., Murty, V. P., Jovanović, T., Hill, S. B., Dumornay, N. M., Merker, J. B., Bruce, S. E., et al. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-020-00946-8 · Cited by 67
Pharmacotherapy of Post-Traumatic Stress Disorder
Ravindran, L. N., & Stein, M. B. (2009) · Current topics in behavioral neurosciences · doi:10.1007/7854_2009_15 · Cited by 64
Neural long-term effects of emotion regulation on episodic memory processes
Erk, S., von Kalckreuth, A., & Walter, H. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.11.022 · Cited by 71
Psychopharmacology of anxiety disorders
Cassano, G. B., Rossi, N. B., & Pini, S. (2002) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2002.4.3/gcassano · Cited by 66
Physical, Cognitive, and Psychological Disability Following Critical Illness: What Is the Risk?
Erb, C. T., Jackson, J. C., & Jutte, J. E. (2015) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0035-1566002 · Cited by 68
Elsey, J. W. B., & Kindt, M. (2016) · AJOB Neuroscience · doi:10.1080/21507740.2016.1218377 · Cited by 66
Cohen, S., Kozlovsky, N., Matar, M. A., Kaplan, Z., Zohar, J., & Cohen, H. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.94 · Cited by 62
A brainstem-central amygdala circuit underlies defensive responses to learned threats
Gu, Y., Piper, W. T., Branigan, L., Vazey, E. M., Aston‐Jones, G., Lin, L., LeDoux, J. E., & Sears, R. M. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0599-6 · Cited by 65
Rasmusson, A. M., & Pineles, S. L. (2018) · Current Psychiatry Reports · doi:10.1007/s11920-018-0908-9 · Cited by 63
Stein, D. J., Davidson, J. R. T., Seedat, S., & Beebe, K. L. (2003) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.4.10.1829 · Cited by 61
Information Processing Bias in Post-traumatic Stress Disorder
Weber, D. L. (2008) · The Open Neuroimaging Journal · doi:10.2174/1874440000802010029 · Cited by 66
Psychopharmacological Issues in the Treatment of TBI and PTSD
McAllister, T. W. (2009) · The Clinical Neuropsychologist · doi:10.1080/13854040903277289 · Cited by 62
Early intervention for post‐traumatic stress disorder
Bryant, R. A. (2007) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2007.00006.x · Cited by 58
Are You Morally Modified?: The Moral Effects of Widely Used Pharmaceuticals
Levy, N. L., Douglas, T., Kahane, G., Terbeck, S., Cowen, P. J., Hewstone, M., & Savulescu, J. (2014) · Philosophy, psychiatry & psychology · doi:10.1353/ppp.2014.0023 · Cited by 62
Post-traumatic stress disorder
Bisson, J. I. (2007) · Occupational Medicine · doi:10.1093/occmed/kqm069 · Cited by 58
Nugent, N. R., Christopher, N. C., & Delahanty, D. L. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01648.x · Cited by 58
Matsuoka, Y., Nishi, D., Nakajima, S., Kim, Y., Homma, M., & Otomo, Y. (2008) · Critical Care Medicine · doi:10.1097/01.ccm.0000291650.70816.d6 · Cited by 58
Five Essential Elements of Immediate and Mid–Term Mass Trauma Intervention: Empirical Evidence
Hobfoll, S. E., Watson, P., Bell, C. C., Bryant, R. A., Brymer, M. J., Friedman, M. J., Friedman, M., Gersons, B. P. R., de Jong, J. T. V. M., Layne, C. M., et al. (2021) · Psychiatry · doi:10.1080/00332747.2021.2005387 · Cited by 66
van Gelderen, M. J., Nijdam, M. J., & Vermetten, E. H. G. J. M. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00176 · Cited by 58
Kozarić‐Kovačić, D., & Pivac, N. (2006) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145706006596 · Cited by 56
Pharmacological enhancement of fear reduction: preclinical models
Graham, B. M., Langton, J. M., & Richardson, R. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.01175.x · Cited by 57
Bryant, R. A. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.002 · Cited by 55
Combining pharmacotherapy with cognitive behavioral therapy: Traditional and new approaches
Davis, M., Barad, M., Otto, M. W., & Southwick, S. (2006) · Journal of Traumatic Stress · doi:10.1002/jts.20149 · Cited by 55
Advances in the treatment of anxiety: Targeting glutamate
Simon, A. B., & Gorman, J. M. (2006) · NeuroRx · doi:10.1016/j.nurx.2005.12.005 · Cited by 58
Toward early pharmacological posttraumatic stress intervention
Morgan, C. A., Krystal, J. H., & Southwick, S. M. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00116-1 · Cited by 55
Prevention of posttraumatic stress disorder with propranolol: A meta-analytic review
Argolo, F. C., Cavalcanti-Ribeiro, P., Netto, L. R., & Quarantini, L. C. (2015) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2015.04.006 · Cited by 53
Role of NMDA receptors in the syndrome of behavioral changes produced by predator stress
Blundell, J. J., Adamec, R. E., & Burton, P. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.07.012 · Cited by 55
Shalev, A. Y. (2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511500008.015 · Cited by 53
Brietzke, E. M., Mansur, R. B., Soczynska, J. K., Powell, A. M., & McIntyre, R. S. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.05.004 · Cited by 56
Videlock, E. J., Peleg, T., Segman, R. H., Yehuda, R., Pitman, R. K., & Shalev, A. Y. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707008139 · Cited by 55
Self-citationDonovan, E. L. (2010) · Perspectives in biology and medicine · doi:10.1353/pbm.0.0140 · Cited by 51
Targeting memory processes with drugs to prevent or cure PTSD
Cain, C. K., Maynard, G. D., & Kehne, J. H. (2012) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2012.704020 · Cited by 50
Preventing Post Traumatic Stress Disorder: Are Drugs the Answer?
Fletcher, S. L., Creamer, M. C., & Forbes, D. (2010) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2010.509858 · Cited by 51
Bryant, R. A. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.101981 · Cited by 65
Tonic and Phasic Heart Rate as Predictors of Posttraumatic Stress Disorder
O'Donnell, M. L., Creamer, M. C., Elliott, P., & Bryant, R. A. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3180417d04 · Cited by 51
Decision‐making capacity and disaster research
Rosenstein, D. L. (2004) · Journal of Traumatic Stress · doi:10.1023/b:jots.0000048950.36359.a2 · Cited by 51
Schwabe, L., Nader, K., & Pruessner, J. C. (2012) · Biological Psychology · doi:10.1016/j.biopsycho.2012.10.003 · Cited by 54
Hypnosis and the Treatment of Posttraumatic Conditions: An Evidence-Based Approach
Lynn, S. J., & Cardeña, E. (2007) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207140601177905 · Cited by 51
Bryant, R. A., Brooks, R., Silove, D. M., Creamer, M. C., O'Donnell, M. L., & McFARLANE, A. C. (2011) · Behaviour Research and Therapy · doi:10.1016/j.brat.2011.03.003 · Cited by 50
Targeting memory reconsolidation to prevent the return of fear in patients with fear of flying
Maples‐Keller, J. L., Price, M., Jovanović, T., Norrholm, S. D., Odenat, L., Post, L. M., Zwiebach, L. C., Breazeale, K. G., Gross, R. E., Kim, S.-J., et al. (2017) · Depression and Anxiety · doi:10.1002/da.22626 · Cited by 55
Hauer, D., Kaufmann, I., Strewe, C., Briegel, I., Campolongo, P., & Schelling, G. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.10.003 · Cited by 49
Tollenaar, M. S., Elzinga, B. M., Spinhoven, P., & Everaerd, W. T. A. M. (2009) · Psychopharmacology · doi:10.1007/s00213-008-1427-x · Cited by 49
Pradhan, B., Wainer, I. W., Moaddel, R., Torjman, M. C., Goldberg, M., Sabia, M., Parikh, T., & Pumariega, A. (2017) · Asia Pacific Journal of Clinical Trials Nervous System Diseases · doi:10.4103/2542-3932.211589 · Cited by 52
Metadata
- Authors
- Pitman, R. K., Sanders, K. M., Zusman, R. M., Healy, A. R., Cheema, F., Lasko, N. B., Cahill, L., & Orr, S. P.
- Affiliations
- Harvard University (US)
- University of California, Irvine (US)
- Corresponding author
- Pitman, Roger K.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2002-01
- Volume
- 51
- Issue
- 2
- Pages
- 189-192
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2026396276
- Cited by
- 964
- References
- 11
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 11 · 2023: 16 · 2022: 21 · 2021: 32 · 2020: 22 · 2019: 41 · 2018: 65 · 2017: 26 · 2016: 30 · 2015: 51 · 2014: 51 · 2013: 49 · 2012: 53
- FWCI
- 54.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh058671-02)
- National Institute of Mental Health (MH58671)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Keywords
- post-traumatic stress disorder, propranolol, beta-blockers, secondary prevention, early intervention, script-driven imagery, physiological reactivity, Clinician-Administered PTSD Scale
- MeSH terms
- Accidents, Traffic, Adult, Arousal, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Emergency Service, Hospital, Female, Humans, Male, Pilot Projects, Propranolol, Stress Disorders, Post-Traumatic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
