The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Pilot study of secondary prevention of posttraumatic stress disorder with propranolol
Abstract
Background Preclinical considerations suggest that treatment with a beta-adrenergic blocker following an acute psychologically traumatic event may reduce subsequent posttraumatic stress disorder (PTSD) symptoms. This pilot study addressed this hypothesis. Methods Patients were randomized to begin, within 6 hours of the event, a 10-day course of double-blind propranolol (n = 18) versus placebo (n = 23) 40 mg four times daily. Results The mean (SD) 1-month Clinician-Administered PTSD Scale (CAPS) score of 11 propranolol completers was 27.6 (15.7), with one outlier 5.2 SDs above the others' mean, and of 20 placebo completers, 35.5 (21.5), t = 1.1, df = 29, p =.15. Two propranolol patients' scores fell above, and nine below, the placebo group's median, p =.03 (sign test). Zero of eight propranolol, but six of 14 placebo, patients were physiologic responders during script-driven imagery of the traumatic event when tested 3 months afterward, p =.04 (all p values one-tailed). Conclusions These pilot results suggest that acute, posttrauma propranolol may have a preventive effect on subsequent PTSD.
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“The evidence is inconclusive and so it is not possible to determine if there is a clinically important difference between propranolol and placebo on reducing the likelihood of having a PTSD diagnosis at 1 month (k=1; n=41; RR=1.14, 95% CI 0.55 to 2.35).”
From Resolution of flashbacks of PTSD with propranolol: A case report (2016) · cites this paper as [18]
In the citing paper
“There is limited evidence suggesting a difference favouring placebo over propranolol on reducing the likelihood of having a PTSD diagnosis at 3 months' follow-up (k=1; n=41; RR=1.28, 95% CI 0.69 to 2.38).18”
From Resolution of flashbacks of PTSD with propranolol: A case report (2016) · cites this paper as [18]
In the citing paper
“Beneficial effects of combining propranolol with trauma reactivation have been reported in a recent small randomised controlled trial (Brunet et al., 2018) as well as in three earlier pilot studies (Brunet et al., 2008;Pitman et al., 2002;Vaiva et al., 2003); however, negative outcomes have also been reported (Hoge et al., 2012;Wood et al., 2015).”
From Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders (2019) · cites this paper as Pitman et al., 2002
In the citing paper
“administration of propranolol (a beta-adrenergic antagonist) in the hours after trauma exposure limits subsequent reactivity to reminders 68”
From Post‐traumatic stress disorder: a state‐of‐the‐art review of evidence and challenges (2019) · cites this paper as [68]
In the citing paper
“As noted above, the initial trial of propranolol found that it resulted in reduced subsequent reactivity to trauma reminders, even though it did not reduce the severity of PTSD 68 .”
From Post‐traumatic stress disorder: a state‐of‐the‐art review of evidence and challenges (2019) · cites this paper as [68]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The development of a Clinician-Administered PTSD Scale
Blake, D. D., Weathers, F. W., Nagy, L. M., Kaloupek, D. G., Gusman, F. D., Charney, D. S., & Keane, T. M. (1995) · Journal of Traumatic Stress · doi:10.1002/jts.2490080106 · Cited by 5,024
β-Adrenergic activation and memory for emotional events
Cahill, L., Prins, B., Weber, M., & McGaugh, J. L. (1994) · Nature · doi:10.1038/371702a0 · Cited by 1,271
Self-citationNeural Correlates of Motor Memory Consolidation
Shadmehr, R., & Holcomb, H. H. (1997) · Science · doi:10.1126/science.277.5327.821 · Cited by 1,022
Psychophysiologic assessment of posttraumatic stress disorder imagery in Vietnam combat veterans
Pitman, R. K. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800230050009 · Cited by 758
Self-citationPost-traumatic stress disorder, hormones, and memory.
Pitman, R. (1989) · Biological Psychiatry · doi:10.1016/0006-3223(89)90033-4 · Cited by 447
Self-citationvan Stegeren, A. H., Everaerd, W., Cahill, L., McGaugh, J. L., & Gooren, L. J. G. (1998) · Psychopharmacology · doi:10.1007/s002130050675 · Cited by 230
Self-citationSignificance and Remembrance: The Role of Neuromodulatory Systems
McGaugh, J. L. (1990) · Psychological Science · doi:10.1111/j.1467-9280.1990.tb00060.x · Cited by 140
Impaired Memory Consolidation in Rats Produced with β-Adrenergic Blockade
Cahill, L. F., Pham, C. A., & Setlow, B. (2000) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1999.3950 · Cited by 124
Self-citationStress‐Activated Hormonal Systems and the Regulation of Memory Storage a
Roozendaal, B., Quirarte, G. L., & McGaugh, J. L. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb48284.x · Cited by 95
Cited by
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Items 301–400 of 961
Hourani, L. L., Hubal, R. C., & Strange, L. B. (2011) · Military Medicine · doi:10.7205/milmed-d-09-00227 · Cited by 49
Relaxing music counters heightened consolidation of emotional memory
Rickard, N. S., Wong, W. W., & Velik, L. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.12.005 · Cited by 48
Weymar, M., Löw, A., Modeß, C., Engel, G., Gründling, M., Petersmann, A., Siegmund, W., & Hamm, A. O. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.10.025 · Cited by 47
Szeleszczuk, Ł., & Frączkowski, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710099 · Cited by 46
Adrenal Stress Hormones and Enhanced Memory for Emotionally Arousing Experiences
McIntyre, C. K., & Roozendaal, B. (2007) · Frontiers in neuroscience · doi:10.1201/9781420008418.ch13 · Cited by 46
Shipherd, J. C., & Salters‐Pedneault, K. (2008) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2008.01.003 · Cited by 48
Lanius, R. A., Brewin, C. R., Bremner, J. D., Daniels, J. K., Friedman, M. J., Liberzon, I., McFARLANE, A. C., Schnurr, P. P., Shin, L. M., Stein, M. B., et al. (2010) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.090047 · Cited by 45
Extinction: Behavioral Mechanisms and Their Implications
Bouton, M. E., & Woods, A. M. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00088-7 · Cited by 46
Corchs, F., Nutt, D., Hood, S. D., & Bernik, M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.01.031 · Cited by 46
The Impact of Terrorism on Brain, and Behavior: What We Know and What We Need to Know
Yehuda, R., & Hyman, S. E. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300817 · Cited by 45
Risperidone Treatment of Preschool Children with Thermal Burns and Acute Stress Disorder
Meighen, K. G., Hines, L., & Lagges, A. M. (2007) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2006.0121 · Cited by 46
The Role of the Amygdala in Anxiety Disorders
Gina, L., Andrew, M., Jamie, L. A., & Michael, J. (2012) · InTech eBooks · doi:10.5772/50323 · Cited by 48
Biological and clinical framework for posttraumatic stress disorder
Vermetten, E. H. G. J. M., & Lanius, R. A. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52002-9.00018-8 · Cited by 50
Stress modulation of reconsolidation
Akirav, I., & Maroun, M. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2887-6 · Cited by 46
Spironolactone and low-dose dexamethasone enhance extinction of contextual fear conditioning
Ninomiya, E. M., Martynhak, B. J., Zanoveli, J. M., Correia, D., Cunha, C. D., & Andreatini, R. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.025 · Cited by 45
Five Essential Elements of Immediate and Mid-Term Mass Trauma Intervention: Empirical Evidence
Hobfoll, S. E., Watson, P., Bell, C. C., Bryant, R. A., Brymer, M. J., Friedman, M. J., Friedman, M., Gersons, B. P. R., de Jong, J. T. V. M., Layne, C. M., et al. (2009) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.7.2.foc221 · Cited by 48
Two weeks of pretreatment with escitalopram facilitates extinction learning in healthy individuals
Bui, E., Orr, S. P., Jacoby, R. J., Keshaviah, A., LeBlanc, N. J., Milad, M. R., Pollack, M. H., & Simon, N. M. (2013) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.2330 · Cited by 42
Self-citationClinical Manifestations of Body Memories: The Impact of Past Bodily Experiences on Mental Health
Gentsch, A., & Kuehn, E. (2022) · Brain Sciences · doi:10.3390/brainsci12050594 · Cited by 59
Oei, N. Y. L., Tollenaar, M. S., Elzinga, B. M., & Spinhoven, P. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.12.005 · Cited by 44
Friedman, M. J. (2012) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780195399066.013.0036 · Cited by 45
Advances in pharmacotherapy for pediatric anxiety disorders
Rynn, M. A., Puliafico, A. C., Heleniak, C. M., Rikhi, P., Ghalib, K., & Vidair, H. B. (2011) · Depression and Anxiety · doi:10.1002/da.20769 · Cited by 45
TREATMENT PREFERENCES AND DETERMINANTS IN VICTIMS OF SEXUAL AND PHYSICAL ASSAULT
Roy‐Byrne, P., Berliner, L., RUSSO, J., Zatzick, D., & Pitman, R. K. (2003) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000055343.62310.73 · Cited by 44
Self-citationExposure to extreme stress impairs contextual odour discrimination in an animal model of PTSD
Cohen, H., Liberzon, I., & Richter‐Levin, G. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114570800919x · Cited by 44
Cosmetic neurology: the controversy over enhancing movement, mentation, and mood.
Dees, R. H. (2005) · PubMed · Cited by 44
Buckley, B., Nugent, N. R., Sledjeski, E. M., Raimonde, A. J., Spoonster, E., Bogart, L. M., & Delahanty, D. L. (2004) · Journal of Traumatic Stress · doi:10.1023/b:jots.0000038480.87290.4a · Cited by 43
Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice
Cavener, V. S., Gaulden, A. D., Pennipede, D., Jagasia, P., Uddin, J., Marnett, L. J., & Patel, S. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00479 · Cited by 43
Sakauye, K. M., Streim, J. E., Kennedy, G. J., Kirwin, P. D., Llorente, M. D., Schultz, S. K., & Srinivasan, S. (2009) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181b4bf20 · Cited by 43
The cognitive paradox in posttraumatic stress disorder: a hypothesis
van Praag, H. M. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.05.011 · Cited by 44
Bracha, H. S., Williams, A. E., Haynes, S. N., Kubany, E. S., Ralston, T. C., & Yamashita, J. M. (2004) · Annals of General Hospital Psychiatry · doi:10.1186/1475-2832-3-8 · Cited by 43
Attitudes Toward Cognitive Enhancement: The Role of Metaphor and Context
Conrad, E. C., Humphries, S. A., & Chatterjee, A. K. (2019) · AJOB Neuroscience · doi:10.1080/21507740.2019.1595771 · Cited by 42
Charney, D. S. (2003) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2003.5.3/dcharney · Cited by 42
Matsuoka, Y. (2011) · BioPsychoSocial Medicine · doi:10.1186/1751-0759-5-3 · Cited by 42
The role of cortisol in PTSD among women exposed to a trauma-related stressor
Stoppelbein, L., Greening, L., & Fite, P. J. (2011) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2011.12.004 · Cited by 47
PTSD and Chronic Pain: Cognitive-Behavioral Perspectives and Practical Implications
Asmundson, G. J. G., & Taylor, S. J. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-387-25610-5_13 · Cited by 40
Pharmacotherapy in post-traumatic stress disorder: evidence from randomized controlled trials.
Sullivan, G. M., & Neria, Y. (2009) · PubMed · Cited by 41
Adamec, R. E., Creamer, K., Bartoszyk, G. D., & Burton, P. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.09.017 · Cited by 41
Regulation of excitatory synapses and fearful memories by stress hormones
Krugers, H. J. (2011) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2011.00062 · Cited by 46
Krauseneck, T., Padberg, F., Roozendaal, B., Grathwohl, M., Weis, F. C., Hauer, D., Kaufmann, I., Schmoeckel, M., & Schelling, G. (2009) · Psychological Medicine · doi:10.1017/s0033291709990614 · Cited by 40
Post-traumatic stress disorder: emerging concepts of pharmacotherapy
Baker, D. G., Nievergelt, C. M., & Risbrough, V. B. (2009) · Expert Opinion on Emerging Drugs · doi:10.1517/14728210902972494 · Cited by 39
Terock, J., Hannemann, A., Janowitz, D., Freyberger, H. J., Felix, S. B., Dörr, M., Nauck, M. A., Völzke, H., & Grabe, H. J. (2018) · Psychological Medicine · doi:10.1017/s0033291718001496 · Cited by 41
Lovelock, D. F., & Deak, T. (2019) · Brain Research · doi:10.1016/j.brainres.2019.146392 · Cited by 41
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Ursano, R. J., Goldenberg, M., Zhang, L., Carlton, J. R., Fullerton, C. S., Li, H., Johnson, L. R., & Benedek, D. M. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05721.x · Cited by 39
The extinction of conditioned fear: structural and molecular basis and therapeutic use
Cammarota, M., Bevilaqua, L. R., Vianna, M. R. M. R., Medina, J. H., & Izquierdo, I. (2006) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462006005000022 · Cited by 42
Roy-Byrne, P., Russo, J., Michelson, E., Zatzick, D., Pitman, R., & Berliner, L. (2004) · Depression and Anxiety · doi:10.1002/da.10132 · Cited by 42
Self-citationPost-traumatic stress disorder: an evaluation of existing pharmacotherapies and new strategies
Zhang, W., & Davidson, J. R. T. (2007) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.8.12.1861 · Cited by 40
Noradrenergic blockade and numeric working memory in humans
Müller, U., Mottweiler, E., & Bublak, P. (2005) · Journal of Psychopharmacology · doi:10.1177/0269881105048888 · Cited by 40
Single dose propranolol does not affect physiologic or emotional reactivity to smoking cues
Pachas, G. N., Gilman, J. M., Orr, S. P., Hoeppner, B. B., Carlini, S. V., Loebl, T., Nino, J., Pitman, R. K., & Evins, A. E. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3797-6 · Cited by 42
Self-citationMatsumura, K., Noguchi, H., Nishi, D., Hamazaki, K., Hamazaki, T., & Matsuoka, Y. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.054 · Cited by 39
Bracha, H. S., Ralston, T. C., Williams, A. E., Yamashita, J. M., & Bracha, A. S. (2005) · CNS Spectrums · doi:10.1017/s109285290002263x · Cited by 39
Hruska, B., Cullen, P. K., & Delahanty, D. L. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.02.001 · Cited by 38
The warrior in the machine: neuroscience goes to war
Tracey, I., & Flower, R. (2014) · Nature reviews. Neuroscience · doi:10.1038/nrn3835 · Cited by 39
Rosenberg, L., Rosenberg, M., Sharp, S., THOMAS, C. R., Humphries, H. F., Holzer, C. E., Herndon, D. N., & Meyer, W. J. (2017) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2017.0073 · Cited by 38
Bolsoni, L. M., Crippa, J. A. S., Hallak, J. E. C., Guimarães, F. S., & Zuardi, A. W. (2022) · Psychopharmacology · doi:10.1007/s00213-021-06043-y · Cited by 41
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Mendelsohn, D. A., Lipsman, N., & Bernstein, M. (2010) · Journal of neurosurgery · doi:10.3171/2010.5.jns091896 · Cited by 37
Grissom, N. M., & Bhatnagar, S. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2010.12.049 · Cited by 37
Kleim, B., Wilhelm, F. H., Glucksman, E., & Ehlers, A. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181f8894b · Cited by 37
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Chatterjee, A. K. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-444-53501-6.00027-5 · Cited by 36
Spring, J. D., Wood, N. E., Mueller‐Pfeiffer, C., Milad, M. R., Pitman, R. K., & Orr, S. P. (2014) · Psychophysiology · doi:10.1111/psyp.12326 · Cited by 39
Self-citationBeta adrenergic blockade reduces utilitarian judgement
Terbeck, S., Kahane, G., Sarah, M., Julian, S., Levy, N. L., Hewstone, M., & Cowen, P. J. (2012) · Biological Psychology · doi:10.1016/j.biopsycho.2012.09.005 · Cited by 41
Kolber, A. J. (2008) · Neuroethics · doi:10.1007/s12152-008-9011-y · Cited by 36
Bolsoni, L. M., Crippa, J. A. S., Hallak, J. E. C., Guimarães, F. S., & Zuardi, A. W. (2022) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2021-2317 · Cited by 36
Pharmacologic Treatment of Panic Disorder
Stein, M. B., Steckler, T., Lightfoot, J., Hay, E., & Goddard, A. W. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2009_35 · Cited by 36
Psychophysiologic Reactivity: Implications for Conceptualizing PTSD
Orr, S. P., McNally, R. J., Rosen, G. M., & Shalev, A. Y. (2004) · Wiley eBooks · doi:10.1002/9780470713570.ch6 · Cited by 36
Self-citationGoode, T. D., Leong, K.-C., Goodman, J., Maren, S., & Packard, M. G. (2016) · Neurobiology of Stress · doi:10.1016/j.ynstr.2016.02.004 · Cited by 35
Beta‐blockers may reduce intrusive thoughts in newly diagnosed cancer patients
Lindgren, M. E., Fagundes, C. P., Alfano, C. M., Povoski, S. P., Agnese, D. M., Arnold, M. W., Farrar, W. B., Yee, L. D., Carson, W. E., Schmidt, C. R., et al. (2013) · Psycho-Oncology · doi:10.1002/pon.3233 · Cited by 35
Pharmacotherapy for Posttraumatic Stress Disorder: Empirical Review and Clinical Recommendations
Cooper, J. A., Carty, J., & Creamer, M. C. (2005) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2005.01651.x · Cited by 35
Kearns, M. L., & Engelhard, I. M. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00115 · Cited by 38
Easy to remember, difficult to forget: The development of fear regulation
Johnson, D. C., & Casey, B. J. (2014) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.07.006 · Cited by 37
Pathological Responses to Terrorism
Yehuda, R., Bryant, R. A., Marmar, C. R., & Zohar, J. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300816 · Cited by 36
Resick, P. A., Monson, C. M., & LoSavio, S. T. (2017) · Psychopathology · doi:10.1002/9781394258949.ch6 · Cited by 37
Brain Implants to Erase Memories
Glannon, W. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00584 · Cited by 33
Pharmacotherapy in the Aftermath of Trauma; Opportunities in the ‘Golden Hours’
Vermetten, E. H. G. J. M., Zhohar, J., & Krugers, H. J. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0455-y · Cited by 34
Bertolini, F., Robertson, L., Bisson, J. I., Meader, N., Churchill, R. C., Ostuzzi, G., Stein, D. J., Williams, T., & Barbui, C. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013443.pub2 · Cited by 38
Manion, S. T., Gamble, E. H., & Li, H. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.01.019 · Cited by 32
Kao, C. ‐., Stalla, G. K., Stalla, J., Wotjak, C. T., & Anderzhanova, E. A. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.12860 · Cited by 32
Asmundson, G. J. G., & Hadjistavropolous, H. D. (2006) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2005.03.001 · Cited by 32
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Dooley, T. P. (2015) · Mental Health in Family Medicine · doi:10.25149/1756-8358.1102013 · Cited by 32
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Drake, J. E., Stoddard, F. J., Murphy, J. M., Ronfeldt, H. M., Snidman, N. C., Kagan, J., Saxe, G., & Sheridan, R. L. (2006) · Journal of Burn Care & Research · doi:10.1097/01.bcr.0000202618.51001.69 · Cited by 32
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Sones, H. M., Thorp, S. R., & Raskind, M. A. (2011) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2010.11.001 · Cited by 31
Control of fear extinction by hypothalamic melanin-concentrating hormone–expressing neurons
Concetti, C., Bracey, E. F., Peleg‐Raibstein, D., & Burdakov, D. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2007993117 · Cited by 30
Brain dysfunction in critically ill patients--the intensive care unit and beyond.
Meyer, N. J., & Hall, J. B. (2006) · Critical Care · doi:10.1186/cc4980 · Cited by 31
Glannon, W. (2010) · Cambridge University Press eBooks · doi:10.1017/9781316443712 · Cited by 30
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Bryant, R. A. (2003) · CNS Spectrums · doi:10.1017/s1092852900008853 · Cited by 29
Karlović, D., Marušić, S., & Martinac, M. (2004) · Wiener klinische Wochenschrift · doi:10.1007/bf03040918 · Cited by 30
Depression and Anxiety in Children at the End of Life
Kersun, L. S., & Shemesh, E. (2007) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2007.06.003 · Cited by 33
An epidemiologic approach to the development of early trauma focused intervention
Zatzick, D., & Galea, S. (2007) · Journal of Traumatic Stress · doi:10.1002/jts.20256 · Cited by 31
Metabolic Enhancement of the Soldier Brain
Friedl, K. E., & Grate, S. J. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780190455132.003.0002 · Cited by 29
Bisson, J. I. (2010) · Taylor & Francis eBooks · doi:10.4324/9780203333754_chapter_4 · Cited by 29
Cohen, H., Kozlovsky, N., Matar, M. A., Kaplan, Z., & Zohar, J. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2009.12.006 · Cited by 29
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Fricchione, J. G., Greenberg, M. S., Spring, J. D., Wood, N. E., Mueller‐Pfeiffer, C., Milad, M. R., Pitman, R. K., & Orr, S. P. (2016) · Psychophysiology · doi:10.1111/psyp.12687 · Cited by 35
Self-citationStrawn, J. R., Ekhator, N. N., Horn, P. S., Baker, D. G., & Geracioti, T. D. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000138133.72365.45 · Cited by 30
The Sarin Gas Attacks on the Tokyo Subway - 10 years later/Lessons Learned.
Beaton, R. D., Stergachis, A. S., Oberle, M. W., Bridges, E. J., Nemuth, M., & Thomas, T. (2005) · Traumatology An International Journal · doi:10.1177/153476560501100205 · Cited by 29
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Concetti, C., Peleg-Raibstein, D., & Burdakov, D. (2023) · Function · doi:10.1093/function/zqad059 · Cited by 28
Sleep-dependent memory consolidation and its implications for psychiatry
Goerke, M., Müller, N. G., & Cohrs, S. (2015) · Journal of Neural Transmission · doi:10.1007/s00702-015-1476-3 · Cited by 31
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Sabé, M., Chen, C., El‐Hage, W., Leroy, A., Vaïva, G., Monari, S., Prémand, N., Bartolomei, J., Caiolo, S., Maercker, A. R. A., et al. (2023) · Current Neuropharmacology · doi:10.2174/1570159x22666230927143106 · Cited by 31
Adamec, R. E., HEAD, D. W., Soreq, H., & Blundell, J. J. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.12.023 · Cited by 28
Polta, S., Fenzl, T., Jakubcakova, V., Kimura, M., Yassouridis, A., & Wotjak, C. T. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00060 · Cited by 31
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Connor, K. M., & Butterfield, M. I. (2003) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.1.3.247 · Cited by 30
Metadata
- Authors
- Pitman, R. K., Sanders, K. M., Zusman, R. M., Healy, A. R., Cheema, F., Lasko, N. B., Cahill, L., & Orr, S. P.
- Affiliations
- Harvard University (US)
- University of California, Irvine (US)
- Corresponding author
- Pitman, Roger K.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2002-01
- Volume
- 51
- Issue
- 2
- Pages
- 189-192
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2026396276
- Cited by
- 964
- References
- 11
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 11 · 2023: 16 · 2022: 21 · 2021: 32 · 2020: 22 · 2019: 41 · 2018: 65 · 2017: 26 · 2016: 30 · 2015: 51 · 2014: 51 · 2013: 49 · 2012: 53
- FWCI
- 54.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh058671-02)
- National Institute of Mental Health (MH58671)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Keywords
- post-traumatic stress disorder, propranolol, beta-blockers, secondary prevention, early intervention, script-driven imagery, physiological reactivity, Clinician-Administered PTSD Scale
- MeSH terms
- Accidents, Traffic, Adult, Arousal, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Emergency Service, Hospital, Female, Humans, Male, Pilot Projects, Propranolol, Stress Disorders, Post-Traumatic
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