The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
The Saccharomyces cerevisiae CCH1 gene is involved in calcium influx and mating
Abstract
The yeast Saccharomyces cerevisiae gene CCH1 (ORF YGR217w) shows high homology with animal calcium channel α1‐subunit genes. Knock‐out mutants were constructed of Cch1 and of Mid1 which is known to mediate Ca 2+ influx in response to the α‐mating pheromone. Cch1 is involved in calcium influx and the late stage of the mating process. The cch1 mutant sensitivity against the α‐mating pheromone can be reduced by the addition of extra calcium. The product of this gene is likely to interact with the MID1 gene product in Ca influx or its control.
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“This is consistent with previous genetic data that demonstrated identical phenotypic defects of strains lacking either Mid1 or Cch1 including nonviability in low [Ca 2ϩ ] medium (7,11,15,20).”
From Cch1 Restores Intracellular Ca2+ in Fungal Cells during Endoplasmic Reticulum Stress (2010) · cites this paper as [11]
Citations
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[9] Gel electrophoresis of restriction fragments
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Cited by
Sorted by citations
Cell Wall Integrity Signaling in Saccharomyces cerevisiae
Levin, D. E. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.2.262-291.2005 · Cited by 1,136
“Cch1 is related to the 1 pore-forming subunit of L-type mammalian voltage-gated Ca(2) channels (86, 251).”
BackgroundBorkovich, K. A., Alex, L. A., Yarden, O., Freitag, M., Turner, G., Read, N. D., Seiler, S., Bell‐Pedersen, D., Paietta, J. V., Plesofsky, N. S., et al. (2004) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.68.1.1-108.2004 · Cited by 636
“Three new Ca2 channel proteins, which have close homologues to the three Ca2 channel proteins (Mid1p, Cch1p, and Yvc1p [238, 545, 583]) in S. cerevisiae, have been identified in Neurospora.”
BackgroundArabidopsis plasma membrane protein crucial for Ca 2+ influx and touch sensing in roots
Nakagawa, Y., Katagiri, T., Shinozaki, K., Qi, Z., Tatsumi, H., Furuichi, T., Kishigami, A., Sokabe, M., Kojima, I., Sato, S., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607703104 · Cited by 406
Calcium channels in higher plants
White, P. J. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00137-1 · Cited by 357
The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity
Thor, K., Jiang, S., Michard, E., George, J., Scherzer, S. H., Huang, S., Dindas, J., Derbyshire, P., Leitão, N., DeFalco, T. A., et al. (2020) · Nature · doi:10.1038/s41586-020-2702-1 · Cited by 366
Metadata
- Authors
- Fischer, M., Schnell, N., Chattaway, J., Davies, P., Dixon, G., & Sanders, D.
- Affiliations
- University of York (GB)
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1997-12-15
- Volume
- 419
- Issue
- 2-3
- Pages
- 259-262
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2155529170
- Cited by
- 185
- References
- 17
- Citations by year
- 2026: 7 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 4 · 2020: 4 · 2019: 5 · 2018: 5 · 2017: 11 · 2016: 10 · 2015: 6 · 2014: 2 · 2013: 11 · 2012: 12
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
- Life Sciences › Neuroscience › Sensory Systems › Ion Channels and Receptors
- Keywords
- Saccharomyces cerevisiae, calcium influx, mating, MID1, knockout mutants, pheromone sensitivity, calcium-dependent signaling
- MeSH terms
- Base Sequence, Calcium, Fungal Proteins, Genes, Fungal, Molecular Sequence Data, Saccharomyces cerevisiae, Calcium Channels, Ion Transport, Saccharomyces cerevisiae Proteins
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