Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

Dignam, J. D., Lebovitz, R. M., & Roeder, R. G. (1983) · Nucleic Acids Research · doi:10.1093/nar/11.5.1475 · Cited by 11,262

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

Mahley, R. W. (1988) · Science · doi:10.1126/science.3283935 · Cited by 4,028

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.

Hixson, J., & Vernier, D. (1990) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43176-1 · Cited by 2,933

Apolipoprotein E polymorphism and atherosclerosis.

Davignon, J., Gregg, R. E., & Sing, C. F. (1988) · Arteriosclerosis: An Official Journal of the American Heart Association, Inc. · doi:10.1161/01.atv.8.1.1 · Cited by 1,981

[31] Detection and localization of single base changes by denaturing gradient gel electrophoresis

Myers, R., Maniatis, T., & Lerman, L. S. (1987) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(87)55033-9 · Cited by 934

Apolipoprotein E: Structure-Function Relationships

Weisgraber, K. H. (1994) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(08)60642-7 · Cited by 830

Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

Das, H. K., McPherson, J. D., Bruns, G. A. P., Karathanasis, S. K., & Breslow, J. L. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)88963-3 · Cited by 354

Expression of the human apolipoprotein E gene is regulated by multiple positive and negative elements.

Smith, J. D., Melián, A., Leff, T., & Breslow, J. L. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68477-7 · Cited by 114

Polymorphism in the human apolipoprotein A-I gene promoter region. Association of the minor allele with decreased production rate in vivo and promoter activity in vitro.

Smith, J. D., Brinton, E. A., & Breslow, J. L. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115783 · Cited by 97

Complexité génétique de la maladie d’Alzheimer

Chartier‐Harlin, M., Goumidi, L., & Lambert, J. (2004) · Revue Neurologique · doi:10.1016/s0035-3787(04)70899-1 · Cited by 2

A prevalence study of single nucleotide polymorphisms in the promoter of the apolipoprotein E gene in different ethnic groups in Malaysia

Ganesan, D., & Wong, K. T. (2012) · Cited by 2

APOE −491 T allele may reduce the risk of atherosclerotic lesions among middle-aged women

Bañares, V. G., Bardach, A., Peterson, G., Tavella, M. J., & Schreier, L. E. (2011) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-011-1134-5 · Cited by 1

Apolipoprotein E promoter genotypes are not associated with white matter hyperintensity development in high-altitude careers

Chapleau, R. R., Martin, C. A., Hughes, S. R., Baldwin, J. C., Sladky, J. H., Sherman, P. M., & Grinkemeyer, M. D. (2019) · BMC Research Notes · doi:10.1186/s13104-019-4654-9 · Cited by 1

Nutritional Genomics: Concepts, Tools and Expectations

Daniel, H., & Wenzel, U. (2006) · Wiley eBooks · doi:10.1002/3527608109.ch1 · Cited by 1

Enfermedad de Alzheimer: deterioro cognitivo y funcional asociado a polimorfismos de APOE y A2M

Fariñas, M. T. F., Gregório, P. G., Sastre, I., & Bullido, M. J. (2002) · Revista Española de Geriatría y Gerontología · doi:10.1016/s0211-139x(02)74786-0 · Cited by 1

The Advantages of Haplotype Analysis of the Promoter Region of the Human Apolipoprotein E Gene

McLaughlin, D. P., Sharma, A. K., McGinley, A., & Samra, G. S. (2001) · Analytical Biochemistry · doi:10.1006/abio.2001.5425 · Cited by 1

ApoE Polymorphisms and Severity of Open-Angle Glaucoma

Pang, C. P., Tham, C. C. Y., & Lam, D. S. C. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-373-8_18 · Cited by 1

Regulierung und Verfügbarkeit von Apolipoprotein E in Astrozyten

Hamker, U. (2005) · edoc Publication server (Humboldt University of Berlin) · doi:10.18452/15272

Comentarios bibliográficos

Solà, R. (2006) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/s0214-9168(06)73662-2

Letter by Singh et al Regarding Article, “Apolipoprotein Isoform E4 Does Not Increase Coronary Heart Disease Risk in Carriers of Low-Density Lipoprotein Receptor Mutations”

Singh, P., Napoli, M. D., & Singh, M. (2012) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.111.962274

Genetic Variation and Individualized Medicine

Mansell, J. L., Tierney, R., Driban, J. B., Clegg, S. M., Higgins, M. J., Mishra, A. K., & Krynetskiy, E. Y. (2010) · Journal of Sport Rehabilitation · doi:10.1123/jsr.19.4.389

Association and functional studies on promoter polymorphisms within the apolipoprotein E gene, regarding lipid metabolism and atherosclerosis

Viiri, L. E. (2008) · Tampere University Institutional Repository (Tampere University)

Alzheimer´s disease and apolipoprotein E.A prospective, population-based molecular genetic and neuropathological study of individuals aged 85 years or more

Polvikoski, T. M. (2004) · Työväentutkimus Vuosikirja

Apolipoprotein E Gene and Alpha 1-Antichymotrypsin Gene in Brain of Sporadic Alzheimer's Disease

Kim, S.-H., Han, S.-Y., Choi, Y.-S., & Lee, K. (2002) · Journal of the Korean Neurological Association

Efeitos do treinamento aeróbio na cognição e no metabolismo cerebral em repouso em sujeitos com comprometimento cognitivo leve

Porto, F. H. D. G. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2017.tde-27102017-100935

Association of APOE − 219G > T and − 427T > C polymorphic variants in transcriptional regulatory region of APOE gene with gallbladder stone: A north Indian case-control study

Dwivedi, S., Madeshiya, A. K., Singh, S., Chandra, A., & Mahdi, A. A. (2018) · Meta Gene · doi:10.1016/j.mgene.2018.04.002

Aging, cognitive ability and the risk of dementia in the Helsinki Birth Cohort Study

Rantalainen, V. (2019) · Työväentutkimus Vuosikirja

Genetics of sport-related concussion

Fie, S. M., & September, A. V. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816193-7.00016-6

Gender and age specific contributions of additional DNA sequence variation in the 5′ regulatory region of the APOE gene to prediction of measures of lipid metabolism

Biochemistry, C. (2002) · Atherosclerosis Supplements · doi:10.1016/s1567-5688(02)80731-0

Secure similar patients query with homomorphically evaluated thresholds

Pratapa, M., & Essex, A. (2024) · Journal of Information Security and Applications · doi:10.1016/j.jisa.2024.103861

A case-control association study of APOE promoter region variants with glaucoma in North Indian population

Passan, S., Goyal, S., Bhat, M. A., Singh, R., Kaur, M., & Vanita, V. (2025) · Human Immunology · doi:10.1016/j.humimm.2025.111299

Towards mapping QTLs : influencing parameters of lipid metabolism in human twins

Beekman, M. (2004) · Data Archiving and Networked Services (DANS)

Untersuchungen zu den genetischen Ursachen der altersabhängigen Makuladegeneration (AMD)

Fritsche, L. G. (2009) · University of Regensburg Publication Server (University of Regensburg) · doi:10.5283/epub.12354

Therapeutic potential of honey in Alzheimer’s disease management

Sharma, S., Sharma, J., & Maharana, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-34147-2.00021-8

Facteurs métaboliques de risque cardio-vasculaire : interaction entre les régimes alimentaires et les polymorphismes de gènes impliqués dans le métabolisme des lipides

Hammoud, A. (2010) · theses.fr (ABES) · doi:10.70675/c282a641z49c3z45c9za640z109f3de2a616

Γενετική μελέτη συσχέτισης πολυμορφισμών σε γονίδια ιντερλευκινών σε ασθενείς με κρανιοεγκεφαλική κάκωση

Dardioti, M. (2010) · doi:10.12681/eadd/18595

Untitled work

Cole (2000) · doi:10.1002/1097-0029(20000815)50:4

Functional Characterization of Three Single-Nucleotide Polymorphisms Present in the Human APOε Promoter Sequence: Differential Effects in Neuronal Cells and on DNA–Protein Interactions

Maloney, B., Ge, Y., Petersen, R. C., Hardy, J., Rogers, R., Pérez‐Tur, J., & Lahiri, D. K. (2010) · UCL Discovery (University College London) · Cited by 2

A functional mutation at position -155 in porcine APOE promoter affects gene expression

Li, S., Zhang, H., Gao, P., Chen, Z., Wang, C., & Li, J. (2011) · BMC Genetics · doi:10.1186/1471-2156-12-40 · Cited by 8

Functional characterization of three single‐nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA–protein interactions

Maloney, B., Ge, Y., Petersen, R. C., Hardy, J., Rogers, J. T., Pérez‐Tur, J., & Lahiri, D. K. (2009) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30973 · Cited by 43

The Advantages of Haplotype Analysis of the Promoter Region of the Human Apolipoprotein E Gene

McLaughlin, D. P., Sharma, A. K., McGinley, A., & Samra, G. S. (2001) · Analytical Biochemistry · doi:10.1006/abio.2001.5425 · Cited by 1

Screening reveals conserved and nonconserved transcriptional regulatory elements including an E3/E4 allele-dependent APOE coding region enhancer

Chen, H. P., Lin, A., Bloom, J. S., Khan, A. H., Park, C. C., & Smith, D. (2008) · Genomics · doi:10.1016/j.ygeno.2008.07.009 · Cited by 18