Role of the Liver in the Degradation of Lipoproteins

The Metabolic Basis of Inherited Disease.

(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-503_7 · Cited by 7,807 · see citing works

PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASE

Miller, G. J., & Miller, N. E. (1975) · The Lancet · doi:10.1016/s0140-6736(75)92376-4 · Cited by 2,621 · see citing works

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

Goldstein, L. J., & Brown, S. M. (1977) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.46.070177.004341 · Cited by 2,455 · see citing works

The plasma lecithin:cholesterol acyltransferase reaction

Glomset, J. A. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43114-1 · Cited by 2,409 · see citing works

Coated pits, coated vesicles, and receptor-mediated endocytosis

Goldstein, J. L., Anderson, R. G. W., & Brown, M. S. (1979) · Nature · doi:10.1038/279679a0 · Cited by 2,073 · see citing works

Atherogenesis: a postprandial phenomenon.

Zilversmit, D. B. (1979) · Circulation · doi:10.1161/01.cir.60.3.473 · Cited by 1,701 · see citing works

Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms.

Weisgraber, K. H., Rall, S. C., & Mahley, R. W. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52510-8 · Cited by 777 · see citing works

Lipolytic Enzymes and Plasma Lipoprotein Metabolism

Nilsson‐Ehle, P., Garfinkel, A. S., & Schotz, M. C. (1980) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.49.070180.003315 · Cited by 754 · see citing works

Receptor-mediated endocytosis: insights from the lipoprotein receptor system.

Brown, M. S., & Goldstein, J. L. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.7.3330 · Cited by 711 · see citing works

Abnormal lipoprotein receptor‐binding activity of the human E apoprotein due to cysteine‐arginine interchange at a single site

Weisgraber, K. H., Innerarity, T. L., & Mahley, R. W. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34954-8 · Cited by 673 · see citing works

Protein-lipid relationships in human plasma

Barr, D. P., Russ, E. M., & Eder, H. A. (1951) · The American Journal of Medicine · doi:10.1016/0002-9343(51)90183-0 · Cited by 635 · see citing works

Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons.

Kane, J. P., Hardman, D. A., & Paulus, H. E. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.5.2465 · Cited by 584 · see citing works

Increased binding of low density lipoprotein to liver membranes from rats treated with 17 alpha-ethinyl estradiol.

Kovanen, P. T., Brown, M. S., & Goldstein, J. L. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86495-5 · Cited by 567 · see citing works

Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit) *1Incidence and development of atherosclerosis and xanthoma

Watanabe, Y. (1980) · Atherosclerosis · doi:10.1016/0021-9150(80)90234-8 · Cited by 547 · see citing works

Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver.

Hamilton, R. L., Williams, M. C., Fielding, C. J., & Havel, R. J. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108513 · Cited by 538 · see citing works

Formation of cholesteryl ester-rich particulate lipid during metabolism of chylomicrons

Redgrave, T. G. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106255 · Cited by 498 · see citing works

The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E.

Windler, E. E. T., Kovanen, P. T., Chao, Y. S., Brown, M. S., Havel, R. J., & Goldstein, J. L. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70487-6 · Cited by 456 · see citing works

Relative contributions by liver and intestine to individual plasma apolipoproteins in the rat.

Wu, A. L., & Windmueller, H. G. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50321-5 · Cited by 446 · see citing works

Lipoprotein structure and metabolism.

Jackson, R. L., Morrisett, J. D., & Gotto, A. M. (1976) · Physiological Reviews · doi:10.1152/physrev.1976.56.2.259 · Cited by 435 · see citing works

Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor. Identity with the chylomicron remnant transport process.

Sherrill, B. C., Innerarity, T. L., & Mahley, R. W. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85951-3 · Cited by 426 · see citing works

Lipoprotein apoprotein metabolism.

Schaefer, E. J., Eisenberg, S., & Levy, R. I. (1978) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41267-2 · Cited by 386 · see citing works

Lipoprotein binding to canine hepatic membranes. Metabolically distinct apo-E and apo-B,E receptors.

Hui, D. Y., Innerarity, T. L., & Mahley, R. W. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69254-9 · Cited by 383 · see citing works

Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.

Mahley, R. W., Hui, D. Y., Innerarity, T. L., & Weisgraber, K. H. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110365 · Cited by 375 · see citing works

Determinants of hepatic uptake of triglyceride-rich lipoproteins and their remnants in the rat.

Windler, E. E. T., Chao, Y. S., & Havel, R. J. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70811-4 · Cited by 365 · see citing works

Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat.

Shelburne, F. A., Hanks, J., Meyers, W., & Quarfordt, S. H. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109710 · Cited by 358 · see citing works

Protein-lipid relationships in human plasma

Russ, E. M., Eder, H. A., & Barr, D. P. (1951) · The American Journal of Medicine · doi:10.1016/0002-9343(51)90182-9 · Cited by 351 · see citing works

Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase

Breckenridge, W. C., Little, J., Alaupovic, P., Wang, C. C., Kuksis, A., Kakis, G., Lindgren, F. T., & Gardiner, G. W. (1982) · Atherosclerosis · doi:10.1016/0021-9150(82)90136-8 · Cited by 325 · see citing works

Characterization of remnants produced during the metabolism of triglyceride-rich lipoproteins of blood plasma and intestinal lymph in the rat.

Mjøs, O. D., Færgeman, O., Hamilton, R. L., & Havel, R. J. (1975) · Journal of Clinical Investigation · doi:10.1172/jci108130 · Cited by 322 · see citing works

Hepatic catabolism of rat and human lipoproteins in rats treated with 17 alpha-ethinyl estradiol.

Chao, Y. S., Windler, E. E. T., Chen, G. C., & Havel, R. J. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86494-3 · Cited by 317 · see citing works

Altered Metabolism (In Vivo and In Vitro) of Plasma Lipoproteins after Selective Chemical Modification of Lysine Residues of the Apoproteins

Mahley, R. W., Innerarity, T. L., Weisgraber, K. H., & Oh, S. Y. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109518 · Cited by 316 · see citing works

Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.

Schneider, W. J., Kovanen, P. T., Brown, M. S., Goldstein, J. L., Utermann, G., Weber, W., Havel, R. J., Kotite, L., Kane, J. P., Innerarity, T. L., et al. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110330 · Cited by 310 · see citing works

Conversion of very low density lipoprotein to low density lipoprotein. A metabolic study of apolipoprotein B kinetics in human subjects.

Sigurdsson, G. T., Nicoll, A. D., & Lewis, B. (1975) · Journal of Clinical Investigation · doi:10.1172/jci108229 · Cited by 308 · see citing works

Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts.

Innerarity, T. L., Pitas, R. E., & Mahley, R. W. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50713-4 · Cited by 300 · see citing works

Preferential Utilization of Free Cholesterol From High-Density Lipoproteins for Biliary Cholesterol Secretion in Man

Schwartz, C. C., Halloran, P. F., Vlahčevič, Z. R., Gregory, D. H., & Swell, L. (1978) · Science · doi:10.1126/science.204996 · Cited by 300 · see citing works

Rat Intestine Secretes Discoid High Density Lipoprotein

Green, P. H. R., Tall, A. R., & Glickman, R. M. (1978) · Journal of Clinical Investigation · doi:10.1172/jci108963 · Cited by 269 · see citing works

Expression of the Familial Hypercholesterolemia Gene in Heterozygotes: Mechanism for a Dominant Disorder in Man

Brown, M. S., & Goldstein, J. L. (1974) · Science · doi:10.1126/science.185.4145.61 · Cited by 261 · see citing works

Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor.

Kita, T., Goldstein, J. L., Brown, M. S., Watanabe, Y., Hornick, C. A., & Havel, R. J. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.11.3623 · Cited by 259 · see citing works

Human Intestinal Lipoproteins

Green, P. H. R., Glickman, R. M., Saudek, C. D., Blum, C. B., & Tall, A. R. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109444 · Cited by 250 · see citing works

Metabolsim of apoB and apoC lipoproteins in man: kinetic studies in normal and hyperlipoproteininemic subjects

Berman, M. D., Hall, M., Levy, R. I., Eisenberg, S., Bilheimer, D. W., Phair, R. D., & Goebel, R. H. (1978) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41575-5 · Cited by 243 · see citing works

THE METABOLISM OF CHYLOMICRON CHOLESTEROL ESTER IN THE RAT

Goodman, D. S. (1962) · Journal of Clinical Investigation · doi:10.1172/jci104645 · Cited by 243 · see citing works

Tissue sites of degradation of apoprotein A-I in the rat.

Glass, C. K., Pittman, R. C., Keller, G. A., & Steinberg, D. H. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32346-9 · Cited by 241 · see citing works

Quantitation of the Transfer of Surface Phospholipid of Chylomicrons to the High Density Lipoprotein Fraction during the Catabolism of Chylomicrons in the Rat

Redgrave, T. G., & SMALL, D. M. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109435 · Cited by 237 · see citing works

Regulation of Cholesterol Biosynthesis in Normal and Malignant Tissues

(1970) · Current topics in cellular regulation · doi:10.1016/b978-0-12-152802-7.50009-8 · Cited by 227 · see citing works

Metabolic Fate of Chylomicron Phospholipids and Apoproteins in the Rat

Tall, A. R., Green, P. H. R., Glickman, R. M., & Riley, J. W. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109564 · Cited by 217 · see citing works

Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits.

Kita, T., Brown, M. S., Bilheimer, D. W., & Goldstein, J. L. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.18.5693 · Cited by 208 · see citing works

Purification from human plasma of a heparin-released lipase with activity against triglyceride and phospholipids.

Ehnholm, C., Shaw, W., Greten, H., & Brown, W. V. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40996-4 · Cited by 205 · see citing works

Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits.

Pittman, R. C., Carew, T. E., Attie, A., Witztum, J. L., Watanabe, Y., & Steinberg, D. H. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34287-x · Cited by 199 · see citing works

Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver.

Sherrill, B. C., & Dietschy, J. M. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)62331-8 · Cited by 197 · see citing works

Evidence for a lipoprotein carrier in human plasma catalyzing sterol efflux from cultured fibroblasts and its relationship to lecithin:cholesterol acyltransferase.

Fielding, C. J., & Fielding, P. E. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.6.3911 · Cited by 196 · see citing works

CHOLESTEROL METABOLISM

Gould, R. G., TAYLOR, C. B., Hagerman, J. S., Warner, I., & Campbell, D. J. (1953) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66206-4 · Cited by 189 · see citing works

Specific high-affinity binding of high density lipoproteins to cultured human skin fibroblasts and arterial smooth muscle cells.

Biesbroeck, R., Oram, J. F., Albers, J. J., & Bierman, E. L. (1983) · Journal of Clinical Investigation · doi:10.1172/jci110797 · Cited by 183 · see citing works

Receptor-mediated low density lipoprotein catabolism in man.

Shepherd, J., Bicker, S., Lorimer, A. R., & Packard, C. J. (1979) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40002-1 · Cited by 182 · see citing works

The mechanism of assimilation of constituents of chylomicrons, very low density lipoproteins and remnants - a new theory

Felts, J. M., Itakura, H., & Crane, R. (1975) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(75)90524-0 · Cited by 176 · see citing works

Quantitative studies of the metabolism of chylomicron triglycerides and cholesterol by liver and extrahepatic tissues of sheep and dogs

Bergman, E. N., Havel, R. J., Wolfe, B. M. J., & Bøhmer, T. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106674 · Cited by 175 · see citing works

Apolipoprotein B variant derived from rat intestine.

Krishnaiah, K. V., Walker, L., Borensztajn, J., Schonfeld, G., & Getz, G. S. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.7.3806 · Cited by 169 · see citing works

Structural and metabolic heterogeneity of beta-very low density lipoproteins from cholesterol-fed dogs and from humans with type III hyperlipoproteinemia.

Fainaru, M., Mahley, R. W., Hamilton, R. L., & Innerarity, T. L. (1982) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38102-5 · Cited by 156 · see citing works

The Synthesis of Plasma Lipoprotein by Rat Liver

Marsh, J. B., & Whereat, A. F. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69648-6 · Cited by 151 · see citing works

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l.

Bell, J. J., Sargeant, T., & Watson, J. A. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33712-2 · Cited by 148 · see citing works

Apolipoprotein B is structurally and metabolically heterogeneous in the rat.

Elovson, J., Huang, Y. O., Baker, N., & Kannan, R. R. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.1.157 · Cited by 147 · see citing works

Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma.

Fielding, P. E., Fielding, C. J., Havel, R. J., Kane, J. P., & Tun, P. (1983) · Journal of Clinical Investigation · doi:10.1172/jci110789 · Cited by 147 · see citing works

Effects of cholestyramine on receptor-mediated plasma clearance and tissue uptake of human low density lipoproteins in the rabbit.

Slater, H. R., Packard, C. J., Bicker, S., & Shepherd, J. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70450-5 · Cited by 144 · see citing works

Metabolism of apoprotein B of plasma very low density lipoproteins in the rat.

Færgeman, O., Sata, T., Kane, J. P., & Havel, R. J. (1975) · Journal of Clinical Investigation · doi:10.1172/jci108220 · Cited by 144 · see citing works

Adrenal cholesterol uptake from plasma lipoproteins: regulation by corticotropin.

Gwynne, J. T., MAHAFFEE, D. D., Brewer, H. B., & Ney, R. L. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.12.4329 · Cited by 144 · see citing works

The effect of human C apolipoproteins on the in vitro hepatic metabolism of triglyceride emulsions in the rat.

Quarfordt, S. H., Michalopoulos, G. K., & Schirmer, B. D. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33329-5 · Cited by 132 · see citing works

Tissue sites of degradation of low density lipoprotein: Application of a method for determining the fate of plasma proteins

Pittman, R. C., Attie, A., Carew, T. E., & Steinberg, D. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.10.5345 · Cited by 132 · see citing works

A biochemical and morphologic study of very low density lipoproteins in carbohydrate-induced hypertriglyceridemia

Ruderman, N. B., Jones, A. L., Krauss, R. M., & Shafrir, E. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106615 · Cited by 130 · see citing works

Regulation of human plasma lecithin:cholesterol acyltransferase activity by lipoprotein acceptor cholesteryl ester content.

Fielding, C. J., & Fielding, P. E. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69742-5 · Cited by 124 · see citing works

Variant forms of plasma apolipoprotein B. Hepatic and intestinal biosynthesis and heterogeneous metabolism in the rat.

Wu, A. L., & Windmueller, H. G. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69493-7 · Cited by 119 · see citing works

Metabolic heterogeneity of apolipoprotein B in the rat

Sparks, C. E., & Marsh, J. B. (1981) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34967-1 · Cited by 119 · see citing works

Autoradiographic localization of the sites of uptake, cellular transport, and catabolism of low density lipoproteins in the liver of normal and estrogen-treated rats

Chao, Y., Jones, A. L., Hradek, G. T., Windler, E. E. T., & Havel, R. J. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.1.597 · Cited by 119 · see citing works

THE METABOLISM OF CHYLOMICRON CHOLESTERYL ESTER IN RAT LIVER

Stein, O., Stein, Y., Goodman, D. S., & Fidge, N. (1969) · The Journal of Cell Biology · doi:10.1083/jcb.43.3.410 · Cited by 116 · see citing works

Paradoxical Increase in Rate of Catabolism of Low-Density Lipoproteins after Hepatectomy

Sniderman, A. D., Carew, T. E., Chandler, J. G., & Steinberg, D. H. (1974) · Science · doi:10.1126/science.183.4124.526 · Cited by 101 · see citing works

High-affinity uptake and degradation of ApoE-free high-density lipoprotein and low-density lipoprotein in cultured porcine hepatocytes

Bachorik, P. S., Franklin, F. A., Virgil, D. G., & Kwiterovich, P. O. (1982) · Biochemistry · doi:10.1021/bi00265a044 · Cited by 101 · see citing works

Lipoproteins in a nonrecirculating perfusate of rat liver

Marsh, J. B. (1974) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36754-7 · Cited by 101 · see citing works

The Metabolic Basis of Inherited Disease

Garland, J. T. (1983) · JAMA · doi:10.1001/jama.1983.03330470071039 · Cited by 98 · see citing works

Rates of removal and degradation of chylomicron remnants by isolated perfused rat liver.

Cooper, A. D., & Yu, P. Y. (1978) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41296-9 · Cited by 96 · see citing works

Receptor-mediated catabolism of homologous low density lipoproteins in cultured pig hepatocytes.

Pangburn, S., Newton, R. S., Chang, C. M., Weinstein, D. B., & Steinberg, D. H. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69612-2 · Cited by 95 · see citing works

High affinity binding of chylomicron remnants to rat liver plasma membranes.

Carrella, M., & Cooper, A. D. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.338 · Cited by 91 · see citing works

Quantification of the hepatic contribution to the catabolism of high density lipoproteins in rats.

Sigurdsson, G. T., Noël, S. P., & Havel, R. J. (1979) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40614-5 · Cited by 91 · see citing works

The metabolism of chylomicron remnants by isolated perfused rat liver

Cooper, A. D. (1977) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(77)90204-1 · Cited by 90 · see citing works

Hepatic Catabolism of Low Density Lipoprotein: Mechanisms and Metabolic Consequences

Attie, A., Pittman, R. C., & Steinberg, D. H. (1982) · Hepatology · doi:10.1002/hep.1840020215 · Cited by 76 · see citing works

Characterization of chylomicron remnant binding to rat liver membranes.

Cooper, A. D., Erickson, S. K., Nutik, R., & Shrewsbury, M. A. (1982) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38172-4 · Cited by 76 · see citing works

Studies on the etiology of the hyperlipemia in rats fed an atherogenic diet

Kris‐Etherton, P. M., & Cooper, A. D. (1980) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39793-5 · Cited by 75 · see citing works

Hepatic binding and internalization of low density lipoprotein-gold conjugates in rats treated with 17 alpha-ethinylestradiol.

Handley, D. A., ARBEENY, C. M., Eder, H., & Chien, S. (1981) · The Journal of Cell Biology · doi:10.1083/jcb.90.3.778 · Cited by 69 · see citing works

Unaltered catabolism of desialylated low-density lipoprotein in the pig and in cultured rat hepatocytes

Attie, A., Weinstein, D. B., Freeze, H. H., Pittman, R. C., & Steinberg, D. H. (1979) · Biochemical Journal · doi:10.1042/bj1800647 · Cited by 68 · see citing works

An in vitro model for the catabolism of rat chylomicrons

Noël, S. P., Dolphin, P. J., & Rubinstein, D. (1975) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(75)80449-9 · Cited by 66 · see citing works

The synthesis of low- and high-density lipoproteins by rat liver in vitro

Radding, C. M., Bragdon, J. H., & Steinberg, D. H. (1958) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(58)90082-9 · Cited by 63 · see citing works

Role of exogenous cholesterol in regulation of adrenal steroidogenesis in the rat.

Verschoor-Klootwyk, A. H., Verschoor, L., Azhar, S., & Reaven, G. M. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34432-6 · Cited by 59 · see citing works

Regulation of sterol synthesis in adrenal gland of the rat by both high and low density human plasma lipoproteins

Andersen, J. M., & Dietschy, J. M. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(76)80214-8 · Cited by 56 · see citing works

High levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in the ovary of the pregnant rabbit.

Kovanen, P. T., Goldstein, J. L., & Brown, M. S. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34666-5 · Cited by 53 · see citing works

Apolipoprotein E

Zannis, V. I., & Breslow, J. L. (1982) · Molecular and Cellular Biochemistry · doi:10.1007/bf00223534 · Cited by 52 · see citing works

Uptake and degradation of human chylomicrons by macrophages in culture. Role of lipoprotein lipase.

Östlund‐Lindqvist, A., Gustafson, S., Lindqvist, P., Witztum, J. L., & Little, J. A. (1983) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.3.5.433 · Cited by 49 · see citing works

Distributio of chylomicron cholesteryl ester between parenchymal and Kupffer cells of rat liver

Nilsson, Å., & Zilversmit, D. B. (1971) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(71)90085-3 · Cited by 47 · see citing works

Cholesterol biosynthesis in transplantable hepatomas: evidence for impairment of uptake and storage of dietary cholesterol

Harry, D. S., Morris, H. P., & McIntyre, N. R. (1971) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39511-0 · Cited by 47 · see citing works

Lipoprotein metabolism by rat hepatomas. Studies on the etiology of defective dietary feedback inhibition of cholesterol synthesis.

Barnard, G. F., Erickson, S. K., & Cooper, A. D. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111399 · Cited by 43 · see citing works

Low density lipoprotein receptors and catabolism in primary cultures of rabbit hepatocytes

Soltys, P. A., & Portman, O. W. (1979) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(79)90247-9 · Cited by 43 · see citing works

Role of parenchymal and non-parenchymal rat liver cells in the uptake of cholesterolester-labeled serum lipoproteins

van Berkel, T. J. C., & van Tol, A. (1979) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(79)92120-x · Cited by 34 · see citing works

Effect of removal of lipoproteins of different composition on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and hepatic very low density lipoprotein secretion

Zuiden, P. E. V., Erickson, S. K., & Cooper, A. D. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37982-7 · Cited by 33 · see citing works

Effect of chloroquine on low-density lipoprotein catabolic pathway in rat hepatocytes

Hornick, C. A., Jones, A. L., Renaud, G., Hradek, G. T., & Havel, R. J. (1984) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1984.246.2.g187 · Cited by 31 · see citing works

Comparison of binding and removal of remnants of triglyceride-rich lipoproteins of intestinal and hepatic origin by rat liver in vitro

Cooper, A. D., Shrewsbury, M. A., & Erickson, S. K. (1982) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1982.243.5.g389 · Cited by 27 · see citing works

Hepatic uptake of phospholipid-depleted chylomicrons in vivo. Comparison with the uptake of chylomicron remnants

Borensztajn, J., & Kotlar, T. J. (1981) · Biochemical Journal · doi:10.1042/bj2000547 · Cited by 26 · see citing works

Monoacylglycerol accumulation in low and high density lipoproteins during the hydrolysis of very low density lipoprotein triacylglycerol by lipoprotein lipase

El-Maghrabi, R. A., Waite, M., & Rudel, L. L. (1978) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(78)91633-9 · Cited by 26 · see citing works

The apoprotein B-independent hepatic uptake of chylomicron remnants

Borensztajn, J., Getz, G. S., Padley, R. J., & Kotlar, T. J. (1982) · Biochemical Journal · doi:10.1042/bj2040609 · Cited by 25 · see citing works

Stimulation of lipoprotein receptors and role of lipoprotein and cellular cholesterol during gonadotropin-induced desensitization of steroidogenic response in luteinized rat ovary.

Azhar, S., Chen, Y. D., & Reaven, G. M. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32726-1 · Cited by 23 · see citing works

The uptake and metabolism of chylomicron-remnant lipids by nonparenchymal cells in perfused liver and by Kupffer cells in culture.

Lippiello, P. M., Dijkstra, J., Galen, M. J. M. V., Scherphof, G. L., & Waite, B. M. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)68984-2 · Cited by 22 · see citing works

Effects of Chloroquine and Colchicine on the Degradation of Chyle Cholesteryl Ester and Phospholipids in vivo

Florén, C., Nordgren, H., & Nilsson, Å. (1977) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1977.tb11887.x · Cited by 16 · see citing works

Effect of apolipoproteins on the induction of hepatic steatosis in rats

Quarfordt, S. H., Shelburne, F. A., Meyers, W., Jakoi, L., & Hanks, J. (1981) · Gastroenterology · doi:10.1016/0016-5085(81)90205-5 · Cited by 15 · see citing works

Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease

Petersen, K. F., Dufour, S., Hariri, A., Nelson-Williams, C., Foo, J. N., Zhang, X.-M., Dziura, J., Lifton, R. P., & Shulman, G. I. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0907295 · Cited by 428 · see citing works

Scavenger functions of the liver endothelial cell

Smedsrød, B. H., Pertoft, H., Gustafson, S., & Laurent, T. C. (1990) · Biochemical Journal · doi:10.1042/bj2660313 · Cited by 328 · see citing works

Dietary Iron Overload and Induced Lipid Peroxidation Are Associated With Impaired Plasma Lipid Transport and Hepatic Sterol Metabolism in Rats

Brunet, S., Thibault, L., DELVIN, E. E., Yotov, W. V., Bendayan, M., & Levy, E. H. (1999) · Hepatology · doi:10.1002/hep.510290612 · Cited by 87 · see citing works

5 Dyslipoproteinaemia of liver disease

Miller, J. P. (1990) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(05)80080-1 · Cited by 86 · see citing works

Regulation of cholesterol metabolism in the intestine

Field, F. J., Kam, N. T. P., & Mathur, S. N. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)91040-d · Cited by 77 · see citing works

Characterization of the estrogen-induced lipoprotein receptor of rat liver.

Cooper, A. D., Nutik, R., & Chen, J. (1986) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38733-2 · Cited by 76 · see citing works

Effects of dietary soybean lecithin on plasma lipid transport and hepatic cholesterol metabolism in rats

Leblanc, M.-J., Brunet, S., Bouchard, G., Lamireau, T., Yousef, I. M., Gavino, V. C., Levy, E. H., & Tuchweber, B. (2003) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00253-x · Cited by 59 · see citing works

Characterization of chylomicron remnant clearance by retinyl palmitate label in normal humans.

Berr, F. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41517-2 · Cited by 56 · see citing works

Gene polymorphisms associated with non-alcoholic fatty liver disease and coronary artery disease: a concise review

Li, X., Sui, J.-Q., Lu, L., Zhang, N., Xu, X. Y., Dong, Q., Xin, Y., & Xuan, S. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0221-8 · Cited by 52 · see citing works

The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases

Chew, N., Chong, B., Ng, C. H., Kong, G., Chin, Y. H., Xiao, W., Lee, C. J. M., Dan, Y. Y., Muthiah, M. D., & Foo, R. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.971484 · Cited by 49 · see citing works

Biliary lipid secretion in patients with heterozygous familial hypercholesterolemia and combined hyperlipidemia. Influence of bezafibrate and fenofibrate.

Leiß, O., Meyer-Krahmer, K., & von Bergmann, K. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38795-2 · Cited by 48 · see citing works

Metabolism of high density lipoproteins by the perfused rabbit liver.

Mackinnon, M., Savage, J., Wishart, R., & Barter, P. J. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)35822-2 · Cited by 47 · see citing works

Regulation of bile acid synthesis in cultured rat hepatocytes: stimulation by apoE-rich high density lipoproteins.

Mackinnon, A. M., Drevon, C. A., Sand, T. M., & Davis, R. A. (1987) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38652-1 · Cited by 45 · see citing works

Modulation of endoplasmic reticulum-bound cholesterol regulatory enzymes by iron/ascorbate-mediated lipid peroxidation

Brunet, S., Thibault, L., Lepage, G., Seidman, E. G., Dubé, N., & Levy, E. H. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00197-5 · Cited by 41 · see citing works

Abnormal hepatobiliary and circulating lipid metabolism in the Long-Evans Cinnamon rat model of Wilson's disease

Levy, E. H., Brunet, S., Álvarez, F., Seidman, E. G., Bouchard, G., Escobar, E., & Martin, S. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.01.017 · Cited by 40 · see citing works

Risk factor compositions of nonalcoholic fatty liver disease change with body mass index in males and females

Wang, L., Guo, J., & Lu, J. (2016) · Oncotarget · doi:10.18632/oncotarget.9691 · Cited by 38 · see citing works

Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids

Kuipers, F., Spanjer, H. H., Havinga, R., Scherphof, G. L., & Vonk, R. J. (1986) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(86)90044-5 · Cited by 38 · see citing works

Circulating lipoproteins and hepatic sterol metabolism in Psammomys obesus prone to obesity, hyperglycemia and hyperinsulinemia

Zoltowska, M. (2001) · Atherosclerosis · doi:10.1016/s0021-9150(00)00711-5 · Cited by 34 · see citing works

Apolipoprotein C3(-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population

Li, M.-R. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i38.14010 · Cited by 35 · see citing works

Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells

Ellsworth, J. L., Chandrasekaran, C., & Cooper, A. D. (1991) · Biochemical Journal · doi:10.1042/bj2790175 · Cited by 25 · see citing works

Pathology of alcoholic liver disease

Harrison, D. J., & Burt, A. D. (1993) · Baillière s Clinical Gastroenterology · doi:10.1016/0950-3528(93)90006-e · Cited by 18 · see citing works

Stimulation of LDL receptor activity in Hep‐G2 cells by a serum factor(s)

Ellsworth, J. L., Brown, C. L., & Cooper, A. D. (1988) · Journal of Cellular Physiology · doi:10.1002/jcp.1041350208 · Cited by 18 · see citing works

Chapter 10 Lecithin cholesterol acyltransferase

Jonas, A. (1987) · New comprehensive biochemistry · doi:10.1016/s0167-7306(08)60204-5 · Cited by 17 · see citing works

Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events

Saki, S., Saki, N., Poustchi, H., & Malekzadeh, R. (2020) · Middle East Journal of Digestive Diseases · doi:10.34172/mejdd.2020.166 · Cited by 14 · see citing works

A comparative study of the rate-limiting enzymes of cholesterol synthesis, esterification and catabolism in the alloxan-induced diabetic rat and rabbit

Devery, R., O’Meara, N., Collins, P. B., Johnson, A. H., Scott, L. C., & Tomkin, G. H. (1987) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(87)90342-7 · Cited by 14 · see citing works

Biodynamique des lipides: nouvelles perspectives

Hauton, J. C. (1987) · Biochimie · doi:10.1016/0300-9084(87)90043-5 · Cited by 13 · see citing works

Quantitative studies on fatty acid metabolism in isolated parenchymal cells from normal and cirrhotic livers in rats

Zimmermann, T., Franke, H., Peuker, M., & Dargel, R. (1992) · Journal of Hepatology · doi:10.1016/0168-8278(92)90005-a · Cited by 12 · see citing works

Bile duct cells: a novel in vitro model for the study of lipid metabolism and bile acid production

Zoltowska, M., DELVIN, E. E., Paradis, K., Seidman, E. G., & Levy, E. H. (1999) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1999.276.2.g407 · Cited by 11 · see citing works

Hepatic Chylomicron Remnant (Apolipoprotein E) Receptors: Their Physiologic and Clinical Importance

Florén, C., & Nilsson, Å. (1987) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365528708991890 · Cited by 11 · see citing works

Circulating high density lipoprotein distinguishes alcoholic hepatitis from heavy drinkers and predicts 90-day outcome

Mathur, K., Vilar‐Gómez, E., Connelly, M. A., He, H., Sanyal, A. J., Chalasani, N., & Jiang, Z. G. (2021) · Journal of clinical lipidology · doi:10.1016/j.jacl.2021.10.002 · Cited by 10 · see citing works

Celiac Disease and Non-Celiac Gluten Sensitivity

Rodrigo, L. (2017) · InTech eBooks · doi:10.5772/65184 · Cited by 9 · see citing works

A comparative study of the rate-limiting enzymes of cholesterol synthesis, esterification and catabolism in the rat and rabbit

Devery, R., O’Meara, N., Collins, P., Johnson, A. H., Scott, L. C., & Tomkin, G. H. (1987) · Comparative Biochemistry and Physiology Part B Comparative Biochemistry · doi:10.1016/0305-0491(87)90376-2 · Cited by 8 · see citing works

Apolipoprotein E in hepatocellular liver disease

Florén, C. (1988) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365518809085413 · Cited by 8 · see citing works

Removal rates of rat serum [3H] labeled very low density lipoproteins after consumption of two different low protein diets

Bouchenak, M., Belleville, J., Boquillon, M., Scherrer, B., & Prost, J. (1991) · Nutrition Research · doi:10.1016/s0271-5317(05)80349-5 · Cited by 8 · see citing works

The effect of perfluorochemical artificial blood on lipoprotein metabolism in rats

Nagata, Y., Mondon, C. E., & Cooper, A. D. (1990) · Metabolism · doi:10.1016/0026-0495(90)90101-h · Cited by 5 · see citing works

Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats

Kojić-Damjanov, S., Djerić, M., Mikov, M., Kuhajda, K., & Kevrešan, S. (2008) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/bf03191024 · Cited by 3 · see citing works

Celiac Disease and Non-celiac Gluten Sensitivity

Cartee, A. K., & Murray, J. A. (2019) · Springer eBooks · doi:10.1007/978-3-030-01117-8_17 · Cited by 2 · see citing works

Lipid- und Lipoproteinstoffwechsel

Stein, J. H., & Böhles, H. J. (2003) · Springer eBooks · doi:10.1007/978-3-642-55896-2_10 · Cited by 2 · see citing works

Chylomicron metabolism in experimental cirrhosis and cholestasis

Damião, A. O. M. C., Sipahi, A. M., Albuquerque, M., Laudanna, A. A., & Quintão, E. C. R. (1993) · Research in Experimental Medicine · doi:10.1007/bf02576215 · Cited by 2 · see citing works

Receptor-mediated uptake of homologous low-density lipoproteins by isolated liver parenchymal cells of fetal rats

D�rer, U., Sommer, M., Franke, H., Schlag, B., & Dargel, R. (1988) · Cell and Tissue Research · doi:10.1007/bf00220035 · Cited by 2 · see citing works

Metabolism in vivo of [14C]oleic acid and [3H]retinol of lipid-poor and lipid-rich chyle

Tso, P., & Nilsson, Å. (1992) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(92)90293-5 · Cited by 1 · see citing works

The effect of felodipine on the uptake and degradation of acetylated LDL in mouse peritoneal cells and on the distribution of acetylated LDL in macrophage-rich organs of the rat

Gustafson, S., Menschik-Lundin, A., Nordlander, M., & Östlund‐Lindqvist, A. (1993) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(93)90088-i · Cited by 1 · see citing works

Leber

Löffler, G., & Weiß, L. (1988) · Springer-Lehrbuch · doi:10.1007/978-3-642-87858-9_29

Leber

Löffler, G., & Weiß, L. (1988) · Springer-Lehrbuch · doi:10.1007/978-3-662-09348-1_29

Protein and cell therapy for lecithin-cholesterol acyltransferase (LCAT) deficiency

Low, J. K. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)

Introduction to Lipids and Lipoproteins

Feingold, K. R., & Grünfeld, C. (2015) · MDText.com, Inc. eBooks · Cited by 306 · see citing works

Lipoprotein Metabolism

Greten, H. (1976) · Springer eBooks · doi:10.1007/978-3-642-66323-9 · Cited by 164 · see citing works

Lipoprotein Physiology and Its Relationship to Atherogenesis

Ginsberg, H. N. (1990) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30322-0 · Cited by 62 · see citing works

Mecanismos básicos: estructura, función y metabolismo de las lipoproteínas plasm

Errico, T. L., Chen, X., Martín-Campos, J. M., Julve, J., Escolá‐Gil, J. C., & Blanco‐Vaca, F. (2013) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2013.05.003 · Cited by 9 · see citing works

Genetic Mutations Affecting Human Lipoprotein Metabolism

(1985) · doi:10.1007/978-1-4615-9400-0_3 · Cited by 65 · see citing works