The DOI matches its Crossref record; 84 of the 85 references it cites were found in a registry or an index.
Is rectal pain sensitivity a biological marker for irritable bowel syndrome: psychological influences on pain perception.
Open accessAbstract
Background & aims Rectal pain sensitivity has been called a biological marker for irritable bowel syndrome, but this conclusion may be premature. This article is a critical review of the evidence for psychological influences on perception.Methods The world literature accessible through Index Medicus from 1973 to 1997 was systematically reviewed.Results Evidence favoring a biological basis for pain sensitivity is that two thirds of patients report pain at abnormally low thresholds of rectal distention despite normal somatic pain thresholds. Pain thresholds are not correlated with anxiety or depression. Evidence favoring psychological influences on perception is that patients with the irritable bowel syndrome rate even sham distentions as more painful, and when perception tests that minimize psychological influences are used, they have normal sensory thresholds. Also, stress alters sensory thresholds. Sensitization by repeated distention has been cited as evidence of a biological basis for hyperalgesia, but it is not unique to patients with irritable bowel. Brain imaging shows that different regions are activated by painful distention in patients with irritable bowel syndrome, but this is consistent with psychological influences on perception.Conclusions Psychological factors influence pain thresholds in patients with the irritable bowel syndrome. Two cognitive traits, selective attention to gastrointestinal sensations and disease attribution, may account for increased pain sensitivity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Recent investigations have found that mindfulness meditation induces changes in the activation of neural circuits implicated in interoception (awareness of stimuli originating inside the body (21)) and emotion regulation (22,23), while improving attentional control (24–27).”
From Mindfulness training reduces the severity of irritable bowel syndrome in women: Results of a randomized controlled trial (2011) · cites this paper as [25]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(1966) · Medical Entomology and Zoology · Cited by 10,293
Signal detection theory and psychophysics
Ingleby, D. (1967) · Journal of Sound and Vibration · doi:10.1016/0022-460x(67)90197-6 · Cited by 8,616
Functional bowel disorders and functional abdominal pain
Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A. (1999) · Gut · doi:10.1136/gut.45.2008.ii43 · Cited by 2,440
Towards positive diagnosis of the irritable bowel.
Manning, A. P., Thompson, W., Heaton, K. W., & Morris, A. F. (1978) · BMJ · doi:10.1136/bmj.2.6138.653 · Cited by 1,404
Altered rectal perception is a biological marker of patients with irritable bowel syndrome
Mertz, H., Naliboff, B. D., Munakata, J., Niazi, N., & Mayer, E. A. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90267-8 · Cited by 976
Basic and clinical aspects of visceral hyperalgesia
Mayer, E. A., & Gebhart, G. F. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90086-8 · Cited by 920
A Primer of Signal Detection Theory
McNicol, D. (2005) · Psychology Press eBooks · doi:10.4324/9781410611949 · Cited by 856
Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome
Ritchie, J. (1973) · Gut · doi:10.1136/gut.14.2.125 · Cited by 832
A Primer of Signal Detection Theory.
Hawkes, A. G., & McNicol, D. (1973) · Journal of the Royal Statistical Society Series A (General) · doi:10.2307/2345017 · Cited by 654
Tolerance for Rectosigmoid Distention in Irritable Bowel Syndrome
Whitehead, W. E., Holtkötter, B., Enck, P., Hoelzl, R., Holmes, K. D., Anthony, J. C., Shabsin, H. S., & Schuster, M. M. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90332-u · Cited by 592
Self-citation
Research works printed but not linked: 6
- Metivier S, Delvaux D, Louvel D, Lagier E, Fioramonti J, Bueno L, Frexinos J. Influence of stress on sensory thresholds to rectal distension in healthy volunteers (abstr). Gastroenterology 1996; 110:A717.
- Palsson OS, McCommons JJ, Burnett CK, Bradley LA, Whitehead WE. Relationship between bowel sensations: pain, urge to defecate and rectal fullness in iritable bowel syndrome (IBS) patients and healthy subjects (abstr). Gastroenterology 1995;108: A663.
- Bradley L, Richter J, Scarinci IC, Haile JE, Schan CA. Mechanisms of altered pain perception in non-cardiac chest pain patients (abstr). Gastroenterology 1993;104:A482.
- Mertz H, Fass R, Hirsh T, Yan-Go F, Mayer EA. Amitryptiline for functional dyspepsia: effect on symptoms, gastic sensitivity and sleep (abstr). Gastroenterology 1995;108:A649.
- Bell AM, Pemberton JH, Camilleri M, Hanson RB, Zinsmeister AR. The effect of acute stress on rectal tone and anal sphincter pressure (abstr). Gastroenterology 1989;96:A38.
- Crowell M, Musial F, Kollmannsperger P, Mueller J, Orr WC. Association of rectal tone during stress with sensitivity to disten- sion in the irritable bowel syndrome (abstr). Am J Gastroenterol 1993;88:1572.
Cited by
Sorted by citations
Items 201–300 of 314
No Brain, No Gain: The Role of Cognitive Processes in Irritable Bowel Syndrome
Lackner, J. M. (2005) · Journal of Cognitive Psychotherapy · doi:10.1891/jcop.19.2.125.66788 · Cited by 17
Schröder, L., Regnath, F., Glasauer, S., Hackenberg, A. E. C., Hente, J. M., Weilenmann, S., Pohl, D., von Känel, R., & Lehnen, N. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1029126 · Cited by 23
“stimulus strength is continuously increased (e.g., Ritchie, 1973; Mertz et al., 1995; Whitehead and Palsson, 1998; Verne et al., 2001; Bouin et al., 2002; Azpiroz et al., 2007; Barbara et al., 2011).”
BackgroundLackner, J. M., Jaccard, J. J., & Baum, C. (2012) · Value in Health · doi:10.1016/j.jval.2012.08.2207 · Cited by 17
Hasler, W. L. (2002) · Medical Clinics of North America · doi:10.1016/s0025-7125(02)00086-x · Cited by 16
Consultation Liaison Psychiatry and Psychosomatics: Strange Bedfellows
Wise, T. N. (2000) · Psychotherapy and Psychosomatics · doi:10.1159/000012392 · Cited by 16
Hypnosis for non-cardiac chest pain
Palsson, O. S., & Whitehead, W. E. (2006) · Gut · doi:10.1136/gut.2006.095489 · Cited by 15
Self-citationSpetalen, S., Sandvik, L., Blomhoff, S., & Jacobsen, M. (2009) · Gastroenterology Research and Practice · doi:10.1155/2009/130684 · Cited by 15
“…Medicine, Rikshospitalet University Hospital, 0027 Oslo, Norway 4 Oestfold Hospital Trust, 1603 Fredrikstad, Norway, University of Oslo, 0316 Oslo, Norway and Norwegian University of Life Sciences, 1432 Ås, Norway Correspondence should be addressed to Signe Spetalen, spetale@online.no Received 8…”
InfluentialCerebral topography of rectal stimulation using single photon emission computed tomography
Bouras, E. P., O'Brien, T. J., Camilleri, M., O’Connor, M. K., & Mullan, B. P. (1999) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1999.277.3.g687 · Cited by 15
Distinct neurophysiological profiles in irritable bowel syndrome
Arebi, N., Bullas, D. C., Dukes, G. E., Gurmany, S., Hicks, K. J., Kamm, M. A., & Hobson, A. R. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00553.2010 · Cited by 14
Ohashi‐Doi, K., Gale, J. D., & Kurebayashi, Y. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.06.014 · Cited by 14
Perichondritis: a complication of piercing auricular cartilage
Yahalom, S., & Eliashar, R. (2003) · Postgraduate Medical Journal · doi:10.1136/pmj.79.927.29 · Cited by 14
Gastrointestinal motility and the brain‐gut axis
Ishiguchi, T., Itoh, H., & Ichinose, M. (2003) · Digestive Endoscopy · doi:10.1046/j.1443-1661.2003.00222.x · Cited by 14
Almansa, C., Agrawal, A. K., & Houghton, L. A. (2012) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.12.9 · Cited by 14
Kagan, J. (2002) · Disease Markers · doi:10.1155/1998/698239 · Cited by 1
Ringstrom, G., Sjovall, H., Simrén, M., & Ung, E. J. (2013) · Gastroenterology Nursing · doi:10.1097/sga.0000000000000011 · Cited by 13
“Furthermore, there is to date no drug or medical remedy that has been shown to cure IBS symptoms ( Kellow, Eckersley, & Jones, 1991 ; Whitehead & Palsson, 1998 ).”
BackgroundHobson, A. R., Chizh, B. A., Hicks, K. J., Aziz, Q., Worthen, S. F., Lawrence, P. J., Dewit, O., Boyle, Y., & Dukes, G. E. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00288.2009 · Cited by 13
Physiology of the Colon and Its Measurement
Bharucha, A. E., & Camilleri, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-40232-3.00144-8 · Cited by 13
Spetalen, S., Jacobsen, M., Vatn, M. H., Blomhoff, S., & Sandvik, L. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000037821.84014.66 · Cited by 13
“Several other sources may also impair agreement between test and retest, for example, the lack of a “conditioning” distension (6), the length of the interstimulus intervals (19), the subject’s psychological state ( 31 ), the body position (32), the phase of the menstruation cycle (33), and the time of day (34).”
What Does Pain or Discomfort in Irritable Bowel Syndrome Mean?
Handa, M., Nukina, H., Katsumi, A., & Kubo, C. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000026301.47638.92 · Cited by 13
“Psychological factors play an important role in determining where on the continuum of intensity of sensation IBS patients begin to report pain ( 17 ).”
BackgroundAbnormal Colonic Motility: A Possible Association With Urge Fecal Incontinence
Rodger, C. J., Nicol, L., Anderson, J. H., McKee, R. F., & Finlay, I. G. (2010) · Diseases of the Colon & Rectum · doi:10.1007/dcr.0b013e3181cc55cc · Cited by 12
Experimental Models of Stress and Pain: Do They Help to Develop New Therapies?
Bradesi, S., & Mayer, E. A. (2009) · Digestive Diseases · doi:10.1159/000268122 · Cited by 13
“(2) About 40–60p of IBS subjects show baseline hypersensitivity when this is defined as a pain or discomfort threshold to phasic distensions lower than the 95p confidence interval of a healthy control group [”
BackgroundRectal Distensibility and Symptoms After Stapled and Milligan–Morgan Operation for Hemorrhoids
Corsetti, M., Nardi, P. D., Pietro, S. D., Passaretti, S. M., Testoni, P. A., & Staudacher, C. (2009) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-009-0983-7 · Cited by 12
Preston, S. L., & Jankowski, J. A. (2006) · Gut · doi:10.1136/gut.2006.096461 · Cited by 12
Noninvasive bladder testing of adolescent females to assess visceral hypersensitivity
Tu, F. F., Hellman, K. M., Roth, G. E., Dillane, K. E., & Walker, L. S. (2021) · Pain · doi:10.1097/j.pain.0000000000002311 · Cited by 11
Sach, J., & Chang, L. (2002) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-002-0049-3 · Cited by 11
Challenges in drug development for functional gastrointestinal disorders. Part II: Visceral pain
Andresen, V., & Camilleri, M. (2006) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00779.x · Cited by 11
Adult-Age Inflammatory Pain Experience Enhances Long-Term Pain Vigilance in Rats
Li, S.-G., Wang, J., & Luo, F. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036767 · Cited by 10
“Hypervigilance to aversive stimuli is a hallmark of functional pain disorders [41].”
BackgroundBrain-gut interaction in irritable bowel syndrome
HARRIS, M. L., & Aziz, Q. (2003) · Hospital Medicine · doi:10.12968/hosp.2003.64.5.1757 · Cited by 10
Keefer, L., Taft, T., & Kiebles, J. L. (2012) · Wiley eBooks · doi:10.1002/9781118133880.hop209016 · Cited by 10
The difficult patient with constipation.
Müller-Lissner, S. (2007) · Best practice & research. Clinical gastroenterology · doi:10.1016/j.bpg.2007.01.008 · Cited by 11
Psychophysiologie des Eingeweideschmerzes
Musial, F. (2002) · Der Schmerz · doi:10.1007/s00482-002-0189-3 · Cited by 9
Wiklendt, L., Rosli, R. M., Kumar, R., Paskaranandavadivel, N., Bampton, P. A., Maslen, L., Costa, M., Brookes, S. J., O’Grady, G., & Dinning, P. G. (2023) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00114.2022 · Cited by 8
Assessment of Gastrointestinal Sensation – A Review
Hobson, A. R., & Aziz, Q. (2006) · Digestive Diseases · doi:10.1159/000092880 · Cited by 8
“Consequently, when sensory reports are used as primary end-points, the data are vulnerable to the inherent response bias of such an approach [”
Endometriosis and irritable bowel syndrome: a dilemma for the gynaecologist and gastroenterologist
Issa, B., Ormesher, L., Whorwell, P. J., Shah, M., & Hamdy, S. (2016) · The Obstetrician & Gynaecologist · doi:10.1111/tog.12241 · Cited by 8
What Can We Sense? Interoceptive Accuracy
Köteles, F. G. (2021) · Springer eBooks · doi:10.1007/978-3-030-63201-4_4 · Cited by 7
Pharmacology of Visceral Pain: Central Factors
Aziz, Q., Botha, C. A., & Willert, R. P. (2009) · Digestive Diseases · doi:10.1159/000268119 · Cited by 7
“This would indicate that VPH is specific to the viscera and is less likely to be due to reporting bias. Some investigators have suggested that these findings could be related to psychological factors in patients, leading to hyper-vigilance for visceral pain or response bias (a tendency to report lower intensity sensat…”
BackgroundLack of Association between Interleukin 12 C(-1188)A Polymorphism and Irritable Bowel Syndrome.
Barkhordari, E., Amirzargar, A. A., Ebrahimi-Daryani, N., Mahmoudi, M., Ansaripour, B., Alighardashi, M., Ahmadi-Ashtiani, H. R., Bashashati, M., & Rezaei, N. (2011) · Europe PMC (PubMed Central) · Cited by 7
Comorbidity Associated With Irritable Bowel Syndrome
Palsson, O. S., & Whitehead, W. E. (2005) · Psychiatric Annals · doi:10.3928/00485713-20050401-06 · Cited by 7
Self-citationNew concepts of irritable bowel syndrome
Mertz, H. R. (1999) · Current Gastroenterology Reports · doi:10.1007/s11894-999-0026-2 · Cited by 7
Psychologic therapies for irritable bowel syndrome
Boyce, P. M. (2001) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-001-0058-7 · Cited by 7
Treatment of Patients with Functional Esophageal Symptoms
Ringel, Y., & Drossman, D. A. (1999) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-199904000-00001 · Cited by 7
Simrén, M., Törnblom, H., Palsson, O. S., van Tilburg, M. A. L., Oudenhove, L. V., Tack, J. F., & Whitehead, W. E. (2016) · Gastroenterology · doi:10.1016/s0016-5085(16)30392-4 · Cited by 6
Self-citationPrinciples of motility and sensation testing
Kellow, J. E. (2003) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(03)00020-7 · Cited by 6
Role of functional brain imaging in gastroenterology in health and disease
Hobday, D. I., & Thompson, D. G. (2000) · Digestive and Liver Disease · doi:10.1016/s1590-8658(00)80393-x · Cited by 6
Some of the challenges in drug development for irritable bowel syndrome
Mayer, E. A. (2001) · Gut · doi:10.1136/gut.48.5.585 · Cited by 6
“If one accepts the concept that enhanced perception of visceral stimuli plays an important role in the pathophysiology of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders (and not everybody does!”
Bharucha, A. E. (2004) · doi:10.1002/9780470760307.ch13 · Cited by 6
Irritable bowel syndrome in children: new in diagnostics and treatment
Smirnova, G. I., Korsunskiy, A. A., & Vb, L. (2019) · Russian Pediatric Journal · doi:10.18821/1560-95612016-19-5-309-318 · Cited by 5
Physiology of the Colon and Its Measurement
Bharucha, A., & Camilleri, M. (2019) · Shackelford's Surgery of the Alimentary Tract, 2 Volume Set · doi:10.1016/b978-1-4377-2206-2.00141-x · Cited by 15
Visceral Hypersensitivity Is Not a Feature of Fibromyalgia Syndrome
Pace, F., Sarzi‐Puttini, P., Manzionna, G., Molteni, P., Turiel, M., Panni, B., & Bianchi-Porro, G. (2001) · Journal of Musculoskeletal Pain · doi:10.1300/j094v09n01_06 · Cited by 5
Brain-Gut-Achse: Stress und seine Wirkung auf den Verdauungstrakt
Moser, G. (2009) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 5
Entwicklungspsychopathologie rekurrierender Bauchschmerzen und somatoformer Störungen
Noeker, M., & Petermann, F. (2002) · Kindheit und Entwicklung · doi:10.1026//0942-5403.11.3.152 · Cited by 5
Irritable bowel syndrome (IBS): could we decide what is behind?
Bárdos, G. (2024) · Biologia Futura · doi:10.1007/s42977-024-00205-7 · Cited by 4
“Selective attention to gastrointestinal sensations and disease attribution may lie behind pain sensitivity (Whitehead and Palsson 1998).”
Josefsson, A., Törnblom, H., & Simrén, M. (2022) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm21214 · Cited by 4
“1,14,36 37-41 The phasic protocol has also shown a correlation with GI-symptom severity.”
Constipation and Functional Bowel Disorders
Varma, M., & Gurland, B. (2011) · Springer eBooks · doi:10.1007/978-1-4419-1584-9_32 · Cited by 3
Shapiro, M. S., & Olden, K. W. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01973.x · Cited by 4
Barostato rectal en el síndrome de intestino irritable
Claudia Defilippi, G., Quera, R., Ana María Madrid, S., Carlos Defilippi, C., & Jorge Valenzuela, E. (2006) · Revista médica de Chile · doi:10.4067/s0034-98872006001200005 · Cited by 3
Pathophysiology of Faecal Incontinence
Zorcolo, L., Bartolo, D. C. C., & Leroi, A. (2007) · Springer eBooks · doi:10.1007/978-88-470-0638-6_3 · Cited by 3
Talley, N. J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6189-2.00118-9 · Cited by 3
Brain‐to‐Gut Signaling: Central Processing
Hobson, A. R., & Aziz, Q. (2004) · Wiley eBooks · doi:10.1002/9780470760307.ch4 · Cited by 3
The Rectum: A Window to Irritable Bowel Syndrome?
Coremans, G., Azpiroz, F., Collins, S. M., Dapoigny, M. C., Müller-Lissner, S. A., Pace, F., Smout, A. J. P. M., Stockbrügger, R. W., & Whorwell, P. J. (2002) · Digestion · doi:10.1159/000063823 · Cited by 3
Irritable Bowel Syndrome (IBS) Concurrent with Fibromyalgia - Surprisingly Frequent
Palsson, O. S., & Moss, D. (2007) · Cited by 2
Self-citationTreating IBS in practice: a new aspect of care
Read, N. W., & Rampersad-Smith, L. (2013) · Practice Nursing · doi:10.12968/pnur.2013.24.11.538 · Cited by 2
Functional Symptoms in Gastroenterology: A Punch to the Gut
Srinath, A. I., Turner, S. A., & Szigethy, E. (2014) · Springer eBooks · doi:10.1007/978-1-4899-8074-8_5 · Cited by 3
Moser, G., & Peter, J. (2017) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2017.63.1.5 · Cited by 2
Irritable bowel syndrome in the general population : epidemiology, comorbidity and societal costs
Hillilä, M. T. (2010) · Työväentutkimus Vuosikirja · Cited by 2
Psychological Disturbances in Patients With Sphincter of Oddi Dysfunction
Kovács, Z., Kovács, F., & Pap, Á. (2005) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-005-7824-y · Cited by 2
“Not only the presence of psychiatric disorders, but also the more profound dysfunctional core beliefs and attitudes, for example, selective attention to gastrointestinal sensations and disease attribution, have a role in the presentation of symptoms, and also may account for the increased pain sensitivity observed in…”
BackgroundVidelock, E. J., & Chang, L. (2015) · Wiley eBooks · doi:10.1002/9781118512074.ch75 · Cited by 2
Sturgis, E. T. (2003) · Springer eBooks · doi:10.1007/978-1-4757-4963-2_13 · Cited by 2
Choi, C. H. (2010) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2010.16.4.450 · Cited by 1
Epidemiology, pathogenesis and treatment of irritable bowel syndrome
Nam, J. H., Alnoah, Z., Yenumula, S. R., & Murthy, S. (2003) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.13.8.1213 · Cited by 1
“, however, have challenged this interpretation [64].”
Abnormal anorectal manometric and sensory functions in patients with functional anorectal pain
Zheng, H., Wu, Y., Wu, S., Liu, F., Chen, J. D. Z., Chai, D., & Ni, M. (2025) · BMC Gastroenterology · doi:10.1186/s12876-025-04084-7 · Cited by 1
“…reported that the majority of patients with functional defecation disorders had anal levator muscle pressure pain and that their defecation disorders were improved with biofeedback treatment, suggesting that rectoanal incoordination of defecation is the pathophysiology of levator ani syndrome [37].”
Pearson, J. (2016) · Gastroenterology & Hepatology Open Access · doi:10.15406/ghoa.2016.05.00166 · Cited by 1
Approach to a Child with Irritable Bowel Syndrome: A Review
Rukunuzzaman, M., Karim, A. B., Mazumder, W., Nurullah, M., Hussain, F., & Sultana, K. (2017) · Journal of National Institute of Neurosciences Bangladesh · doi:10.3329/jninb.v2i1.32969 · Cited by 1
Pelvic Pain: Clinical Features
Ricci, G., Lorenzo, G. D., Zito, G., Franzò, S., & Romano, F. (2019) · Springer eBooks · doi:10.1007/978-3-319-99822-0_20 · Cited by 1
The Efficacy of Interpretation Bias Modification Program for Pain Outcomes
Park, H., & Cho, S. (2020) · Korean Journal of Stress Research · doi:10.17547/kjsr.2020.28.2.51 · Cited by 1
Hypnotherapy for functional gastrointestinal disorders
(2005) · Drug and Therapeutics Bulletin · doi:10.1136/dtb.2005.43645 · Cited by 1
Investigation of Fecal Incontinence
Bharucha, A. E. (2008) · Medical radiology · doi:10.1007/978-3-540-71968-7_15 · Cited by 1
“Thresholds for fi rst perception, desire to defecate, and severe urgency are measured during distension ( Whitehead and Palsson 1998 ).”
BackgroundGrundkonzepte der gastrointestinalen Psychophysiologie
Cuntz, U. (2014) · Verhaltenstherapie · doi:10.1159/000362913 · Cited by 1
Peripheral and central factors in the pathophysiology of irritable bowel syndrome
Posserud, I. (2007) · Gothenburg University Publications Electronic Archive (Gothenburg University) · Cited by 1
Central Nervous System Approaches for Treating Functional Disorders: How, When, and Why?
Clouse, R. E. (2004) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200406003-00023 · Cited by 1
Editor’s Preamble:The Nature of IBS and the Need for a Psychological Approach
Palsson, O. S. (2005) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207140500322917 · Cited by 1
“Studies in that area (reviewed in Whitehead & Palsson, 1998 ) indicate that approximately two thirds of IBS patients have abnormally low thresholds for pain in their bowels.”
BackgroundSelf-citationWassom, M. C. (2008) · KU ScholarWorks (The University of Kansas) · Cited by 1
NEM-SPECIFIKUS EGÉSZSÉGPROBLÉMÁK HÁTTERE ÉS LEHETSÉGES MODELLJEI
Bárdos, G. (2008) · REAL-d (Hungarian Academy of Sciences) · Cited by 1
Metcalf, A. M., & Ross, H. M. (2007) · Springer eBooks · doi:10.1007/978-0-387-36374-5_48 · Cited by 1
Irritable bowel syndrome in Norway
Vandvik, P. O. (2006) · BIBSYS Brage (BIBSYS (Norway)) · Cited by 1
Ringström, G. (2008) · Gothenburg University Publications Electronic Archive (Gothenburg University)
A psychosocial perspective on pediatric functional abdominal pain: risk factors and treatment
van der Veek, S. (2012) · UvA-DARE (University of Amsterdam)
An unusual case of hepatosplenomegaly
Chan, C., Lunniss, P., Wang, D.-L., Williams, N., & Scott, S. (2005) · Gut · doi:10.1136/gut.2005.064824 · Cited by 82
Posibilidades farmacológicas de modulación de la percepción visceral
Juan, A. P., & Mearin, F. (2004) · Gastroenterología y Hepatología · doi:10.1016/s0210-5705(03)70508-1
Dreams: The royal road to the intestines?
Guthrie, E. (2002) · Digestive and Liver Disease · doi:10.1016/s1590-8658(02)80103-7
Rutkowska, D., Piątek, J., Tokura, H., Linke, K., Takasu, N., Inatsugi, N., & Torlińska, T. (2006) · Biological Rhythm Research · doi:10.1080/15730620500386594
“The observed symptoms are the result of both: abnormal intestinal motility and enhanced visceral sensitivity (Kay et al. 1998; Whitehead & Palsson 1998; Camilleri 1999a; Schmulson & Chang 1999).”
Complication of Waldenströem’s macroglobulinaemia following ERCP: Figure 1
Pascu, M., Hanke, B., Wiedenmann, B. J., Martens, F., & Dignass, A. U. (2004) · Gut · doi:10.1136/gut.2003.031211
Simptomatologia psicològica relatada per pacients amb trastorns gastrointestinals funcionals
Tomás, P., & Lamo, D. (2006)
Mendoza, A. C., Rios, R. D., Alva, E. A., Vásquez Valverde, N., & Morales, C. C. (2012) · Americanae (AECID Library) · doi:10.47892/rgp.2012.322.278
Controlled trial of hypnotherapy as a treatment for irritable bowel syndrome.
Phillips-Moore, J. (2009) · The Sydney eScholarship Repository (The University of Sydney)
Psychological Co-morbidities of Irritable Bowel Syndrome
Keefer, L., Kiebles, J. L., & Taft, T. (2011) · Springer eBooks · doi:10.1007/978-1-4419-0029-6_10
Irritable Bowel Syndrome : Studies of central pathophysiological mechanisms and effects of treatment
Lowén, M. (2015) · Linköping University medical dissertations · doi:10.3384/diss.diva-122144
Walter, S. (2006) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Implementation of Gut-Directed Hypnotherapy for Irritable Bowel Syndrome In Clinical Practice
Lindfors, P. (2012) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Sotoudehmanesh, R., Akram, A., Khatibian, M., Movahedi, Z., & Heidari, Z. (2011) · GOVARESH
Metadata
- Authors
- WHITEHEAD, W., & PALSSON, O.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Eastern Virginia Medical School (US)
- ORCID
- PALSSON, O
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 1998-11
- Volume
- 115
- Issue
- 5
- Pages
- 1263-1271
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2150287168
- Cited by
- 314
- References
- 85
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 5 · 2018: 4 · 2017: 4 · 2016: 12 · 2015: 10 · 2014: 8 · 2013: 6 · 2012: 10
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- National Institutes of Health (2k05mh000133-17)
- National Institute of Mental Health (KO5 MH00133)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK031369, R01 DK31369)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Keywords
- irritable bowel syndrome, pain threshold, rectal distension, hyperalgesia, anxiety, depression, stress, sensitization, neuroimaging, selective attention, disease attribution, biomarkers
- MeSH terms
- Colonic Diseases, Functional, Humans, Pain, Rectum, Biomarkers, Pain Threshold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
