Cited by 623Inflammatory Bowel DiseaseOcular Diseases and Behçet’s SyndromeColorectal Cancer Screening and Detection

The DOI matches its Crossref record; 34 of the 35 references it cites were found in a registry or an index.

Crohn's disease in Olmsted County, Minnesota, 1940–1993: Incidence, prevalence, and survival

Open access

Loftus, Edward V., Silverstein, Marc D., Sandborn, William J., Tremaine, William J., Harmsen, W.Scott, Zinsmeister, Alan R.·1998·Gastroenterology

DOI 10.1016/s0016-5085(98)70421-4

Open this paper in CoChat — free account Open PDF

Abstract

Background & aims Many centers worldwide have reported an increased incidence of Crohn's disease, but population-based data in North America are sparse. We studied the incidence and prevalence of Crohn's disease in Olmsted County, Minnesota, and examined temporal trends in incidence and survival.Methods Residents diagnosed with Crohn's disease between 1970 and 1993 were incidence cases, and residents with Crohn's disease who were alive on January 1, 1991, were prevalence cases. Cases from previous studies were reconfirmed. Rates were adjusted using 1990 U.S. Census figures for whites. Incidence trends were evaluated with a Poisson regression model. Survival from diagnosis was compared with that expected for U.S. north-central whites.Results Between 1940 and 1993, 225 incidence cases were identified, for an adjusted incidence rate of 5.8 per 100,000 person-years. On January 1, 1991, there were 145 residents with Crohn's disease, an adjusted prevalence rate of 133 per 100,000, 46% higher than that seen in 1980. Incidence rates before 1964 were significantly lower than those of 1989-1993. Observed survival was less than expected (P = 0.007).Conclusions The incidence of Crohn's disease has stabilized since the 1970s at a rate higher than that seen previously. Prevalence has increased by 46% since 1980. Overall survival is slightly decreased.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/s0016-5085(98)70421-4

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

History of the Rochester Epidemiology Project
Melton, L. J. (1996) · Mayo Clinic Proceedings · doi:10.4065/71.3.266 · Cited by 1,443
Inflammatory Bowel Disease
Podolsky, D. K. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109263251306 · Cited by 1,226
Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD).
Shivananda, S., Lennard‐Jones, J. E., Logan, R. F., Fear, N. T., Price, A. B., Carpenter, L., & BLANKENSTEIN, M. V. (1996) · Gut · doi:10.1136/gut.39.5.690 · Cited by 1,024
The Patient Record in Epidemiology
Kurland, L. T., & Molgaard, C. A. (1981) · Scientific American · doi:10.1038/scientificamerican1081-54 · Cited by 780
Increased risk of large-bowel cancer in Crohn's disease with colonic involvement
Ekbom, A., Adami, H., Helmick, C. G., & Zack, M. M. (1990) · The Lancet · doi:10.1016/0140-6736(90)91889-i · Cited by 698
The epidemiology of inflammatory bowel disease: A large, population-based study in Sweden
Ekbom, A., Helmick, C. G., Zack, M. M., & Adami, H. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90202-v · Cited by 436
Intestinal cancer risk and mortality in patients with Crohn's disease
Munkholm, P., Langholz, E., Davidsen, M., & Binder, V. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)91068-s · Cited by 379
Incidence and Prevalence of Crohn's Disease in the County of Copenhagen, 1962-87: A Sixfold Increase in Incidence
Munkholm, P. S., Langholz, E., Nielsen, O. H., Kreiner, S., & Binder, V. (1992) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529209000127 · Cited by 300
Digestive diseases in the United States: Epidemiology and impact
Locke, G. R. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90479-4 · Cited by 298
Geographic variation of inflammatory bowel disease within the United States
Sonnenberg, A., McCarty, D. J., & Jacobsen, S. J. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90594-b · Cited by 283

Show all 35 references

Research works printed but not linked: 2

Bernstein, 1997, The high prevalence of Crohn's disease in a central Canadian province: a population-based epidemiologic study (abstr), Gastroenterology, 112, A932
Loftus, 1997, Incidence and prevalence of ulcerative colitis in Olmsted County, Minnesota, 1970–1993 (abstr), Gastroenterology, 112, A1027

Sorted by citations

Items 301–400 of 622

Pharmacogenomics of Response to Anti-Tumor Necrosis Factor Therapy in Patients with Crohn???s Disease
Shetty, A., & Forbes, A. (2002) · American Journal of PharmacoGenomics · doi:10.2165/00129785-200202040-00001 · Cited by 35
Effects of Malva sylvestris and Its Isolated Polysaccharide on Experimental Ulcerative Colitis in Rats
Hamedi, A., Rezaei, H., Azarpira, N., Jafarpour, M., & Ahmadi, F. (2015) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587215589184 · Cited by 34
Incidence of inflammatory bowel disease in the province of Styria, Austria, from 1997 to 2007: A population-based study
Petritsch, W., Fuchs, S. C. P. C., Berghold, A., Bachmaier, G., Högenauer, C., Hauer, A. C., Weiglhofer, U., & Wenzl, H. (2012) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2012.03.012 · Cited by 36
Inflammatory Bowel Disease in the Elderly
Hussain, S. W., & Pardi, D. S. (2010) · Drugs & Aging · doi:10.2165/11537340-000000000-00000 · Cited by 34
Certolizumab pegol for the management of Crohn's disease in adults
Rivkin, A. M. (2009) · Clinical Therapeutics · doi:10.1016/j.clinthera.2009.06.015 · Cited by 34
Therapeutic modulation of gut microbiota in inflammatory bowel disease: More questions to be answered
Qiao, Y., Cai, C., & Ran, Z. H. (2016) · Journal of Digestive Diseases · doi:10.1111/1751-2980.12422 · Cited by 36
Inflammatory Bowel Disease in the Elderly
Picco, M. F., & Cangemi, J. R. (2009) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2009.06.006 · Cited by 34
A Clustering of Crohn's Disease in Mankato, Minnesota
Kruiningen, H. J. V., & Freda, B. J. (2001) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200102000-00004 · Cited by 34
Intestinal responsiveness to experimental colitis in young rats is altered by maternal diet
Jacobson, K., Mundra, H. K., & Innis, S. M. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00459.2004 · Cited by 33
Treatment of Inflammatory Bowel Disease in the Elderly
Pardi, D. S., Loftus, E. V., & Camilleri, M. (2002) · Drugs & Aging · doi:10.2165/00002512-200219050-00004 · Cited by 34
Self-citation
Structural and functional changes in the brain of patients with Crohn’s disease: an activation likelihood estimation meta-analysis
Yeung, A. W. K. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00291-w · Cited by 33
Diagnostic delay in patients with inflammatory bowel disease in Austria
Austrian IBD Study Group (ATISG), Novacek, G., Gröchenig, H. P., Haas, T., Wenzl, H., Steiner, P., Koch, R., Feichtenschlager, T., Eckhardt, G., Mayer, A., et al. (2019) · Wiener klinische Wochenschrift · doi:10.1007/s00508-019-1451-3 · Cited by 32
Crohnʼs Disease runs a more aggressive course in young asian patients
Thia, K. T. J., Luman, W., & Jin, O. C. (2005) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000195390.11645.7d · Cited by 32
Challenges in IBD Research: Updating the Scientific Agendas
Elson, C. O., Sartor, R. B., Targan, S. R., & Sandborn, W. J. (2003) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200305000-00001 · Cited by 31
Self-citation
Temporal Change in Phenotypic Behaviour in Patients with Crohn’s Disease: Do Indian Patients Behave Differently from Western and Other Asian Patients?
Kalaria, R., Desai, D., Abraham, P., Joshi, A. G., Gupta, T., & Shah, S. R. (2015) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjv202 · Cited by 30
Lack of Difference in Treatment Patterns and Clinical Outcomes Between Black and White Patients With Inflammatory Bowel Disease
Barnes, E. L., Kochar, B. D., Long, M. D., Pekow, J. R., Ananthakrishnan, A. N., Anyane‐Yeboa, A., Martin, C. F., Galanko, J. A., Herfarth, H. H., Kappelman, M. D., et al. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy179 · Cited by 32
Overall and Cause-Specific Mortality of Inflammatory Bowel Disease in Olmsted County, Minnesota, From 1970 Through 2016
Aniwan, S., Harmsen, W. S., Tremaine, W. J., Kane, S. V., & Loftus, E. V. (2018) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2018.03.004 · Cited by 31
Self-citation
Clinical Outcomes and Management of Inflammatory Bowel Disease in the Older Patient
Ha, C. Y., & Katz, S. (2013) · Current Gastroenterology Reports · doi:10.1007/s11894-012-0310-4 · Cited by 29
Mycobacterium avium subsp paratuberculosis—Incidences in milk and milk products, their isolation, enumeration, characterization, and role in human health
Patel, A. R., & Shah, N. (2011) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2011.04.009 · Cited by 30
Is Salt at Fault? Dietary Salt Consumption and Inflammatory Bowel Disease
Kuang, R. R., O’Keefe, S. J., Rivers, C. R., Koutroumpakis, F., & Binion, D. G. (2022) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izac058 · Cited by 37
Epidemiology of inflammatory bowel disease among an indigent multi-ethnic population in the United States
Malaty, H. M., Thuimepohi, S., & Hou, J. K. (2010) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s14586 · Cited by 31
Incidence of Spondyloarthropathy in Patients with Ulcerative Colitis: A Population-based Study
Shivashankar, R., Loftus, E. V., Tremaine, W. J., Harmsen, W. S., Zinsmeister, A. R., & Matteson, E. L. (2013) · The Journal of Rheumatology · doi:10.3899/jrheum.121029 · Cited by 30
Self-citation
Genetics of inflammatory bowel disease
Taylor, K. D., Rotter, J. I., & Huiying, Y. (2007) · Springer eBooks · doi:10.1007/0-387-25808-6_3 · Cited by 30
Analysis of Serum Antibodies in Patients Suspected of Having Inflammatory Bowel Disease
Jaskowski, T. D., Litwin, C. M., & Hill, H. R. (2006) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00034-06 · Cited by 30
Global Epidemiology and Burden of Elderly-Onset Inflammatory Bowel Disease: A Decade in Review
Danpanichkul, P., Suparan, K., Arayakarnkul, S., Jaroenlapnopparat, A., Polpichai, N., Fangsaard, P., Kongarin, S., Srisurapanont, K., Sukphutanan, B., Wanchaitanawong, W., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12155142 · Cited by 29
Racial and Ethnic Disparities in Patients With Inflammatory Bowel Disease: An Online Survey
Shah, S. B., Shillington, A. C., Kabagambe, E. K., Deering, K. L., Babin, S. F., Capelouto, J. A., Pulliam, C., Patel, A. A., LaChappelle, B. J., & Liu, J. C. (2023) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izad194 · Cited by 29
Epidemiologic features of ınflammatory bowel disease in Western Blacksea region of Turkey for the last 10 years: retrospective cohort study
Can, G., Poşul, E., Yılmaz, B., Can, H., Korkmaz, U., Ermış, F., Kurt, M., & Dağlı, Ü. (2018) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2015.310 · Cited by 29
Preclinical Serological Signatures are Associated With Complicated Crohn’s Disease Phenotype at Diagnosis
Choung, R. S., Petralia, F., Torres, J., Ungaro, R. C., Porter, C., Sato, T., Telesco, S., Strauss, R. S., Plevy, S. E., Princen, F., et al. (2023) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2023.01.033 · Cited by 28
A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology
Helbig, K. L., Nothnagel, M., Hampe, J., Balschun, T. C., Nikolaus, S., Schreiber, S., Franke, A., & Nöthlings, U. (2012) · BMC Medical Genetics · doi:10.1186/1471-2350-13-14 · Cited by 29
The Relation Between NOD2/CARD15 Mutations and the Prevalence and Phenotypic Heterogeneity of Crohn’s Disease: Lessons from the Israeli Arab Crohn’s Disease Cohort
Karban, A. A., Atia, O., Leitersdorf, E., Shahbari, A., Sbeit, W., Ackerman, Z., Mualem, R., Levine, A., Nesher, S., Safadi, R., et al. (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-2917-x · Cited by 29
Colorectal cancer risk in ulcerative colitis: an updated population-based systematic review and meta-analysis
Zhang, L., Zhang, X., Su, T., Xiao, T., Xu, H., & Zhao, S. (2025) · EClinicalMedicine · doi:10.1016/j.eclinm.2025.103269 · Cited by 31
Early‐onset Crohn Disease Is Associated With Male Sex and a Polymorphism in the IL‐6 Promoter
Sagiv-Friedgut, K., Karban, A. A., Weiss, B., Shaoul, R. R., Shamir, R., Bujanover, Y., Reif, S. S., Boaz, M., Inbar, S., Levine, A., et al. (2009) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181b7a6a4 · Cited by 28
The Association of Inflammatory Gut Diseases with Neuroinflammatory and Auditory Disorders
Kociszewska, D., & Vlajkovic, S. M. (2022) · Frontiers in Bioscience-Elite · doi:10.31083/j.fbe1402008 · Cited by 29
Efficacy of Vedolizumab in a Nationwide Cohort of Elderly Inflammatory Bowel Disease Patients
Khan, N. H., Pernes, T., Weiss, A., Trivedi, C. P., Patel, M., Medvedeva, E. L., Xie, D., & Yang, Y. (2021) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izab163 · Cited by 26
Racial and Ethnic Distribution of Inflammatory Bowel Disease in the United States
Barnes, E. L., Nowell, W. B., Venkatachalam, S., Dobes, A., & Kappelman, M. D. (2021) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izab219 · Cited by 28
Plasma concentrations of perfluoroalkyl substances and risk of inflammatory bowel diseases in women: A nested case control analysis in the Nurses’ Health Study cohorts
Lochhead, P. J., Khalili, H., Ananthakrishnan, A. N., Burke, K. E., Richter, J. M., Sun, Q., Grandjean, P., & Chan, A. T. (2021) · Environmental Research · doi:10.1016/j.envres.2021.112222 · Cited by 27
Antisecretory factor as a potential health-promoting molecule in man and animals
Ulgheri, C., Paganini, B., & Rossi, F. (2010) · Nutrition Research Reviews · doi:10.1017/s0954422410000193 · Cited by 26
Detection of DNA hypermethylation in sera of patients with Crohn’s disease
Bae, J., Park, J., Yang, K., KIM, T.-O., & Yi, J. M. (2013) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1840 · Cited by 27
Management of the Elderly Patients with Inflammatory Bowel Disease
Katz, S., Surawicz, C. M., & Pardi, D. S. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e31828c8536 · Cited by 26
Emerging prognostic markers to determine Crohn's disease natural history and improve management strategies: a review of recent literature.
Lichtenstein, G. R. (2010) · PubMed Central · Cited by 26
Diagnostic Medical Radiation in Inflammatory Bowel Disease
Swanson, G. R., Behara, R., Braun, R., & Keshavarzian, A. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e31828dc6b6 · Cited by 25
Randomised clinical trial: safety, pharmacokinetics and pharmacodynamics of trazpiroben (TAK‐906), a dopamine D2/D3 receptor antagonist, in patients with gastroparesis
Kuo, B., Scimia, C., Dukes, G. E., Zhang, W., Gupta, S., Chen, C., Chuang, E., & Camilleri, M. (2021) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.16451 · Cited by 26
Crohn’s disease: why the disparity in mortality?: Table 1
Loftus, E. V. (2006) · Gut · doi:10.1136/gut.2005.080283 · Cited by 25
Self-citation
Epidemiology supports oral contraceptives as a risk factor in Crohn's disease: Figure 1
Alic, M. (2000) · Gut · doi:10.1136/gut.46.1.140 · Cited by 25
Adalimumab for Crohn’s disease after infliximab treatment failure
Da, W., Zhu, J.-S., Wang, L., & Lu, Y. (2013) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e32836220ab · Cited by 24
Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs
Alrubia, S., Mao, J., Chen, Y., Barber, J., & Rostami‐Hodjegan, A. (2022) · Clinical Pharmacokinetics · doi:10.1007/s40262-022-01169-4 · Cited by 25
Clinical Activity and Quality of Life Indices Are Valid Across Ulcerative Colitis But Not Crohn’s Disease Phenotypes
Taleban, S., Stewart, K. O., Li, D. K., Singh, P., Pardi, D. S., Sturgeon, H. C., Yajnik, V., Xavier, R. J., Ananthakrishnan, A. N., & Khalili, H. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4180-8 · Cited by 24
Malignant peritoneal mesothelioma and Crohn disease
Butnor, K. J., Pavlisko, E. N., Sporn, T. A., & Roggli, V. L. (2016) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2016-203945 · Cited by 24
Epidemiology of Inflammatory Bowel Disease
Bernstein, C. N., & Blanchard, J. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-311-8_2 · Cited by 24
A risk-profiling approach for surveillance of inflammatory bowel disease-colorectal carcinoma is more cost-effective: a comparative cost-effectiveness analysis between international guidelines
Lutgens, M. W. M. D., van Oijen, M. G. H., Mooiweer, E., van der Valk, M. E., Vleggaar, F. P., Siersema, P. D., & Oldenburg, B. (2014) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2014.02.1031 · Cited by 23
Inflammatory Bowel Disease in the Baby to Baby Boomer: Pediatric and Elderly Onset of IBD
Afzali, A., & Katz, S. (2018) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-018-0188-9 · Cited by 23
Crohn’s disease incidence evolution in North-western Greece is not associated with alteration of NOD2/CARD15 variants
Economou, M. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i38.5116 · Cited by 23
Natural History of Crohnʼs Disease in Elderly Patients Diagnosed Over the Age of 70 Years
Fuméry, M., Pariente, B., Sarter, H., Charpentier, C., Armengol‐Debeir, L., Dupas, J., Coevoet, H., Peyrin‐Biroulet, L., D’Agay, L., Gower‐Rousseau, C., et al. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000821 · Cited by 22
Long-Term Outcomes of Infliximab Treatment in 582 Korean Patients with Crohn’s Disease: A Hospital-Based Cohort Study
Park, S. H., Hwang, S. W., Kwak, M. S., Kim, W. S., Lee, J.-M., Lee, H., Yang, D., Kim, K., Ye, B. D., Byeon, J., et al. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4105-6 · Cited by 22
Changes in the Long-term Prognosis of Crohn’s Disease between 1986 and 2015: The Population-Based Songpa-Kangdong Inflammatory Bowel Disease Cohort Study
Ye, B. D., Hong, S. N., Seo, S. I., Kim, Y., Cha, J. M., Rhee, K. H., Yoon, H., Kim, Y., Kim, K. H., Park, S., et al. (2021) · Gut and Liver · doi:10.5009/gnl210044 · Cited by 21
A claims‐based Markov model for Crohn’s disease
Malone, D., Waters, H. C., Bos, J. V. D., Popp, J. W., Draaghtel, K., & Rahman, M. I. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04356.x · Cited by 21
Endogenous Levels of Circulating Androgens and Risk of Crohnʼs Disease and Ulcerative Colitis Among Women
Khalili, H., Ananthakrishnan, A. N., Konijeti, G. G., Higuchi, L. M., Fuchs, C. S., Richter, J. M., Tworoger, S. S., Hankinson, S. E., & Chan, A. T. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000385 · Cited by 21
Lack of Utility of Symptoms and Signs at First Presentation as Predictors of Inflammatory Bowel Disease in Secondary Care
Ford, A. C., Moayyedi, P., Berčík, P., Morgan, D. G., Bolino, C., Pinto-Sánchez, M. I., & Reinisch, W. (2015) · The American Journal of Gastroenterology · doi:10.1038/ajg.2015.117 · Cited by 22
Do Black and Hispanic Americans With Inflammatory Bowel Disease (IBD) Receive Inferior Care Compared With White Americans? Uneasy Questions and Speculations
Jackson, J. F., & Kornbluth, A. A. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01371.x · Cited by 22
Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: Evidence for enhanced pathogenicity of Mycobacterium avium subspecies paratuberculosis
Basler, T., Geffers, R., Weiß, S., Valentin‐Weigand, P., & Goethe, R. (2008) · Immunobiology · doi:10.1016/j.imbio.2008.07.009 · Cited by 21
Treatment of luminal and fistulizing Crohn's disease with infliximab
Comerford, L. W., & Bickston, S. J. (2004) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2004.02.014 · Cited by 21
Treatment of Crohn's Disease at the Turn of the Century
Bickston, S. J., & Cominelli, F. (1998) · New England Journal of Medicine · doi:10.1056/nejm199808063390610 · Cited by 21
Incidence of and Risk Factors for Free Bowel Perforation in Patients with Crohn’s Disease
Kim, J. W., Lee, H., Ye, B. D., Yang, S., Hwang, S. W., Park, S. H., Yang, D., Kim, K., Byeon, J., Myung, S., et al. (2017) · Digestive Diseases and Sciences · doi:10.1007/s10620-017-4539-5 · Cited by 20
Incidence of Infections and Malignancy Among Elderly Male Patients with IBD Exposed to Vedolizumab, Prednisone, and 5-ASA Medications: A Nationwide Retrospective Cohort Study
Khan, N. H., Pernes, T., Weiss, A., Trivedi, C. P., Patel, M., Xie, D., & Yang, Y. (2021) · Advances in Therapy · doi:10.1007/s12325-021-01713-x · Cited by 20
Combined Endoscopic and Radiologic Healing Is Associated With a Better Prognosis Than Endoscopic Healing Only in Patients With Crohn's Disease Receiving Anti-TNF Therapy
Oh, K., Oh, E. H., Noh, S. M., Park, S. H., Kim, N., Hwang, S. W., Park, S. H., Yang, D., Byeon, J., Myung, S., et al. (2022) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000442 · Cited by 20
Estimating Rare Disease Prevalence From Administrative Hospitalization Databases
Ward, M. M. (2005) · Epidemiology · doi:10.1097/01.ede.0000153643.88019.92 · Cited by 20
Prescribing Patterns and Awareness of Adverse Effects of Infliximab: A Health Survey of Gastroenterologists
Donovan, M., Lunney, K. M., Carter‐Pokras, O., & Cross, R. K. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9269-z · Cited by 20
The Association between Race and Crohn's Disease Phenotype in the Western Cape Population of South Africa, Defined by the Montreal Classification System
Basson, A. R., Swart, R., Jordaan, E., Mazinu, M., & Watermeyer, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104859 · Cited by 20
Trends of inflammatory bowel disease at a tertiary care center in northern India
Sood, A., Kaur, K., Singh, A., Midha, V., Mahajan, R., Bansal, N., Mehta, V., & Singh, D. (2020) · Intestinal Research · doi:10.5217/ir.2020.00010 · Cited by 19
Assessing Drug Treatment Preferences of Patients with Crohnʼs Disease
Lichtenstein, G. R., Waters, H. C., Kelly, J., McDonald, S., Zanutto, E. L., Hendricks, D. A., & Rahman, M. I. (2010) · Patient · doi:10.2165/11314880-000000000-00000 · Cited by 20
Insurance problems among inflammatory bowel disease patients: results of a Dutch population based study
Rüssel, M. G. (2003) · Gut · doi:10.1136/gut.52.3.358 · Cited by 19
Treatment of Crohn’s Disease with Leflunomide as Second-Line Immunosuppression
Holtmann, M. H., Gerts, A., Weinmann, A., Galle, P. R., & Neurath, M. F. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-007-9953-7 · Cited by 19
Inflammatory bowel diseases in children
Kim, S. S. Y., & Ferry, G. D. (2002) · Current problems in pediatric and adolescent health care · doi:10.1067/mps.2002.122638 · Cited by 19
13-year mortality trends among hospitalized patients with inflammatory bowel disease
Sewell, J. L., & Yee, H. F. (2012) · BMC Gastroenterology · doi:10.1186/1471-230x-12-79 · Cited by 18
Costs of adalimumab versus infliximab as first-line biological therapy for luminal Crohn's disease
Choi, G. K. H., Collins, S. D. E., Greer, D., Warren, L. R., Dowson, G., Clark, T., Hamlin, P. J., & Ford, A. C. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.09.017 · Cited by 18
Inflammatory bowel disease and asthma: A population-based, case-control study
Fenta, Y. A., Tello, N., Jung, J. A., Urm, S.-H., Loftus, E. V., Yawn, B. P., Li, X., & Juhn, Y. J. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21277 · Cited by 18
Self-citation
Colonoscopy-guided therapy for the prevention of post-operative recurrence of Crohn’s disease
Cândia, R., Bravo‐Soto, G., Monrroy, H., Hernández-Rocha, C., & Nguyen, G. C. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012328.pub2 · Cited by 17
Cumulative Length of Bowel Resection in a Population-Based Cohort of Patients With Crohn’s Disease
Peyrin‐Biroulet, L., Harmsen, W. S., Tremaine, W. J., Zinsmeister, A. R., Sandborn, W. J., & Loftus, E. V. (2016) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2016.04.031 · Cited by 17
Self-citation
Application of Polymeric Nano-Materials in Management of Inflammatory Bowel Disease
Minakshi, P., Kumar, R., Ghosh, M., Brar, B., Barnela, M., & Lakhani, P. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200320113322 · Cited by 17
Measles Vaccination and Inflammatory Bowel Disease
Davis, R. L., & Bohlke, K. (2001) · Drug Safety · doi:10.2165/00002018-200124130-00001 · Cited by 17
Crohn′s disease in a Saudi outpatient population: Is it still rare?
Mofleh, I. A. A., Almofarreh, M., Al-Teimi, I. N., & Aljebreen, A. (2009) · Saudi Journal of Gastroenterology · doi:10.4103/1319-3767.45357 · Cited by 16
Black and White Patients With Inflammatory Bowel Disease Show Similar Biologic Use Patterns With Medicaid Insurance
Barnes, E. L., Bauer, C. M., Sandler, R. S., Kappelman, M. D., & Long, M. D. (2020) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaa090 · Cited by 21
Mortality in inflammatory bowel disease: peril and promise
Loftus, E. V. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.10.020 · Cited by 16
Self-citation
Is There a Link Between H. Pylori and the Epidemiology of Crohn’s Disease?
Shah, A., Talley, N. J., Walker, M. M., Koloski, N. A., Morrison, M., Burger, D. C., Andrews, J. M., McGuckin, M. A., Jones, M., & Holtmann, G. (2017) · Digestive Diseases and Sciences · doi:10.1007/s10620-017-4496-z · Cited by 17
A model of an inflammatory bowel disease population-based registry: The Forlì experience (1993–2013)
Valpiani, D., Manzi, I., Mercuriali, M., Giuliani, O., Ravaioli, A., Colamartini, A., Bucchi, L., Falcini, F., & Ricci, E. (2017) · Digestive and Liver Disease · doi:10.1016/j.dld.2017.09.120 · Cited by 16
Crohn's Disease Is Associated with Polymorphism of CARD15/NOD2 Gene in a Hungarian Population
NAGY, Z., Karádi, O., Rumi, G., Rumi, G., Pár, A., Mózsik, G., Czirják, L., & Sütő, G. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1361.045 · Cited by 16
Long-Term Outcomes of Adalimumab Treatment in 254 Patients with Crohn’s Disease: A Hospital-Based Cohort Study from Korea
Seo, H., Ye, B. D., Song, E. M., Lee, S.-H., Chang, K., Lee, H., Hwang, S. W., Park, S. H., Yang, D., Kim, K., et al. (2017) · Digestive Diseases and Sciences · doi:10.1007/s10620-017-4715-7 · Cited by 15
Neurovasculature of high and low tie ligation of the inferior mesenteric artery
Campbell, A., MacDonald, A. W., Oliphant, R., Russell, D., & Fogg, Q. A. (2018) · Surgical and Radiologic Anatomy · doi:10.1007/s00276-018-2092-3 · Cited by 15
Association between psoriasis, psoriatic arthritis and gastrointestinal disease
Yousaf, A., Raiker, R., Davis, S. M., Gayam, S., & Zinn, Z. A. (2020) · Wiener klinische Wochenschrift · doi:10.1007/s00508-020-01740-8 · Cited by 15
[Epidemiology of inflammatory bowel disease: controversies in classical epidemiology].
Sicilia, B., Vicente, R., & Gomollón, F. (2009) · PubMed · Cited by 15
Effects of Perianal Involvement on Clinical Outcomes in Crohn's Disease over 10 Years
Yoon, J. Y., Cheon, J. H., Park, S. J., Kim, T. I., & Kim, W. H. (2017) · Gut and Liver · doi:10.5009/gnl17275 · Cited by 15
The mouth in inflammatory bowel disease and aspects of orofacial granulomatosis
Hullah, E. A., & Escudier, M. P. (2019) · Periodontology 2000 · doi:10.1111/prd.12264 · Cited by 15
Incidence and risk factors of Pneumocystis jirovecii pneumonia in Korean patients with inflammatory bowel disease
Nam, K., Park, S. H., Lee, J., Jo, S., Kim, S., Noh, S., Park, J. C., Kim, J. Y., Kim, J., Ham, N. S., et al. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14832 · Cited by 15
Genetics of Inflammatory Bowel Disease: Current Status and Future Directions
Walters, T. D., & Silverberg, M. S. (2006) · Canadian Journal of Gastroenterology · doi:10.1155/2006/326025 · Cited by 15
Pathogenic mycobacteria in water
Pedley, S., Bartram, J., Rees, G., Dufour, A. P., & Cotruvo, J. (2004) · Open Research (University of Surrey) · Cited by 16
Prevalence and Impact of Obesity in a Population-Based Cohort of Patients With Crohn’s Disease
Johnson, A. M., Harmsen, W. S., Aniwan, S., Tremaine, W. J., Raffals, L. E., Dayyeh, B. K. A., & Loftus, E. V. (2022) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001821 · Cited by 12
Self-citation
Identification of Potential Genes and Critical Pathways in Postoperative Recurrence of Crohn’s Disease by Machine Learning And WGCNA Network Analysis
Rajalingam, A., Sekar, K., & Ganjiwale, A. D. (2023) · Current Genomics · doi:10.2174/1389202924666230601122334 · Cited by 14
Drug Management in the Elderly IBD Patient
Kim, M., Katz, S., & Green, J. (2015) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-014-0039-2 · Cited by 15
The Clinical Features of Inflammatory Bowel Disease in Patients with Obesity
Kim, S. K., Lee, H., Kim, B., Park, J. H., Hwang, S. W., Yang, D., Ye, B. D., Byeon, J., Myung, S., Yang, S., et al. (2021) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/2021/9981482 · Cited by 14
The Incidence, Prevalence, and Survival of Gastroparesis in Olmsted County, Minnesota, 1996-2006 (Gastroenterology 2009;136:1225-1233)
Jung, H. (2010) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2010.16.1.99 · Cited by 14

Authors: Loftus, E. V., Silverstein, M. D., Sandborn, W. J., Tremaine, W. J., Harmsen, W. S., & Zinsmeister, A. R.
Affiliations: Mayo Clinic (US)
ORCID: Loftus, Edward V.
Sandborn, William J.
Harmsen, W.Scott
Venue: Gastroenterology
Publisher: Elsevier BV
Published: 1998-06
Volume: 114
Issue: 6
Pages: 1161-1168
ISSN: 0016-5085 (ISSN-L)
DOI: 10.1016/s0016-5085(98)70421-4
OpenAlex: W2171373302
Cited by: 623
References: 35
Citations by year: 2026: 1 · 2025: 8 · 2024: 5 · 2023: 12 · 2022: 13 · 2021: 21 · 2020: 16 · 2019: 17 · 2018: 16 · 2017: 30 · 2016: 26 · 2015: 21 · 2014: 21 · 2013: 33 · 2012: 31
FWCI: 9.55
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Gastroenterology (publishedVersion)
PubMed (publishedVersion)
Funders: Mayo Foundation for Medical Education and Research
American Gastroenterological Association
National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR030582, AR30582)
Topics: Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
Keywords: Crohn's disease, incidence, prevalence, survival, temporal trends, Olmsted County, Minnesota, population-based epidemiology, incidence rates
MeSH terms: Adolescent, Adult, Aged, Child, Child, Preschool, Crohn Disease, Female, Humans, Male, Middle Aged, Minnesota, Regression Analysis, Cohort Studies, Incidence, Prevalence, Proportional Hazards Models, Survival Analysis, Age Distribution, Sex Distribution

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Crohn's disease in Olmsted County, Minnesota, 1940–1993: Incidence, prevalence, and survival

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks