Cited by 623Inflammatory Bowel DiseaseOcular Diseases and Behçet’s SyndromeColorectal Cancer Screening and Detection

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Crohn's disease in Olmsted County, Minnesota, 1940–1993: Incidence, prevalence, and survival

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Loftus, Edward V., Silverstein, Marc D., Sandborn, William J., Tremaine, William J., Harmsen, W.Scott, Zinsmeister, Alan R.·1998·Gastroenterology

DOI 10.1016/s0016-5085(98)70421-4

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Abstract

Background & aims Many centers worldwide have reported an increased incidence of Crohn's disease, but population-based data in North America are sparse. We studied the incidence and prevalence of Crohn's disease in Olmsted County, Minnesota, and examined temporal trends in incidence and survival.Methods Residents diagnosed with Crohn's disease between 1970 and 1993 were incidence cases, and residents with Crohn's disease who were alive on January 1, 1991, were prevalence cases. Cases from previous studies were reconfirmed. Rates were adjusted using 1990 U.S. Census figures for whites. Incidence trends were evaluated with a Poisson regression model. Survival from diagnosis was compared with that expected for U.S. north-central whites.Results Between 1940 and 1993, 225 incidence cases were identified, for an adjusted incidence rate of 5.8 per 100,000 person-years. On January 1, 1991, there were 145 residents with Crohn's disease, an adjusted prevalence rate of 133 per 100,000, 46% higher than that seen in 1980. Incidence rates before 1964 were significantly lower than those of 1989-1993. Observed survival was less than expected (P = 0.007).Conclusions The incidence of Crohn's disease has stabilized since the 1970s at a rate higher than that seen previously. Prevalence has increased by 46% since 1980. Overall survival is slightly decreased.

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History of the Rochester Epidemiology Project
Melton, L. J. (1996) · Mayo Clinic Proceedings · doi:10.4065/71.3.266 · Cited by 1,443
Inflammatory Bowel Disease
Podolsky, D. K. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109263251306 · Cited by 1,226
Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD).
Shivananda, S., Lennard‐Jones, J. E., Logan, R. F., Fear, N. T., Price, A. B., Carpenter, L., & BLANKENSTEIN, M. V. (1996) · Gut · doi:10.1136/gut.39.5.690 · Cited by 1,024
The Patient Record in Epidemiology
Kurland, L. T., & Molgaard, C. A. (1981) · Scientific American · doi:10.1038/scientificamerican1081-54 · Cited by 780
Increased risk of large-bowel cancer in Crohn's disease with colonic involvement
Ekbom, A., Adami, H., Helmick, C. G., & Zack, M. M. (1990) · The Lancet · doi:10.1016/0140-6736(90)91889-i · Cited by 698
The epidemiology of inflammatory bowel disease: A large, population-based study in Sweden
Ekbom, A., Helmick, C. G., Zack, M. M., & Adami, H. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90202-v · Cited by 436
Intestinal cancer risk and mortality in patients with Crohn's disease
Munkholm, P., Langholz, E., Davidsen, M., & Binder, V. (1993) · Gastroenterology · doi:10.1016/0016-5085(93)91068-s · Cited by 379
Incidence and Prevalence of Crohn's Disease in the County of Copenhagen, 1962-87: A Sixfold Increase in Incidence
Munkholm, P. S., Langholz, E., Nielsen, O. H., Kreiner, S., & Binder, V. (1992) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529209000127 · Cited by 300
Digestive diseases in the United States: Epidemiology and impact
Locke, G. R. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90479-4 · Cited by 298
Geographic variation of inflammatory bowel disease within the United States
Sonnenberg, A., McCarty, D. J., & Jacobsen, S. J. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90594-b · Cited by 283

Show all 35 references

Research works printed but not linked: 2

Bernstein, 1997, The high prevalence of Crohn's disease in a central Canadian province: a population-based epidemiologic study (abstr), Gastroenterology, 112, A932
Loftus, 1997, Incidence and prevalence of ulcerative colitis in Olmsted County, Minnesota, 1970–1993 (abstr), Gastroenterology, 112, A1027

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Authors: Loftus, E. V., Silverstein, M. D., Sandborn, W. J., Tremaine, W. J., Harmsen, W. S., & Zinsmeister, A. R.
Affiliations: Mayo Clinic (US)
ORCID: Loftus, Edward V.
Sandborn, William J.
Harmsen, W.Scott
Venue: Gastroenterology
Publisher: Elsevier BV
Published: 1998-06
Volume: 114
Issue: 6
Pages: 1161-1168
ISSN: 0016-5085 (ISSN-L)
DOI: 10.1016/s0016-5085(98)70421-4
OpenAlex: W2171373302
Cited by: 623
References: 35
Citations by year: 2026: 1 · 2025: 8 · 2024: 5 · 2023: 12 · 2022: 13 · 2021: 21 · 2020: 16 · 2019: 17 · 2018: 16 · 2017: 30 · 2016: 26 · 2015: 21 · 2014: 21 · 2013: 33 · 2012: 31
FWCI: 9.55
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Gastroenterology (publishedVersion)
PubMed (publishedVersion)
Funders: Mayo Foundation for Medical Education and Research
American Gastroenterological Association
National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR030582, AR30582)
Topics: Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
Keywords: Crohn's disease, incidence, prevalence, survival, temporal trends, Olmsted County, Minnesota, population-based epidemiology, incidence rates
MeSH terms: Adolescent, Adult, Aged, Child, Child, Preschool, Crohn Disease, Female, Humans, Male, Middle Aged, Minnesota, Regression Analysis, Cohort Studies, Incidence, Prevalence, Proportional Hazards Models, Survival Analysis, Age Distribution, Sex Distribution

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Crohn's disease in Olmsted County, Minnesota, 1940–1993: Incidence, prevalence, and survival

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