Cigarette smoking and open tibial fractures
Abstract
Complication rates were compared in 140 smoking and 133 non-smoking patients with open tibial fractures. Both the groups were evenly matched demographically and in terms of primary fracture treatment. Flap failure complicated 7 (20%) patients in the smoking group and 4 (14%) in the non-smoking group. The mean time to union was 32 weeks for smokers and 28 weeks for non-smokers (P<0.05). Bone grafting to stimulate union was required in 36 (26%) smoking patients compared with 24 (18%) non-smoking patients. In patients treated by intramedullary nailing exchange, nailing to achieve union was carried out in 24 (38%) smoking cases compared with 13 (26%) of non-smoking cases. Smoking is associated with an increased risk of complications in patients with open tibial fractures. There is an increased rate of flap failure, delayed union and non-union. We recommend patients with open tibial fractures should be advised to stop smoking to minimise these complications.
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Patients with open and high-grade open fractures needed much more time to heal if they were smokers (32.3 weeks for smokers versus 27.8 weeks for non-smokers).
“For example, it was observed that patients with open and high-grade open fractures needed much more time to heal if they were smokers (32.3 weeks for smokers versus 27.8 weeks for non-smokers) [55].”
From Skeletal System Biology and Smoke Damage: From Basic Science to Medical Clinic (2021) · cites this paper as [55]
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- Authors
- Adams, C. I., Keating, J. F., & Court-Brown, C. M.
- Affiliations
- Edinburgh Royal Infirmary (GB)
- Corresponding author
- Keating, J.F
- ORCID
- Keating, J.F
- Venue
- Injury
- Publisher
- Elsevier BV
- Published
- 2001-01
- Volume
- 32
- Issue
- 1
- Pages
- 61-65
- ISSN
- 0020-1383 (ISSN-L)
- OpenAlex
- W2017113692
- Cited by
- 231
- References
- 24
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 5 · 2023: 5 · 2022: 8 · 2021: 14 · 2020: 14 · 2019: 13 · 2018: 10 · 2017: 11 · 2016: 12 · 2015: 9 · 2014: 15 · 2013: 12 · 2012: 14
- FWCI
- 3.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Injury (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Bone fractures and treatments
- Health Sciences › Medicine › Surgery › Reconstructive Surgery and Microvascular Techniques
- Health Sciences › Medicine › Surgery › Muscle and Compartmental Disorders
- Keywords
- cigarette smoking, open tibial fractures, flap failure, delayed union, nonunion, bone grafting, intramedullary nailing, fracture complications, smoking cessation
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Fracture Fixation, Intramedullary, Fractures, Open, Fractures, Ununited, Humans, Male, Middle Aged, Smoking, Surgical Flaps, Tibial Fractures, Wound Infection, Fracture Healing, Treatment Failure
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