The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6).
Open accessAbstract
A new fucoganglioside, 6B, which accumulates in human colonic adenocarcinoma but is absent in normal colonic mucosa, was isolated from a monosialoganglioside fraction of colonic adenocarcinomas. The structure of this ganglioside was identified as shown below by methylation analysis, direct probe mass spectrometry, and enzymatic degradation followed by examination of the degradation products with specific monoclonal antibodies. (formula; see text) The hybridoma (FH6) secreting a monoclonal IgM antibody directed to this glycolipid was selected by reactivity of the antibody with this ganglioside and lack of reactivity with other glycolipids having a closely related structure, such as sialosyllactoneotetraosylceramide (IV3NeuAcnLc4), sialosyllactofucopentaosy(III)ceramide (IV3NeuAcIII3FucnLc4), sialosyllactofucopentaosy(II)ceramide (sialosyl-Lea glycolipid; IV3NeuAcIII4FucLc4), and 6C fucoganglioside (sialosyl 2 leads to 6 fucoganglioside; VI6NeuAcIII3FucnLc6). The antibody was highly reactive with a large variety of human cancer cells, but was less reactive or did not react with a variety of normal cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Continuous cultures of fused cells secreting antibody of predefined specificity
KÖHLER, G., & MILSTEIN, C. (1975) · Nature · doi:10.1038/256495a0 · Cited by 17,229
Magnani, J. L., Nilsson, B., Brockhaus, M., Zopf, D., Steplewski, Z., Koprowski, H., & Ginsburg, V (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)45389-1 · Cited by 881
Determination of aminosugar linkages in glycolipids by methylation
Stellner, K., Saito, H., & Hakomori, S.-I. (1973) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(73)90138-0 · Cited by 830
Self-citation[10] Gangliosides: Structure, isolation, and analysis
Ledeen, R. W., & Yu, R. K. (1982) · Methods in Enzymology · doi:10.1016/0076-6879(82)83012-7 · Cited by 701
Pukel, C. S., Lloyd, K. O., Travassos, L. R., Dippold, W. G., Oettgen, H. F., & Old, L. J. (1982) · The Journal of experimental medicine · doi:10.1084/jem.155.4.1133 · Cited by 576
Glycosphingolipids as Tumor-Associated and Differentiation Markers 56
(1983) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/71.2.231 · Cited by 569
A Sphingolipid Having a Novel Type of Ceramide and Lacto-N-Fucopentaose III
Yang, H.-J., & Hakomori, S.-I. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76958-0 · Cited by 484
Self-citationMagnani, J. L., Smith, D. F., & Ginsburg, V. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90667-3 · Cited by 474
HAKOMORI, S. (1975) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(75)90008-6 · Cited by 383
Self-citationKannagi, R., Nudelman, E., Levery, S. B., & Hakomori, S. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33363-5 · Cited by 353
Self-citation
Cited by
ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le x
Phillips, M. L., Nudelman, E., Gaeta, F. C. A., Perez, M., Singhal, A. K., Hakomori, S.-I., & Paulson, J. C. (1990) · Science · doi:10.1126/science.1701274 · Cited by 1,306
Self-citationRecognition by Elam-1 of the Sialyl-Le x Determinant on Myeloid and Tumor Cells
Walz, G., Aruffo, A., Kolanus, W., Bevilacqua, M., & Seed, B. (1990) · Science · doi:10.1126/science.1701275 · Cited by 962
The repertoire of glycan determinants in the human glycome
Cummings, R. D. (2009) · Molecular BioSystems · doi:10.1039/b907931a · Cited by 487
Hakomori, S.-I. (2001) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4615-1267-7_24 · Cited by 448
Self-citationIoffe, E., & Stanley, P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.728 · Cited by 400
Metadata
- Authors
- Fukushi, Y., Nudelman, E., Levery, S. B., Hakomori, S., & Rauvala, H.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1984-08
- Volume
- 259
- Issue
- 16
- Pages
- 10511-10517
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1549953248
- Cited by
- 280
- References
- 23
- FWCI
- 4.88
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6). https://app.cochat.ai/papers/10.1016/s0021-9258(18)90993-2
- The paper
- Fukushi, Y., Nudelman, E., Levery, S. B., Hakomori, S., & Rauvala, H. (1984). Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6). Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)90993-2
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
