Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption

New Perspectives in Cell Adhesion: RGD and Integrins

Ruoslahti, E. I., & Pierschbacher, M. D. (1987) · Science · doi:10.1126/science.2821619 · Cited by 4,875

Integrins: A family of cell surface receptors

Hynes, R. O. (1987) · Cell · doi:10.1016/0092-8674(87)90233-9 · Cited by 4,258

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

Hemler, M. E. (1990) · Annual Review of Immunology · doi:10.1146/annurev.iy.08.040190.002053 · Cited by 1,561

Integrins.

Ruoslahti, E. I. (1991) · Journal of Clinical Investigation · doi:10.1172/jci114957 · Cited by 1,391

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

Oldberg, Å., Franzén, A., & Heinegård, D. K. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.23.8819 · Cited by 1,081

Bone and Mineral Research

(1990) · Elsevier eBooks · doi:10.1016/c2009-0-34738-8 · Cited by 1,073

Osteopontin--a possible anchor of osteoclasts to bone.

Reinholt, F. P., Hultenby, K. R., Oldberg, Å., & Heinegård, D. K. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4473 · Cited by 831

The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

Lawler, J., & Hynes, R. O. (1986) · The Journal of Cell Biology · doi:10.1083/jcb.103.5.1635 · Cited by 580

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

Cheresh, D. A. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.18.6471 · Cited by 569

Structure and biology of cartilage and bone matrix noncollagenous macromolecules

Heinegård, D. K., & Oldberg, Å. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.9.2663581 · Cited by 567

Role of Vitronectin Receptor-Type Integrins and Osteopontin in Ischemia-Induced Retinal Neovascularization

Takagi, H. (2002) · Japanese Journal of Ophthalmology · doi:10.1016/s0021-5155(02)00482-3 · Cited by 30

Autocrine and paracrine nitric oxide regulate attachment of human osteoclasts

Yaroslavskiy, B. B., Li, Y., Ferguson, D. J. P., Kalla, S. E., Oakley, J. I., & Blair, H. C. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20009 · Cited by 30

Novel bioactivity of phosvitin in connective tissue and bone organogenesis revealed by live calvarial bone organ culture models

Liu, J., Czernick, D., Lin, S.-C., Alasmari, A. A., Dibart, S., & Salih, E. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.06.005 · Cited by 29

Both Full-Length and Protease-Cleaved Products of Osteopontin Are Elevated in Infectious Diseases

Hattori, T., Iwasaki, H., Bai, G., Yasutan, H. C., Shete, A., Telan, E. F. O., Takahashi, A., Ashino, Y., & Matsuba, T. (2021) · Biomedicines · doi:10.3390/biomedicines9081006 · Cited by 29

Bone Biology and Fracture Healing

Lopez, M. J., & Markel, M. D. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0867-7.00074-0 · Cited by 29

Integrins and Other Cell Surface Attachment Molecules of Bone Cells

Horton, M. A., Nesbitt, S. A., Bennett, J. H., & Stenbeck, G. (2002) · Elsevier eBooks · doi:10.1016/b978-012098652-1.50119-0 · Cited by 29

Oligodeoxynucleotide Targeted to the αv Gene Inhibits αv Integrin Synthesis, Impairs Osteoclast Function, and Activates Intracellular Signals to Apoptosis

Villanova, I., Townsend, P. A., Uhlmann, E., Knolle, J., Peyman, A., Amling, M., Baron, R., Horton, M. A., & Teti, A. M. (1999) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1999.14.11.1867 · Cited by 29

Relative abundance of different cadherins defines differentiation of mesenchymal precursors into osteogenic, myogenic, or adipogenic pathways

Shin, C. S., Lecanda, F., Sheikh, S., Weitzmann, L., Cheng, S., & Civitelli, R. (2000) · Journal of Cellular Biochemistry · doi:10.1002/1097-4644(20000915)78:4 · Cited by 104

Complete Topographical Distribution of Both the in Vivo and in Vitro Phosphorylation Sites of Bone Sialoprotein and Their Biological Implications

Salih, E., & Flückiger, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310299200 · Cited by 28

Measurement of Biochemical Markers of Bone Resorption

KRAENZLIN, M. E., & Seibel, M. J. (2006) · Elsevier eBooks · doi:10.1016/b9-78-012088-5/62650-0340 · Cited by 28

Ganglion cells of the rat retina show osteopontin-like immunoreactivity

Ju, W., Keun-young Kim, A., Cha, J., Kim, I., Lee, M., Oh, S.-J., Chung, J.-W., & Chun, M. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02140-x · Cited by 28

Correlation between the expression of integrins in prostate cancer and clinical outcome in 1284 patients

Heß, K., Böger, C., Behrens, H., & Röcken, C. (2014) · Annals of Diagnostic Pathology · doi:10.1016/j.anndiagpath.2014.09.001 · Cited by 27

A comparative study on BMP-induced osteoclastogenesis and osteoblastogenesis in primary cultures of adult rat bone marrow cells

Paul, S., Lee, J. C., & Yeh, L. C. (2009) · Growth Factors · doi:10.1080/08977190802707324 · Cited by 27

A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and αvβ3 integrin for osteoporosis therapy

Zur, Y., Rosenfeld, L., Keshelman, C. A., Dalal, N., Ram, G. G., Orenbuch, A., Einav, Y., Levaot, N., & Papo, N. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2002979 · Cited by 27

High Expression of Osteopontin and CD44v6 in Odontogenic Keratocysts

Wang, Y., & Liu, B.-Y. (2009) · Journal of the Formosan Medical Association · doi:10.1016/s0929-6646(09)60068-1 · Cited by 27

“Insularin, a disintegrin from Bothrops insularis venom: Inhibition of platelet aggregation and endothelial cell adhesion by the native and recombinant GST-insularin proteins”

Della-Casa, M. S., Junqueira-de-Azevedo, I. L. M., Butera, D., Clissa, P. B., Lopes, D. S., Serrano, S. M. T., Pimenta, D. C., Magalhães, G. S., Ho, P. L., & Moura-da-Silva, A. M. (2010) · Toxicon · doi:10.1016/j.toxicon.2010.10.013 · Cited by 27

Characterization of the chicken osteopontin-encoding gene

Rafidi, K., Simkina, I., Johnson, E., Moore, M. A., & Gerstenfeld, L. C. (1994) · Gene · doi:10.1016/0378-1119(94)90540-1 · Cited by 27

Physiology of Bone Remodeling

Chenu, C., & Delmas, P. D. (1998) · Advances in organ biology · doi:10.1016/s1569-2590(08)60107-x · Cited by 26

Treatment of bone metastasis induced by MDA-MB-231 breast cancer cells with an antibody against bone sialoprotein

Bäuerle, T., Peterschmitt, J., Hilbig, H., Kiessling, F. M., Armbruster, F. P., & Berger, M. R. (2006) · International Journal of Oncology · doi:10.3892/ijo.28.3.573 · Cited by 26

Serum bone sialoprotein: a marker of bone resorption in postmenopausal osteoporosis

Shaarawy, M. (2001) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/003655101753218274 · Cited by 26

O-phospho-l-serine: a modulator of bone healing in calcium-phosphate cements

Mai, R., Lux, R., Proff, P., Lauer, G., Pradel, W., Leonhardt, H., Reinstorf, A., Gelinsky, M., Jung, R., Eckelt, U., et al. (2008) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt.2008.040 · Cited by 26

O‐phospho‐L‐serine modified calcium phosphate cements – material properties, in vitro and in vivo investigations

Reinstorf, A., Hempel, U., Olgemöller, F., Domaschke, H., Schneiders, W., Mai, R., Stadlinger, B., Rösen-Wolff, A., Rammelt, S., Gelinsky, M., et al. (2006) · Materialwissenschaft und Werkstofftechnik · doi:10.1002/mawe.200600026 · Cited by 26

Interactions Between Vacuolar H+-ATPases and Microfilaments in Osteoclasts

Holliday, L. S., Bubb, M., Jiang, J. Q., Hurst, I. R., & Zuo, J. (2005) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-005-9483-y · Cited by 26

Retinoic acid induces osteoclast-like cell formation by directly acting on hemopoietic blast cells and stimulates osteopontin mRNA expression in isolated osteoclasts

Kaji, H., Sugimoto, T., Kanatani, M., Fukase, M., Kumegawa, M., & Chihara, K. (1995) · Life Sciences · doi:10.1016/0024-3205(95)00165-3 · Cited by 26

Fibulin-2 is a key mediator of the pro-neurogenic effect of TGF-beta1 on adult neural stem cells

Radice, P. D., Mathieu, P., Leal, M. C., Farías, M. I., Ferrari, C., Puntel, M., Salibe, M., Chernomoretz, A., & Pitossi, F. J. (2015) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2015.06.004 · Cited by 25

Establishment of a biomarker model for predicting bone metastasis in resected stage III non-small cell lung cancer

Zhou, Z., Chen, Z., Yang, X., Shen, L., Ai, X., Lü, S., & Luo, Q. (2012) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-31-34 · Cited by 25

1α,25-dihydroxyvitamin D3 stimulation of osteopontin expression in rat clonal dental pulp cells

Nagata, T., Yokota, M., Ohishi, K., Nishikawa, S., Shinohara, H., Wakano, Y., & Ishida, H. (1994) · Archives of Oral Biology · doi:10.1016/0003-9969(94)90007-8 · Cited by 25

Osteopontin at the Tumor/Host Interface

Senger, D. R., Brown, L. F., Perruzzi, C. A., Papadopoulos-Sergiou, A., & Water, L. V. D. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44622.x · Cited by 25

Influence of different modifications of a calcium phosphate bone cement on adhesion, proliferation, and osteogenic differentiation of human bone marrow stromal cells

Vater, C., Lode, A., Bernhardt, A., Reinstorf, A., Heinemann, C., & Gelinsky, M. (2009) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32469 · Cited by 24

Inhibition of Avian Osteoclast Bone Resorption by Monoclonal Antibody 121F: A Mechanism Involving the Osteoclast Free Radical System

Collin‐Osdoby, P., Li, L., Rothe, L., Anderson, F. L., Kirsch, D., Oursler, M. J., & Osdoby, P. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.1.67 · Cited by 24

The Regulatory Role of Matrix Proteins in Mineralization of Bone

Zhu, W., Robey, P. G., & Boskey, A. L. (2008) · Elsevier eBooks · doi:10.1016/b978-012370544-0.50011-2 · Cited by 27

Characterization of an Avian Bone Sialoprotein (BSP) cDNA: Comparisons to Mammalian BSP and Identification of Conserved Structural Domains

Yang, R., GOTOH, Y., Moore, M. A., Rafidi, K., & Gerstenfeld, L. C. (1995) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650100417 · Cited by 24

Milk osteopontin promotes intestinal development by up‐regulating the expression of integrin αvβ3 and CD44

Jiang, R., Lo, J., Prell, C., & Lönnerdal, B. L. (2023) · The FASEB Journal · doi:10.1096/fj.202300092r · Cited by 23

The differences between the localizations of MUC1, MUC5AC, MUC6 and osteopontin in quail proventriculus and gizzard may be a reflection of functional differences of stomach parts

Liman, N., Alan, E., & Bayram, G. K. (2010) · Journal of Anatomy · doi:10.1111/j.1469-7580.2010.01243.x · Cited by 23

Competition for a Unique Response Element Mediates Retinoic Acid Inhibition of Vitamin D3-stimulated Transcription

Cao, X., Teitelbaum, S. L., Zhu, H.-J., Zhang, L., Feng, X., & Ross, F. P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.34.20650 · Cited by 23

Osteopontin is a constitutive component of normal elastic fibers in human skin and aorta

Baccarani-Contri, M., Taparelli, F., & Pasquali‐Ronchetti, I. (1995) · Matrix Biology · doi:10.1016/s0945-053x(05)80004-6 · Cited by 23

Localization of Alkaline Phosphatase and Osteopontin during Matrix Mineralization in the Developing Cartilage of Coccygeal Vertebrae.

Sasaki, T., Amizuka, N., Irie, K., Ejiri, S., & Ozawa, H. (2000) · Archivum histologicum japonicum · doi:10.1679/aohc.63.271 · Cited by 23

Biochemical Markers of Bone Turnover – Basic Biochemistry and Variability

Seibel, M. J., & Meier, C. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-459-9_5 · Cited by 22

Effect of radiation on the expression of osteoclast marker genes in RAW264.7 cells

Yang, B., Zhou, H., Zhang, X., Liu, Z., Fan, F., & Sun, Y. (2012) · Molecular Medicine Reports · doi:10.3892/mmr.2012.765 · Cited by 23

Osteoblastic meningiomas: clinico-pathological and immunohistochemical features of an uncommon variant

Barresi, V., Caffo, M., Ieni, A., Alafaci, C., & Tuccari, G. (2011) · Journal of Neuro-Oncology · doi:10.1007/s11060-011-0588-3 · Cited by 22

Applications of transgenics in studies of bone sialoprotein

Zhang, J., Tu, Q., & Chen, J. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21768 · Cited by 22

Histochemical examination of osteoblastic activity in op/op mice with or without injection of recombinant M-CSF

Nishino, I., Amizuka, N., & Ozawa, H. (2001) · Journal of Bone and Mineral Metabolism · doi:10.1007/s007740170010 · Cited by 22

Approach to discovering novel therapeutic agents for osteoporosis based on integrin receptor blockade

Chorev, M., Dresner–Pollak, R., Eshel, Y., & Rosenblatt, M. (1995) · Biopolymers · doi:10.1002/bip.360370603 · Cited by 22

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET

Beer, A. J., Schwarzenböck, S. M., Zantl, N., Souvatzoglou, M., Maurer, T., Watzlowik, P., Kessler, H., Wester, H., Schwaiger, M., & Krause, B. J. (2016) · Oncotarget · doi:10.18632/oncotarget.8611 · Cited by 21

Anti-osteopontin monoclonal antibody prevents ovariectomy-induced osteoporosis in mice by promotion of osteoclast apoptosis

Zhang, B., Dai, J., Wang, H., Wei, H., Zhao, J., Guo, Y., & Fan, K. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.08.149 · Cited by 21

Osteoclast precursors circulate in avian blood

Alvarez, J. I., Ross, F. P., Athanasou, N. A., Blair, H. C., Greenfield, E. M., & Teitelbaum, S. L. (1992) · Calcified Tissue International · doi:10.1007/bf00296217 · Cited by 21

The role of bone sialoprotein in bone healing

Foster, B. L. (2024) · Journal of Structural Biology · doi:10.1016/j.jsb.2024.108132 · Cited by 20

Distinctive and selective route of PI3K/PKCα-PKCδ/RhoA-Rac1 signaling in osteoclastic cell migration

Kim, J., Kim, M. Y., Lee, K., & Jeong, D. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.08.042 · Cited by 20

Early and late gene expression profiles of the ovine mucosa in response to Haemonchus contortus infection employing Illumina RNA-seq technology

El-Ashram, S. A., Nasr, I. S. A., El-Kemary, M. A., Mehmood, R., Hu, M., & Suo, X. (2017) · Parasitology International · doi:10.1016/j.parint.2017.05.007 · Cited by 20

Biochemical markers of bone remodeling and bone sialoprotein in ankylosing spondylitis

Acebes, C., de la Piedra, C., Traba, M. L., Seibel, M. J., Martı́n, C. G., Armas, J., & Herrero‐Beaumont, G. (1999) · Clinica Chimica Acta · doi:10.1016/s0009-8981(99)00170-9 · Cited by 20

Biochemical Markers to Survey Bone Turnover

Woitge, H. W., & Seibel, M. J. (2001) · Rheumatic Disease Clinics of North America · doi:10.1016/s0889-857x(05)70187-3 · Cited by 20

mRNA Expression of MT1-MMP, MMP-9, Cathepsin K, and TRAP in Highly Enriched Osteoclasts Cultured on Several Matrix Proteins and Ivory Surfaces

Uemura, T., Liu, Y. K., & Kuboki, Y. (2000) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.64.1771 · Cited by 20

Expression of osteopontin by exudate macrophages in inflammatory tissues of the middle ear: a possible association with development of tympanosclerosis

Makiishi-Shimobayashi, C., Tsujimura, T., Sugihara, A., Iwasaki, T., Yamada, N., Terada, N., & Sakagami, M. (2001) · Hearing Research · doi:10.1016/s0378-5955(00)00260-4 · Cited by 20

Retinoic acid stimulates expression of the functional osteoclast integrin αvβ3: Transcriptional activation of the β3 but not the αv gene

Chiba, M., Teitelbaum, S. L., Cao, X., & Ross, F. P. (1996) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(19960915)62:4 · Cited by 20

Modulation of Bone Resorption by Phosphorylation State of Bone Sialoprotein

Curtin, P., McHugh, K. P., Zhou, H.-Y., Flückiger, R., Goldhaber, P., Oppenheim, F. G., & Salih, E. (2009) · Biochemistry · doi:10.1021/bi900066b · Cited by 19

The Integrin αvβ5 Is Expressed on Avian Osteoclast Precursors and Regulated by Retinoic Acid

Sago, K., Teitelbaum, S. L., Venstrom, K., Reichardt, L. F., & Ross, F. P. (1999) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1999.14.1.32 · Cited by 19

Discrete region of the insulin receptor carboxyl terminus plays key role in insulin action

Bernier, M., Kole, H. K., Montrose‐Rafizadeh, C., & Kole, S. (2000) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(20000701)78:1 · Cited by 1

Characterization of the Bone Sialoprotein (BSP) Gene Promoter

Sodek, J., Li, J. J., Kim, R. H., Ogata, Y., & Yamauchp, M. (1996) · Connective Tissue Research · doi:10.3109/03008209609029171 · Cited by 19

Cloning of the Murine β5 Integrin Subunit Promoter

Feng, X., Teitelbaum, S. L., Quiroz, M. E., Towler, D. A., & Ross, F. P. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.3.1366 · Cited by 19

RAN GTPase and Osteopontin in Pancreatic Cancer

Saxena, S. (2013) · Pancreatic Disorders and Therapy · doi:10.4172/2165-7092.1000113 · Cited by 18

Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study

Cheng, Y., Li, Y., Scherer, N., Grundner-Culemann, F., Lehtimäki, T. J., Mishra, B. H., Raitakari, O. T., Nauck, M. A., Eckardt, K., Sekula, P., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010139 · Cited by 19

Localization of osteopontin at calcification sites of cholesteatoma: possible role as a regulator of deposition of calcium phosphate in the middle ear

Makiishi-Shimobayashi, C., Tsujimura, T., Iwasaki, T., Kakihana, M., Shimano, K., Terada, N., & Sakagami, M. (2004) · Auris Nasus Larynx · doi:10.1016/j.anl.2003.11.010 · Cited by 18

Osteoporosis in the rheumatic disease patient

Lane, N. E., & Rehman, Q. (2002) · Lupus · doi:10.1191/0961203302lu261oa · Cited by 17

Tissue specific and vitamin D responsive gene expression in bone

White, C., Gardiner, E. M., & Eisman, J. A. (1998) · Molecular Biology Reports · doi:10.1023/a:1006820710966 · Cited by 18

Paget's disease is associated with changes in the immunohistochemical distribution of noncollagenous matrix proteins in bone

Ingram, R. T., Collazo–Clavell, M. L., Tiegs, R. D., & Fitzpatrick, L. A. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.5.1810 · Cited by 18

Localization of osteopontin in resorption lacunae formed by osteoclast-like cells: a study by a novel monoclonal antibody which recognizes rat osteopontin

Maeda, H., AKAMINE, A., Kukita, T., Iijima, T., & Kukita, A. (1994) · Histochemistry and Cell Biology · doi:10.1007/bf00269160 · Cited by 18

cAMP and fibroblast growth factor 2 regulate bone sialoprotein gene expression in human prostate cancer cells

Li, Z., Sasaki, Y., Mezawa, M., Wang, S., Li, X., Yang, L., Wang, Z., Zhou, L., Araki, S., Matsumura, H., et al. (2010) · Gene · doi:10.1016/j.gene.2010.09.009 · Cited by 17

Topographical distribution of phosphorylation sites of phosvitins by mass spectrometry

Czernick, D., Liu, J., Dibart, S., & Salih, E. (2013) · Journal of Proteomics · doi:10.1016/j.jprot.2013.02.016 · Cited by 17

Expression of osteopontin and its receptors in ameloblastomas

Wang, Y., & Liu, B.-Y. (2008) · Oral Oncology · doi:10.1016/j.oraloncology.2008.07.015 · Cited by 17

Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51

Sims, M. A., Field, S. D., Barnes, M. R., Shaikh, N., Ellington, K., Murphy, K. E., Spurr, N. K., & Campbell, D. A. (2000) · Cytogenetic and Genome Research · doi:10.1159/000015631 · Cited by 17

Effects of bone sialoprotein on pancreatic cancer cell growth, invasion and metastasis

Kayed, H., Kleeff, J. H., Keleg, S., Felix, K., Giese, T., Berger, M. R., Büchler, M. W., & Friess, H. (2006) · Cancer Letters · doi:10.1016/j.canlet.2006.01.002 · Cited by 17

Evidence for Phosphoprotein Microspheres in Bone

Carter, D. H., Scully, A. J., Davies, R. M., & Aaron, J. E. (1998) · The Histochemical Journal · doi:10.1023/a:1003490506980 · Cited by 17

Expression of osteopontin in Meckel's cartilage cells during phenotypic transdifferentiation in vitro, as detected by in situ hybridization and immunocytochemical analysis

Ishizeki, K., Nomura, S., Takigawa, M., Shioji, H., & Nawa, T. (1998) · Histochemistry and Cell Biology · doi:10.1007/s004180050307 · Cited by 17

Regulation of Avian Osteopontin Pre‐and Posttranscriptional Expression in Skeletal Tissuesa

Gerstenfeld, L. C., Uporova, T. M., Ashkar, S., Salih, E., GOTOH, Y., McKee, M. D., Nanci, A., & Glimcher, M. J. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44621.x · Cited by 17

Osteopontin antisense deoxyoligonucleotides inhibit bone resorption by mouse osteoclasts in vitro

Tani‐lshii, N., Tsunoda, A., & Umemoto, T. (1997) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1997.tb00563.x · Cited by 17

Cloning and sequence analysis of bovine bone sialoprotein cDNA: Conservation of acidic domains, tyrosine sulfation consensus repeats, and RGD cell attachment domain

Chenu, C., Ibaraki, K., Robey, P. G., Delmas, P. D., & Young, M. F. (1994) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650090318 · Cited by 17

Interrelationship between signal transduction pathways and 1,25(OH)2D3in UMR106 osteoblastic cells

Yang, W., Hyllner, S. J., & Christakos, S. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.281.1.e162 · Cited by 17

Role of carbonic anhydrase II in ectopic calcification

Rajachar, R. M., Tung, E. L., Truong, A. Q., Look, A. E., & Giachelli, C. M. (2008) · Cardiovascular Pathology · doi:10.1016/j.carpath.2007.11.004 · Cited by 16

Importance of integrin receptors in the field of pharmaceutical & medical science

Goswami, S. (2013) · Advances in Biological Chemistry · doi:10.4236/abc.2013.32028 · Cited by 16

Subcellular Elevation of Cytosolic Free Calcium Is Required for Osteoclast Migration

Wheal, B. D., Beach, R. J., Tanabe, N., Dixon, S. J., & Sims, S. M. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2068 · Cited by 16

Osteopetrosis with micro-lacunar resorption because of defective integrin organization

Blair, H. C., Yaroslavskiy, B. B., Robinson, L. J., Mapara, M. Y., Pangrazio, A., Guo, L., Chen, K., Vezzoni, P., Tolar, J., & Orchard, P. J. (2009) · Laboratory Investigation · doi:10.1038/labinvest.2009.58 · Cited by 16

Effect of bone sialoprotein on proliferation and osteodifferentiation of human bone marrow-derived mesenchymal stem cells in vitro

Xia, B., Wang, J., Guo, L., & Jiang, Z. (2011) · Biologicals · doi:10.1016/j.biologicals.2011.04.004 · Cited by 16

Osteoclast Biology

Ross, F. P., & Teitelbaum, S. L. (2001) · Elsevier eBooks · doi:10.1016/b978-012470862-4/50004-0 · Cited by 16

Engagement of the Osteoclast Integrin αvβ3 by Osteopontin Stimulates Phosphatidylinositol 3‐Hydroxyl Kinase Activityab

Hruska, K. A., ROLNICK, F., Huskey, M., Alvarez, U., & Cheresh, D. A. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44627.x · Cited by 16

Cilengitide inhibits osteoclast adhesion through blocking the αvβ3-mediated FAK/Src signaling pathway

Guo, D., Chen, Z.-H., Fu, Y.-F., Li, Y., Chen, M.-N., Wu, J., Yuan, Z., Ye, J., Li, X., & Yuan, F. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e17841 · Cited by 15

Markers of Bone and Cartilage Turnover

Woitge, H. W., & Seibel, M. J. (2017) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0043-106438 · Cited by 15

Imaging αvβ3 integrin expression in skeletal metastases with 99mTc-maraciclatide single-photon emission computed tomography: detection and therapy response assessment

Cook, G., Azad, G. K., Taylor, B. P., Lee, E., Morrison, M. S., Hughes, S., Morris, S. L., Rudman, S. M., Chowdhury, S., & Goh, V. (2018) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-017-3926-7 · Cited by 15

Protein Kinases of Cultured Chicken Osteoblasts That Phosphorylate Extracellular Bone Proteins

Salih, E., Ashkar, S., Zhou, H.-Y., Gerstenfeld, L. C., & Glimcher, M. J. (1996) · Connective Tissue Research · doi:10.3109/03008209609029193 · Cited by 15

Non-peptide α v β 3 antagonists: Identification of potent, chain-shortened RGD mimetics that incorporate a central pyrrolidinone constraint

Perkins, J. J., Duong, L. T., Fernández‐Metzler, C., Hartman, G. D., Kimmel, D. B., Leu, C., Lynch, J. J., Prueksaritanont, T., Rodan, G. A., Rodan, S. B., et al. (2003) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2003.09.055 · Cited by 15

Immunodetection of Osteopontin at Sites of Resorption in the Pulp of Rat Molars

Shimazu, Y., Nanci, A., & Aoba, T. (2002) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215540205000705 · Cited by 15

Osteopontin in the Cerebrospinal Fluid of Patients with Severe Aneurysmal Subarachnoid Hemorrhage

Abate, M., Moretto, L., Licari, I., Esposito, T., Capuano, L., Olivieri, C., Benech, A., Brucoli, M., Avanzi, G., Cammarota, G., et al. (2019) · Cells · doi:10.3390/cells8070695 · Cited by 15

Molecular Basis of Recognition of Human Osteopontin by 23C3, a Potential Therapeutic Antibody for Treatment of Rheumatoid Arthritis

Du, J., Hou, S., Zhong, C., Lai, Z., Yang, H., Dai, J., Zhang, D., Wang, H., Guo, Y., & Ding, J. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.07.075 · Cited by 14

Correlation between osteopontin and caveolin-1 in the pathogenesis and progression of osteoarthritis

MIN, T., Sheng, L., Chao, C., Tian, J., GUANG, G. S., & HUA, L. G. (2015) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2015.2433 · Cited by 14

Integrins and Other Cell Surface Attachment Molecules of Bone Cells

Helfrich, M., Stenbeck, G., Nesbitt, S. A., & Horton, M. A. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-373884-4.00039-2 · Cited by 14

Recent Developments in Metabolic Bone Diseases: a Gnathic Perspective

Raubenheimer, E. J., Noffke, C. E. E., & Hendrik, H. D. (2014) · Head and Neck Pathology · doi:10.1007/s12105-014-0580-2 · Cited by 13

Osteopontin Distribution in the Canine Skeleton during Growth and Structural Maturation

Schnapper, A., & Meyer, W. (2004) · Cells Tissues Organs · doi:10.1159/000082246 · Cited by 13

Systematic Analysis of Actively Transcribed Core Matrisome Genes Across Tissues and Cell Phenotypes

Tellman, T. V., Dede, M., Aggarwal, V. A., Salmon, D., Naba, A., & Farach‐Carson, M. C. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.06.003 · Cited by 14

Osteoclast Responses to Lipopolysaccharide, Parathyroid Hormone and Bisphosphonates in Neonatal Murine Calvaria Analyzed by Laser Scanning Confocal Microscopy

Suzuki, K., Takeyama, S., Kikuchi, T., Yamada, S., Sodek, J., & Shinoda, H. (2005) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.5a6630.2005 · Cited by 13

Interaction of Osteopontin with Osteoclast Integrinsa

Horton, M. A., Nesbit, M. A., & Helfrich, M. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44630.x · Cited by 53

Peptidomimetic antagonists of alphavbeta3 inhibit bone resorption by inhibiting osteoclast bone resorptive activity, not osteoclast adhesion to bone

Carron, C. P., Meyer, D. M., Engleman, V. W., RICO, J. G., Ruminski, P. G., Ornberg, R., Westlin, W., & Nickols, G. A. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.1650587 · Cited by 52

β1 integrins and osteoclast function: Involvement in collagen recognition and bone resorption

Helfrich, M. H., Nesbitt, S. A., Lakkakorpi, P. T., Barnes, M. J., Bodary, S. C., Shankar, G., Mason, W. T., Mendrick, D. L., Väänänen, H. K., & Horton, M. A. (1996) · Bone · doi:10.1016/s8756-3282(96)00223-2 · Cited by 139

Involvement of αvβ3 integrins in osteoclast function

Nakamura, I., Duong, L. T., Rodan, S. B., & Rodan, G. A. (2007) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-007-0773-9 · Cited by 224

Integrin function in osteoclasts

Rodan, S. B., & Rodan, G. A. (1997) · Journal of Endocrinology · doi:10.1677/joe.0.154s047 · Cited by 111