The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins
Open accessAbstract
Effects of aluminum, magnesium, and fluoride (AMF) on members of both the trimeric G protein and smaller (20-25 kDa) monomeric GTP-binding protein families were examined. The dissociation of GDP from G proteins was blocked by AMF but was unchanged with the addition of AMF to any of six of the monomeric GTP-binding proteins. Biochemical activities and properties of one of the smaller GTP-binding proteins, ADP-ribosylation factor, were also found to be unaffected by AMF. It is concluded that the ability of AMF to activate the trimeric G proteins is not shared by the smaller GTP-binding proteins and thus should prove to be a useful discriminator between cellular activities regulated by these two families of regulatory proteins.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The GTPase superfamily: a conserved switch for diverse cell functions
Bourne, H. R., Sanders, D. A., & McCormick, F. (1990) · Nature · doi:10.1038/348125a0 · Cited by 2,333
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.
Sternweis, P. C., & Robishaw, J. D. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)89817-9 · Cited by 1,301
Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G q
Smrcka, A. V., Hepler, J. R., Brown, K. O., & Sternweis, P. C. (1991) · Science · doi:10.1126/science.1846707 · Cited by 894
The Cellular Functions of Small GTP-Binding Proteins
Hall, A. (1990) · Science · doi:10.1126/science.2116664 · Cited by 867
FORMATION OF A CYCLIC ADENINE RIBONUCLEOTIDE BY TISSUE PARTICLES
Rall, T. W., & Sutherland, E. W. (1958) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77422-5 · Cited by 831
Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins
Taylor, S. J., Chae, H. Z., Rhee, S. G., & Exton, J. H. (1991) · Nature · doi:10.1038/350516a0 · Cited by 780
Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.
Sternweis, P. C., & Gilman, A. G. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.16.4888 · Cited by 624
Northup, J. K., Smigel, M. D., & Gilman, A. G. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33775-x · Cited by 547
Kahn, R. A., & Gilman, A. G. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57489-0 · Cited by 540
Self-citationFluoroaluminates activate transducin‐GDP by mimicking the γ‐phosphate of GTP in its binding site
Bigay, J., Deterre, P., Pfister, C., & Chabre, M. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)80004-1 · Cited by 417
Cited by
Signal transduction and regulation in smooth muscle
Somlyo, A. P., & Somlyo, A. V. (1994) · Nature · doi:10.1038/372231a0 · Cited by 1,902
Helms, J. B., & Rothman, J. E. (1992) · Nature · doi:10.1038/360352a0 · Cited by 746
Phospholipase D: a Downstream Effector of ARF in Granulocytes
Cockcroft, S., Thomas, G. M. H., Fensome, A., Geny, B., Cunningham, E., Gout, I., Hiles, I., Totty, N. F., Truong, O., & Hsuan, J. J. (1994) · Science · doi:10.1126/science.8290961 · Cited by 631
GTPase-activating proteins: Helping hands to complement an active site
Scheffzek, K., Ahmadian, M. R., & Wittinghofer, A. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01224-9 · Cited by 410
Receptor-activated Ca2+ influx: how many mechanisms for how many channels?
Fasolato, C., Innocenti, B., & Pozzan, T. (1994) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(94)90282-8 · Cited by 400
Metadata
- Authors
- Kahn, R. A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1991-08
- Volume
- 266
- Issue
- 24
- Pages
- 15595-15597
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1586275583
- Cited by
- 267
- References
- 23
- FWCI
- 14.21
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins. https://app.cochat.ai/papers/10.1016/s0021-9258(18)98446-2
- The paper
- Kahn, R. A. (1991). Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)98446-2
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.