The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Oxidants and antioxidants in atherogenesis: an appraisal
Open accessAbstract
Oxidized low density lipoprotein (Ox-LDL) has a plethora of components that are not present in native LDL. Their presence and quantity depends on the nature, type, and extent of oxidation. Lipids esterified to oxidized fatty acids are the major components formed during the early phase of oxidation and these show a number of proatherogenic properties in in vitro cell culture systems. Recently, evidence has been forthcoming to suggest that some of these oxidized lipids also could elicit "antioxidant;-antiatherogenic" responses from cells. Moreover, some of the cellular effects of Ox-LDL that were previously interpreted as atherogenic could also be reinterpreted to suggest an antiatherogenic cellular response. In addition to the above, the antioxidants that are carried in lipoproteins could have anomalous behavior attributable to their metabolism, ability to be internalized by arterial cells, and the presence of oxidative systems that could render them prooxidants. In conclusion, there are numerous contributing factors that need to be studied and understood before antioxidant therapy becomes an option for the treatment for cardiovascular diseases.
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Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice
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Cited by
Oxidative Stress: Harms and Benefits for Human Health
Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., Arcoraci, V., Squadrito, F., Altavilla, D., & Bitto, A. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/8416763 · Cited by 4,837
Free Radicals, Antioxidants in Disease and Health
Department of Pharmacy, L. S. P. C. H., Pham-Huy, L. A., He, H., Department of Analytical Chemistry, C. P. U., Pham-Huyc, C., & Laboratory of Toxicology, F. O. P. (2008) · International Journal of Biomedical Science · doi:10.59566/ijbs.2008.4089 · Cited by 3,058
Rudrapal, M., Khairnar, S. J., Khan, J., Dukhyil, A. B., Ansari, M. A., Alomary, M. N., Alshabrmi, F. M., Palai, S., Deb, P. K., & Devi, R. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.806470 · Cited by 1,084
Vitamin E: action, metabolism and perspectives
Herrera, E., & Barbas, C. (2001) · Journal of Physiology and Biochemistry · doi:10.1007/bf03179812 · Cited by 401
Elosua, R., Molina, L., Fito, M., Arquer, A., Sanchez-Quesada, J. L., Covas, M. I., Ordoñez-Llanos, J., & Marrugat, J. (2003) · Atherosclerosis · doi:10.1016/s0021-9150(03)00018-2 · Cited by 286
Metadata
- Authors
- Parthasarathy, S., Santanam, N., Ramachandran, S., & Meilhac, O.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1999-12
- Volume
- 40
- Issue
- 12
- Pages
- 2143-2157
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2156553719
- Cited by
- 193
- References
- 5
- FWCI
- 8.37
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Parthasarathy, S., Santanam, N., Ramachandran, S., & Meilhac, O. (1999). Oxidants and antioxidants in atherogenesis: an appraisal. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)32089-7
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
