The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
The discovery and development of HMG-CoA reductase inhibitors.
Open accessAbstract
During the 1950s and 1960s, many cholesterol-lowering agents were reported and introduced into clinical use, in-
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“Nonetheless, TGs have been demonstrated to be correlated with acute pancreatitis655).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [655]
Citations
Cites
Regulation of the mevalonate pathway
Goldstein, J. L., & Brown, M. S. (1990) · Nature · doi:10.1038/343425a0 · Cited by 5,394
Brown, G., Albers, J. J., Fisher, L. D., Schaefer, S. M., Lin, J.-T., Kaplan, C., Zhao, X.-Q., Bisson, B. D., Fitzpatrick, V. F., & Dodge, H. T. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011083231901 · Cited by 2,159
The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis
Goldstein, L. J., & Brown, S. M. (1977) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.46.070177.004341 · Cited by 1,906
All ras proteins are polyisoprenylated but only some are palmitoylated
Hancock, J. F., Magee, A. I., Childs, J. E., & Marshall, C. J. (1989) · Cell · doi:10.1016/0092-8674(89)90054-8 · Cited by 1,775
Alberts, A. W., Chen, J., Kuron, G. W., Hunt, V. M., Huff, J. W., Hoffman, C., Rothrock, J. W., López, M., Joshua, H., Harris, E., et al. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.7.3957 · Cited by 1,630
Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease.
(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-93-5-786_2 · Cited by 1,426
ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.
Endo, A., KURODA, M., & Tsujita, Y. (1976) · The Journal of Antibiotics · doi:10.7164/antibiotics.29.1346 · Cited by 954
Self-citationEndo, A., Kuroda, M., & Tanzawa, K. (1976) · FEBS Letters · doi:10.1016/0014-5793(76)80996-9 · Cited by 800
Self-citationHMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia
Oates, J. A., Wood, A. J. J., & Grundy, S. M. (1988) · New England Journal of Medicine · doi:10.1056/nejm198807073190105 · Cited by 760
Influence of nicotinic acid on serum cholesterol in man
Altschul, R., Hoffer, A., & Stephen, J. D. (1955) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(55)90070-9 · Cited by 726
Research works printed but not linked: 5
- 1988, The Lipid Research Clinics Coronary Primary Prevention Trial Results. 1. Reduction in the incidence of coronary heart disease, JAMA., 251, 351
- Taupitz, 1959, The effects of estrogens on the serum cholesterol of male rats, Symp. Deut. Ges. En-dokrinol., 430
- Endo, 1978, Effects of ML-236B, a competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase, on cholesterol metabolism, Adv. Exp. Med. Biol., 109, 376
- Shigematsu, 1979, Treatment of hypercholesterolemia with an HMG-CoA reductase inhibitor (CS-500). I. Phase I study in normal subjects, Geriat. Med. (Japan)., 17, 1564
- Alberts, 1988, Lovastatin and simvastatin, Cah. Nutr. Diet., 23, 231
Cited by
Sorted by citations
Triglycerides and cardiovascular disease
Nordestgaard, B. G., & Varbo, A. (2014) · The Lancet · doi:10.1016/s0140-6736(14)61177-6 · Cited by 1,419
The role of natural product chemistry in drug discovery
Butler, M. S. (2004) · Journal of Natural Products · doi:10.1021/np040106y · Cited by 1,381
Nordestgaard, B. G. (2016) · Circulation Research · doi:10.1161/circresaha.115.306249 · Cited by 1,116
Natural products to drugs: natural product-derived compounds in clinical trials
Butler, M. S. (2008) · Natural Product Reports · doi:10.1039/b514294f · Cited by 1,086
A Tale of Coronary Artery Disease and Myocardial Infarction
Nabel, E. G., & Braunwald, E. (2012) · New England Journal of Medicine · doi:10.1056/nejmra1112570 · Cited by 1,024
Metadata
- Authors
- Endo, A.
- Corresponding author
- Endo, A
- ORCID
- Endo, A
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1992-11
- Volume
- 33
- Issue
- 11
- Pages
- 1569-1582
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2148463229
- Cited by
- 847
- References
- 114
- Citations by year
- 2026: 11 · 2025: 19 · 2024: 31 · 2023: 22 · 2022: 25 · 2021: 26 · 2020: 23 · 2019: 20 · 2018: 35 · 2017: 28 · 2016: 37 · 2015: 41 · 2014: 39 · 2013: 43 · 2012: 35
- FWCI
- 16.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Lipid Research (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Pharmacology (medical) › Historical Medical Research and Treatments
- Keywords
- statins, cholesterol-lowering drugs, drug discovery, drug development
- MeSH terms
- Animals, Anticholesteremic Agents, Humans, Hypercholesterolemia, Lovastatin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, History, 20th Century
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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