Role of serotonin and other neurotransmitter receptors in brain development: basis for developmental pharmacology
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Trajectories of brain development: point of vulnerability or window of opportunity?
Andersen, S. L. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00005-8 · Cited by 1,503 · see citing works
“The action of some of these factors will be discussed as they influence trajectories of brain development via direct or indirect actions on the development of their own systems [227].”
BackgroundEstrogen Actions in the Central Nervous System
McEwen, B. S., & Alves, S. E. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0365 · Cited by 1,483 · see citing works
“Serotonin neurons of the midbrain/brainstem raphe nuclei are among the earliest neuronal phenotype to become differentiated during CNS development, and serotonin is believed to act as a regulatory/developmental agent (176, 177).”
BackgroundAdult brain neurogenesis and psychiatry: a novel theory of depression
Jacobs, B. L., van Praag, H., & Gage, F. H. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000712 · Cited by 964 · see citing works
Serotonin receptor 1A knockout: An animal model of anxiety-related disorder
Ramboz, S., Oosting, R. S., Amara, D. A., Kung, H. F., Blier, P., Mendelsohn, M. M., Mann, J. J., Brunner, D., & Hen, R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.24.14476 · Cited by 813 · see citing works
Neurotransmitters as growth regulatory signals: role of receptors and second messengers
Lauder, J. M. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90162-f · Cited by 806 · see citing works
Elevated anxiety and antidepressant-like responses in serotonin 5-HT 1A receptor mutant mice
Heisler, L. K., Chu, H.-M., Brennan, T. J., Danao, J. A., Bajwa, P., Parsons, L. H., & Tecott, L. H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.15049 · Cited by 704 · see citing works
Fetal Nicotine or Cocaine Exposure: Which One is Worse?
Slotkin, T. A. (1998) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37495-6 · Cited by 676 · see citing works
“The phenotypic expression of the ability to manufacture neurotransmitters or their receptors is a common feature of developing cells and even occurs in nonneuronal cells, in which it is now clear that transmitter chemicals play roles outside the realm of classical synaptic communication (Lauder, 1985; Whitaker-Azmitia…”
BackgroundBrezun, J. M., & Daszuta, A. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00693-9 · Cited by 549 · see citing works
Slotkin, T. A. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2003.06.001 · Cited by 544 · see citing works
“Keywords: Tobacco smoke; Neurotoxicity; Neurotransmitters Beginning in the 1960s, Buznikov et al. (1964, 1970) system (Lauder, 1985; Whitaker-Azmitia, 1991).”
Serotonin and brain development: role in human developmental diseases
Whitaker-Azmitia, P. M. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00615-3 · Cited by 506 · see citing works
Self-citationImpaired spatial and sequential learning in rats treated neonatally with d ‐fenfluramine
Morford, L. L., Inman-Wood, S. L., Gudelsky, G. A., Williams, M. T., & Vorhees, C. V. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02100.x · Cited by 454 · see citing works
“The neurotrophic effects of 5-HT play a role in embryogenesis (Lauder, 1988) and neuronal differentiation (Whitaker-Azmitia, 1991; Broening & Slikker, 1998; Frost & Cadet, 2000).”
BackgroundHypothalamic dopamine and serotonin in the regulation of food intake
Meguid, M. M., Fetissov, S. O., Varma, M., Sato, T., Zhang, L., Laviano, A., & Fanelli, F. R. (2000) · Nutrition · doi:10.1016/s0899-9007(00)00449-4 · Cited by 423 · see citing works
Schmidt, B. J., & Jordan, L. M. (2000) · Brain Research Bulletin · doi:10.1016/s0361-9230(00)00402-0 · Cited by 425 · see citing works
Potential developmental neurotoxicity of pesticides used in Europe
Bjørling-Poulsen, M., Andersen, H. R., & Grandjean, P. (2008) · Environmental Health · doi:10.1186/1476-069x-7-50 · Cited by 407 · see citing works
Serotonin as a developmental signal
Whitaker-Azmitia, P. M., Druse, M., Walker, P., & Lauder, J. M. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(96)00071-x · Cited by 356 · see citing works
Self-citationNeonatal Antidepressant Exposure has Lasting Effects on Behavior and Serotonin Circuitry
Maciąg, D., Simpson, K. L., Coppinger, D., Lu, Y., Wang, Y., Lin, R. C. S., & Paul, I. A. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300823 · Cited by 302 · see citing works
“Thus, the developing CNS during the prenatal and early postnatal periods is uniquely vulnerable to neurobiological teratogenicity due to exogenous drug exposure (Lauder, 1990; Whitaker-Azmitia, 1991).”
BackgroundMazer, C., Muneyyirci, J., Taheny, K., Raio, N., Borella, A., & Whitaker‐Azmitia, P. M. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00297-7 · Cited by 287 · see citing works
Self-citationDevelopmental cholinotoxicants: nicotine and chlorpyrifos
Slotkin, T. A. (1999) · Environmental Health Perspectives · doi:10.1289/ehp.99107s171 · Cited by 292 · see citing works
The recombinant 5‐HT 1A receptor: G protein coupling and signalling pathways
Raymond, J. R., Mukhin, Y. V., Gettys, T. W., & Garnovskaya, M. N. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702723 · Cited by 239 · see citing works
“Furthermore, in glial cells, endogenous 5-HT1A receptors stimulate secretion of the S100 protein, which has been shown to promote the growth of serotoninergic neurons (Lauder, 1993; Whitaker-Azmitia, 1991).”
BackgroundDopamine and noradrenaline control distinct functions in rodent microglial cells
Färber, K., Pannasch, U., & Kettenmann, H. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.01.003 · Cited by 238 · see citing works
5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus
Radley, J. J., & Jacobs, B. L. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03477-7 · Cited by 231 · see citing works
Direct and indirect cellular effects of aspartame on the brain
Humphries, P., Pretorius, E., & Naudé, H. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602866 · Cited by 220 · see citing works
Maturation of the Mammalian Respiratory System
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Slotkin, T. A. (2008) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2007.09.002 · Cited by 206 · see citing works
From oocyte to neuron: Do neurotransmitters function in the same way throughout development?
Buznikov, G. A., Shmukler, Y. B., & Lauder, J. M. (1996) · Cellular and Molecular Neurobiology · doi:10.1007/bf02152056 · Cited by 195 · see citing works
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Whitaker‐Azmitia, P. M., Clarke, C., & Azmitia, E. C. (1993) · Synapse · doi:10.1002/syn.890140303 · Cited by 181 · see citing works
Self-citationHansson, S. R., Mezey, É., & Hoffman, B. J. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00444-2 · Cited by 170 · see citing works
Norrholm, S. D., & Ouimet, C. C. (2001) · Synapse · doi:10.1002/syn.10006 · Cited by 164 · see citing works
Aldridge, J. E., Seidler, F. J., & Slotkin, T. A. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6713 · Cited by 162 · see citing works
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“As a general rule, serotonergic receptors in both humans and rats attain peak levels in fetal or early neonatal life and then decrease to adult levels [69].”
BackgroundNicotine Evokes Cell Death in Embryonic Rat Brain during Neurulation
Roy, T. S., Andrews, J. E., Seidler, F. J., & Slotkin, T. A. (1998) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37911-x · Cited by 147 · see citing works
“…acting as trophic substances, typically elicit biphasic developmental actions, promoting cell division at early stages but fostering the switch from replication to differentiation later in development (Buznikov et al., 1970; Lauder, 1985; Slotkin et al., 1987c, 1988a,b; Whitaker-Azmitia, 1991).”
Adult brain neurogenesis and depression
Jacobs, B. L. (2002) · Brain, Behavior, and Immunity · doi:10.1016/s0889-1591(02)00015-6 · Cited by 147 · see citing works
Evolutionary ancient roles of serotonin: long-lasting regulation of activity and development
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“In cell culture, elevated levels of serotonin decrease neuronal branching (Whitaker-Azmitia and Azmitia, 1986; Whitaker-Azmitia, 1991), which contrasts findings obtained from adult exposure studies showing antidepressantenhanced neurogenesis (Gould, 1999; Malberg et al.”
BackgroundBroening, H. W., Morford, L. L., Inman-Wood, S. L., Fukumura, M., & Vorhees, C. V. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-09-03228.2001 · Cited by 143 · see citing works
“MDMA may affect the developing brain differently, because 5-HT has neurotrophic effects before the maturation of its neurotransmitter function (Lauder and Krebs, 1978; Lauder et al., 1983; Lauder, 1988; Whitaker-Azmitia, 1991).”
BackgroundAldridge, J. E., Seidler, F. J., Meyer, A., Thillai, I., & Slotkin, T. A. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6489 · Cited by 142 · see citing works
The 5-HT1A receptor: Signaling, desensitization, and gene transcription
Albert, P. R., Lembo, P. M. C., STORRING, J., Charest, A., & Saucier, C. (1996) · Neuropsychopharmacology · doi:10.1016/s0893-133x(96)80055-8 · Cited by 131 · see citing works
Bou, C., Lajard, A.-M., Monteau, R., Maeyer, E. D., Seif, I., Lanoir, J., & Hilaire, G. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-12-04646.2000 · Cited by 127 · see citing works
“…that is expressed from an early embryonic age and is involved in several nervous maturational processes and functions (Lauder and Krebs, 1978; Vogt, 1982; Lauder et al., 1985; Whitaker-Azmitia, 1991; Hamon and Gozlan, 1993; Lauder, 1993; Hoyer et al., 1994; Peroutka, 1994; Levitt et al., 1997).”
BackgroundRen‐Patterson, R. F., Cochran, L. W., Holmes, A., Sherrill, S., Huang, S., Tolliver, T. J., Lesch, K., Lu, B., & Murphy, D. L. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20410 · Cited by 126 · see citing works
“…behaviors; nociception Serotonin (5-HT) is an important morphogenetic contributor to brain development before synapses are formed, in addition to its subsequent role as a neurotransmitter (Lauder, 1990; Whitaker-Azmitia, 1991; Turlejski, 1996; Whitaker-Azmitia, 2001; Gaspar et al., 2003).”
BackgroundInhibitory Effect of Hippocampal 5-HT1A Receptors on Human Explicit Memory
Yasuno, F., Suhara, T., Nakayama, T., Ichimiya, T., Okubo, Y., Takano, A., Ando, T., Inoue, M., Maeda, J., & Suzuki, K. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.2.334 · Cited by 123 · see citing works
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Psychobiology of childhood maltreatment: effects of allostatic load?
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Whitaker‐Azmitia, P. M., Zhang, X., & Clarke, C. (1994) · Neuropsychopharmacology · doi:10.1038/npp.1994.42 · Cited by 109 · see citing works
“In addition, adult behaviors can be dependent upon chemical imprinting during develop ment; the level of a neurotransmitter has to be at the appropriate level at a certain developmental stage for subsequent behaviors to develop properly, meaning that the neurochemical and behavioral change do not need to coexist (Whi…”
BackgroundSelf-citationSerotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals
Djavadian, R. L. (2004) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2004-1505 · Cited by 108 · see citing works
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“…of cell replication and differentiation, synaptic outgrowth, and apoptosis (Shaywitz and Greenberg, 1999; Stachowiak et al, 2003) and is a common site for disruption of brain development by neuroteratogens (Levitt et al, 1997; Slotkin et al, 2003a; Whitaker-Azmitia, 1991; Yanai et al, 2002).”
BackgroundAlpha-2 adrenergic receptor development in rat CNS: an autoradiographic study
Happe, H. K., Coulter, C. L., Gerety, M. E., et al. (2003) · Neuroscience · doi:10.1016/j.neuroscience.2003.09.004 · Cited by 101 · see citing works
The Main Features of Central 5-HT1A Receptors
Hamon, M. (2000) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-60921-3_9 · Cited by 95 · see citing works
Perireceptor events in olfaction
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Developmental Neurotoxicity of Organophosphates
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[18F]MPPF as a tool for the in vivo imaging of 5-HT1A receptors in animal and human brain
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“…below), high levels of expression of 5-HT1A receptor in areas of the neonate brain that are devoid of receptor in the adult and at times preceding substantial serotonergic innervation intimate that the receptors might be involved in neural development (Whitaker-Azmitia, 1991; Lauder, 1993).”
BackgroundYohn, N. L., & Blendy, J. A. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.11 · Cited by 87 · see citing works
Risks of using SSRI / SNRI antidepressants during pregnancy and lactation
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“The reason this is important is that 5HT plays a critical morphogenetic role in the developing brain (Lauder, 1985; Whitaker-Azmitia, 1991; Dreyfus, 1998).”
Cameron, J. L. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1308.012 · Cited by 83 · see citing works
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“At the present time physiological roles for astrocytic 5- HT7 receptors remain speculative although these cells have been suggested to play a role in the development of the 5- hydroxytryptaminergic system within the central nervous system (Whitaker-Azmitia, 1991).”
BackgroundThe Psychopharmacology of Obsessive Compulsive Disorder: Implications for Treatment and Pathogenesis
McDougle, C. J., Goodman, W. K., Leckman, J. F., & Price, L. H. (1993) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30148-5 · Cited by 80 · see citing works
Behavioral and magnetic resonance spectroscopic studies in the rat hyperserotonemic model of autism
Kahne, D. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00673-4 · Cited by 78 · see citing works
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“The sero- tonin receptor subtype that has been the most closely linked to both neuropsychiatric disorders such as schizophrenia (Vollenweider et al., 1998), and working memory (Williams et al., 2002), is the 5-HT2A receptor.”
BackgroundRelationship of neuroendocrine cells of prostate and serotonin to benign prostatic hyperplasia
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Development and Characterization of Monoclonal Antibodies Specific to the Serotonin 5-HT 2A Receptor
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Neonatal S100B Protein Levels After Prenatal Exposure to Selective Serotonin Reuptake Inhibitors
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Understanding Developmental Pharmacodynamics
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Cell Signaling as a Target and Underlying Mechanism for Neurobehavioral Teratogenesis
Yanai, J., Vatury, O. M., & Slotkin, T. A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04188.x · Cited by 59 · see citing works
Serotonin-2 receptors in the CNS of alcohol-preferring and -nonpreferring rats
McBride, W. J., Chernet, E., Rabold, J. A., Lumeng, L., & Li, T. (1993) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(93)90554-7 · Cited by 55 · see citing works
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“For instance, the neurotransmitters dopamine (DA), serotonin (5-HT) and gamma-aminobutyric acid (GABA) are all known to affect NSC/NPC proliferation during early brain development and in the adult brain (Vicini, 2008; Whitaker-Azmitia, 1991).”
BackgroundAL‐SHAMMA, H. A., & Vries, G. J. D. (1996) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(199601)29:1 · Cited by 45 · see citing works
Astrocytic β2-adrenergic receptors: From physiology to pathology
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de Castro, R. M., Medeiros, J. M. B., da Silva, C. M., Ferreira, L. M. P., Guedes, R. C. A., Filho, J. E. C., & Costa, J. A. D. I. (2001) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2001000100015 · Cited by 53 · see citing works
“Furthermore, experimental evidence indicates that serotonin can influence embryogenesis and growth (7,8) presumably by acting as a developmental signal (9) or a neurotrophic factor (10).”
BackgroundLocomotor Network Maturation Is Transiently Delayed in the MAOA-Deficient Mouse
Cazalets, J., Gardette, M., & Hilaire, G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.4.2468 · Cited by 53 · see citing works
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Self-citationPerinatal Development of the Motor Systems Involved in Postural Control
Vinay, L., Ben‐Mabrouk, F., Brocard, F., Clarac, F., Jean-Xavier, C., Pearlstein, É., & Pflieger, J. (2005) · Neural Plasticity · doi:10.1155/np.2005.131 · Cited by 50 · see citing works
“The monoaminergic pathways, which are among the earliest axonal systems to invade the developing spinal cord (Commissiong, 1983; Kudo et al., 1993; Lakke, 1997), can play such a role (Whitaker-Azmitia, 1991, 1996; Gaspar et al., 2003 ).”
BackgroundDevelopmental Cholinotoxicants: Nicotine and Chlorpyrifos
Slotkin, T. A. (1999) · Environmental Health Perspectives · doi:10.2307/3434474 · Cited by 50 · see citing works
Neonatal treatment with fluoxetine reduces depressive behavior induced by forced swim in adult rats
Mendes‐da‐Silva, C., de Souza, S. L., Medeiros, J. M. B., Freitas-Silva, S. R., Antunes, D. E. C., Cunha, A. D. U., Ribas, V. R., de França, M. F. S., Nogueira, M. I., & Manhães‐de‐Castro, R. (2002) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2002000600008 · Cited by 49 · see citing works
Molecular Mechanisms of Amitraz Mammalian Toxicity: A Comprehensive Review of Existing Data
del Pino, J., Moyano-Cires, P. V., Anadón, M. J., Díaz, M. J. V., Lobo, M., Capo, M. A., & Frejo, M. T. (2015) · Chemical Research in Toxicology · doi:10.1021/tx500534x · Cited by 45 · see citing works
Sertraline delays the somatic growth and reflex ontogeny in neonate rats
Deiró, T. C. B. J., Manhães‐de‐Castro, R., Cabral-Filho, J. E., Medeiros, J. M. B., de Souza, S. L., Marinho, S. M. O. C., Manhães-de-Castro, F. M., Toscano, A. E., Jesus-Deiró, R. A., & Barros, K. M. F. T. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.10.003 · Cited by 46 · see citing works
Zhang, L., Guadarrama, L., Corona-Morales, A. A., Vega‐González, A., Rocha, L., & Escobar, A. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-200606000-00004 · Cited by 46 · see citing works
“There are several experimental evidences suggesting this regulation: 1) serotonin autoregulates development of neurons producing serotonin (7); 2) serotonin exerts effects on the development of target tissue (8); 3) changes in serotoninergic transmission alter gene expression of brain derived neurotrophic factor (9, 1…”
Background5‐HT1A receptor gene C −1019 G polymorphism and amygdala volume in borderline personality disorder
Zetzsche, D. A., Preuss, U. W., Bondy, B., Frodl, T., Zill, P., Schmitt, G., Koutsouleris, N., Rujescu, D., Born, C., Reiser, M. F., et al. (2007) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2007.00353.x · Cited by 45 · see citing works
“5-Hydroxytryptamine1A receptors were reported to mediate some of these effects (Duman et al. 2000; Huang & Herbert 2005; Whitaker-Azmitia 1991).”
BackgroundBiomarkers for major depression and its delineation from neurodegenerative disorders
Schneider, B., Prvulovic, D., Oertel‐Knöchel, V., Knöchel, C., Reinke, B., Grexa, M., Weber, B., & Hampel, H. J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.08.001 · Cited by 42 · see citing works
“…in the proliferative activity in the hippocampus: serotonin (5-HT), which has been shown to exert a neurogenic effect in the CNS during development (Whitaker-Azmitia, 1991), seems to exert a protective role in the hippocampus and attenuates the behavioral consequences of stress by activating…”
Transcriptomics and Other Omics Approaches to Investigate Effects of Xenobiotics on the Placenta
Rosenfeld, C. S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.723656 · Cited by 43 · see citing works
Balancing function vs. self defense: The CNS as an active regulator of immune responses
Carson, M. J., & Sutcliffe, J. G. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990101)55:1 · Cited by 99 · see citing works
Cellular Aspects of Trophic Actions in the Nervous System
Weisenhorn, D. M. V., Roback, J. D., Young, A. N., & Wainer, B. H. (1999) · International review of cytology · doi:10.1016/s0074-7696(08)61388-1 · Cited by 40 · see citing works
Penner, M. R., Leussis, M. P., Pinaud, R., CARREY, N. J., Robertson, H. A., & Brown, R. E. (2002) · Developmental Brain Research · doi:10.1016/s0165-3806(02)00308-5 · Cited by 40 · see citing works
Polli, F., Scharff, M. B., Ipsen, T. H., Aznar, S., Kohlmeier, K., & Andreasen, J. (2020) · Pharmacology, Biochemistry and Behavior · doi:10.1016/j.pbb.2020.172951 · Cited by 31 · see citing works
Grimaldi, B., Bonnin, A., Fillion, M., Ruat, M., Traiffort, É., & Fillion, G. (1998) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/pl00005184 · Cited by 38 · see citing works
Azmitia, E. C., Griffin, W. S. T., Marshak, D. R., Eldik, L. J. V., & Whitaker‐Azmitia, P. M. (1992) · Progress in brain research · doi:10.1016/s0079-6123(08)61773-2 · Cited by 38 · see citing works
Self-citationWoolston, A.-M., Wedderburn, J. F. S., & Sillar, K. T. (1994) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1994.0011 · Cited by 38 · see citing works
- Authors
- Whitaker-Azmitia, P. M.
- Venue
- Pharmacological Reviews
- Publisher
- Elsevier BV
- Published
- 1991-12
- Volume
- 43
- Issue
- 4
- Pages
- 553-561
- ISSN
- 0031-6997 (ISSN-L)
- OpenAlex
- W2230711217
- Cited by
- 226
- References
- 0
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 4 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 3 · 2016: 1 · 2015: 5 · 2014: 5 · 2013: 5 · 2012: 3
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacological Reviews (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- serotonin, neurotransmitter receptors, brain development, developmental pharmacology
- MeSH terms
- Animals, Brain, Humans, Receptors, Serotonin, Developmental Biology, Receptors, Neurotransmitter
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