Regulation of Auxin Response by the Protein Kinase PINOID
Open accessAbstract
Arabidopsis plants carrying mutations in the PINOID (PID) gene have a pleiotropic shoot phenotype that mimics that of plants grown on auxin transport inhibitors or of plants mutant for the auxin efflux carrier PINFORMED (PIN), with defects in the formation of cotyledons, flowers, and floral organs. We have cloned PID and find that it is transiently expressed in the embryo and in initiating floral anlagen, demonstrating a specific role for PID in promoting primordium development. Constitutive expression of PID causes a phenotype in both shoots and roots that is similar to that of auxin-insensitive plants, implying that PID, which encodes a serine-threonine protein kinase, negatively regulates auxin signaling.
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MP transcript accumulation in vegetative pid-9 shoot apices did not deviate from the wild type.
“MP transcript accumulation in vegetative pid-9 shoot apices did not deviate from the wild type (Figures 3G and 3H), as also observed in inflorescence apices (Christensen et al., 2000).”
From Auxin Depletion from the Leaf Axil Conditions Competence for Axillary Meristem Formation in <i>Arabidopsis</i> and Tomato (2014) · cites this paper as Christensen et al., 2000
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“Arabidopsis lines used in this research are: pid-9 (Christensen et al., 2000), pin1 (Salk_47613), aux lax1 lax2 (Bainbridge et al.”
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- Authors
- Christensen, S. K., Dagenais, N., Chory, J., & Weigel, D.
- Affiliations
- Salk Institute for Biological Studies (US)
- Corresponding author
- Chory, Joanne
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2000-02
- Volume
- 100
- Issue
- 4
- Pages
- 469-478
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2138150898
- Cited by
- 501
- References
- 0
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 11 · 2023: 9 · 2022: 11 · 2021: 6 · 2020: 9 · 2019: 24 · 2018: 12 · 2017: 27 · 2016: 10 · 2015: 8 · 2014: 26 · 2013: 21 · 2012: 14
- FWCI
- 39.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant nutrient uptake and metabolism
- Keywords
- PINOID, auxin response, auxin transport, auxin efflux carriers, serine/threonine kinase, auxin signaling, floral organ development, cotyledon development, shoot development, root development, embryonic development, Arabidopsis thaliana
- MeSH terms
- Amino Acid Sequence, Base Sequence, Indoleacetic Acids, Molecular Sequence Data, Biomarkers, Gene Expression, Protein Serine-Threonine Kinases, Arabidopsis, Meristem, DNA, Plant, Arabidopsis Proteins
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