p53, the Cellular Gatekeeper for Growth and Division

WAF1, a potential mediator of p53 tumor suppression

El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., & Vogelstein, B. (1993) · Cell · doi:10.1016/0092-8674(93)90500-p · Cited by 8,321

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., & Bradley, A. (1992) · Nature · doi:10.1038/356215a0 · Cited by 4,649

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki, M., & Reed, J. C. (1995) · Cell · doi:10.1016/0092-8674(95)90412-3 · Cited by 4,063

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., & Fornace, A. J. (1992) · Cell · doi:10.1016/0092-8674(92)90593-2 · Cited by 3,047

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

Lowe, S. W., Ruley, H. E., Jacks, T., & Housman, D. E. (1993) · Cell · doi:10.1016/0092-8674(93)90719-7 · Cited by 2,911

p53 is required for radiation-induced apoptosis in mouse thymocytes

Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., & Jacks, T. (1993) · Nature · doi:10.1038/362847a0 · Cited by 2,864

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Cho, Y., Gorina, S., Jeffrey, P. D., & Pavletich, N. P. (1994) · Science · doi:10.1126/science.8023157 · Cited by 2,559

p53: puzzle and paradigm.Preprint

Ko, L. J., & Prives, C. L. (1996) · Genes & Development · doi:10.1101/gad.10.9.1054 · Cited by 2,346

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Graeber, T. G., Osmanian, C., Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W., & Giaccia, A. J. (1996) · Nature · doi:10.1038/379088a0 · Cited by 2,300

Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., & Pavletich, N. P. (1996) · Science · doi:10.1126/science.274.5289.948 · Cited by 2,206

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Deng, C., Zhang, P., Wade Harper, J., Elledge, S. J., & Leder, P. (1995) · Cell · doi:10.1016/0092-8674(95)90039-x · Cited by 2,113

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

Yonish-Rouach, E., Resnftzky, D., Lotem, J., Sachs, L., Kimchi, A., & Oren, M. (1991) · Nature · doi:10.1038/352345a0 · Cited by 2,079

Amplification of a gene encoding a p53-associated protein in human sarcomas

Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., & Vogelstein, B. (1992) · Nature · doi:10.1038/358080a0 · Cited by 1,949

Sunburn and p53 in the onset of skin cancer

Ziegler, A., Jonason, A. S., Leffellt, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., Remington, L., Jacks, T., & Brash, D. E. (1994) · Nature · doi:10.1038/372773a0 · Cited by 1,497

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

de Oca Luna, R. M., Wagner, D. S., & Lozano, G. (1995) · Nature · doi:10.1038/378203a0 · Cited by 1,420

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

Livingstone, L. R., White, A., Sprouse, J., Livanos, E., Jacks, T., & Tlsty, T. D. (1992) · Cell · doi:10.1016/0092-8674(92)90243-6 · Cited by 1,328

Gain of function mutations in p53

Dittmer, D., Pati, S., Zambetti, G., Chu, S., Teresky, A. K., Moore, M., Finlay, C., & Levine, A. J. (1993) · Nature Genetics · doi:10.1038/ng0593-42 · Cited by 894

p53-Dependent apoptosis suppresses tumor growth and progression in vivo

Symonds, H., Krall, L., Remington, L., Saenz-Robles, M., Lowe, S., Jacks, T., & Van Dyke, T. (1994) · Cell · doi:10.1016/0092-8674(94)90534-7 · Cited by 880

Induction of the growth inhibitor IGF-binding protein 3 by p53

Buckbinder, L., Talbott, R. L., Velasco-Miguel, S., Takenaka, I. M., Faha, B., Seizinger, B. R., & Kley, N. (1995) · Nature · doi:10.1038/377646a0 · Cited by 869

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.Preprint

Debbas, M. E., & White, E. (1993) · Genes & Development · doi:10.1101/gad.7.4.546 · Cited by 866

Database of p53 gene somatic mutations in human tumors and cell lines.

Hollstein, M. C., Rice, K., Greenblatt, M. S., Soussi, T., Fuchs, R., Sørlie, T., Hovig, E. J., Smith‐Sørensen, B., Montesano, R., & Harris, C. C. (1994) · Europe PMC (PubMed Central) · Cited by 858

p53-Dependent apoptosis in the absence of transcriptional activation of p53-target genes

Caelles, C., Helmberg, A., & Karin, M. (1994) · Nature · doi:10.1038/370220a0 · Cited by 843

p53 and E2F-1 cooperate to mediate apoptosis.

Wu, X., & Levine, A. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.9.3602 · Cited by 840

Abnormal Centrosome Amplification in the Absence of p53

Fukasawa, K., Choi, T., Kuriyama, R., Rulong, S., & Woude, G. F. V. (1996) · Science · doi:10.1126/science.271.5256.1744 · Cited by 794

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

Aas, T., Børresen‐Dale, A., Geisler, S. B., Smith‐Sørensen, B., Johnsen, H., Varhaug, J. E., Akslen, L. A., & Lønning, P. E. (1996) · Nature Medicine · doi:10.1038/nm0796-811 · Cited by 736

A p53-Dependent Mouse Spindle Checkpoint

Cross, S. M., Sanchez, C. A., Morgan, C. A., Schimke, M. K., Ramel, S., Idzerda, R. L., Raskind, W. H., & Reid, B. J. (1995) · Science · doi:10.1126/science.7871434 · Cited by 660

Crystal Structure of the Tetramerization Domain of the p53 Tumor Suppressor at 1.7 Angstroms

Jeffrey, P. D., Gorina, S. S., & Pavletich, N. P. (1995) · Science · doi:10.1126/science.7878469 · Cited by 560

p53 modulation of TFIIH–associated nucleotide excision repair activity

Wang, X. W., Yeh, H., Schaeffer, L., Roy, R., Moncollin, V., Egly, J., Wang, Z., Friedberg, E. C., Evans, M. K., Taffe, B. G., et al. (1995) · Nature Genetics · doi:10.1038/ng0695-188 · Cited by 555

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.Preprint

Haupt, Y., Rowan, S., Shaulian, E., Vousden, K. H., & Oren, M. (1995) · Genes & Development · doi:10.1101/gad.9.17.2170 · Cited by 547

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.Preprint

Wagner, A. J., Kokontis, J. M., & Hay, N. (1994) · Genes & Development · doi:10.1101/gad.8.23.2817 · Cited by 541

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.Preprint

Linke, S. P., Clarkin, K., Leonardo, A. D., Tsou, A.-P., & Wahl, G. M. (1996) · Genes & Development · doi:10.1101/gad.10.8.934 · Cited by 531

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

Walker, K. K., & Levine, A. J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.26.15335 · Cited by 477

Genetic determinants of p53-induced apoptosis and growth arrest.Preprint

Polyák, K., Waldman, T. A., He, T., Kinzler, K. W., & Vogelstein, B. (1996) · Genes & Development · doi:10.1101/gad.10.15.1945 · Cited by 458

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors

Kemp, C. J., Donehower, L. A., Bradley, A., & Balmain, A. (1993) · Cell · doi:10.1016/0092-8674(93)90461-x · Cited by 456

p53 Transcriptional Activation Mediated by Coactivators TAF II 40 and TAF II 60

Thut, C. J., Chen, J.-L., Klemm, R. D., & Tjian, R. (1995) · Science · doi:10.1126/science.7809597 · Cited by 439

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

Lee, S., Elenbaas, B., Levine, A. J., & Griffith, J. D. (1995) · Cell · doi:10.1016/s0092-8674(05)80006-6 · Cited by 405

Cooperative tumorigenic effects of germline mutations in Rb and p53

Williams, B. O., Remington, L., Albert, D. M., Mukai, S., Bronson, R. T., & Jacks, T. (1994) · Nature Genetics · doi:10.1038/ng0894-480 · Cited by 370

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

Jayaraman, L., & Prives, C. L. (1995) · Cell · doi:10.1016/s0092-8674(05)80007-8 · Cited by 343

Human TAFII31 protein is a transcriptional coactivator of the p53 protein.

Lu, H., & Levine, A. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.5154 · Cited by 301

Allosteric activation of latent p53 tetramers

Hupp, T. R., & Lane, D. P. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00195-0 · Cited by 300

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53.Preprint

Howes, K. A., Ransom, N. L., Papermaster, D. S., Lasudry, J., Albert, D. M., & Windle, J. J. (1994) · Genes & Development · doi:10.1101/gad.8.11.1300 · Cited by 299

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.Preprint

Donehower, L. A., Godley, L. A., Aldaz, C. M., Pyle, R., Shi, Y. P., Pinkel, D., Gray, J. W., Bradley, A., Medina, D., & VARMUS, H. E. (1995) · Genes & Development · doi:10.1101/gad.9.7.882 · Cited by 277

A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis

Friedlander, P. A., Haupt, Y., Prives, C. L., & Oren, M. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.9.4961 · Cited by 277

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.Preprint

Guidos, C. J., Williams, C. J., Grandal, I., Knowles, G. C., Huang, M. T. F., & Danska, J. S. (1996) · Genes & Development · doi:10.1101/gad.10.16.2038 · Cited by 276

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis.Preprint

Maheswaran, S., Englert, C., Bennett, P., Heinrich, G., & Haber, D. A. (1995) · Genes & Development · doi:10.1101/gad.9.17.2143 · Cited by 248

A teratologic suppressor role for p53 in benzo(a)pyrene–treated transgenic p53-deficient mice

Nicol, C. J. B., Harrison, M. L., Laposa, R. R., Gimelshtein, I. L., & Wells, P. G. (1995) · Nature Genetics · doi:10.1038/ng0695-181 · Cited by 247

Essential role for p53-mediated transcription in E1A-induced apoptosis.Preprint

Sabbatini, P., Lin, J., Levine, A. J., & White, E. (1995) · Genes & Development · doi:10.1101/gad.9.17.2184 · Cited by 215

A functionally inactive p53 protein interatocarcinoma cells is activated by either DNA damage or cellular differentiation

Lutzker, S. G., & Levine, A. J. (1996) · Nature Medicine · doi:10.1038/nm0796-804 · Cited by 206

Growth Suppression of Friend Virus-Transformed Erythroleukemia Cells by p53 Protein Is Accompanied by Hemoglobin Production and Is Sensitive to Erythropoietin

Johnson, P., Chung, S. W., & Benchimol, S. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.3.1456-1463.1993 · Cited by 140

p53 dependent growth suppression by the c-Abl nuclear tyrosine kinase.

Goga, A., Liu, X., Hambuch, T. M., Senechal, K., Major, E., Berk, A. J., Witte, O. N., & Sawyers, C. L. (1995) · PubMed · Cited by 133

Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes

Brown, C. R., Welch, W. J., Doxsey, S., & White, E. (1994) · Journal of Cellular Physiology · doi:10.1002/jcp.1041600107 · Cited by 113

Gas1-Induced Growth Suppression Requires a Transactivation-Independent p53 Function

Sal, G. D., Ruaro, E. M., Utrera, R., Cole, C. N., Levine, A. J., & Schneider, C. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.12.7152 · Cited by 98

Mutant p53 rescues human diploid cells from senescence without inhibiting the induction of SDI1/WAF1.

BOND, J. A., Blaydes, J. P., Rowson, J., Haughton, M. F., Smith, J. R., Wynford‐Thomas, D., & Wyllie, F. S. (1995) · PubMed · Cited by 75

A novel p53 germline alteration identified in a late onset breast cancer kindred.

Sun, X. F., Jóhannsson, Ó. Þ., Håkansson, S., et al. (1996) · PubMed · Cited by 35

Functions of the p53 Protein in Growth Regulation and Tumor SuppressionPreprint

Lin, J., Wu, X., Chen, J., Chang, A., & Levine, A. J. (1994) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1994.059.01.026 · Cited by 32

The hallmarks of cancer

Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219

Surfing the p53 network

Vogelstein, B., Lane, D., & Levine, A. J. (2000) · Nature · doi:10.1038/35042675 · Cited by 6,607

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., et al. (2004) · Science · doi:10.1126/science.1092472 · Cited by 4,661

Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage

Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., & Vogelstein, B. (1998) · Science · doi:10.1126/science.282.5393.1497 · Cited by 2,803

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

Gu, W., & Roeder, R. G. (1997) · Cell · doi:10.1016/s0092-8674(00)80521-8 · Cited by 2,559

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Modified straight division: A computer implementation of multiple-precision division

Parthasarathi, R., & Jhunjhunwala, A. (1995) · Microprocessing and Microprogramming · doi:10.1016/0165-6074(94)00091-n · Cited by 1

Καινοτόμες τεχνολογικές εφαρμογές για άτομα με αναπηρία στο τμήμα δωματίων (Rooms Division) των ελληνικών ξενοδοχείων

Θεοχάρης, Ν. (2020) · doi:10.12681/eadd/47729

Climatic Division of Kantô District, Japan

Yoshino, M. M. (1967) · Annals of the Tohoku Geographical Association · doi:10.5190/tga1948.19.165 · Cited by 1

APA Division 47: Division 47 Presidents

(2012) · PsycEXTRA Dataset · doi:10.1037/e672072012-001