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Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD

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Baas, Annette F, Kuipers, Jeroen, van der Wel, Nicole N, Batlle, Eduard, Koerten, Henk K, Peters, Peter J, Clevers, Hans C·2004·Cell

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Citations

Cites

Research works printed but not linked: 46

  1. Anastasiadis, 2000, The p120 catenin family, J. Cell Sci., 113, 1319, 10.1242/jcs.113.8.1319 · DOI · Paper page
  2. Baas, 2003, Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD, EMBO J., 22, 3062, 10.1093/emboj/cdg292 · DOI · Paper page
  3. Bardeesy, 2002, Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation, Nature, 419, 162, 10.1038/nature01045 · DOI · Paper page
  4. Berryman, 1993, Ezrin is concentrated in the apical microvilli of a variety of epithelial cells whereas moesin is found primarily in endothelial cells, J. Cell Sci., 105, 1025, 10.1242/jcs.105.4.1025 · DOI · Paper page
  5. Boudeau, 2003, MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localise LKB1 in the cytoplasm, EMBO J., 22, 5102, 10.1093/emboj/cdg490 · DOI
  6. Bowerman, 1997, The maternal par genes and the segregation of cell fate specification activities in early Caenorhabditis elegans embryos, Development, 124, 3815, 10.1242/dev.124.19.3815 · DOI
  7. Cereijido, 1980, Structural and functional membrane polarity in cultured monolayers of MDCK cells, J. Membr. Biol., 52, 147, 10.1007/BF01869120 · DOI
  8. Cheng, 1995, Control of cleavage spindle orientation in Caenorhabditis elegans, Genetics, 139, 549, 10.1093/genetics/139.2.549 · DOI
  9. Collins, 2000, LKB1, a novel serine/threonine protein kinase and potential tumour suppressor is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo, Biochem. J., 345, 673, 10.1042/bj3450673 · DOI
  10. Fleming, 2000, Assembly of tight junctions during early vertebrate development, Semin. Cell Dev. Biol., 11, 291, 10.1006/scdb.2000.0179 · DOI
  11. Friederich, 1989, Villin induces microvilli growth and actin redistribution in transfected fibroblasts, Cell, 59, 461, 10.1016/0092-8674(89)90030-5 · DOI
  12. Friederich, 1990, From the structure to the function of villin, an actin-binding protein of the brush border, Bioessays, 12, 403, 10.1002/bies.950120902 · DOI
  13. Giardiello, 2000, Very high risk of cancer in familial Peutz-Jeghers syndrome, Gastroenterology, 119, 1447, 10.1053/gast.2000.20228 · DOI · Paper page
  14. Guo, 1996, Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo, Curr. Opin. Genet. Dev., 6, 408, 10.1016/S0959-437X(96)80061-X · DOI
  15. Hawley, 2003, Complexes between the LKB1 tumor suppressor, STRADalpha/beta and MO25alpha/beta are upstream kinases in the AMP-activated protein kinase cascade, J. Biol., 2, 28, 10.1186/1475-4924-2-28 · DOI
  16. Hemminki, 1998, A serine/threonine kinase gene defective in Peutz-Jeghers syndrome, Nature, 391, 184, 10.1038/34432 · DOI
  17. Jeghers, 1949, Generalised intestinal polyposis and melanin spots of oral mucosa, lips and digits, N. Engl. J. Med., 241, 992, 10.1056/NEJM194912292412601 · DOI · Paper page
  18. Jenne, 1998, Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase, Nat. Genet., 18, 38, 10.1038/ng0198-38 · DOI · Paper page
  19. Jishage, 2002, Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis, Proc. Natl. Acad. Sci. USA, 99, 8903, 10.1073/pnas.122254599 · DOI
  20. Karuman, 2001, The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death, Mol. Cell, 7, 1307, 10.1016/S1097-2765(01)00258-1 · DOI · Paper page
  21. Kemphues, 1988, Identification of genes required for cytoplasmic localization in early C. elegans embryos, Cell, 52, 311, 10.1016/S0092-8674(88)80024-2 · DOI · Paper page
  22. Kirby, 1990, Mutations in the par genes of Caenorhabditis elegans affect cytoplasmic reorganization during the first cell cycle, Dev. Biol., 142, 203, 10.1016/0012-1606(90)90164-E · DOI
  23. Marignani, 2001, LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest, J. Biol. Chem., 276, 32415, 10.1074/jbc.C100207200 · DOI
  24. Martin, 2003, A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity, Nature, 421, 379, 10.1038/nature01296 · DOI · Paper page
  25. Miyoshi, 2002, Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice, Cancer Res., 62, 2261
  26. Morton, 1992, par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis, Genetics, 130, 771, 10.1093/genetics/130.4.771 · DOI
  27. Nakau, 2002, Hepatocellular carcinoma caused by loss of heterozygosity in lkb1 gene knockout mice, Cancer Res., 62, 4549
  28. Ossipova, 2003, LKB1 (XEEK1) regulates Wnt signalling in vertebrate development, Nat. Cell Biol., 10, 889, 10.1038/ncb1048 · DOI
  29. Peters, 2001, Subcellular localization of Rab17 by cryo-immunogold electron microscopy in epithelial cells grown on polycarbonate filters, Methods Enzymol., 329, 210, 10.1016/S0076-6879(01)29081-8 · DOI
  30. Peutz, 1921, On a very remarkable case of familial polyposis of the mucous membrane of the intestinal tract and nasopharynx accompanied by peculiar pigmentation of the skin and mucous membranes, Ned. Tijdschr. Geneeskd., 10, 134
  31. Pinto, 1983, Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture, Biol. Cell., 47, 323
  32. Rossi, 2002, Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis, Proc. Natl. Acad. Sci. U.S.A., 99, 505, 10.1073/pnas.192301399 · DOI
  33. Sapkota, 2001, Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell growth, J. Biol. Chem., 276, 19469, 10.1074/jbc.M009953200 · DOI · Paper page
  34. Spicer, 2003, Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1, Oncogene, 22, 4752, 10.1038/sj.onc.1206669 · DOI
  35. Smith, 2001, LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1, Hum. Mol. Genet., 10, 2869, 10.1093/hmg/10.25.2869 · DOI
  36. Stevenson, 1986, Identification of ZO-1, J. Cell Biol., 103, 755, 10.1083/jcb.103.3.755 · DOI · Paper page
  37. Tiainen, 1999, Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest, Proc. Natl. Acad. Sci. USA, 96, 9248, 10.1073/pnas.96.16.9248 · DOI · Paper page
  38. Tiainen, 2002, Growth arrest by the LKB1 tumor suppressor, Hum. Mol. Genet., 11, 1497, 10.1093/hmg/11.13.1497 · DOI
  39. van de Wetering, 2002, The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells, Cell, 111, 241, 10.1016/S0092-8674(02)01014-0 · DOI · Paper page
  40. van de Wetering, 2003, Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector, EMBO Rep., 4, 609, 10.1038/sj.embor.embor865 · DOI · Paper page
  41. Van Meer, 1986, The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next, Nature, 322, 639, 10.1038/322639a0 · DOI
  42. Watts, 2000, The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry, Development, 127, 1467, 10.1242/dev.127.7.1467 · DOI
  43. Wodarz, 2002, Establishing cell polarity in development, Nat. Cell Biol., 4, E39, 10.1038/ncb0202-e39 · DOI
  44. Yeaman, 1999, New perspectives on mechanisms involved in generating epithelial cell polarity, Phys. Rev., 79, 73
  45. Ylikorkala, 2001, Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice, Science, 293, 1323, 10.1126/science.1062074 · DOI · Paper page
  46. Zahraoui, 2000, Tight junction, a platform for trafficking and signaling protein complexes, J. Cell Biol., 151, F31, 10.1083/jcb.151.5.F31 · DOI

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Metadata

Authors
Baas, A. F., Kuipers, J., van der Wel, N. N., Batlle, E., Koerten, H. K., Peters, P. J., & Clevers, H. C.
Venue
Cell
Publisher
Elsevier BV
Published
2004-02
Volume
116
Issue
3
Pages
457-466
ISSN
0092-8674 (ISSN-L)
OpenAlex
W2106302419
Cited by
508
References
2
FWCI
14.36
Type
journal article
Language
en
Open access
bronze

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