Phosphorylation by the β-Catenin/MAPK Complex Promotes 14-3-3-Mediated Nuclear Export of TCF/POP-1 in Signal-Responsive Cells in C. elegans

Wnt signaling and cancer

Polakis, P. (2000) · Genes & Development · doi:10.1101/gad.14.15.1837 · Cited by 3,183

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

Fornerod, M. W. J., Ohno, M., Yoshida, M., & Mattaj, I. W. (1997) · Cell · doi:10.1016/s0092-8674(00)80371-2 · Cited by 2,086

Specific interference by ingested dsRNA

Timmons, L., & Fire, A. Z. (1998) · Nature · doi:10.1038/27579 · Cited by 1,938

14-3-3 Proteins: Structure, Function, and Regulation

Fu, H., Subramanian, R. R., & Masters, S. C. (2000) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.40.1.617 · Cited by 1,596

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

Fukuda, M., Asano, S., Nakamura, T., Adachi, M., Yoshida, M., Yanagida, M., & Nishida, E. (1997) · Nature · doi:10.1038/36894 · Cited by 1,213

Exportin 1 (Crm1p) Is an Essential Nuclear Export Factor

Stade, K., Ford, C. S., Guthrie, C., & Weis, K. (1997) · Cell · doi:10.1016/s0092-8674(00)80370-0 · Cited by 1,145

Creation of Low-Copy Integrated Transgenic Lines in Caenorhabditis elegans

Praitis, V., Casey, E., Collar, D. C., & Austin, J. (2001) · Genetics · doi:10.1093/genetics/157.3.1217 · Cited by 817

Drosophila Tcf and Groucho interact to repress Wingless signalling activity

Cavallo, R. A., Cox, R. T., Moline, M. M., Roose, J., Polevoy, G. A., Clevers, H., Peifer, M., & Bejsovec, A. (1998) · Nature · doi:10.1038/26982 · Cited by 730

Evidence for a Role of CRM1 in Signal-Mediated Nuclear Protein Export

Ossareh‐Nazari, B., Bachelerie, F., & Dargemont, C. (1997) · Science · doi:10.1126/science.278.5335.141 · Cited by 713

Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos

Rocheleau, C. E., Downs, W. D., Lin, R., Wittmann, C., Bei, Y., Cha, Y.-H., Ali, M., Priess, J. R., & Mello, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80531-0 · Cited by 660

Systematic Discovery of New Recognition Peptides Mediating Protein Interaction

Neduva, N., Linding, R., Angrand, I., Stark, A., Masi, F. D., Gibson, T. J., Lewis, J., Serrano, L. G., & Russell, R. B. (2005) · Cited by 14

Regulation of asymmetric positioning of nuclei by Wnt and Src signaling and its roles in POP‐1/TCF nuclear asymmetry in Caenorhabditis elegans

Sugioka, K., & Sawa, H. (2010) · Genes to Cells · doi:10.1111/j.1365-2443.2010.01388.x · Cited by 13

Wnt/β‐catenin‐mediated transcriptional regulation

Parker, D. S., Blauwkamp, T. A., & Cadigan, K. M. (2007) · Advances in developmental biology · doi:10.1016/s1574-3349(06)17001-5 · Cited by 14

Neuronal specification in C. elegans : combining lineage inheritance with intercellular signaling

Barrière, A., & Bertrand, V. (2020) · Journal of Neurogenetics · doi:10.1080/01677063.2020.1781850 · Cited by 12

Asymmetric Wnt Pathway Signaling Facilitates Stem Cell-Like Divisions via the Nonreceptor Tyrosine Kinase FRK-1 inCaenorhabditis elegans

Mila, D., Calderón, A. G. T., Baldwin, A. T., Moore, K. M., Watson, M. J., Phillips, B. T., & Putzke, A. P. (2015) · Genetics · doi:10.1534/genetics.115.181412 · Cited by 10

β-Catenin–related protein WRM-1 is a multifunctional regulatory subunit of the LIT-1 MAPK complex

Yang, X., Karhadkar, T. R., Medina, J., Robertson, S. M., & Lin, R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416339112 · Cited by 8

Non-muscle myosin II is required for correct fate specification in the Caenorhabditis elegans seam cell divisions

Ding, S. S., & Woollard, A. C. S. (2017) · Scientific Reports · doi:10.1038/s41598-017-01675-7 · Cited by 9

Collaboration within the M1 aminopeptidase family promotes reproductive success in Caenorhabditis elegans

Althoff, M. J., Flick, K. F., & Trzepacz, C. (2014) · Development Genes and Evolution · doi:10.1007/s00427-014-0470-3 · Cited by 8

Extending from PARs inCaenorhabditis elegansto homologues inHaemonchus contortusand other parasitic nematodes

Nikolaou, S., & Gasser, R. B. (2006) · Parasitology · doi:10.1017/s0031182006001727 · Cited by 8

CMGSDB: integrating heterogeneous Caenorhabditis elegans data sources using compositional data mining

Pati, A., Jin, Y., Klage, K., Helm, R. F., Heath, L. S., & Ramakrishnan, N. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm804 · Cited by 7

Mammalian Nemo-like kinase enhances .BETA.-catenin-TCF transcription activity in human osteosarcoma and neuroblastoma cells

YASUDA, J., & ICHIKAWA, H. (2007) · Proceedings of the Japan Academy, Series B · doi:10.2183/pjab.83.16 · Cited by 6

Functional analyses of vertebrate TCF proteins in C. elegans embryos

Robertson, S. M., Lo, M., Odom, R. S., Yang, X., Medina, J., Huang, S., & Lin, R. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.04.012 · Cited by 6

Our evolving view of Wnt signaling in C. elegans

Robertson, S. M., & Lin, R. (2012) · Worm · doi:10.4161/worm.19156 · Cited by 6

Analysis of Wnt Signaling During Caenorhabditis elegans Postembryonic Development

Hoffelen, S. J. V., & Herman, M. A. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-469-2_8 · Cited by 6

EFL-3/E2F7 modulates Wnt signalling by repressing the Nemo-like kinase LIT-1 during asymmetric epidermal cell division in Caenorhabditis elegans

Ferrando-Marco, M., & Barkoulas, M. (2025) · Development · doi:10.1242/dev.204546 · Cited by 2

MEL-47, a novel protein required for early cell divisions in the nematode Caenorhabditis elegans

Minasaki, R., & Streit, A. (2006) · Molecular Genetics and Genomics · doi:10.1007/s00438-006-0191-z · Cited by 5

pop-1/TCF, ref-2/ZIC and T-box factors regulate the development of anterior cells in the C. elegans embryo

Rumley, J. D., Preston, E. A., Cook, D., Peng, F., Zacharias, A. L., Wu, L., Jileaeva, I., & Murray, J. I. (2022) · Developmental Biology · doi:10.1016/j.ydbio.2022.05.019 · Cited by 4

Wnt signaling in C. elegans: New insights into the regulation of POP‐1/ TCF‐mediated activation and repression

Korswagen, H. C. (2007) · Advances in developmental biology · doi:10.1016/s1574-3349(06)17003-9 · Cited by 4

Function of the Ryk intracellular domain in C. elegans vulval development

Poh, W. C., Yanqing, S., & Inoue, T. (2014) · Developmental Dynamics · doi:10.1002/dvdy.24159 · Cited by 3

RNT‐1 regulation in C. elegans

Ji, Y. J., Singaravelu, G., & Ahnn, J. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20423 · Cited by 3

PAR-5is a PARty hub in the germline

Aristizábal-Corrales, D., Schwartz, S., & Cerón, J. (2013) · Worm · doi:10.4161/worm.21834 · Cited by 3

Inductive asymmetric cell division

Ishidate, T., Kim, S. Y., Mello, C. C., & Shirayama, M. (2013) · Worm · doi:10.4161/worm.26276 · Cited by 3

Cell Polarity and Asymmetric Cell Division by the Wnt Morphogen

Baldwin, A. T., & Phillips, B. T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802438-6.00003-6 · Cited by 3

Reciprocal signaling by Wnt and Notch specifies a muscle precursor in the C. elegans embryo

Robertson, S. M., Medina, J., Oldenbroek, M., & Lin, R. (2017) · Development · doi:10.1242/dev.145391 · Cited by 2

Transcriptional feedback targeting Wnt pathway components reveals hidden heterogeneity in Caenorhabditis elegans seam cell lineages

Ferrando-Marco, M., Berger, S., & Barkoulas, M. (2026) · Genetics · doi:10.1093/genetics/iyag147 · Cited by 1

Nuclear localization and transactivation of SYS-1/β-catenin is the result of serial gene duplications and subfunctionalizations

Wolf, A. K.-L., Adams-Phillips, L. C., Adams, A. N. D., Erives, A. J., & Phillips, B. T. (2021) · Cells and Development · doi:10.1016/j.cdev.2025.204013 · Cited by 1

Cell Polarity in One-Cell C. elegans Embryos: Ensuring an Accurate and Precise Spatial Axis During Development

Mikl, M., & Cowan, C. R. (2015) · Springer eBooks · doi:10.1007/978-3-319-14466-5_1 · Cited by 1

Characterizing the role of C. elegans dsh-2 in asymmetric cell division and embryonic development

Lee, S. C.-H. (2005) · Summit (Simon Fraser University) · Cited by 1

CHARACTERIZATION OF HAM-1 IN THE ASYMMETRIC DIVISION OF C. ELEGANS NEUROBLASTS

Leung, A. (2007) · Summit (Simon Fraser University)

A NOVEL NON-CANONICAL WNT PATHWAY REGULATES THE ASYMMETRIC B CELL DIVISION IN CAENORHABDITIS ELEGANS

Wu, M. (2005) · K-State Research Exchange (Kansas State University)

Genomes & Developmental Control The Wnt effector POP-1 and the PAL-1/Caudal homeoprotein collaborate with SKN-1 to activate C. elegans endoderm development

Maduro, M., Kasmir, J. J., Zhu, J., & Rothman, J. H. (2005)

Wnt/β-catenin Pathway Functions by Inactivation of Tcf7l1 Protein

Wu, C.-S. P. (2014) · Figshare

Genomes & Developmental Control Genetic redundancy in endoderm specification within the genus Caenorhabditis

Maduro, M., Hill, R. J., Heid, P. J., Newman-Smith, E. D., Zhu, J., Priess, J. R., & Rothman, J. H. (2005)

gob-1 is a trehalose-6-phosphate phosphatase required for intestine development in the nematode caenorhabditis elegans

Kormish, J. D. (2004) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/11628

14-3-3 sigma interacts with liver X receptor beta

Jackson, E. A. (2010) · Louisiana State University · doi:10.31390/gradschool_theses.4251

EFL-3/E2F7 modulates Wnt signalling through repressing the LIT-1 Nemo-like kinase during asymmetric epidermal cell division in Caenorhabditis elegansPreprint

Ferrando-Marco, M., & Barkoulas, M. (2024) · bioRxiv · doi:10.1101/2024.07.01.601538

SYS-1/beta-catenin inheritance and regulation by Wnt signaling during asymmetric cell division

Michel, M. F. V., & Phillips, B. T. (2025) · Molecular Biology of the Cell · doi:10.1091/mbc.e24-10-0441

Regulation of hlh-2 transcription during specification of the anchor cell of the C. elegans hermaphrodite gonad

Kim, J. H., & Greenwald, I. (2025) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkaf288

Investigation of PHR Signaling in C. elegans

Tulgren, E. D. (2013) · University of Minnesota Digital Conservancy (University of Minnesota)

Transcriptional feedback targeting Wnt pathway components reveals hidden heterogeneity in C. elegans seam cell lineagesPreprint

Ferrando-Marco, M., Berger, S., & Barkoulas, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.04.709659

Role of Wnt signaling in the polarization of neuronal precursors in the C. elegans embryo

Kaur, S. (2018) · theses.fr (ABES) · doi:10.70675/2f0f57b8z5525z48a8z9c69z90d6e94c149b

Caractérisation du trafic cellulaire du canal potassique à deux domaines P UNC-58 par la protéine UNC-44 chez le nématode C. elegans

Tardy, P. (2018) · theses.fr (ABES) · doi:10.70675/8c9f600cz0627z4dcdz9142z731f52dc009c

Frizzled distribution and dynamics as response to Wnt signals : an in vitro approach using C. elegans embryonic cells

Pai, P. (2022) · theses.fr (ABES) · doi:10.70675/70c5e96dz5e1ez48a9za3bezbb9c70c30d06

MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans

Meneghini, M. D., Ishitani, T., Carter, J. C., Hisamoto, N., Ninomiya-Tsuji, J., Thorpe, C. J., Hamill, D. R., Matsumoto, K., & Bowerman, B. (1999) · Nature · doi:10.1038/21666 · Cited by 293

NLK TAKs onto the Wnt signalling pathway

Townsley, F. M. (1999) · Trends in Cell Biology · doi:10.1016/s0962-8924(99)01654-2 · Cited by 1

Distinct and mutually inhibitory binding by two divergent β-catenins coordinates TCF levels and activity inC. elegans

Yang, X., Huang, S., Lo, M., Mizumoto, K., Sawa, H., Xu, W., Robertson, S. M., & Lin, R. (2011) · Development · doi:10.1242/dev.069054 · Cited by 28

Functional analyses of vertebrate TCF proteins in C. elegans embryos

Robertson, S. M., Lo, M., Odom, R. S., Yang, X., Medina, J., Huang, S., & Lin, R. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.04.012 · Cited by 6

A β-Catenin Identified by Functional Rather Than Sequence Criteria and Its Role in Wnt/MAPK Signaling

Kidd, A. R., Miskowski, J. A., Siegfried, K. R., Sawa, H., & Kimble, J. E. (2005) · Cell · doi:10.1016/j.cell.2005.03.029 · Cited by 144