DIABETES MELLITUS
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These findings suggested that differences in glucose gradients may be related to forearm muscle resistance to insulin action and that diabetes could be separated into distinct subgroups-insulin insufficiency and insulin insensitivity.
“These findings suggested that differences in glucose gradients may be related to forearm muscle resistance to insulin action and that those with diabetes could be separated into distinct subgroups—the first with disease resulting from insulin insufficiency and the second with disease occurring due to insulin insensitivity23.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [23]
Direct comparison of forearm arteriovenous glucose gradients after simultaneous glucose and insulin administration showed differences in lean, young patients with diabetes compared to older, overweight patients.
“Direct comparison of forearm arteriovenous glucose gradients after simultaneous glucose and insulin administration showed differences in lean, young patients with diabetes compared to older, overweight patients23.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [23]
Cited by
Sorted by citations
Inflammatory Mechanisms in Obesity
Gregor, M. F., & Hotamisligil, G. S. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101322 · Cited by 3,754 · see citing works
Mechanisms of Insulin Action and Insulin Resistance
Petersen, M. C., & Shulman, G. I. (2018) · Physiological Reviews · doi:10.1152/physrev.00063.2017 · Cited by 3,028 · see citing works
Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
Kahn, S. E., Cooper, M. E., & Del Prato, S. (2014) · The Lancet · doi:10.1016/s0140-6736(13)62154-6 · Cited by 1,743 · see citing works
Body temperature regulation in diabetes
Kenny, G. P., Sigal, R. J., & McGinn, R. (2016) · Temperature · doi:10.1080/23328940.2015.1131506 · Cited by 297 · see citing works
100 years of insulin: celebrating the past, present and future of diabetes therapy
Sims, E. K., Carr, A. L. J., Oram, R. A., DiMeglio, L. A., & Evans-Molina, C. (2021) · Nature Medicine · doi:10.1038/s41591-021-01418-2 · Cited by 270 · see citing works
Clausen, J. O., Borch-Johnsen, K., Ibsen, H., Bergman, R. N., Hougaard, P., Winther, K., & Pedersen, O. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118903 · Cited by 259 · see citing works
Insulin resistance and coronary heart disease in nondiabetic individuals
Reaven, G. (2012) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.111.241885 · Cited by 227 · see citing works
Hunter, S. J., & Garvey, W. T. (1998) · The American Journal of Medicine · doi:10.1016/s0002-9343(98)00300-3 · Cited by 200 · see citing works
Modan, M., Karasik, A., Halkin, H., Fuchs, Z., Lusky, A., Shitrit, A., & Modan, B. (1986) · Diabetologia · doi:10.1007/bf00456115 · Cited by 161 · see citing works
Plasma glucose and insulin response to macronutrients in nondiabetic and NIDDM subjects
Nuttall, F. Q., & Gannon, M. C. (1991) · Diabetes Care · doi:10.2337/diacare.14.9.824 · Cited by 152 · see citing works
A Synopsis of the Associations of Oxidative Stress, ROS, and Antioxidants with Diabetes Mellitus
Black, H. S. (2022) · Antioxidants · doi:10.3390/antiox11102003 · Cited by 103 · see citing works
β-Cell failure in type 2 diabetes
Leibowitz, G., Kaiser, N., & Cerasi, E. (2011) · Journal of Diabetes Investigation · doi:10.1111/j.2040-1124.2010.00094.x · Cited by 78 · see citing works
The Peripheral Peril: Injected Insulin Induces Insulin Insensitivity in Type 1 Diabetes
Gregory, J. M., Cherrington, A. D., & Moore, D. J. (2020) · Diabetes · doi:10.2337/dbi19-0026 · Cited by 76 · see citing works
Gale, E. A. M. (2006) · Diabetologia · doi:10.1007/s00125-006-0348-7 · Cited by 71 · see citing works
Insulin Regulation of Hepatic Lipid Homeostasis
Uehara, K., Santoleri, D., Whitlock, A. E. G., & Titchenell, P. M. (2023) · Comprehensive Physiology · doi:10.1002/cphy.c220015 · Cited by 49 · see citing works
- Authors
- Himsworth, H. P.
- Corresponding author
- Himsworth, H.P.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1936-01
- Volume
- 227
- Issue
- 5864
- Pages
- 127-130
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2166142060
- Cited by
- 441
- References
- 0
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 8 · 2023: 15 · 2022: 9 · 2021: 15 · 2020: 12 · 2019: 12 · 2018: 7 · 2017: 10 · 2016: 16 · 2015: 14 · 2014: 15 · 2013: 22 · 2012: 17
- FWCI
- 17.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- diabetes mellitus, insulin sensitivity, insulin resistance, insulin action, blood glucose, hyperglycemia, glucose tolerance test, pancreatic insulin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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