Cited by 2,819Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesFamily and Disability Support Research

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Autism spectrum disorder

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Lord, Catherine, Elsabbagh, Mayada, Baird, Gillian, Veenstra-Vanderweele, Jeremy·2018·The Lancet

DOI 10.1016/s0140-6736(18)31129-2PMC PMC7398158

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Abstract

Autism spectrum disorder is a term used to describe a constellation of early-appearing social communication deficits and repetitive sensory-motor behaviours associated with a strong genetic component as well as other causes. The outlook for many individuals with autism spectrum disorder today is brighter than it was 50 years ago; more people with the condition are able to speak, read, and live in the community rather than in institutions, and some will be largely free from symptoms of the disorder by adulthood. Nevertheless, most individuals will not work full-time or live independently. Genetics and neuroscience have identified intriguing patterns of risk, but without much practical benefit yet. Considerable work is still needed to understand how and when behavioural and medical treatments can be effective, and for which children, including those with substantial comorbidities. It is also important to implement what we already know and develop services for adults with autism spectrum disorder. Clinicians can make a difference by providing timely and individualised help to families navigating referrals and access to community support systems, by providing accurate information despite often unfiltered media input, and by anticipating transitions such as family changes and school entry and leaving.

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Authors: Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J.
Affiliations: NewYork–Presbyterian Hospital (US)
McGill University (CA)
Kings Health Partners (GB)
Corresponding author: Lord, Catherine
ORCID: Lord, Catherine
Elsabbagh, Mayada
Baird, Gillian
Veenstra-Vanderweele, Jeremy
Venue: The Lancet
Publisher: Elsevier BV
Published: 2018-08
Volume: 392
Issue: 10146
Pages: 508-520
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(18)31129-2
PMC: PMC7398158
OpenAlex: W2886989735
Cited by: 2,819
References: 137
Citations by year: 2026: 559 · 2025: 492 · 2024: 420 · 2023: 403 · 2022: 333 · 2021: 285 · 2020: 192 · 2019: 83 · 2018: 24
FWCI: 19.49
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
Weill Cornell Medical College
Health Canada
Fonds de Recherche du Québec - Santé
National Institute of Mental Health (R01MH104423)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD081199)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
Keywords: autism spectrum disorder, social communication deficits, genetic risk factors, comorbidities, coming of age, community support services, family support, media misinformation
MeSH terms: Autism Spectrum Disorder, Adolescent, Adult, Child, Humans, Risk Factors

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