Transferrin and transferrin receptors in carcinoma of the breast

Host antigens in schistosomiasis

Smithers, S. R., Terry, R. J., & HOCKLEY, D. J. (1969) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1969.0007 · Cited by 281 · see citing works

Glutaradehyde-activated aminohexyl-derivative of sepharose 4B as a new versatile immunoabsorbent

Cambiaso, C. L., Goffinet, A., Vaerman, J. P., & Heremans, J. F. (1975) · Immunochemistry · doi:10.1016/0019-2791(75)90175-5 · Cited by 217 · see citing works

Isoantigenic expression of Forssman glycolipid in human gastric and colonic mucosa: Its possible identity with “A-like antigen” in human cancer

Hakomori, S., Wang, S.-M., & Young, W. W. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.7.3023 · Cited by 181 · see citing works

Antigens of human trophoblasts: A working hypothesis for their role in normal and abnormal pregnancies

Faulk, W. P., Temple, A., Lovins, R. E., & SMITH, N. C. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.4.1947 · Cited by 178 · see citing works

Transferrin receptor in human placental brush border membranes. Studies on the binding of transferrin to placental membrane vesicles and the identification of a placental brush border glycoprotein with high affinity for transferrin.

Wada, H., Hass, P. E., & Sussman, H. H. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86360-3 · Cited by 174 · see citing works

Immunological studies of human placentae: identification and distribution of proteins in mature chorionic villi.

Faulk, W. P., & Johnson, P. (1977) · PubMed · Cited by 134 · see citing works

Transferrin binding by human lymphoblastoid cell lines and other transformed cells

Galbraith, G. M. P., Galbraith, R. M., & Faulk, W. P. (1980) · Cellular Immunology · doi:10.1016/0008-8749(80)90072-6 · Cited by 100 · see citing works

Recent Developments in Immunofluorescence

Faulk, W. P., & Hijmans, W. (2015) · Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy · doi:10.1159/000393067 · Cited by 86 · see citing works

Trophoblast transferrin and transferrin receptors in the host–parasite relationship of human pregnancy

Faulk, W. P., & Galbraith, G. M. P. (1979) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1979.0014 · Cited by 81 · see citing works

Immunological studies of human placentae: identification and distribution of proteins in immature chorionic villi.

Johnson, P., & Faulk, W. P. (1978) · PubMed · Cited by 69 · see citing works

Transferrin Receptor in Human Placental Brush Border Membranes

Wada, H., Hass, P. E., & Sussmang, H. H. (1979) · Cited by 67 · see citing works

Transferrin receptors on the human placental microvillous membrane.

Loh, T. T., Higuchi, D. A., van BOCKXMEER, F. M., Smith, C. H., & Brown, E. B. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109773 · Cited by 64 · see citing works

Immunological studies of transferrin and transferrin receptors of human placental trophoblast

Galbraith, G. M. P., Galbraith, R. M., & Faulk, W. P. (1980) · Placenta · doi:10.1016/s0143-4004(80)80014-2 · Cited by 58 · see citing works

Trophoblast modulation of maternal allogeneic recognition.

McIntyre, J. A., & Faulk, W. P. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.8.4029 · Cited by 53 · see citing works

A Method for the Use of Immunofluorescence on Paraffin-embedded Tissues

Dorsett, B. H., & Ioachim, H. L. (1978) · American Journal of Clinical Pathology · doi:10.1093/ajcp/69.1.66 · Cited by 50 · see citing works

Transferrin and iron uptake by human cells in culture

Hemmaplardh, D., & MORGAN, E. (1974) · Experimental Cell Research · doi:10.1016/0014-4827(74)90543-6 · Cited by 47 · see citing works

Recent Developments in Immunofluorescence (with colour plates I and II)

Faulk, P., & Hijmans, W. (1972) · Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy · doi:10.1159/000313167 · Cited by 34 · see citing works

Blood group and tissue genetic markers in familial adenocarcinoma: potential specific immunotherapy.

Levine, P. (1978) · PubMed · Cited by 21 · see citing works

Ferritin for the clinician

Knovich, M. A., Storey, J. A., Coffman, L. G., Torti, S. V., & Torti, F. M. (2008) · Blood Reviews · doi:10.1016/j.blre.2008.08.001 · Cited by 666 · see citing works

Mitochondria regulation in ferroptosis

Wang, H., Liu, C., Zhao, Y., & Gao, G. (2019) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2019.151058 · Cited by 655 · see citing works

The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer

Daniels‐Wells, T. R., Delgado, T., Rodríguez, J. A., Helguera, G. F., & Penichet, M. L. (2006) · Clinical Immunology · doi:10.1016/j.clim.2006.06.010 · Cited by 630 · see citing works

Transferrin receptors in human tissues: their distribution and possible clinical relevance.

Gatter, K. C., Brown, G., Trowbridge, I. S., Woolston, R.-E., & Mason, D. Y. (1983) · Journal of Clinical Pathology · doi:10.1136/jcp.36.5.539 · Cited by 530 · see citing works

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors

Laske, D. W., Youle, R. J., & Oldfield, E. H. (1997) · Nature Medicine · doi:10.1038/nm1297-1362 · Cited by 525 · see citing works

Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis

Pinnix, Z. K., Miller, L. D., Wang, W., D’Agostino, R., Kute, T., Willingham, M. C., Hatcher, H., Tesfay, L., Sui, G., Di, X., et al. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3001127 · Cited by 448 · see citing works

Convection-Enhanced Delivery

Mehta, A. M., Sonabend, A. M., & Bruce, J. N. (2017) · Neurotherapeutics · doi:10.1007/s13311-017-0520-4 · Cited by 343 · see citing works

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

Cotten, M. L., Längle-Rouault, F., Kirlappos, H., Wagner, E., Mechtler, K., Zenke, M., Beug, H., & Birnstiel, M. L. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.11.4033 · Cited by 337 · see citing works

Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro.

Trowbridge, I. S., & Lopez, F. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.4.1175 · Cited by 328 · see citing works

Transferrin Receptor-Mediated Endocytosis: A Useful Target for Cancer Therapy

Tortorella, S. M., & Karagiannis, T. C. (2014) · The Journal of Membrane Biology · doi:10.1007/s00232-014-9637-0 · Cited by 316 · see citing works

Biosynthesis of the human transferrin receptor in cultured cells.

Omary, M. B., & Trowbridge, I. S. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42979-1 · Cited by 306 · see citing works

Transferrin Receptor Ligand-Targeted Toxin Conjugate (Tf-CRM107) for Therapy of Malignant Gliomas

Weaver, M. W., & Laske, D. W. (2003) · Journal of Neuro-Oncology · doi:10.1023/a:1026246500788 · Cited by 299 · see citing works

Iron as a central player and promising target in cancer progression

Jung, M., Mertens, C., Tomat, E., & Brüne, B. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20020273 · Cited by 268 · see citing works

Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells

Trowbridge, I. S., & Domingo, D. L. (1981) · Nature · doi:10.1038/294171a0 · Cited by 275 · see citing works

Anthracyclines/trastuzumab: new aspects of cardiotoxicity and molecular mechanisms

Rochette, L., Guénancia, C., Gudjoncik, A., Hachet, O., Zeller, M., Cottin, Y., & Vergely, C. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.03.005 · Cited by 251 · see citing works

Intracellular targeting therapy of cisplatin‐encapsulated transferrin‐polyethylene glycol liposome on peritoneal dissemination of gastric cancer

Iinuma, H., Maruyama, K., Okinaga, K., Sasaki, K., Sekine, T., Ishida, O., Ogiwara, N., Johkura, K., & Yonemura, Y. (2002) · International Journal of Cancer · doi:10.1002/ijc.10242 · Cited by 216 · see citing works

An iron regulatory gene signature predicts outcome in breast cancer

Miller, L. D., Coffman, L. G., Chou, J. W., Black, M. A., Bergh, J., D'Agostino, R., Torti, S. V., & Torti, F. M. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1870 · Cited by 202 · see citing works

Heme, Heme Oxygenase, and Ferritin: How the Vascular Endothelium Survives (and Dies) in an Iron-Rich Environment

Balla, J., Vercellotti, G. M., Jeney, V., Yachie, A., Varga, Z., Jacob, H. S., Eaton, J. W., & Balla, G. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1787 · Cited by 212 · see citing works

Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends

Choudhury, H., Pandey, M., Chin, P. X., Phang, Y. L., Cheah, J. Y., Ooi, S. C., Mak, K., Pichika, M. R., Kesharwani, P., Hussain, Z., et al. (2018) · Drug Delivery and Translational Research · doi:10.1007/s13346-018-0552-2 · Cited by 210 · see citing works

Targeting ferroptosis in breast cancer

Li, Z., Chen, L., Chen, C., Zhou, Y., Hu, D., Yang, J., Chen, Y., Zhuo, W., Mao, M., Zhang, X., et al. (2020) · Biomarker Research · doi:10.1186/s40364-020-00230-3 · Cited by 204 · see citing works

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

Callens, C., Coulon, S., Naudin, J., Radford-Weiss, I., Boissel, N., Raffoux, E., Wang, P. H. M., Agarwal, S., Tamouza, H., Paubelle, E., et al. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20091488 · Cited by 197 · see citing works

CORRELATION OF TRANSFERRIN RECEPTOR EXPRESSION WITH HISTOLOGICAL CLASS AND OUTCOME IN NON-HODGKIN LYMPHOMA

Habeshaw, J. A., Lister, T. A., Stansfeld, A. G., & Greaves, M. F. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92191-8 · Cited by 190 · see citing works

Transferrin receptor in normal and neoplastic brain tissue: implications for brain-tumor immunotherapy

Recht, L. D., Torres, C. O., Smith, T. W., Raso, V., & Griffin, T. W. (1990) · Journal of neurosurgery · doi:10.3171/jns.1990.72.6.0941 · Cited by 184 · see citing works

Mechanisms of TfR-mediated transcytosis and sorting in epithelial cells and applications toward drug delivery

Widera, A., Norouziyan, F., & Shen, W. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.07.004 · Cited by 173 · see citing works

Iron and Cancer: 2020 Vision

Torti, S. V., & Torti, F. M. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-2017 · Cited by 176 · see citing works

A Systems Biology Approach to Iron Metabolism

Chifman, J., Laubenbacher, R., & Torti, S. V. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-2095-2_10 · Cited by 175 · see citing works

Targeting of ultrasmall superparamagnetic iron oxide (USPIO) particles to tumor cells in Vivo by using transferrin receptor pathways

Kresse, M., Wagner, S., Pfefferer, D., Lawaczeck, R., Elste, V., & Semmler, W. (1998) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910400209 · Cited by 161 · see citing works

The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase IIα in Breast Cancer Cells

Rao, V. A., Klein, S. R., Agama, K., Toyoda, E., Adachi, N., Pommier, Y. G., & Shacter, E. B. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-1437 · Cited by 155 · see citing works

The Role of Iron in Cancer Progression

Guo, Q., Li, L., Hou, S., Yuan, Z., Li, C., Zhang, W., Zheng, L., & Li, X. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.778492 · Cited by 150 · see citing works

The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo

Kaptein, S. J. F., Efferth, T., Leis, M., Rechter, S., Auerochs, S., Kalmer, M., Bruggeman, C. A., Vink, C., Stamminger, T., & Marschall, M. (2005) · Antiviral Research · doi:10.1016/j.antiviral.2005.10.003 · Cited by 148 · see citing works

Does excess iron play a role in breast carcinogenesis? an unresolved hypothesis

Kabat, G. C., & Rohan, T. E. (2007) · Cancer Causes & Control · doi:10.1007/s10552-007-9058-9 · Cited by 148 · see citing works

Transferrin-conjugated lipid-coated PLGA nanoparticles for targeted delivery of aromatase inhibitor 7α-APTADD to breast cancer cells

Zheng, Y., Yu, B., Weecharangsan, W., Piao, L., Darby, M. V., Mao, Y., Koynova, R. D., Yang, X., Li, H., Xu, S., et al. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.02.008 · Cited by 133 · see citing works

Studies of the Transferrin Receptor on both Human Reticulocytes and Nucleated Human Cells in Culture

Frazier, J. L., Caskey, J. H., Yoffe, M., & Seligman, P. A. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110525 · Cited by 131 · see citing works

Murine cell surface transferrin receptor: Studies with an anti‐receptor monoclonal antibody

Trowbridge, I. S., Lesley, J., & Schulte, R. J. (1982) · Journal of Cellular Physiology · doi:10.1002/jcp.1041120314 · Cited by 130 · see citing works

Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer

Prutki, M., Poljak‐Blaži, M., Jakopović, M., Tomas, D., Stipančić, I., & Žarković, N. (2005) · Cancer Letters · doi:10.1016/j.canlet.2005.07.001 · Cited by 129 · see citing works

Heme, heme oxygenase and ferritin in vascular endothelial cell injury

Balla, J., Vercellotti, G. M., Jeney, V., Yachie, A., Varga, Z., Eaton, J. W., & Balla, G. (2005) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200500076 · Cited by 123 · see citing works

Altered iron metabolism, inflammation, transferrin receptors, and ferritin expression in non-small-cell lung cancer

Kukulj, S., Jaganjac, M., Boranić, M., Križanac, Š., Šantić, Ž., & Poljak‐Blaži, M. (2009) · Medical Oncology · doi:10.1007/s12032-009-9203-2 · Cited by 121 · see citing works

Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy

Anabousi, S., Laue, M. M., Lehr, C., Bakowsky, U., & Ehrhardt, C. (2005) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.12.009 · Cited by 115 · see citing works

Differences in transferrin response and numbers of transferrin receptors in rat and human mammary carcinoma lines of different metastatic potentials

Inoue, T., Cavanaugh, P. G., Steck, P. A., Brünner, N., & Nicolson, G. L. (1993) · Journal of Cellular Physiology · doi:10.1002/jcp.1041560128 · Cited by 115 · see citing works

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients

Moura, I. C. (2004) · Blood · doi:10.1182/blood-2003-07-2440 · Cited by 114 · see citing works

Cellular Iron Metabolism in Health and Diseased

Weinberg, E. D. (1990) · Drug Metabolism Reviews · doi:10.3109/03602539008991450 · Cited by 112 · see citing works

Iron homeostasis in breast cancer

Marques, O., da Silva, B. M., Porto, G., & Lopes, C. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.01.029 · Cited by 115 · see citing works

Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice

Laske, D. W., Ilercil, O., Akbaşak, A., Youle, R. J., & Oldfield, E. H. (1994) · Journal of neurosurgery · doi:10.3171/jns.1994.80.3.0520 · Cited by 110 · see citing works

Dysregulation of iron metabolism in cancer stem cells

Recalcati, S., Gammella, E., & Cairo, G. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.07.015 · Cited by 107 · see citing works

Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells

Sadava, D., Phillips, T., Lin, C., & Kane, S. E. (2002) · Cancer Letters · doi:10.1016/s0304-3835(02)00005-8 · Cited by 100 · see citing works

Breast Carcinoma and the Role of Iron Metabolism

Elliott, R. L., Elliott, M. C., Wang, F., & Head, J. F. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb17204.x · Cited by 99 · see citing works

Lactoferrin and Cancer Disease Prevention

Rodrigues, L. R., Teixeira, J. A., Schmitt, F. C., Paulsson, M. A., & Månsson, H. L. (2008) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390701856157 · Cited by 96 · see citing works

Cellular Iron Metabolism in Prognosis and Therapy of Breast Cancer

Torti, S. V., & Torti, F. M. (2013) · Critical Reviews™ in Oncogenesis · doi:10.1615/critrevoncog.2013007784 · Cited by 93 · see citing works

Iron Chelators Inhibit the Growth and Induce the Apoptosis of Kaposi's Sarcoma Cells and of their Putative Endothelial Precursors

Simonart, T., Heenen, M., Degraef, C., Andreï, G., Mosselmans, R., Hermans, P., Vooren, J. V., Noël, J., Boelaert, J. R., & Snoeck, R. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00119.x · Cited by 92 · see citing works

Physical characterization of the transferrin receptor in human placentae.

Enns, C. A., & Sussman, H. H. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)68700-4 · Cited by 88 · see citing works

Intraventricular Immunotoxin Therapy for Leptomeningeal Neoplasia

Laske, D. W., Muraszko, K. M., Oldfield, E. H., DeVroom, H. L., Sung, C., Dedrick, R. L., Simon, T. R., Colandrea, J., Copeland, C., Katz, D., et al. (1997) · Neurosurgery · doi:10.1097/00006123-199711000-00005 · Cited by 87 · see citing works

p53-independent apoptosis mediated by tachpyridine, an anti-cancer iron chelator

Abeysinghe, R. D. (2001) · Carcinogenesis · doi:10.1093/carcin/22.10.1607 · Cited by 83 · see citing works

Transferrin Receptor Expression in Adenocarcinoma of the Lung as a Histopathologic Indicator of Prognosis

Kondo, K., Noguchi, M., Mukai, K., Matsuno, Y., Sato, Y., Shimosato, Y., & Monden, Y. (1990) · CHEST Journal · doi:10.1378/chest.97.6.1367 · Cited by 82 · see citing works

An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells

Ng, P. P., Cruz, J. S. D., Sorour, D. N., Stinebaugh, J. M., Shin, S.-U., Shin, D. S., Morrison, S. L., & Penichet, M. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162362999 · Cited by 81 · see citing works

Potent and specific killing of human malignant brain tumor cells by an anti-transferrin receptor antibody-ricin immunotoxin

Zovickian, J. G., Johnson, V. G., & Youle, R. J. (1987) · Journal of neurosurgery · doi:10.3171/jns.1987.66.6.0850 · Cited by 80 · see citing works

Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation

Turner, J. (2005) · Blood · doi:10.1182/blood-2005-03-1263 · Cited by 76 · see citing works

Selective stimulation of prostatic carcinoma cell proliferation by transferrin.

Rossi, M. C., & Zetter, B. R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.6197 · Cited by 77 · see citing works

Transferrin receptors and glioblastoma multiforme: Current findings and potential for treatment

Voth, B. L., Nagasawa, D. T., Pelargos, P. E., Chung, L. K., Ung, N. M., Gopen, Q. S., Tenn, S. E., Kamei, D. T., & Yang, I. (2015) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2015.02.002 · Cited by 76 · see citing works

Transferrin receptors of human fibroblasts. Analysis of receptor properties and regulation

Ward, J. H., Kushner, J. P., & Kaplan, J. (1982) · Biochemical Journal · doi:10.1042/bj2080019 · Cited by 75 · see citing works

Nitric Oxide Prevents Oxidative Damage Produced bytert-Butyl Hydroperoxide in Erythroleukemia Cells via Nitrosylation of Heme and Non-heme Iron

Gorbunov, N. V., Yalowich, J. C., Gaddam, A., Thampatty, P., Ritov, V. B., Kisin, E. R., Elsayed, N. M., & Kagan, V. E. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.19.12328 · Cited by 75 · see citing works

Distribution of ferritin, transferrin and lactoferrin in breast carcinoma tissue

Rossiello, R., Carriero, M. V., & Giordano, G. G. (1984) · Journal of Clinical Pathology · doi:10.1136/jcp.37.1.51 · Cited by 72 · see citing works

Transferrin conjugates of adriamycin are cytotoxic without intercalating nuclear DNA.

Barabás, K., SIZENSKY, J. A., & Faulk, W. P. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50442-2 · Cited by 71 · see citing works

Preparation, biodistribution, and small animal PET of 45Ti-transferrin.

Vāvere, A. L., & Welch, M. J. (2005) · PubMed · Cited by 70 · see citing works

Radioimmunochemical measurement of the transferrin receptor in human trophoblast and reticulocyte membranes with a specific anti-receptor antibody.

Enns, C. A., Shindelman, J. E., Tonik, S. E., & Sussman, H. H. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.7.4222 · Cited by 70 · see citing works

Tumor-Targeted and Clearable Human Protein-Based MRI Nanoprobes

Zhao, Y., Peng, J., Li, J., Huang, L. F., Yang, J., Huang, K., Li, H., Jiang, N., Zheng, S., Zhang, X., et al. (2017) · Nano Letters · doi:10.1021/acs.nanolett.7b00828 · Cited by 67 · see citing works

Antitumor effects of an immunotoxin made with Pseudomonas exotoxin in a nude mouse model of human ovarian cancer.

FitzGerald, D. J., Willingham, M. C., & PASTAN, I. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.17.6627 · Cited by 66 · see citing works

Hepcidin and its therapeutic potential in neurodegenerative disorders

Qian, Z., & Ke, Y. (2019) · Medicinal Research Reviews · doi:10.1002/med.21631 · Cited by 63 · see citing works

Effects of Transferrin Receptor Blockade on Cancer Cell Proliferation and Hypoxia-Inducible Factor Function and Their Differential Regulation by Ascorbate

Jones, D. T., Trowbridge, I. S., & Harris, A. L. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3857 · Cited by 75 · see citing works

Current understandings and clinical translation of nanomedicines for breast cancer therapy

Jiang, Y., Jiang, Z., Wang, M., & Ma, L. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114034 · Cited by 65 · see citing works

Intracellular chemiluminescence activates targeted photodynamic destruction of leukaemic cells

Laptev, R., Nisnevitch, M., Siboni, G., Malik, Z., & Firer, M. A. (2006) · British Journal of Cancer · doi:10.1038/sj.bjc.6603241 · Cited by 64 · see citing works

Transferrin receptor expression in non‐malignant and malignant human breast tissue

Walker, R. A., & Day, S. J. (1986) · The Journal of Pathology · doi:10.1002/path.1711480305 · Cited by 64 · see citing works

Recent advances in adult T-cell leukemia therapy: focus on a new anti-transferrin receptor monoclonal antibody

Callens, C., Moura, I. C., Lepelletier, Y., Coulon, S., Renand, A., Dussiot, M., Ghez, D., Benhamou, M., Monteiro, R. C., Bazarbachi, A. A., et al. (2007) · Leukemia · doi:10.1038/sj.leu.2404958 · Cited by 62 · see citing works

Autoantibodies unmasked by redox reactions

McIntyre, J. A., Wagenknecht, D. R., & Faulk, W. P. (2005) · Journal of Autoimmunity · doi:10.1016/j.jaut.2005.03.005 · Cited by 62 · see citing works

Antitumor activity of an immunotoxin in a nude mouse model of human ovarian cancer.

FitzGerald, D. J., Bjorn, M. J., Ferris, R. J., Winkelhake, J. L., Frankel, A. E., Hamilton, T. C., Ozols, R. F., Willingham, M. C., & Pastan, I. H. (1987) · PubMed · Cited by 62 · see citing works

Lipocalin-2 and iron trafficking in the tumor microenvironment

Jung, M., Mertens, C., Bauer, R., Rehwald, C., & Brüne, B. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.018 · Cited by 60 · see citing works

Transferrin Receptor Expression and the Control of Cell Growth

Neckers, L. Μ., & Trepel, J. B. (1986) · Cancer Investigation · doi:10.3109/07357908609017524 · Cited by 61 · see citing works

Antibody-Based Immunotoxins for the Treatment of Cancer

Becker, N., & Benhar, I. (2012) · Antibodies · doi:10.3390/antib1010039 · Cited by 61 · see citing works

Differential Expression of Transferrin Receptor (TfR) in a Spectrum of Normal to Malignant Breast Tissues

Singh, M., Mugler, K. C., Hailoo, D. W., Burke, S., Nemesure, B. B., Torkko, K. C., & Shroyer, K. R. (2011) · Applied immunohistochemistry & molecular morphology · doi:10.1097/pai.0b013e318209716e · Cited by 60 · see citing works

Up-regulation of vascular endothelial growth factor production by iron chelators.

Beerepoot, L. V., Shima, D. T., Kuroki, M., Yeo, K. T., & Voest, E. E. (1996) · PubMed · Cited by 60 · see citing works

Loss of transferrin receptors following induced differentiation of HL-60 promyelocytic leukemia cells

Yeh, C. G., Papamichael, M., & Faulk, W. P. (1982) · Experimental Cell Research · doi:10.1016/0014-4827(82)90192-6 · Cited by 60 · see citing works

Malarial parasites and tumour cells are killed by the same component of tumour necrosis serum.

Taverne, J., Matthews, N., Depledge, P., & Playfair, J. H. L. (1984) · PubMed Central · Cited by 60 · see citing works

Transferrin receptor and B-lymphoblast antigen — their relationship to DNA synthesis, histology and survival in B-cell lymphomas

Kvaløy, S., Langholm, R., Kaalhus, O., Michaelsen, T. E., Funderud, S., Abrahamsen, A. F., & Godal, T. (1984) · International Journal of Cancer · doi:10.1002/ijc.2910330204 · Cited by 58 · see citing works

Human amniochorion: Tissue-specific markers, transferrin receptors and histocompatibility antigens

Hsi, B., Yeh, C. G., & Faulk, W. P. (1982) · Placenta · doi:10.1016/s0143-4004(82)80012-x · Cited by 58 · see citing works

Iron homeostasis and anemia markers in early breast cancer

Lamy, P., Durigova, A., & Jacot, W. (2014) · Clinica Chimica Acta · doi:10.1016/j.cca.2014.04.011 · Cited by 57 · see citing works

Transferrin-Mediated Targeting of Bacteriophage HK97 Nanoparticles Into Tumor Cells

Huang, R. K., Steinmetz, N. F., Fu, C., Manchester, M., & Johnson, J. E. (2010) · Nanomedicine · doi:10.2217/nnm.10.99 · Cited by 57 · see citing works

Iron transport kinetics through blood-brain barrier endothelial cells

Khan, A. I., Liu, J., & Dutta, P. (2018) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2018.02.010 · Cited by 57 · see citing works

Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor

Ng, P. P., Helguera, G. F., Daniels‐Wells, T. R., Lomas, S. Z., Rodríguez, J. A., Schiller, G. J., Bonavida, B., Morrison, S. L., & Penichet, M. L. (2006) · Blood · doi:10.1182/blood-2006-04-020263 · Cited by 56 · see citing works

Targeting Receptors, Transporters and Site of Absorption to Improve Oral Drug Delivery

Hamman, J. H., Demana, P. H., & Olivier, E. I. (2007) · Drug Target Insights · doi:10.1177/117739280700200003 · Cited by 55 · see citing works

(C) Means to enhance penetration

Shen, W., Wan, J., & Ekrami, H. (1992) · Advanced Drug Delivery Reviews · doi:10.1016/0169-409x(92)90016-j · Cited by 55 · see citing works

Regulation of the hepatic transferrin receptor in hereditary hemochromatosis†

Lombard, M. G., Bomford, A. B., Hynes, M., Naoumov, N. V., Roberts, S., Crowe, J., & Williams, R. L. (1989) · Hepatology · doi:10.1002/hep.1840090102 · Cited by 54 · see citing works

In vivo gene delivery to tumor cells by transferrin‐streptavidin‐DNA conjugate

Sato, Y., Yamauchi, N., Takahashi, M., Sasaki, K., Fukaura, J., Neda, H., Fujii, S., Hirayama, M., Itoh, Y., Koshita, Y., et al. (2000) · The FASEB Journal · doi:10.1096/fj.99-1052com · Cited by 53 · see citing works

Selection and properties of a mouse L-cell transformant expressing human transferrin receptor

Newman, R., Domingo, D. L., Trotter, J., & Trowbridge, I. S. (1983) · Nature · doi:10.1038/304643a0 · Cited by 53 · see citing works

Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway

Cui, C., Cheng, X., Yan, L., Ding, H., Guan, X., Zhang, W., Tian, X., & Hao, C. (2019) · Cancer Management and Research · doi:10.2147/cmar.s198911 · Cited by 51 · see citing works

In vitro efficacy of transferrin-toxin conjugates against glioblastoma multiforme

Hall, W. A., Godál, A., Juell, S., & Fodstad, Ø. (1992) · Journal of neurosurgery · doi:10.3171/jns.1992.76.5.0838 · Cited by 50 · see citing works

Similarities between the transferrin receptor proteins on human reticulocytes and human placentae.

Enns, C. A., & Sussman, H. H. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42934-1 · Cited by 50 · see citing works

Color Doppler Ultrasound and Gamma Imaging of Intratumorally Injected 500 nm Iron–Silica Nanoshells

Liberman, A., Wu, Z. B., Barback, C. V., Viveros, R. D., Blair, S. L., Ellies, L. G., Vera, D. R., Mattrey, R. F., Kummel, A. C., & Trogler, W. C. (2013) · ACS Nano · doi:10.1021/nn402507d · Cited by 48 · see citing works

Distribution of the transferrin receptor in normal human fibroblasts and fibrosarcoma cells

Ekblom, P., Thesleff, I., Lehto, V., & Virtanen, I. (1983) · International Journal of Cancer · doi:10.1002/ijc.2910310118 · Cited by 48 · see citing works

Upregulation of transferrin receptor-1 induces cholangiocarcinoma progression via induction of labile iron pool

Jamnongkan, W., Thanan, R., Techasen, A., Namwat, N., Loilome, W., Intarawichian, P., Titapun, A., & Yongvanit, P. (2017) · Tumor Biology · doi:10.1177/1010428317717655 · Cited by 47 · see citing works

Isolation, Characterization and Bioactivities of an Extracellular Polysaccharide Produced from Streptomyces sp. MOE6

Elnahas, M. O., Amin, M. A., Hussein, M., Shanbhag, V., Ali, A. E., & Wall, J. D. (2017) · Molecules · doi:10.3390/molecules22091396 · Cited by 47 · see citing works

Transferrin receptor-1 and VEGF are prognostic factors for osteosarcoma

Wu, H., Zhang, J., Dai, R., Xu, J., & Feng, H. (2019) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-019-1301-z · Cited by 47 · see citing works

The expression of tnf receptors at the materno/fetal interface in normal human pregnancy

Vince, G. (1991) · Placenta · doi:10.1016/0143-4004(91)90482-u · Cited by 1 · see citing works

Transferrin receptor expression in non‐malignant and malignant human breast tissue

Walker, R. A., & Day, S. J. (1986) · The Journal of Pathology · doi:10.1002/path.1711480305 · Cited by 64 · see citing works

Demonstration of the transferrin receptor in human breast cancer tissue. Potential marker for identifying dividing cells

Shindelman, J. E., Ortmeyer, A. E., & Sussman, H. H. (1981) · International Journal of Cancer · doi:10.1002/ijc.2910270311 · Cited by 195 · see citing works

Serum Transferrin Receptor Level Is Not Altered in Invasive Adenocarcinoma of the Breast

Raaf, H. N., Jacobsen, D. W., Savon, S. R., & Green, R. (1993) · American Journal of Clinical Pathology · doi:10.1093/ajcp/99.3.232 · Cited by 25 · see citing works

Transferrin receptors in cultured breast cancer cells

Vandewalle, B., Granier, A., Peyrat, J. P., Bonneterre, J. M., & Lefèbvre, J. L. (1985) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/bf00402505 · Cited by 22 · see citing works