The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.
Functional somatic syndromes: one or many?
Abstract
We review the concept and importance of functional somatic symptoms and syndromes such as irritable bowel syndrome and chronic fatigue syndrome. On the basis of a literature review, we conclude that a substantial overlap exists between the individual syndromes and that the similarities between them outweigh the differences. Similarities are apparent in case definition, reported symptoms, and in non-symptom association such as patients' sex, outlook, and response to treatment. We conclude that the existing definitions of these syndromes in terms of specific symptoms is of limited value; instead we believe a dimensional classification is likely to be more productive.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In the healthcare system, patients frequently receive medical specialty-specific syndrome diagnoses (FSS) such as fibromyalgia, chronic widespread pain, chronic fatigue syndrome, and irritable bowel syndrome [6,7].”
From Internet-delivered treatment for patients suffering from severe functional somatic disorders: Protocol for a randomized controlled trial (2023) · cites this paper as [6]
Citations
Cites
The american college of rheumatology 1990 criteria for the classification of fibromyalgia
Wolfe, F., Smythe, H. A., Yunus, M. B., Bennett, R. M., Bombardier, C., Goldenberg, D. L., Tugwell, P., Campbell, S. M., Abeles, M., Clark, P., et al. (1990) · Arthritis & Rheumatism · doi:10.1002/art.1780330203 · Cited by 9,563
Drossman, D. A., Li, Z., Andruzzi, E., Temple, R. D., Talley, N. J., Grant Thompson, W., Whitehead, W. E., Janssens, J., Funch-Jensen, P., Corazziari, E., et al. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01303162 · Cited by 2,198
A report—Chronic fatigue syndrome: Guidelines for research
Sharpe, M. C. (1991) · Journal of the Royal Society of Medicine · doi:10.1177/014107689108400224 · Cited by 1,026
Self-citationBARSKY, A. J., & Borus, J. F. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-130-11-199906010-00016 · Cited by 964
The Development of a Menstrual Distress Questionnaire
Moos, R. (1968) · Psychosomatic Medicine · doi:10.1097/00006842-196811000-00006 · Cited by 941
Physical symptoms in primary care. Predictors of psychiatric disorders and functional impairment
Kroenke, K. (1994) · Archives of Family Medicine · doi:10.1001/archfami.3.9.774 · Cited by 741
Wolff’s Headache and Other Head Pain
(2009) · Archives of Neurology · doi:10.1001/archneurol.2009.17 · Cited by 588
Symptoms in the community. Prevalence, classification, and psychiatric comorbidity
Kroenke, K. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.153.21.2474 · Cited by 574
Cognitive behaviour therapy for the chronic fatigue syndrome: a randomised controlled trial.
Sharpe, M., Hawton, K., Simkin, S., Surawy, C., Hackmann, A., Klimes, I., Peto, T., Warrell, D., & Seagroatt, V. (1996) · BMJ · doi:10.1136/bmj.312.7022.22 · Cited by 528
Self-citationImipramine in Patients with Chest Pain Despite Normal Coronary Angiograms
Cannon, R. O., Quyyumi, A. A., Mincemoyer, R., Stine, A. M., Gracely, R. H., Smith, W. B., Geraci, M. F., Black, B. C., Uhde, T. W., Waclawiw, M. A., et al. (1994) · New England Journal of Medicine · doi:10.1056/nejm199405193302003 · Cited by 504
Research works printed but not linked: 15
- Deary, 1999, A taxonomy of medically unexplained symptoms, J Psychosom Res, 47, 51
- Gomborone, 1996, Prevalence of irritable bowel sydrome in chronic fatigue, J R Coll Physicians, 30, 512
- Maxton, 1989, Ranking of symptoms by patients with irritable bowel syndrome, BMJ, 299, 1138, 10.1136/bmj.299.6708.1138 · DOI
- Feinmann, 1984, Psychogenic facial pain. Part 1: the clinical presentation, Br Dent J, 156, 165, 10.1038/sj.bdj.4805298 · DOI
- Pearson, 1988, Psychologic and somatic interrelationships in allergy and pseudoallergy, J Allergy Clin Immunol, 81, 351, 10.1016/0091-6749(88)90900-1 · DOI
- Wearden, 1998, A double-blind, placebo controlled treatment trial of fluoxetine and a graded exercise programme for chronic fatigue syndrome, Br J Psychiatry, 172, 485, 10.1192/bjp.172.6.485 · DOI
- Natelson, 1996, Randomized, double-blind, controlled placebo-phase in trial of low dose phenelzine in the chronic fatigue syndrome, Psychopharmacology, 124, 226, 10.1007/BF02246661 · DOI
- Goldenberg, 1996, A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia, Arthritis Rheum, 39, 1852, 10.1002/art.1780391111 · DOI
- Carrette, 1986, Evaluation of amitriptyline in primary fibrositis: a double-blind placebo controlled study, Arthritis Rheum, 29, 655, 10.1002/art.1780290510 · DOI
- Norregaard, 1995, A randomized controlled trial of citalopram in the treatment of fibromyalgia, Pain, 61, 445, 10.1016/0304-3959(94)00218-4 · DOI
- Wolfe, 1994, A double-blind placebo controlled trial of fluoxetine in fibromyalgia, Scand J Rheumatol, 23, 255, 10.3109/03009749409103725 · DOI · Paper page
- Feinmann, 1984, Psychogenic facial pain: presentation and treatment, BMJ, 288, 436, 10.1136/bmj.288.6415.436 · DOI
- Cannon, 1994, Imipramine in patients with chest pain despite normal coronary arteries, N Engl J Med, 330, 1411, 10.1056/NEJM199405193302003 · DOI
- Steiner, 1996, Fluoxetine in the treatment of premenstrual dysphoria, N Engl J Med, 332, 1529, 10.1056/NEJM199506083322301 · DOI
- Yonkers, 1997, Symptomatic treatment of premenstrual dysphoric disorder with sertraline treatment: a randomized controlled trial, JAMA, 278, 983, 10.1001/jama.1997.03550120043031 · DOI
Cited by
Sorted by citations
Pharmacological interventions for somatoform disorders in adults
Kleinstäuber, M., Witthöft, M., Steffanowski, A., van Marwijk, H., Hiller, W., & Lambert, M. J. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010628.pub2 · Cited by 11,369
Carruthers, B. M., Jain, A. K., De Meirleir, K. L., Peterson, D. L., Klimas, N. G., Lerner, A. M., Bested, A. C., Flor-Henry, P., Joshi, P., Powles, A. C. P., et al. (2003) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v11n01_02 · Cited by 1,180
Whitehead, W. E., Palsson, O., & Jones, K. R. (2002) · Gastroenterology · doi:10.1053/gast.2002.32392 · Cited by 1,116
Prins, J. B., van der Meer, J. W., & Bleijenberg, G. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68073-2 · Cited by 974
Evidence of augmented central pain processing in idiopathic chronic low back pain
Giesecke, T., Gracely, R. H., Grant, M. A. B., NACHEMSON, A. L., Petzke, F. W., Williams, D. A., & Clauw, D. J. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20063 · Cited by 818
Metadata
- Authors
- Wessely, S., Nimnuan, C., & Sharpe, M.
- Affiliations
- Royal Edinburgh Hospital (GB)
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1999-09
- Volume
- 354
- Issue
- 9182
- Pages
- 936-939
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2137698397
- Cited by
- 1,211
- References
- 153
- Citations by year
- 2026: 20 · 2025: 29 · 2024: 36 · 2023: 26 · 2022: 24 · 2021: 36 · 2020: 37 · 2019: 36 · 2018: 36 · 2017: 53 · 2016: 38 · 2015: 53 · 2014: 36 · 2013: 38 · 2012: 49
- FWCI
- 5.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- functional somatic syndromes, irritable bowel syndrome, chronic fatigue syndrome, dimensional classification, case definition, symptom overlap, sex differences, treatment response
- MeSH terms
- Colonic Diseases, Functional, Combined Modality Therapy, Humans, Patient Care Team, Prognosis, Sick Role, Somatoform Disorders, Fatigue Syndrome, Chronic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
