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Cited by 1,211Psychosomatic Disorders and Their TreatmentsFibromyalgia and Chronic Fatigue Syndrome ResearchGastrointestinal motility and disorders

The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.

Functional somatic syndromes: one or many?

Wessely, S, Nimnuan, C, Sharpe, M·1999·The Lancet
DOI 10.1016/s0140-6736(98)08320-2
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Abstract

We review the concept and importance of functional somatic symptoms and syndromes such as irritable bowel syndrome and chronic fatigue syndrome. On the basis of a literature review, we conclude that a substantial overlap exists between the individual syndromes and that the similarities between them outweigh the differences. Similarities are apparent in case definition, reported symptoms, and in non-symptom association such as patients' sex, outlook, and response to treatment. We conclude that the existing definitions of these syndromes in terms of specific symptoms is of limited value; instead we believe a dimensional classification is likely to be more productive.

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Crossref · 10.1016/s0140-6736(98)08320-2

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Citations

Cites

Research works printed but not linked: 15

  1. Deary, 1999, A taxonomy of medically unexplained symptoms, J Psychosom Res, 47, 51
  2. Gomborone, 1996, Prevalence of irritable bowel sydrome in chronic fatigue, J R Coll Physicians, 30, 512
  3. Maxton, 1989, Ranking of symptoms by patients with irritable bowel syndrome, BMJ, 299, 1138, 10.1136/bmj.299.6708.1138 · DOI
  4. Feinmann, 1984, Psychogenic facial pain. Part 1: the clinical presentation, Br Dent J, 156, 165, 10.1038/sj.bdj.4805298 · DOI
  5. Pearson, 1988, Psychologic and somatic interrelationships in allergy and pseudoallergy, J Allergy Clin Immunol, 81, 351, 10.1016/0091-6749(88)90900-1 · DOI
  6. Wearden, 1998, A double-blind, placebo controlled treatment trial of fluoxetine and a graded exercise programme for chronic fatigue syndrome, Br J Psychiatry, 172, 485, 10.1192/bjp.172.6.485 · DOI
  7. Natelson, 1996, Randomized, double-blind, controlled placebo-phase in trial of low dose phenelzine in the chronic fatigue syndrome, Psychopharmacology, 124, 226, 10.1007/BF02246661 · DOI
  8. Goldenberg, 1996, A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia, Arthritis Rheum, 39, 1852, 10.1002/art.1780391111 · DOI
  9. Carrette, 1986, Evaluation of amitriptyline in primary fibrositis: a double-blind placebo controlled study, Arthritis Rheum, 29, 655, 10.1002/art.1780290510 · DOI
  10. Norregaard, 1995, A randomized controlled trial of citalopram in the treatment of fibromyalgia, Pain, 61, 445, 10.1016/0304-3959(94)00218-4 · DOI
  11. Wolfe, 1994, A double-blind placebo controlled trial of fluoxetine in fibromyalgia, Scand J Rheumatol, 23, 255, 10.3109/03009749409103725 · DOI · Paper page
  12. Feinmann, 1984, Psychogenic facial pain: presentation and treatment, BMJ, 288, 436, 10.1136/bmj.288.6415.436 · DOI
  13. Cannon, 1994, Imipramine in patients with chest pain despite normal coronary arteries, N Engl J Med, 330, 1411, 10.1056/NEJM199405193302003 · DOI
  14. Steiner, 1996, Fluoxetine in the treatment of premenstrual dysphoria, N Engl J Med, 332, 1529, 10.1056/NEJM199506083322301 · DOI
  15. Yonkers, 1997, Symptomatic treatment of premenstrual dysphoric disorder with sertraline treatment: a randomized controlled trial, JAMA, 278, 983, 10.1001/jama.1997.03550120043031 · DOI

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Metadata

Authors
Wessely, S., Nimnuan, C., & Sharpe, M.
Affiliations
Royal Edinburgh Hospital (GB)
ORCID
Venue
The Lancet
Publisher
Elsevier BV
Published
1999-09
Volume
354
Issue
9182
Pages
936-939
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/s0140-6736(98)08320-2
OpenAlex
W2137698397
Cited by
1,211
References
153
Citations by year
2026: 20 · 2025: 29 · 2024: 36 · 2023: 26 · 2022: 24 · 2021: 36 · 2020: 37 · 2019: 36 · 2018: 36 · 2017: 53 · 2016: 38 · 2015: 53 · 2014: 36 · 2013: 38 · 2012: 49
FWCI
5.33
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Keywords
functional somatic syndromes, irritable bowel syndrome, chronic fatigue syndrome, dimensional classification, case definition, symptom overlap, sex differences, treatment response
MeSH terms
Colonic Diseases, Functional, Combined Modality Therapy, Humans, Patient Care Team, Prognosis, Sick Role, Somatoform Disorders, Fatigue Syndrome, Chronic

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