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Relation of Leisure-Time Physical Activity and Cardiorespiratory Fitness to the Risk of Acute Myocardial Infarction in Men

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Inhibition of human aromatase by mammalian lignans and isoflavonoid phytoestrogens

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Dietary natural products as emerging lipoprotein(a)‐lowering agents

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Urinary excretion of lignans after administration of isolated plant lignans to rats: the effect of single dose and ten-day exposures

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Structure of Brewer’s Spent Grain Lignin and Its Interactions with Gut Microbiota in Vitro

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Phytoestrogens in foods

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Milk concentrations of the mammalian lignans enterolactone and enterodiol, milk production, and whole tract digestibility of dairy cows fed diets containing different concentrations of flaxseed meal

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Milk concentration of the mammalian lignan enterolactone, milk production, milk fatty acid profile, and digestibility in dairy cows fed diets containing whole flaxseed or flaxseed meal

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AAPH-mediated antioxidant reactions of secoisolariciresinol and SDG

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Treatment of Older Persons With Hypercholesterolemia With and Without Cardiovascular Disease

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A Semiquantitative Food Frequency Questionnaire Is a Valid Indicator of the Usual Intake of Phytoestrogens by South Asian Women in the UK Relative to Multiple 24-h Dietary Recalls and Multiple Plasma Samples

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Determination of plant and enterolignans in human serum by high-performance liquid chromatography with tandem mass spectrometric detection

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Liquid chromatographic–tandem mass spectrometric method for the plant lignan 7-hydroxymatairesinol and its potential metabolites in human plasma

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Suitability of a batch in vitro fermentation model using human faecal microbiota for prediction of conversion of flaxseed lignans to enterolactone with reference to an in vivo rat model

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Metabolism of flavonoids and lignans by lactobacilli and bifidobacteria strains improves the nutritional properties of flaxseed-enriched beverages

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Preventing diseases of the prostate in the elderly using hormones and nutriceuticals

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Daily Consumption for Six Weeks of a Lignan Complex Isolated from Flaxseed Does Not Affect Endothelial Function in Healthy Postmenopausal Women

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Serum Enterolactone Concentration and the Risk of Coronary Heart Disease in a Case-Cohort Study of Finnish Male Smokers

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Intakes of 4 dietary lignans and cause-specific and all-cause mortality in the Zutphen Elderly Study

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A Single Measurement Is Inadequate to Estimate Enterolactone Levels in Danish Postmenopausal Women Due to Large Intraindividual Variation

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Interactions of corn meal or molasses with a soybean-sunflower meal mix or flaxseed meal on production, milk fatty acid composition, and nutrient utilization in dairy cows fed grass hay-based diets

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Urinary Enterolignan Concentrations Are Positively Associated with Serum HDL Cholesterol and Negatively Associated with Serum Triglycerides in U.S.,

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In vitrometabolism of flax lignans by ruminal and faecal microbiota of dairy cows

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Urinary phytoestrogens and cancer, cardiovascular, and all-cause mortality in the continuous National Health and Nutrition Examination Survey

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Phyto-oestrogen intake and plasma concentrations in South Asian and native British women resident in England

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In vitro digestion models for dietary phenolic compounds

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Hypoglycemic effects of the wood of Taxus yunnanensis on streptozotocin-induced diabetic rats and its active components

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Processing of rye bran influences both the fermentation of dietary fibre and the bioconversion of lignans by human faecal flora in vitro

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Quantitative aspects of the metabolism of lignans in pigs fed fibre-enriched rye and wheat bread

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Enterolactone Induces Heme Oxygenase-1 Expression through Nuclear Factor-E2-Related Factor 2 Activation in Endothelial Cells

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Oxidative metabolites and genotoxic potential of mammalian and plant lignans in vitro

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Intakes of 4 dietary lignans and cause-specific and all-cause mortality in the Zutphen Elderly Study 1–3

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HPLC method with fluorescence detection for the quantitative determination of flaxseed lignans

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Biomarkers of Nutritional Exposure and Nutritional Status

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The Adverse Effect of Phytoestrogens on the Synthesis and Secretion of Ovarian Oxytocin in Cattle

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Enterolignans: from natural origins to cardiometabolic significance, including chemistry, dietary sources, bioavailability, and activity

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Gut microbiota in coronary artery disease: a friend or foe?

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A Probiotic Mixture Including Galactooligosaccharides Decreases Fecal β-Glucosidase Activity but Does Not Affect Serum Enterolactone Concentration in Men during a Two-Week Intervention1–3

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Low serum enterolactone concentration is associated with low colonicLactobacillus–Enterococcuscounts in men but is not affected by a synbiotic mixture in a randomised, placebo-controlled, double-blind, cross-over intervention study

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Management of Hypercholesterolemia in Older Persons for the Prevention of Cardiovascular Disease

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A validated method for the quantification of enterodiol and enterolactone in plasma using isotope dilution liquid chromatography with tandem mass spectrometry

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Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice

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Camelina sativa: An Emerging Biofuel Crop

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Occurrence of “mammalian” lignans in plant and water sources

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Plasma enterolignans are not associated with nonfatal myocardial infarction risk

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Can rye intake decrease risk of human breast cancer?

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Highly elevated serum phyto‐oestrogen concentrations in patients with diabetic nephropathy

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New lignan metabolites in rat urine

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Phytoestrogens and Cardiovascular Disease

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Lignan exposure: a worldwide perspective

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Lignans From Taxus Species

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Plasma enterolactone and breast cancer risk in the Nurses’ Health Study II

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Determinants of dietary lignan intake in a representative sample of young Spaniards: association with lower obesity prevalence among boys but not girls

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Dietary Alkylresorcinols and Lignans in the Spanish Diet: Development of the Alignia Database

Moreno‐Franco, B., García‐González, Á., Montero-Bravo, A., Iglesias‐Gutiérrez, E., Úbeda, N., Maroto-Núñez, L., Adlercreutz, H., & Peñalvo, J. L. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2015446 · Cited by 19

The synthesis of multiply 13C‐labelled plant and mammalian lignans as internal standards for LC‐MS and GC‐MS analysis

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Phloem fortification in rye bread elevates serum enterolactone level

Vanharanta, M., Mursu, J., Nurmi, T., Voutilainen, S., Rissanen, T., Salonen, R., Adlercreutz, H., & Salonen, J. (2002) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601510 · Cited by 19

Rye bread and other rye products

Kamal‐Eldin, A., Åman, P., Zhang, J.-X., Knudsen, K. E. B., & Poutanen, K. S. (2008) · Elsevier eBooks · doi:10.1533/9781845693886.2.233 · Cited by 19

Weekly excretion of the mammalian lignan enterolactone in milk of dairy cows fed flaxseed meal

Gagnon, N., Côrtes, C., & Petit, H. V. (2009) · Journal of Dairy Research · doi:10.1017/s0022029909990082 · Cited by 18

Antioxidants and Human Health

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Effect of flaxseed lignans added to milk or fed to cows on oxidative degradation of dairy beverages enriched with polyunsaturated fatty acids

Matumoto‐Pintro, P. T., Petit, H. V., Giroux, H. J., Côrtes, C., Gagnon, N., & Britten, M. (2011) · Journal of Dairy Research · doi:10.1017/s0022029910000853 · Cited by 17

Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmö Diet and Cancer cohort

Sonestedt, E., Ericson, U., Gullberg, B., Peñalvo, J. L., Adlercreutz, H., & Wirfält, E. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602811 · Cited by 17

Flaxseed Ingestion Alters Ratio of Enterolactone Enantiomers in Human Serum

Saarinen, N., Smeds, A. I., Peñalvo, J. L., Nurmi, T., Adlercreutz, H., & Mäkelä, S. (2010) · Journal of Nutrition and Metabolism · doi:10.1155/2010/403076 · Cited by 17

The interaction of monensin and flaxseed hulls on ruminal and milk concentration of the mammalian lignan enterolactone in late-lactating dairy cows

Petit, H. V., Côrtes, C., da Silva, D., Kazama, R., Gagnon, N., Benchaar, C., dos Santos, G. T., & Zeoula, L. M. (2009) · Journal of Dairy Research · doi:10.1017/s0022029909990215 · Cited by 17

Validation of FFQ-based assessment of dietary lignans compared with serum enterolactone in Swedish women

Lin, Y., Wolk, A., Håkansson, N., Peñalvo, J. L., Lagergren, J., Adlercreutz, H., & Lu, Y. (2012) · British Journal Of Nutrition · doi:10.1017/s000711451200387x · Cited by 18

Phytoestrogens and Breast Cancer

Adlercreutz, H., Mazur, W., Heinonen, S., & Stumpf, K. (2002) · CRC Press eBooks · doi:10.1201/b14039-19 · Cited by 17

Lignan Intake and Type 2 Diabetes Incidence Among US Men and Women

Wang, S., Hu, Y., Liu, B., Li, Y., Wang, M., & Sun, Q. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.26367 · Cited by 16

Bioconversion of Pinoresinol into Matairesinol by Use of Recombinant Escherichia coli

Kuo, H.-J., Wei, Z., Lu, P.-C., Huang, P., & Lee, K. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.03397-13 · Cited by 16

Modification of lignans by Trametes hirsuta laccase

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Analysis and Bioavailability of Lignans

Thompson, L. U. (2003) · AOCS Publishing eBooks · doi:10.1201/9781439831915.ch4 · Cited by 16

Rye

Poutanen, K. S., Katina, K., & Heiniö, R. (2014) · doi:10.1002/9781118792001.ch4 · Cited by 16

Pharmacokinetics and Bioavailability of Plant Lignan 7-Hydroxymatairesinol and Effects on Serum Enterolactone and Clinical Symptoms in Postmenopausal Women: A Single-Blinded, Parallel,Dose-Comparison Study

Udani, J. K., Brown, D. J., Tan, M. O. C., & Hardy, M. L. (2013) · Journal of the American College of Nutrition · doi:10.1080/07315724.2013.849578 · Cited by 15

Synthesis of [2H8]‐enterolactone and [2H10]‐enterodiol

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Production performance and milk composition of dairy cows fed different concentrations of flax hulls

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Phytoestrogens and vascular therapy∗∗Editorials published in Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

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Secoisolariciresinol and isotaxiresinol inhibit tumor necrosis factor-α-dependent hepatic apoptosis in mice

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Les lignanes phytoestrogènes du lin sont-ils des bienfaiteurs méconnus?

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New potential mammalian lignan metabolites of environmental phytoestrogens

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Dietary fibre components of rye bran and their fermentation in vitro

Karppinen, S. (2003) · Työväentutkimus Vuosikirja · Cited by 12

Urinary 1 H‐NMR Metabonomics Study on Intervention Effects of Soya Milk in Africans

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C‐Glycosylflavone and Lignan Diglucoside Contents of Commercial, Regular, and Whole‐Wheat Spaghetti

Hirawan, R., & Trust Beta (2011) · Cereal Chemistry · doi:10.1094/cchem-01-10-0010 · Cited by 10

Prenatal developmental toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats

Wolterbeek, A. P. M., Roberts, A. S., Korte, H., Unkila, M., & Waalkens‐Berendsen, D. H. (2004) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2004.04.001 · Cited by 10

Prospective observational study of isoflavone and the risk of stroke recurrence: Potential clinical implications beyond vascular function

Chan, Y.-H., Lau, K. K., Yiu, K., Siu, C.-W., Chan, H.-T., Li, S.-W., Tam, S., Lam, T., Lau, C. P., & Tse, H. (2012) · The journal of nutrition health & aging · doi:10.1007/s12603-012-0048-6 · Cited by 10

Interactions between Plant Bioactive Food Ingredients and Intestinal Flora—Effects on Human Health

Puupponen‐Pimiä, R., Aura, A., Karppinen, S., Oksman‐Caldentey, K., & Poutanen, K. S. (2004) · Bioscience and Microflora · doi:10.12938/bifidus.23.67 · Cited by 10

Effects of abomasal infusion of flaxseed (Linum usitatissimum) oil on microbial β-glucuronidase activity and concentration of the mammalian lignan enterolactone in ruminal fluid, plasma, urine and milk of dairy cows

Côrtes, C., Kazama, D. C. D. S., Kazama, R., Benchaar, C., dos Santos, G. T., Zeoula, L. M., Gagnon, N., & Petit, H. V. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001341 · Cited by 9

Recent Advances Toward Development of Plant Cell Culture Process for Sustainable Production of Lignans and Their Health Benefits

Gabr, A. M. M., Mabrok, H. B., Sytar, O., & Smetanska, I. (2021) · Springer eBooks · doi:10.1007/978-3-030-58271-5_10 · Cited by 9

Exposome-wide ranking of modifiable risk factors for cardiometabolic disease traits

Poveda, A., Pomares‐Millan, H., Chen, Y., Kurbasic, A., Patel, C. J., Renström, F., Hallmans, G., Johansson, I., & Franks, P. W. (2022) · Scientific Reports · doi:10.1038/s41598-022-08050-1 · Cited by 9

Utilidad de los fitoestrógenos en la reducción de la presión arterial. Revisión sistemática y metaanálisis

Arenas, M. Á. R., Arenas, E. R., Armiñana, M. A. P., & García, M. Á. G. (2008) · Atención Primaria · doi:10.1157/13118060 · Cited by 8

Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: A nested case–control study from the Korean Multi‐Center Cancer Cohort

Yang, J. J., Cho, L. Y., Ko, K., Ma, S. H., Shin, A., Choi, B. Y., Han, D. S., Song, K. S., Kim, Y. S., Chang, S.-H., et al. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200169 · Cited by 9

Camelina sativa: An Emerging Biofuel Crop

Chaturvedi, S., Bhattacharya, A., Khare, S. K., & Kaushik, G. (2019) · Springer eBooks · doi:10.1007/978-3-319-73645-7_110 · Cited by 9

Health Benefits of Flaxseed

Fitzpatrick, K. C. (2011) · Omega-3 Oils · doi:10.1016/b978-1-893997-82-0.50013-x · Cited by 8

A thirteen week dietary toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats

Lina, B. A. R., Korte, H., Nyman, L., & Unkila, M. (2004) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2004.09.001 · Cited by 8

Association of enterolactone with blood pressure and hypertension risk in NHANES

Weiner, C. M., Khan, S. E., Leong, C., Ranadive, S. M., Campbell, S. C., Howard, J. T., & Heffernan, K. S. (2024) · PLoS ONE · doi:10.1371/journal.pone.0302254 · Cited by 7

Purification and characterization of SDG-β-d-glucosidase hydrolyzing secoisolariciresinol diglucoside to secoisolariciresinol from Aspergillus oryzae

Zhang, C., Zhong, Y., Sun, X., & Ma, Y. (2009) · Process Biochemistry · doi:10.1016/j.procbio.2009.01.007 · Cited by 7

Technical note: Quantification of lignans in the urine, milk, and plasma of flaxseed cake–fed dairy sheep

Zhuang, C., Feng, X., Xu, H., Zhang, L., Liu, L., Zhang, G., Zheng, Z., & Ma, C. (2020) · Journal of Dairy Science · doi:10.3168/jds.2020-18470 · Cited by 7

β-glucuronidase activity and enterolactone concentration in ruminal fluid, plasma, urine, and milk of Holstein cows fed increased levels of flax (Linum usitatissimum) meal

Schogor, A. L. B., Palin, M., dos Santos, G. T., Benchaar, C., & Petit, H. V. (2016) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2016.11.004 · Cited by 7

Nutraceutical-A deep and profound concept

Kour, J., Chopra, H., Bukhari, S., Sharma, R., Bansal, R., Hans, M., & Saxena, D. C. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89779-2.00021-1 · Cited by 7

The lignan macromolecule from flaxseed : structure and bioconversion of lignans

Struijs, K. (2008) · doi:10.18174/8307 · Cited by 7

Quinupristin/dalfopristin: the first parenteral streptogramin

Stratton, C. W. (2000) · Antimicrobics and Infectious Diseases Newsletter · doi:10.1016/s1069-417x(00)89007-x · Cited by 6

Mining whole grains for functional components

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Weight reduction with improvement of serum lipid profile and ratios of Sesamum radiatum leaves diet in a non-obese Sprague Dawley rats

Shittu, L., Munir, A. B., Olufemi, A. O., Falade, A. K., Remilekun, K. S., Marian, N. B., Ahmed, T., Tayo, A. O., & Ashiru, O. A. (2007) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2007.000-2382 · Cited by 6

Risk of Cardiovascular Disease–Related and All-Cause Death According to Serum Concentrations of Enterolactone

Vanharanta, M., Voutilainen, S., Rissanen, T. H., Adlercreutz, H., & Salonen, J. T. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.9.1099 · Cited by 161

Serum Enterolactone Concentration and the Risk of Coronary Heart Disease in a Case-Cohort Study of Finnish Male Smokers

Kilkkinen, A., Erlund, I., Virtanen, M. J., Alfthan, G., Ariniemi, K., & Virtamo, J. R. K. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj080 · Cited by 37

Original Contribution Serum Enterolactone Concentration and the Risk of Coronary Heart Disease in a Case-Cohort Study of Finnish Male Smokers

Kilkkinen, A., Erlund, I., Virtanen, M. J., Alfthan, G., Ariniemi, K., & Virtamo, J. (2005)

Determinants of serum enterolactone concentration

Kilkkinen, A., Stumpf, K., Pietinen, P., Valsta, L. M., Tapanainen, H., & Adlercreutz, H. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.6.1094 · Cited by 216

Plasma enterolignans are not associated with nonfatal myocardial infarction risk

Kuijsten, A., Bueno-de-Mesquita, H. B., Boer, J. M. A., Arts, I. C. W., Kok, F. J., Veer, P. V., & Hollman, P. C. H. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.06.005 · Cited by 22