Lakka, Timo A.

Genetic studies of body mass index yield new insights for obesity biology

Study, T. L. C., Locke, A. E., The ADIPOGen Consortium, The AGEN-BMI Working Group, The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The, G. L. G. C., The, I. C. B. P., The MAGIC Investigators, The MuTHER Consortium, et al. (2015) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 4,534

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segrè, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, H., Grallert, H., et al. (2012) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,912

Defining the role of common variation in the genomic and biological architecture of adult human height

The Electronic Medical Records and Genomics (eMERGE) Consortium, Wood, A. R., The MIGen Consortium, The PAGE Consortium, Study, T. L. C., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., et al. (2014) · Nature Genetics

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 1,853

New genetic loci link adipose and insulin biology to body fat distribution

The ADIPOGen Consortium, Shungin, D., The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The GEFOS Consortium, The GENIE Consortium, The, G. L. G. C., The, I. C. B. P., The International Endogene Consortium, Study, T. L. C., et al. (2015) · Nature

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,580

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Mahajan, A., Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium, Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., et al. (2014) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,034

Common variants associated with plasma triglycerides and risk for coronary artery disease

Do, R., Willer, C. J., Schmidt, E. M., Sengupta, S., Gao, C., Peloso, G. M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., et al. (2013) · Nature Genetics

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 862

Relation of Leisure-Time Physical Activity and Cardiorespiratory Fitness to the Risk of Acute Myocardial Infarction in Men

Lakka, T. A., Venalainen, J. M., Rauramaa, R., Salonen, R., Tuomilehto, J., & Salonen, J. T. (1994) · New England Journal of Medicine

Physical Activity and HealthCardiovascular and exercise physiology

Cited by 793

Low Levels of Leisure-Time Physical Activity and Cardiorespiratory Fitness Predict Development of the Metabolic Syndrome

Laaksonen, D. E., Lakka, H.-M., Salonen, J. T., Niskanen, L. K., Rauramaa, R., & Lakka, T. A. (2002) · Diabetes Care

Physical Activity and HealthCardiovascular and exercise physiology

Cited by 657

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., et al. (2013) · Nature Genetics

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 646

Physical Activity in the Prevention of Type 2 Diabetes

Laaksonen, D. E., Lindström, J., Lakka, T. A., Eriksson, J. G., Niskanen, L., Wikström, K., Aunola, S., Keinänen-Kiukaanniemi, S., Laakso, M., Valle, T. T., et al. (2005) · Diabetes

Physical Activity and HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 614

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., et al. (2017) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 610

Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine

Valkonen, V.-P., Päivä, H., Salonen, J. T., Lakka, T. A., Lehtimäki, T., Laakso, J., & Laaksonen, R. (2001) · The Lancet

Nitric Oxide and Endothelin EffectsCancer-related gene regulation

Cited by 562

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., et al. (2016) · Science

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 545

Physical activity in prevention and treatment of the metabolic syndrome

Lakka, T. A., & Laaksonen, D. E. (2007) · Applied Physiology, Nutrition, and Metabolism

Physical Activity and HealthCardiovascular and exercise physiology

Cited by 482

Effects of Exercise Training on Glucose Homeostasis

Boulé, N. G., Weisnagel, S. J., Lakka, T. A., Tremblay, A., Bergman, R. N., Rankinen, T., Leon, A. S., Skinner, J. S., Wilmore, J. H., Rao, D. C., et al. (2005) · Diabetes Care

Physical Activity and HealthCardiovascular and exercise physiology

Cited by 356

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., et al. (2016) · Human Molecular Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 343

Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3‐year progression of carotid atherosclerosis

Salonen, J. T., Nyyssönen, K., Salonen, R., Lakka, H. ‐., Kaikkonen, J., Porkkala‐Sarataho, E., Voutilainen, S., Lakka, T. A., Rissanen, T., Leskinen, L., et al. (2000) · Journal of Internal Medicine

Antioxidant Activity and Oxidative StressCardiovascular Health and Disease Prevention

Cited by 327

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Body Iron Stores Are Associated With Serum Insulin and Blood Glucose Concentrations: Population study in 1,013 eastern Finnish men

Tuomainen, T.-P., Nyyssönen, K., Salonen, R., Tervahauta, A., Korpela, H., Lakka, T., Kaplan, G. A., & Salonen, J. T. (1997) · Diabetes Care

Iron Metabolism and DisordersTrace Elements in Health

Cited by 312

Physical activity, cardiovascular risk factors, and mortality among Finnish adults with diabetes

Hu, G., Jousilahti, P., Barengo, N. C., Qiao, Q., Lakka, T. A., & Tuomilehto, J. (2005) · Diabetes Care

Physical Activity and HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 265

Risk of acute coronary events according to serum concentrations of enterolactone: a prospective population-based case-control study

Vanharanta, M., Voutilainen, S., Lakka, T. A., van der Lee, M., Adlercreutz, H., & Salonen, J. T. (1999) · The Lancet

Plant-derived Lignans Synthesis and BioactivityLignin and Wood Chemistry

Cited by 246

Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study

Lakka, T. A., Lakka, H.-M., Rankinen, T., Leon, A. S., Rao, D. C., Skinner, J. S., Wilmore, J. H., & Bouchard, C. (2005) · European Heart Journal

Exercise and Physiological ResponsesAdipokines, Inflammation, and Metabolic Diseases

Cited by 206

Aerobic exercise and the lipid profile in type 1 diabetic men: a randomized controlled trial

LAAKSONEN, D. E., ATALAY, M., NISKANEN, L. K., MUSTONEN, J., &NA;, C. K., LAKKA, T. A., & UUSITUPA, M. I. J. (2000) · Medicine & Science in Sports & Exercise

Cardiovascular and exercise physiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 174