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Cited by 255Biochemical Analysis and Sensing TechniquesRegulation of Appetite and ObesityDiet, Metabolism, and Disease

The DOI matches its Crossref record; 202 of the 202 references it cites were found in a registry or an index.

Carbohydrate taste, appetite, and obesity: An overview

Sclafani, Anthony·1987·Neuroscience & Biobehavioral Reviews
DOI 10.1016/s0149-7634(87)80019-2
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Abstract

This paper reviews previous research on sugar appetite and sugar-induced overeating and obesity in the rat, and previews new findings reported in this issue on the rat's taste and appetite for starch and starch-derived polysaccharides. A variety of behavioral methods demonstrate that rats are very attracted to the taste of sugars. At low molar concentrations their order of preference is maltose greater than sucrose greater than glucose = fructose, while at high concentrations it is sucrose greater than maltose greater than glucose = fructose. New findings indicate that rats are also very attracted to starch-derived polysaccharides, such as Polycose. In fact, Polycose is preferred to sucrose and maltose at low concentrations, and is second only to sucrose in preference at high concentrations. Furthermore, rats taste Polycose as qualitatively different from sucrose. These and other findings suggest that rats as well as other rodents have different taste receptors for sugar and starch. The role of these two taste systems in carbohydrate-induced overeating and obesity is discussed. Rats tend to overeat and become obese when fed sugar or polysaccharide diets, but this response depends critically on the form of the diet. Presenting the carbohydrate as a solution or gel supplement to the diet is much more effective in promoting hyperphagia and obesity than is presenting it as a powder supplement or as part of a composite diet. The differential response to hydrated and dehydrated foods may occur because carbohydrates are absorbed at a faster rate in hydrated forms than in dehydrated forms. The postingestive actions of carbohydrates also modulate the rat's preference for carbohydrate tastes and flavors. Other factors that influence carbohydrate appetite and intake include the availability of the carbohydrate source and the macronutrient composition of the diet. Thus, several factors in addition to taste determine the response of rats to carbohydrate foods.

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Crossref · 10.1016/s0149-7634(87)80019-2

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Citations

Cites

Show all 202 references

Research works printed but not linked: 14

  1. Cantor, 1977, Sweetness—A supernormal reinforcer, Chemtech, 7, 214
  2. Castonguay, 1986, Diet balancing: some limitations, Nutr Behav, 3, 43
  3. Castonguay, 1985, Sucrose procurement cost and dietary selection, Nutr Behav, 2, 201
  4. Geiselman, 1986, The roles of visceral and direct oral stimulation in short-term feeding: what distinctions can be made between appetite and hunger?, Nutr Behav, 3, 75
  5. Greenwood, 1986, Polyunsaturated fat diets increase carbohydrate preference in rats, Soc Neurosci Abstr, 12, 795
  6. Joyner, 1985, Stimulation of sham feeding in the rat by sucrose, maltose, glucose and fructose, Soc Neurosci Abstr, 11, 1223
  7. Michaelis, 1981, Effect of dietary carbohydrate on systolic blood pressure of normotensive and hypertensive rats, Nutr Rep Int, 23, 261
  8. Nissenbaum, 1984, Atropine inhibition of sham feeding: temporal factors, Soc Neurosci Abstr, 10, 1008
  9. Sclafani, 1985, Influence of taste and nutrition on the sugar appetite of rats, Nutr Behav, 3, 57
  10. Soulairac, 1944, Action de l'insuline sur la consummation de differents glucides chez la souris, C R Soc Biol (Paris), 138, 119
  11. Trout, 1978, Dietary regimens for inducing mild hyperphagia, obesity and hyperinsulinemia in rats, Nutr Rep Int, 18, 227
  12. Vasselli, 1982, Effects of acarbose (Bay g 5421) on body weight, insulin, and oral glucose and sucrose tolerance in sucrose-consuming rats, Nutr Behav, 1, 21
  13. Vigorito, 1986, Effects of vagotomy on sucrose intake in rats, Soc Neurosci Abstr, 12, 1295
  14. Walker, 1983, Does sugar cause or promote obesity?, S Afr J Sci, 79, 43

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Metadata

Authors
Sclafani, A.
Affiliations
City University of New York (US)
Corresponding author
Sclafani, Anthony
ORCID
Sclafani, Anthony
Venue
Neuroscience & Biobehavioral Reviews
Publisher
Elsevier BV
Published
1987-06
Volume
11
Issue
2
Pages
131-153
ISSN
0149-7634 (ISSN-L)
DOI
10.1016/s0149-7634(87)80019-2
OpenAlex
W1995303077
Cited by
255
References
202
Citations by year
2026: 2 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 5 · 2020: 3 · 2019: 6 · 2018: 9 · 2017: 11 · 2016: 6 · 2015: 7 · 2014: 8 · 2013: 6 · 2012: 6
FWCI
17.95
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Neuroscience & Biobehavioral Reviews (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Diabetes and Digestive and Kidney Diseases (DK-31135)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
Keywords
obesity, Polycose, sucrose, maltose, glucose, fructose, taste receptors, hyperphagia, macronutrient composition, food availability
MeSH terms
Animals, Appetite, Carbohydrate Conformation, Dietary Carbohydrates, Feeding Behavior, Female, Glucose, Humans, Hyperphagia, Male, Obesity, Sex Factors, Sucrose, Taste, Taste Threshold, Rats

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