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The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity
Abstract
Background A self-rating inventory has been developed to measure DSM-IV and ICD-10 diagnoses of major (moderate to severe) depression by the patients' self-reported symptoms. This Major Depression Inventory (MDI) can be scored both according to the DSM-IV and the ICD-10 algorithms for depressive symptomatology and according to severity scales by the simple total sum of the items.Methods The Schedule for Clinical Assessment in Neuropsychiatry (SCAN) was used as index of validity for the clinician's DSM-IV and ICD-10 diagnosis of major (moderate to severe) depression. The sensitivity and specificity of MDI was assessed in a sample of 43 subjects covering a spectrum of depressive symptoms.Results The sensitivity of the MDI algorithms for major depression varied between 0.86 and 0.92. The specificity varied between 0.82 and 0.86. When using the total score of MDI the optimal cut-off score was estimated 26 and the total score was shown to be a sufficient statistic.Limitations The sample of subjects was limited. Patients with psychotic depression were not included.Conclusion The MDI was found to have a sensitivity and specificity which is acceptable. The questionnaire is brief and can be scored diagnostically by the DSM-IV and ICD-10 algorithms as well as by its simple total score.
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“Depression, for example, was measured using four different scales: eight-item Patient Health Questionnaire depression scale (PHQ-8) (Kroenke 2009); Major Depression Inventory (MDI) (Bech 2001); Center for Epidemiologic Studies Depression Scale (CES-D) (Radloff 1977); and Hospital Anxiety and Depression Scale (HADS) (Zigmond 1983); anxiety using three: HADS (Zigmond 1983), State-Trait Anxiety Inven”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Bech 2001
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Metadata
- Authors
- Bech, P., Rasmussen, N.-A., Olsen, L. R., Noerholm, V., & Abildgaard, W.
- Affiliations
- Aarhus University Hospital (DK)
- Corresponding author
- Bech, P.
- ORCID
- Bech, P.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2001-10
- Volume
- 66
- Issue
- 2-3
- Pages
- 159-164
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W1998903052
- Cited by
- 975
- References
- 22
- Citations by year
- 2026: 32 · 2025: 44 · 2024: 46 · 2023: 58 · 2022: 59 · 2021: 87 · 2020: 65 · 2019: 60 · 2018: 61 · 2017: 59 · 2016: 59 · 2015: 56 · 2014: 62 · 2013: 46 · 2012: 38
- FWCI
- 12.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Keywords
- Major Depression Inventory, major depressive disorder, self-report questionnaire, diagnostic validity, sensitivity and specificity, DSM-IV diagnostic criteria, ICD-10 diagnostic criteria, cut-off values, depression severity
- MeSH terms
- Adult, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Personality Inventory, Psychiatric Status Rating Scales, Psychometrics, Reproducibility of Results
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