Cited by 553Memory and Neural MechanismsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 41 of the 43 references it cites were found in a registry or an index.

Anxiolytic action on the behavioural inhibition system implies multiple types of arousal contribute to anxiety

McNaughton, Neil, Gray, Jeffrey A.·2000·Journal of Affective Disorders

DOI 10.1016/s0165-0327(00)00344-x

Open this paper in CoChat — free account

Abstract

According to "The Neuropsychology of Anxiety" [Gray, J.A., 1982, The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-hippocampal System, Oxford University Press, Oxford; Gray, J.A., McNaughton, N., 2000, The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-hippocampal System, 2nd ed., Oxford University Press, Oxford], anxiolytic drugs of all types act on a behavioural inhibition system, the most important neural component of which is the septo-hippocampal system. Anxiolytics affect septo-hippocampal function by impairing the subcortical control of hippocampal "theta" activity - the principle response of the septo-hippocampal system to arousal. Our recent experiments show that there are multiple systems controlling theta activity and that anxiolytics act on several, but not all, of these systems. This pattern of results implies that there are many different types of arousal, only some of which appear to contribute to the generation of anxiety in normal subjects and to the etiology of pathological anxiety.

Integrity signals

Registry

Crossref · 10.1016/s0165-0327(00)00344-x

Cites

41 of 41 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Untitled work
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010
The hippocampus as a cognitive map
Passingham, R. E. (1979) · Neuroscience · doi:10.1016/0306-4522(79)90015-0 · Cited by 5,128
Précis of The neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system
Gray, J. A. (1982) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00013066 · Cited by 4,477
Self-citation
Handbook of Psychopharmacology
Iversen, L. L., Iversen, S. D., & Snyder, S. H. (1988) · Springer eBooks · doi:10.1007/978-1-4613-0933-8 · Cited by 2,756
The Neuropsychology of Anxiety
Gray, J. A., & McNaughton, N. (2003) · doi:10.1093/acprof:oso/9780198522713.001.0001 · Cited by 1,953
Self-citation
Hippocampal electrical activity and voluntary movement in the rat
Vanderwolf, C. H. (1969) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(69)90092-3 · Cited by 1,928
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536
HIPPOCAMPAL ELECTRICAL ACTIVITY IN AROUSAL
Green, J. D., & Arduini, A. (1954) · Journal of Neurophysiology · doi:10.1152/jn.1954.17.6.533 · Cited by 1,396
Fear conditioning induces associative long-term potentiation in the amygdala
Rogan, M. T., Stäubli, U. V., & LeDoux, J. E. (1997) · Nature · doi:10.1038/37601 · Cited by 1,310
The amygdala: Neurobiological aspects of emotion, memory and mental dysfunction
Scheel-Krüger, J. (1993) · Journal of Chemical Neuroanatomy · doi:10.1016/0891-0618(93)90037-5 · Cited by 1,281

Show all 43 references

Research works printed but not linked: 2

McNaughton, 1997, Cholinergic relays in superior colliculus, substantia nigra and amygdala co-operate to gate theta activity, Soc. Neurosci. Abstr., 23, 487
Vertes, 1997, Brainstem-diencephalo-septohippocampal systems controlling the theta rhythm of the hippocampus, Neuroscience, 81, 893

Sorted by citations

Items 101–200 of 553

Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers
Adams, P. E., Adams, J. S., Nguyen, D. V., Hessl, D. R., Brunberg, J. A., Tassone, F., Zhang, W., Koldewyn, K., Rivera, S. M., Grigsby, J., et al. (2009) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31046 · Cited by 65
Functional Amygdala-Hippocampus Connectivity During Anticipation of Aversive Events is Associated with Gray's Trait “Sensitivity to Punishment”
Hahn, T., Dresler, T., Plichta, M. M., Ehlis, A.-C., Ernst, L. H., Markulin, F., Polak, T., Blaimer, M., Deckert, J., Lesch, K.-P., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.04.033 · Cited by 63
Relaxin’ the brain: a case for targeting the nucleus incertus network and relaxin‐3/RXFP3 system in neuropsychiatric disorders
Kumar, J. R., Rajkumar, R., Jayakody, T., Marwari, S., Hóng, J., Ma, S., Gundlach, A. L., Lai, M. K. P., & Dawe, G. S. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13564 · Cited by 63
Electrophysiological evidence for greater attention to threat when cognitive control resources are depleted
Holmes, A., Mogg, K., de Fockert, J. W., Nielsen, M. K., & Bradley, B. P. (2013) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-013-0212-4 · Cited by 63
Anxiolytic profile of pregabalin on elicited hippocampal theta oscillation
Siok, C. J., Taylor, C. P., & Hajós, M. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.09.013 · Cited by 62
Antiaversive Effects of Cannabinoids: Is the Periaqueductal Gray Involved?
Moreira, F. A., de Aguiar, D. C., Campos, A. C., Lisboa, S. F. D. S., Terzian, A. L. B., Resstel, L. B. M., & Guimarães, F. S. (2008) · Neural Plasticity · doi:10.1155/2009/625469 · Cited by 62
The relationship between personality, coping strategies and alcohol use
Naim‐Feil, J., & Hasking, P. A. (2008) · Addiction Research & Theory · doi:10.1080/16066350802025714 · Cited by 66
Altered brain activity and the effect of personality traits in excessive smartphone use during facial emotion processing
Chun, J.-W., Choi, J., Kim, J.-Y., Cho, H., Ahn, K.-J., Nam, J.-H., Choi, J.-S., & Kim, D.-J. (2017) · Scientific Reports · doi:10.1038/s41598-017-08824-y · Cited by 60
Low Heart Rate: A Marker of Stress Resilience. The TRAILS Study
Oldehinkel, A. J., Verhulst, F. C., & Ormel, J. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.12.006 · Cited by 60
Approach and Avoidance as Organizing Structures for Motivated Distance Perception
Balcetis, E. (2015) · Emotion Review · doi:10.1177/1754073915586225 · Cited by 66
Developmental underpinnings of differences in rodent novelty‐seeking and emotional reactivity
Clinton, S. M., Stead, J. D. H., Miller, S., Watson, S. J., & Akil, H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07811.x · Cited by 58
“…the hippocampus detects novelty (Roullet & Lassalle, 1990; Lever et al., 2006; Jeewajee et al., 2008), regulates neural stress circuits (Sapolsky et al., 1984; Jacobson & Sapolsky, 1991) and controls fear and anxiety-like behavior (Gray, 1982; McNaughton & Gray, 2000; Bannerman et al., 2002).”
BackgroundResult
Endogenous IL-1 in Cognitive Function and Anxiety: A Study in IL-1RI−/− Mice
Murray, C., Obiang, P., Bannerman, D. M., & Cunningham, C. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078385 · Cited by 57
Altered emotionality, hippocampus-dependent performance and expression of NMDA receptor subunit mRNAs in chronically stressed mice
Costa-Nunes, J. P., Zubareva, O. E., Araújo-Correia, M., Valença, A., Schroeter, C. A., Pawluski, J. L., Vignisse, J., Steinbusch, H. P., Hermes, D. J. H. P., Phillipines, M., et al. (2013) · Stress · doi:10.3109/10253890.2013.872619 · Cited by 56
Fearfulness in a large N/Nih genetically heterogeneous rat stock: Differential profiles of timidity and defensive flight in males and females
López-Aumatell, R., Guitart‐Masip, M., Vicens-Costa, E., Giménez‐Llort, L., Valdar, W. S. J., Johannesson, M., Jonathan Flint, C., Tobeña, A., & Fernández‐Teruel, A. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.10.015 · Cited by 53
Environmental enrichment eliminates the anxiety phenotypes in a triple transgenic mouse model of Alzheimer’s disease
Pietropaolo, S., Feldon, J., & Yee, B. K. (2014) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-014-0253-3 · Cited by 54
Cerebral Cortical Activity Following Non-invasive Cerebellar Stimulation—a Systematic Review of Combined TMS and EEG Studies
Fernández, L., Rogasch, N. C., Do, M., Clark, G. M., Major, B. P., Teo, W., Byrne, L. K., & Enticott, P. G. (2020) · The Cerebellum · doi:10.1007/s12311-019-01093-7 · Cited by 56
Integrative Review and Framework of Suggested Mechanisms in Primary Muscle Tension Dysphonia
Desjardins, M., Apfelbach, C. S., Rubino, M., & Abbott, K. V. (2022) · Journal of Speech Language and Hearing Research · doi:10.1044/2022_jslhr-21-00575 · Cited by 54
Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: Implications for role of relaxin-3/RXFP3 signalling in sustained arousal
Hosken, I. T., Sutton, S. W., Smith, C. M., & Gundlach, A. L. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.09.028 · Cited by 55
Filling the gaps: Cognitive control as a critical lens for understanding mechanisms of value-based decision-making
Frömer, R., & Shenhav, A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.12.006 · Cited by 57
Striatopallidal neurons control avoidance behavior in exploratory tasks
LeBlanc, K. H., London, T. D., Szczot, I., Bocarsly, M. E., Friend, D. M., Nguyen, K. P., Mengesha, M. M., Rubinstein, M., Alvarez, V. A., & Kravitz, A. V. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0051-3 · Cited by 46
Stress and anxious-related behaviors in Lurcher mutant mice
Hilber, P., Lorivel, T., Delarue, C., & Caston, J. (2004) · Brain Research · doi:10.1016/j.brainres.2004.01.008 · Cited by 51
Behavioral inhibition: A neurobiological perspective
Morgan, B. E. (2006) · Current Psychiatry Reports · doi:10.1007/s11920-006-0062-7 · Cited by 50
Region‐specific response of the hippocampus to chronic unpredictable stress
Hawley, D. F., & Leasure, J. L. (2011) · Hippocampus · doi:10.1002/hipo.20970 · Cited by 54
Emotion and Political Psychology
Gadarian, S. K., & Brader, T. A. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197541302.013.5 · Cited by 54
Effects of an attachment-based intervention in infancy on children’s autonomic regulation during middle childhood
Tabachnick, A. R., Raby, K. L., Goldstein, A., Zajac, L. A., & Dozier, M. (2019) · Biological Psychology · doi:10.1016/j.biopsycho.2019.01.006 · Cited by 60
Dissociable influences of reward and punishment on adaptive cognitive control
Leng, X., Yee, D. M., Ritz, H., & Shenhav, A. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009737 · Cited by 59
Models of anger: contributions from psychophysiology, neuropsychology and the cognitive behavioral perspective
Cox, D. E., & Harrison, D. W. (2008) · Brain Structure and Function · doi:10.1007/s00429-007-0168-7 · Cited by 51
Modulation of anxiety by μ-opioid receptors of the lateral septal region in mice
Merrer, J. L., Cagniard, B., & Cazala, P. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.03.008 · Cited by 46
Anxious anticipation and pain: the influence of instructed vs conditioned threat on pain
Reicherts, P., Wiemer, J., Gerdes, A. B. M., Schulz, S. M., Pauli, P., & Wieser, M. J. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw181 · Cited by 48
Rethinking Research on Prediction and Prevention of Psychotherapy Dropout: A Mechanism-Oriented Approach
Cooper, A. A., Kline, A. C., Baier, A. L., & Feeny, N. C. (2018) · Behavior Modification · doi:10.1177/0145445518792251 · Cited by 52
Probing the limits of delay intolerance: Preliminary young adult data from the Delay Frustration Task (DeFT)
Bitsakou, P., Antrop, I., Wiersema, J. R., & Sonuga-Barke, E. J. S. (2006) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2005.06.031 · Cited by 45
Ascending Control of Arousal and Motivation: Role of Nucleus Incertus and its Peptide Neuromodulators in Behavioural Responses to Stress
Ma, S., & Gundlach, A. L. (2015) · Journal of Neuroendocrinology · doi:10.1111/jne.12259 · Cited by 44
Psychoacoustic Tinnitus Loudness and Tinnitus-Related Distress Show Different Associations with Oscillatory Brain Activity
Balkenhol, T., Wallhäußer-Franke, E., & Delb, W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053180 · Cited by 45
Brain responses to uncertainty about upcoming rectal discomfort in quiescent Crohn's disease – a fMRI study
Rubio, A., Sonia Pellissier, A., Oudenhove, L. V., Ly, H. G., Dupont, P. J., Tack, J. F., Dantzer, C., Delon‐Martin, C., & Bonaz, B. L. (2016) · Neurogastroenterology & Motility · doi:10.1111/nmo.12844 · Cited by 47
Tolerance to Sedative/Hypnotic Actions of GABAergic Drugs Correlates With Tolerance to Potentiation of Extrasynaptic Tonic Currents of Alcohol-Dependent Rats
Liang, J., Spigelman, I., & Olsen, R. W. (2009) · Journal of Neurophysiology · doi:10.1152/jn.90484.2008 · Cited by 44
Selective tuning of hippocampal oscillations by phasic locus coeruleus activation in awake male rats
Walling, S. G., Brown, R. A. M., Milway, J. S., Earle, A. G., & Harley, C. W. (2010) · Hippocampus · doi:10.1002/hipo.20816 · Cited by 42
Two-way avoidance acquisition is negatively related to conditioned freezing and positively associated with startle reactions: A dissection of anxiety and fear in genetically heterogeneous rats
Vicens-Costa, E., Martínez-Membrives, E., López-Aumatell, R., Guitart‐Masip, M., Cañete, T., Blázquez, G., Tobeña, A., & Fernández‐Teruel, A. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.12.009 · Cited by 42
A latent variable analysis of the Psychopathy Checklist–Revised and behavioral inhibition system/behavioral activation system factors in North American and Swedish offenders.
Hoppenbrouwers, S. S., Neumann, C. S., Lewis, J., & Johansson, P. (2015) · Personality Disorders Theory Research and Treatment · doi:10.1037/per0000115 · Cited by 42
5-HT2C receptor regulation of defensive responses in the rat dorsal periaqueductal gray
Yamashita, P., de Bortoli, V. C., & Zangrossi, H. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.09.001 · Cited by 42
Between Action and Emotional Survival During the COVID-19 era: Sensorimotor Pathways as Control Systems of Transdiagnostic Anxiety-Related Intolerance to Uncertainty
Goldstein Ferber, S., Shoval, G., Zalsman, G., Mikulincer, M., & Weller, A. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.680403 · Cited by 40
Behavioral anxiolysis without reduction of hippocampal theta frequency after histamine application in the lateral septum of rats
Chee, S. A., Menard, J. L., & Dringenberg, H. C. (2014) · Hippocampus · doi:10.1002/hipo.22244 · Cited by 41
Chronic activation of the relaxin‐3 receptor on GABA neurons in rat ventral hippocampus promotes anxiety and social avoidance
Rytova, V., Ganella, D. E., Hawkes, D. J., Bathgate, R. A. D., Ma, S., & Gundlach, A. L. (2019) · Hippocampus · doi:10.1002/hipo.23089 · Cited by 40
Transient Plasticity of Hippocampal CA1 Neuron Glutamate Receptors Contributes to Benzodiazepine Withdrawal-Anxiety
Sickle, B. J. V., Xiang, K., & Tietz, E. I. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300531 · Cited by 42
Age increases anxiety and reactivity of the fear/anxiety circuit in Lewis rats
Meyza, K. Z., Boguszewski, P. M., Nikolaev, E., & Zagrodzka, J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.07.011 · Cited by 40
Influence of the BDNF Genotype on Amygdalo-Prefrontal White Matter Microstructure is Linked to Nonconscious Attention Bias to Threat
Carlson, J. M., Cha, J., Harmon‐Jones, E., Mujica-Parodi, L. R., & Hajcak, G. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht089 · Cited by 43
LMX Differentiation and Voice Behavior: A Resource-Conservation Framework
Dong, Y., Jiang, J., Rong, Y., & Yang, B. (2020) · Journal of Leadership & Organizational Studies · doi:10.1177/1548051820911354 · Cited by 44
The Threatened Brain
Maren, S. (2007) · Science · doi:10.1126/science.1147797 · Cited by 41
Instrumental aversion coding in the basolateral amygdala and its reversion by a benzodiazepine
Jean-Richard-dit-Bressel, P., Tran, J., Didachos, A., & McNally, G. P. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01176-2 · Cited by 41
Opinion on monoaminergic contributions to traits and temperament
Robbins, T. W. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0153 · Cited by 37
Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1-Containing α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptors in Hippocampal CA1 Neurons
Song, J., Shen, G., Greenfield, L. J., & Tietz, E. I. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.121798 · Cited by 38
Stepping up the pressure: arousal can be associated with a reduction in male aggression
Ward, A. C., Mann, T. L., Westling, E. H., Creswell, J. D., Ebert, J. P., & Wallaert, M. (2008) · Aggressive Behavior · doi:10.1002/ab.20270 · Cited by 39
Role of 5-HT1A receptors in the ventral hippocampus in the regulation of anxiety- and panic-related defensive behaviors in rats
Hernandes, P. M., Batistela, M. F., Vilela‐Costa, H. H., Sant’Ana, A. B., Kümpel, V. D., Tirapelle, M. C., Bom, A. D. O. P., de Andrade, T. G. C. S., & Zangrossi, H. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113296 · Cited by 38
Functional inactivation of the rat hippocampus disrupts avoidance of a moving object
Telenský, P., Svoboda, J., Blahna, K., Bureš, J., Kubík, Š., & Stuchlı́k, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102525108 · Cited by 37
Different Views of Anxiety Disorders
Selek, S. (2011) · InTech eBooks · doi:10.5772/1022 · Cited by 39
Tonic Immobility and PTSD in a Large Community Sample
Hagenaars, M. A. (2016) · Journal of Experimental Psychopathology · doi:10.5127/jep.051915 · Cited by 37
Bright light suppresses hyperactivity induced by excitotoxic dorsal hippocampus lesions in the rat.
Godsil, B. P., Stefanacci, L., & Fanselow, M. S. (2005) · Behavioral Neuroscience · doi:10.1037/0735-7044.119.5.1339 · Cited by 37
Role of ventral hippocampal nitric oxide/cGMP pathway in anxiety-related behaviors in rats submitted to the elevated T-maze
Calixto, A. V., Duarte, F. S., Duzzioni, M., Häckl, L. P. N., Faria, M. S., & de Lima, T. C. M. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.09.037 · Cited by 37
Anxiolytic-like effect of noradrenaline microinjection into the dorsal periaqueductal gray of rats
Pelosi, G. G., Resstel, L. B. M., Soares-Rachetti, V. D. P., Zangrossi, H., Guimarães, F. S., & Corrêa, F. M. D. A. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32832c7098 · Cited by 36
Genetic influences in emotional dysfunction and alcoholism-related brain damage
Oscar‐Berman, M., & Bowirrat, A. (2005) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.a788 · Cited by 37
Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice
Klaus, F., Paterna, J., Marzorati, E., Sigrist, H., Goetze, L., Schwendener, S., Bergamini, G., Jehli, E., Azzinnari, D., Fuertig, R., et al. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.08.001 · Cited by 37
Reward Responsiveness in the Adolescent Brain Cognitive Development (ABCD) Study: African Americans’ Diminished Returns of Parental Education
Assari, S., Boyce, S., Akhlaghipour, G., Bazargan, M., & Caldwell, C. H. (2020) · Brain Sciences · doi:10.3390/brainsci10060391 · Cited by 36
Neonatal fibroblast growth factor treatment enhances cocaine sensitization
Clinton, S. M., Turner, C. A., Flagel, S. B., Simpson, D. N., Watson, S. J., & Akil, H. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2012.07.006 · Cited by 35
Differential actions of diazepam and zolpidem in basolateral and central amygdala nuclei
Kang-Park, M.-H., Wilson, W. A., & Moore, S. D. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00340-x · Cited by 35
Increased AMPA receptor GluR1 subunit incorporation in rat hippocampal CA1 synapses during benzodiazepine withdrawal
Das, P., Lilly, S. M., Zerda, R., Gunning, W. T., Álvarez, F. J., & Tietz, E. I. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21866 · Cited by 36
The Unintended Consequences of Empowering Leadership: Increased Deviance for Some Followers
Yam, K. C., Reynolds, S. J., Zhang, P., & Su, R. (2021) · Journal of Business Ethics · doi:10.1007/s10551-021-04917-x · Cited by 35
Identifying Uncertainty States during Wayfinding in Indoor Environments: An EEG Classification Study
Zhu, B., Cruz-Garza, J. G., Yang, Q., Shoaran, M., & Kalantari, S. (2021) · Advanced Engineering Informatics · doi:10.1016/j.aei.2022.101718 · Cited by 34
The brain acid–base homeostasis and serotonin: A perspective on the use of carbon dioxide as human and rodent experimental model of panic
Leibold, N. K., van den Hove, D., Esquivel, G., Cort, K. D., Goossens, L., Strackx, E., Buchanan, G. F., Steinbusch, H. W. M., Lesch, K., & Schruers, K. R. J. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.04.001 · Cited by 34
Impaired visual discrimination learning in anorexia nervosa
Lawrence, A. D., Dowson, J. H., Foxall, G., Summerfield, R., Robbins, T. W., & Sahakian, B. J. (2003) · Appetite · doi:10.1016/s0195-6663(02)00138-1 · Cited by 34
Differences Between Two Psychogenetically Selected Lines of Rats in a Swimming Pool Matching-To-Place Task: Long-Term Effects of Infantile Stimulation
Aguilar, R., Escorihuela, R. M., Gil, L., Tobeña, A., & Fernández‐Teruel, A. (2002) · Behavior Genetics · doi:10.1023/a:1015253807488 · Cited by 34
The unbalanced behavioral activation and inhibition system sensitivity in internet gaming disorder: Evidence from resting-state Granger causal connectivity analysis
Dong, H., Zheng, H., Wang, M., Ye, S., & Dong, G. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110582 · Cited by 31
Risky riders: A comparison of personality theories on motorcyclist riding behaviour
Antoniazzi, D., & Klein, R. G. (2018) · Transportation Research Part F Traffic Psychology and Behaviour · doi:10.1016/j.trf.2018.12.008 · Cited by 33
Resting anxiety increases EEG delta–beta correlation: Relationships with the Reinforcement Sensitivity Theory Personality traits
Pascalis, V. D., Vecchio, A., & Cirillo, G. (2019) · Personality and Individual Differences · doi:10.1016/j.paid.2019.109796 · Cited by 31
Genetic Vulnerability to Affective Psychopathology in Childhood: A Combined Voxel-Based Morphometry and Functional Magnetic Resonance Imaging Study
Mechelli, A., Tognin, S., McGuire, P. K., Prata, D. P., Sartori, G., Fusar‐Poli, P., Brito, S. A. D., Hariri, A. R., & Viding, E. M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.01.033 · Cited by 30
Effects of septal cholinergic lesion on rat exploratory behavior in an open-field
Lamprea, M. R., Cárdenas, F. P., Silveira, R., Walsh, T. J., & Morato, S. (2003) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2003000200011 · Cited by 31
How Fear Differs from Anxiety
Catherall, D. R. (2003) · Traumatology An International Journal · doi:10.1177/153476560300900202 · Cited by 32
Prefrontal and hippocampal theta rhythm show anxiolytic‐like changes during periaqueductal‐elicited “panic” in rats
Silva, C., Young, C. K., & McNaughton, N. (2022) · Hippocampus · doi:10.1002/hipo.23459 · Cited by 29
Self-citation
The estrous cycle modulates early-life adversity effects on mouse avoidance behavior through progesterone signaling
Laham, B. J., Murthy, S. S., Hanani, M., Clappier, M., Boyer, S., Vasquez, B., & Gould, E. (2022) · Nature Communications · doi:10.1038/s41467-022-35068-w · Cited by 32
Individual traits are associated with pro‐environmental behaviour: Environmental sensitivity, nature connectedness and consideration for future consequences
Dunne, H., Lionetti, F., Pluess, M., & Setti, A. (2024) · People and Nature · doi:10.1002/pan3.10581 · Cited by 32
Involvement of the CA1 GABAA receptors in MK-801-induced anxiolytic-like effects
Naseri, M. H., Tackallou, S. H., Nami, M., Zarrindast, M., & Nasehi, M. (2014) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000037 · Cited by 28
Affective traits and history of depression are related to ventral striatum connectivity
DelDonno, S. R., Jenkins, L. M., Crane, N. A., Nusslock, R., Ryan, K. A., Shankman, S. A., Phan, K. L., & Langenecker, S. A. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.06.014 · Cited by 29
The Role of miR-150 in Stress-Induced Anxiety-Like Behavior in Mice
Zhang, W., Cao, W.-Y., Huang, Y., Cui, Y., Tu, B.-X., Wang, L.-F., Zou, G.-J., Liu, Y., Hu, Z., Hu, R., et al. (2018) · Neurotoxicity Research · doi:10.1007/s12640-018-9943-x · Cited by 27
GABAergic neurons of the medial septum play a nodal role in facilitation of nociception-induced affect
Ang, S. T., Lee, A. T.-H., Foo, F. C., Ng, L., Low, C., & Khanna, S. (2015) · Scientific Reports · doi:10.1038/srep15419 · Cited by 27
Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors
Kumar, J. R., Rajkumar, R., Lee, L. C., & Dawe, G. S. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.07.019 · Cited by 27
Examination of developmental pathways from preschool temperament to early adolescent ADHD symptoms through initial responsiveness to reward
Bunford, N., Kujawa, A., Dyson, M. W., Olino, T. M., & Klein, D. N. (2021) · Development and Psychopathology · doi:10.1017/s0954579420002199 · Cited by 27
Stimulation of 5-HT1A or 5-HT2A receptors in the ventrolateral periaqueductal gray causes anxiolytic-, but not panicolytic-like effect in rats
DEPAULASOARES, V., & ZANGROSSIJR, H. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.08.027 · Cited by 27
MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning.
Cunningham, J. I., Raudensky, J., Tonkiss, J., & Yamamoto, B. K. (2009) · Behavioral Neuroscience · doi:10.1037/a0016716 · Cited by 27
Hippocampal interplay with the nucleus accumbens is critical for decisions about time
Abela, A. R., Duan, Y., & Chudasama, Y. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.13009 · Cited by 25
Influence of childhood adversity, approach motivation traits, and depression on individual differences in brain activation during reward anticipation
DelDonno, S. R., Mickey, B. J., Pruitt, P. J., Stange, J. P., Hsu, D. T., Weldon, A. L., Zubieta, J.-K., & Langenecker, S. A. (2019) · Biological Psychology · doi:10.1016/j.biopsycho.2019.05.009 · Cited by 26
Neuroanatomia do transtorno de pânico
Mezzasalma, M. A., Valença, A. M., Lopes, F. L., Nascimento, I., Zin, W. A., & Nardi, A. E. (2004) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462004000300010 · Cited by 27
A novel differential susceptibility gene: CHRNA4 and moderation of the effect of maltreatment on child personality
Grazioplene, R. G., DeYoung, C. G., Rogosch, F. A., & Cicchetti, D. (2012) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12031 · Cited by 26
The neural correlates of reinforcement sensitivity theory: A systematic review of the (f)MRI literature.
Standen, B., Firth, J., Sumich, A. L., & Heym, N. (2022) · Psychology & Neuroscience · doi:10.1037/pne0000284 · Cited by 29
Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders
Hunsaker, M. R. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.12.001 · Cited by 26
Early dysfunction of central 5-HT system in a murine model of bovine spongiform encephalopathy
Vidal, C., Herzog, C., Haeberle, A.-M., Bombarde, C., Miquel, M., Carimalo, J., Launay, J., Mouillet‐Richard, S., Lasmézas, C. I., Dormont, D., et al. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.02.072 · Cited by 29
Neuropsychological Theory as a Basis for Clinical Translation of Animal Models of Neuropsychiatric Disorder
McNaughton, N. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.877633 · Cited by 24
Self-citation
A brainstem circuit amplifies aversion
Liang, J., Zhou, Y., Feng, Q., Zhou, Y., Jia, X., Ren, M., Jia, X., Gong, H., Di, R., Jiao, P., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.08.010 · Cited by 28
The frequency of hippocampal theta rhythm is modulated on a circadian period and is entrained by food availability
Munn, R. G. K., Tyree, S. M., McNaughton, N., & Bilkey, D. K. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00061 · Cited by 24
Self-citation
Anxiety and Hyperlocomotion Induced by Chronic Unpredictable Mild Stress Can Be Moderated with Melatonin Treatment
Spasojević, N., Stefanović, B., Jovanović, P., & Dronjak, S. (2016) · Folia Biologica · doi:10.14712/fb2016062060250 · Cited by 24
Humans perseverate on punishment avoidance goals in multigoal reinforcement learning
Sharp, P. B., Russek, E. M., Huys, Q. J. M., Dolan, R. J., & Eldar, E. (2022) · eLife · doi:10.7554/elife.74402 · Cited by 25
Toward Linguistic Recognition of Generalized Anxiety Disorder
Rook, L., Mazza, M. C., Lefter, I., & Brazier, F. M. T. (2022) · Frontiers in Digital Health · doi:10.3389/fdgth.2022.779039 · Cited by 27
Effects of early protein malnutrition and environmental stimulation on behavioral and biochemical parameters in rats submitted to the elevated plus-maze test
Soares, R. O., Oliveira, L. M., Marchini, J. S., Antunes‐Rodrigues, J., Elias, L. L. K., & Almeida, S. S. (2013) · Nutritional Neuroscience · doi:10.1179/1476830512y.0000000036 · Cited by 24

Authors: McNaughton, N., & Gray, J. A.
Affiliations: University of Otago (NZ)
Maudsley Hospital (GB)
Corresponding author: McNaughton, Neil
ORCID: McNaughton, Neil
Gray, Jeffrey A.
Venue: Journal of Affective Disorders
Publisher: Elsevier BV
Published: 2000-12
Volume: 61
Issue: 3
Pages: 161-176
ISSN: 0165-0327 (ISSN-L)
DOI: 10.1016/s0165-0327(00)00344-x
OpenAlex: W2056637988
Cited by: 553
References: 43
Citations by year: 2026: 23 · 2025: 32 · 2024: 22 · 2023: 24 · 2022: 33 · 2021: 37 · 2020: 24 · 2019: 17 · 2018: 28 · 2017: 20 · 2016: 25 · 2015: 25 · 2014: 26 · 2013: 34 · 2012: 13
FWCI: 3.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Affective Disorders (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: anxiolytics, behavioral inhibition system, septo-hippocampal system, hippocampal theta activity, arousal, anxiety
MeSH terms: Amygdala, Animals, Anxiety Disorders, Arousal, Feedback, Hippocampus, Humans, Neural Inhibition, Neural Pathways, Septum Pellucidum, Theta Rhythm, Anti-Anxiety Agents

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Anxiolytic action on the behavioural inhibition system implies multiple types of arousal contribute to anxiety

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks