Cited by 941Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and Applications

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Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability

Anderson, Ian M.·2000·Journal of Affective Disorders

DOI 10.1016/s0165-0327(99)00092-0

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Abstract

Background A meta-analysis of the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) against tricyclic antidepressants (TCAs) in depressed patients was carried out. Methods Efficacy data from 102 randomised controlled trials (10706 patients) were pooled to provide a summary variance-weighted effect size. Tolerability data from 95 studies (10553 patients) were combined to give variance-weighted relative risk of drop out for all reasons and for adverse effects from each study. The effect of age, treatment setting, severity and TCA dose were examined as well as the performance of individual SSRIs and TCAs where there were sufficient studies. Results There is no overall difference in efficacy between SSRIs and TCAs (effect size -0.03, 95% confidence interval -0.09 to 0.03). TCAs do appear more effective in in-patients (-0.23, -0.40 to -0.05) and amitriptyline is more effective than SSRI comparators (-0.14, -0.25 to -0.03) but publication bias cannot be excluded. The SSRIs are better tolerated, with significantly lower rates of treatment discontinuations overall (relative risk 0.88, 0.83 to 0.93; number needed to treat 26) and due to side effects (0.73, 0.67 to 0.80; number needed to treat 33). Individual SSRIs show a similar advantage except for fluvoxamine which does not differ from the TCAs. Individual TCAs show a similar disadvantage in tolerability compared to SSRIs except for dothiepin against which SSRI treatment results in more side-effect related…

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Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Book Reviews: Statistical Methods for Meta-Analysis Larry V. Hedges and Ingram Olkin New York: Academic Press, 1985. xxii + 369 pp
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
Research Diagnostic Criteria
Spitzer, R. L. (1978) · Archives of General Psychiatry · doi:10.1001/archpsyc.1978.01770300115013 · Cited by 6,946
Diagnostic criteria for use in psychiatric research.
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G., & Munoz, R. A. (1972) · Archives of General Psychiatry · doi:10.1001/archpsyc.1972.01750190059011 · Cited by 5,491
Statistical Methods for Meta-Analysis.
Freeman, P. R., Hedges, L. V., & Olkin, I. (1986) · Biometrics · doi:10.2307/2531069 · Cited by 4,840
Research Diagnostic Criteria
Spitzer, R. L., Endicott, J., & Robins, E. (1978) · PsycTESTS Dataset · doi:10.1037/t04137-000 · Cited by 556
Recognition and management of depression in general practice: consensus statement
Paykel, E. S., & Priest, R. G. (1992) · BMJ · doi:10.1136/bmj.305.6863.1198 · Cited by 540
Selective serotonin reuptake inhibitors: meta-analysis of efficacy and acceptability.
Song, F., Freemantle, N., Sheldon, T. A., House, A., Watson, P., Long, A., & Mason, J. (1993) · BMJ · doi:10.1136/bmj.306.6879.683 · Cited by 399
Paroxetine: A selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study
Danish University Antidepressant Group (1990) · Journal of Affective Disorders · doi:10.1016/0165-0327(90)90081-i · Cited by 398

Show all 159 references

Research works printed but not linked: 14

Amin, 1984, Fluvoxamine: antidepressant effects confirmed in a placebo-controlled international study, Clin. Neuropharmacol., 7, S316
Anderson, 1998, A meta-analysis of controlled trials comparing SSRIs in the treatment of depression, J. Psychopharmacol., 12, A20
Dowling, 1990, Fluoxetine: a comparative study with dothiepin, Irish J. Psychiatry, Spring, 3
1993, The treatment of depression in primary care, Effective Health Care Bull., 5, 1
Fawcett, 1989, Fluoxetine versus amitriptyline in adult out-patients with major depression, Curr. Ther. Res., 45, 821
Ginestet, 1989, Fluoxetine in endogenous depression melancholia versus clomipramine, Int. Clin. Psychopharmacol., 4, 37
Harris, 1991, Fluvoxamine versus amitriptyline in depressed hospital out-patients: A multicentre double-blind comparative trial, Br. J. Clin. Res., 2, 89
Hutchinson, 1991, A double blind study in general practice to compare the efficacy and tolerability of paroxetine and amitriptyline in depressed elderly patients, Br. J. Clin. Res., 2, 43
Masco, 1985, Double-blind comparison of fluoxetine and amitriptyline in the treatment of major depressive illness, Adv. Ther., 2, 275
Pakesch, 1991, Depressive syndrome in a clinical trial with private practitioners. [German] OT – Wirkung und Sicherheit von Fluoxetin versus Clomipramin bei ambulanten Patienten mit einem depressiven Syndrom in einer klinischen Prufung bei niedergelassenen Arzten, Wien. Klin. Wochenschr., 103, 176
Pélicier, 1993, Etude multicentrique en double aveugle comparant l’efficacité et la tolerance de la paroxetine et de la clomipramine dans la dépression réactionnelle du sujet âgé, L’Encéphale, XIX, 257
Peters, 1990, Therapy of depression in the psychiatrist’s office – A double-blind multicenter study, Nervenheilkunde, 9, 28
Remick, 1989, A comparison between fluoxetine and doxepin in depressed patients, Curr. Ther. Res., 46, 842
Taneri, 1989, Fluoxetine versus nomifensine in out-patients with neurotic or reactive depression disorder, Int. Clin. Psychopharmacol., 4, 56

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Authors: Anderson, I. M.
Affiliations: University of Manchester (GB)
Corresponding author: Anderson, Ian M.
ORCID: Anderson, Ian M.
Venue: Journal of Affective Disorders
Publisher: Elsevier BV
Published: 2000-04
Volume: 58
Issue: 1
Pages: 19-36
ISSN: 0165-0327 (ISSN-L)
DOI: 10.1016/s0165-0327(99)00092-0
OpenAlex: W2101963851
Cited by: 940
References: 159
Citations by year: 2026: 9 · 2025: 11 · 2024: 29 · 2023: 22 · 2022: 19 · 2021: 13 · 2020: 175 · 2019: 18 · 2018: 26 · 2017: 34 · 2016: 23 · 2015: 35 · 2014: 44 · 2013: 36 · 2012: 52
FWCI: 4.28
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Affective Disorders (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: selective serotonin reuptake inhibitors, tricyclic antidepressants, depression, antidepressant efficacy, antidepressant tolerability, treatment discontinuation, adverse drug reactions, amitriptyline, fluvoxamine, dothiepin, inpatient care, publication bias
MeSH terms: Antidepressive Agents, Tricyclic, Depressive Disorder, Humans, Randomized Controlled Trials as Topic, Treatment Outcome, Selective Serotonin Reuptake Inhibitors, Antidepressive Agents, Second-Generation

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Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability

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