Neuropsychological performance in medicated vs. unmedicated patients with obsessive–compulsive disorder
Abstract
To date, there have been no formal investigations of neuropsychological performance in patients with obsessive-compulsive disorder (OCD) taking psychotropic medications. The purpose of this study was to determine whether medicated and unmedicated patients with OCD demonstrate differences in neuropsychological functioning. Fifty-two patients with a primary DSM-IV diagnosis of OCD participated in the study; 28 were taking serotonin reuptake inhibitors (SRIs), and 24 were treatment-naïve (n=8) or had finished a washout period prior to their inclusion in other studies (n=16). The groups were well matched with regard to demographic and clinical variables, including symptom severity. Each group was administered a comprehensive neuropsychological battery to assess general intelligence, attention, verbal and non-verbal working memory, declarative and procedural learning, visuo-constructive skills, and executive functions. SRI-medicated did not differ from SRI-free patients on any neuropsychological measure. Benzodiazepines seemed to improve the patients' functioning on a semantic verbal fluency test. In addition, there were significant interactions between SRIs and benzodiazepines on the perseverative errors of the Wisconsin Card Sorting Test and on reaction times. SRI-medicated patients with OCD are able to perform on cognitive functioning tests at a comparable level with that of SRI-free patients, and these results have positive implications for OCD patients who respond to SRIs. The interactions between SRIs and benzodiazepines and their effect on cognition in OCD are likely to be complex and deserve further study.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Some studies have suggested that medication may not influence cognitive function or group differences in activation.
“Some studies have suggested that medication may not influence cognitive function or group differences in activation.6,50”
From Cognitive inflexibility and frontal–cortical activation in pediatric obsessive–compulsive disorder (2010) · cites this paper as [50]
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712 · see citing works
(1995) · Cited by 2,809 · see citing works
Deficits on subject-ordered tasks after frontal- and temporal-lobe lesions in man
Petrides, M., & Milner, B. A. (1982) · Neuropsychologia · doi:10.1016/0028-3932(82)90100-2 · Cited by 1,272 · see citing works
The functional equivalence of problem solving skills
Simon, H. A. (1975) · Cognitive Psychology · doi:10.1016/0010-0285(75)90012-2 · Cited by 737 · see citing works
Cornblatt, B. A., Risch, N. J., Faris, G., Friedman, D., & Erlenmeyer-Kimling, L. (1988) · Psychiatry Research · doi:10.1016/0165-1781(88)90076-5 · Cited by 682 · see citing works
A 40-Year Follow-up of Patients With Obsessive-compulsive Disorder
Skoog, G., & Skoog, I. G. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.2.121 · Cited by 634 · see citing works
Modell, J. G., Mountz, J. M., Curtis, G. C., & Greden, J. F. (1989) · Journal of Neuropsychiatry · doi:10.1176/jnp.1.1.27 · Cited by 425 · see citing works
Organizational strategies mediate nonverbal memory impairment in obsessive–compulsive disorder
Savage, C. R., Baer, L., Keuthen, N. J., Brown, H. D., Rauch, S. L., & Jenike, M. A. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00278-9 · Cited by 423 · see citing works
Cognitive Deficits in Obsessive–Compulsive Disorder on Tests of Frontal–Striatal Function
Purcell, R., Maruff, P., Kyrios, M., & Pantelis, C. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00201-1 · Cited by 313 · see citing works
Strategic processing and episodic memory impairment in obsessive compulsive disorder.
Savage, C. R., Deckersbach, T., Wilhelm, S., Rauch, S. L., Baer, L., Reid, T., & Jenike, M. A. (2000) · Neuropsychology · doi:10.1037//0894-4105.14.1.141 · Cited by 269 · see citing works
Neuropyschological performance in obsessive-compulsive disorder
Christensen, K. J., Kim, S. W., Dysken, M. W., & Hoover, K. M. (1992) · Biological Psychiatry · doi:10.1016/0006-3223(92)90003-i · Cited by 256 · see citing works
Deficit in cognitive shifting ability in patients with obsessive-compulsive disorder
Head, D., Bolton, D., & Hymas, N. (1989) · Biological Psychiatry · doi:10.1016/0006-3223(89)90272-2 · Cited by 215 · see citing works
Strategic processing and episodic memory impairment in obsessive compulsive disorder.
Savage, C. R., Deckersbach, T., Wilhelm, S., et al. (2000) · Neuropsychology · doi:10.1037/0894-4105.14.1.141 · Cited by 213 · see citing works
Obsessive-Compulsive Disorders: Theory and Management
Jenike, M. A., Baer, L., & Minichiello, W. E. (1986) · Medical Entomology and Zoology · Cited by 205 · see citing works
Current status of pharmacological and behavioral treatment of obsessive-compulsive disorder
Stanley, M. A., & Turner, S. M. (1995) · Behavior Therapy · doi:10.1016/s0005-7894(05)80089-9 · Cited by 172 · see citing works
Obsessive-Compulsive Disorders: Theory and Management
Zohar, J. (1987) · Psychosomatics · doi:10.1016/s0033-3182(87)72473-6 · Cited by 141 · see citing works
Obsessive compulsive disorder and basal ganglia dysfunction
Rapoport, J. L. (1990) · Psychological Medicine · doi:10.1017/s0033291700016962 · Cited by 130 · see citing works
Obsessive Compulsive Disorders
(2007) · David Fulton Publishers eBooks · doi:10.4324/9780203935217-12 · Cited by 122 · see citing works
Schmitt, J. A. J., Kruizinga, M. J., & Riedel, W. J. (2001) · Journal of Psychopharmacology · doi:10.1177/026988110101500304 · Cited by 114 · see citing works
Beers, S. R., Rosenberg, D. R., Dick, E. L., Williams, T., O’Hearn, K. M., Birmaher, B. B., & Ryan, C. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.777 · Cited by 91 · see citing works
(1991) · PubMed · Cited by 66 · see citing works
Working memory as assessed by subject-ordered tasks in patients with obsessive-compulsive disorderxs
Martin, A. D., Wiggs, C. L., Altemus, M. M., Rubenstein, C., & Murphy, D. L. (1995) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639508405167 · Cited by 63 · see citing works
Obsessive-Compulsive Disorders: Practical Management, 3rd ed.
Black, D. W. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.509 · Cited by 52 · see citing works
Allen, D., Curran, H. V., & Lader, M. (1991) · European Journal of Clinical Pharmacology · doi:10.1007/bf00265843 · Cited by 51 · see citing works
Fudge, J. L., Perry, P. J., Garvey, M. J., & Kelly, M. W. (1990) · Journal of Affective Disorders · doi:10.1016/0165-0327(90)90079-n · Cited by 49 · see citing works
Richardson, J. S., Keegan, D. L., Bowen, R. C., Blackshaw, S. L., Cebrian-Perez, S., Dayal, N., Saleh, S., & Shrikhande, S. (1994) · International Clinical Psychopharmacology · doi:10.1097/00004850-199400910-00006 · Cited by 45 · see citing works
Desai, N., Taylor‐Davies, A., & Barnett, D. (1983) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1983.tb01486.x · Cited by 45 · see citing works
Effects of Antidepressants on Human Performance: A Review
Deptula, D., & Pomara, N. (1990) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199004000-00005 · Cited by 45 · see citing works
The effects of sertraline on psychomotor performance in elderly volunteers.
Hindmarch, I., Shillingford, J.-A., & SHILLINGFORD, C. A. (1990) · PubMed · Cited by 41 · see citing works
The effects on performance of two antidepressants, alone and in combination with diazepam
Moskowitz, H., & Burns, M. M. (1988) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(88)90023-1 · Cited by 35 · see citing works
Fluoxetine-Induced Memory Impairment in an Adolescent
Bangs, M. E., Petti, T. A., & Janus, M. (1994) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199411000-00012 · Cited by 33 · see citing works
Cognitive dysfunction associated with fluoxetine
Mirow, S. (1991) · American Journal of Psychiatry · doi:10.1176/ajp.148.7.948 · Cited by 31 · see citing works
Bartfai, A., Åsberg, M., Mårtensson, B., & Gustavsson, P. J. (1991) · Biological Psychiatry · doi:10.1016/0006-3223(91)90179-p · Cited by 26 · see citing works
Reduced Design Fluency in Subclinical Obsessive-Compulsive Subjects
Mataix‐Cols, D., Barrios, M., Sánchez‐Turet, M., Vallejo, J., & Junqué, C. (1999) · Journal of Neuropsychiatry · doi:10.1176/jnp.11.3.395 · Cited by 24 · see citing works
Self-citationFluoxetine and Memory Impairment
Bradley, S. J., & Kulik, L. (1993) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199309000-00034 · Cited by 17 · see citing works
Neuroimagen y neuropsicología del trastorno obsesivo-compulsivo: avances recientes
Mataix‐Cols, D. (2001) · Psiquiatría Biológica · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Menzies, L., Chamberlain, S. R., Laird, A. R., Thelen, S. M., Sahakian, B. J., & Bullmore, E. T. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.09.005 · Cited by 1,190 · see citing works
Anxiety and working memory capacity: A meta-analysis and narrative review.
Moran, T. P. (2016) · Psychological Bulletin · doi:10.1037/bul0000051 · Cited by 776 · see citing works
A review on cognitive impairments in depressive and anxiety disorders with a focus on young adults
Castaneda, A. E., Tuulio‐Henriksson, A., MARTTUNEN, M. J., Suvisaari, J., & Lönnqvist, J. K. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.06.006 · Cited by 755 · see citing works
The neuropsychology of adult obsessive–compulsive disorder: A meta-analysis
Abramovitch, A., Abramowitz, J. S., & Mittelman, A. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2013.09.004 · Cited by 444 · see citing works
Neuropsychological performance in obsessive-compulsive disorder: a critical review
Kuelz, A. K., Hohagen, F., & Voderholzer, U. (2004) · Biological Psychology · doi:10.1016/j.biopsycho.2003.07.007 · Cited by 436 · see citing works
Impaired response inhibition in obsessive compulsive disorder
Penadés, R., Catalán, R., Rubia, K., Andrés, S., Salamero, M., & Gastó, C. (2007) · European Psychiatry · doi:10.1016/j.eurpsy.2006.05.001 · Cited by 308 · see citing works
Lawrence, N. S., Wooderson, S., Mataix-Cols, D., David, R., Speckens, A., & Phillips, M. L. (2006) · Neuropsychology · doi:10.1037/0894-4105.20.4.409 · Cited by 291 · see citing works
Self-citationMemory and executive functioning in obsessive–compulsive disorder: A selective review
Olley, A., Malhi, G., & Sachdev, P. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.02.023 · Cited by 249 · see citing works
A neuropsychological comparison of obsessive–compulsive disorder and trichotillomania
Chamberlain, S. R., Fineberg, N. A., Blackwell, A. D., Clark, L., Robbins, T. W., & Sahakian, B. J. (2007) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.07.016 · Cited by 212 · see citing works
Roth, R. M., Saykin, A. J., Flashman, L. A., Pixley, H. S., West, J. D., & Mamourian, A. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.007 · Cited by 181 · see citing works
Neurobiology of Obsessive-Compulsive Disorder:<i>Serotonin and Beyond</i>
Westenberg, H. G. M., Fineberg, N. A., & Denys, D. (2007) · CNS Spectrums · doi:10.1017/s1092852900002479 · Cited by 148 · see citing works
Nakao, T., Nakagawa, A., Nakatani, E., Nabeyama, M., Sanematsu, H., Yoshiura, T., Togao, O., Tomita, M., Masuda, Y., Yoshioka, K., et al. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2008.10.013 · Cited by 149 · see citing works
Are neuropsychological deficits trait markers in OCD?
Rao, N. P., Reddy, Y. C. J., Kumar, K. J., Kandavel, T., & Chandrashekar, C. R. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.05.026 · Cited by 136 · see citing works
The cognitive neuropsychology of obsessive-compulsive disorder: a critical review
Abramovitch, A., & Cooperman, A. (2015) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2015.01.002 · Cited by 126 · see citing works
Göttlich, M., Krämer, U. M., Kordon, A., Hohagen, F., & Zurowski, B. (2014) · Human Brain Mapping · doi:10.1002/hbm.22574 · Cited by 116 · see citing works
The neurobiological link between OCD and ADHD
Brem, S., Grünblatt, E., Drechsler, R., Riederer, P., & Walitza, S. (2014) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-014-0146-x · Cited by 109 · see citing works
Melloni, M., Urbistondo, C., Sedeño, L., Gelormini‐Lezama, C., Kichic, R., & Ibáñez, A. M. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00259 · Cited by 108 · see citing works
Dissociation of decisions in ambiguous and risky situations in obsessive–compulsive disorder
Starcke, K., Tuschen-Caffier, B., Markowitsch, H. J., & Brand, M. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2008.10.022 · Cited by 105 · see citing works
Aycicegi, A., Dinn, W. M., Harris, C. L., & Erkmen, H. (2003) · European Psychiatry · doi:10.1016/s0924-9338(03)00065-8 · Cited by 105 · see citing works
Kashyap, H., Kumar, J. K., Kandavel, T., & Reddy, Y. C. J. (2013) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2012.12.003 · Cited by 104 · see citing works
Are there reliable neuropsychological deficits in obsessive–compulsive disorder?
Simpson, H. B., Rosen, W. G., Huppert, J. D., Lin, S., Foa, E. B., & Liebowitz, M. R. (2005) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2005.04.004 · Cited by 96 · see citing works
Motor inhibition in trichotillomania and obsessive–compulsive disorder
Bohne, A., Savage, C. R., Deckersbach, T., Keuthen, N. J., & Wilhelm, S. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.11.008 · Cited by 97 · see citing works
Fradkin, I., Adams, R. A., Parr, T., Roiser, J. P., & Huppert, J. D. (2020) · Psychological Review · doi:10.1037/rev0000188 · Cited by 89 · see citing works
Bohne, A., Savage, C. R., Deckersbach, T., Keuthen, N. J., Jenike, M. A., Tuschen‐Caffier, B., & Wilhelm, S. (2005) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390490520418 · Cited by 95 · see citing works
Cognitive inflexibility and frontal–cortical activation in pediatric obsessive–compulsive disorder
Britton, J. C., Rauch, S. L., Rosso, I. M., Killgore, W. D. S., Price, L. M., Ragan, J., Chosak, A., Hezel, D. M., Pine, D. S., Leibenluft, E., et al. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.05.006 · Cited by 92 · see citing works
Tümkaya, S., Karadağ, F., Oğuzhanoğlu, N. K., Tekkanat, Ç., Varma, G. S., Özdel, O. İ., & Ateşçi, F. Ç. (2008) · Psychiatry Research · doi:10.1016/j.psychres.2007.07.031 · Cited by 90 · see citing works
Neuropsychological function in obsessive-compulsive disorder
Tükel, R., Gürvit, H., Ertekin, B. A., Oflaz, S., Ertekin, E., Baran, B., Kalem, Ş. A., Kandemir, P. E., Özdemiroğlu, F. A., & Atalay, F. (2012) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2011.03.007 · Cited by 89 · see citing works
Amitai Abramovitch, A., Dar, R., Schweiger, A., & Hermesh, H. (2011) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acr022 · Cited by 80 · see citing works
A study of neuropsychological deficit in children with obsessive-compulsive disorder
Shin, M.-S., Choi, H., Kim, H., Hwang, J.-W., Kim, B.-N., & Cho, S.-C. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2008.03.010 · Cited by 81 · see citing works
Andrés, S., Boget, T., Lázaro, L., Penadés, R., Morer, Á., Salamero, M., & Castro‐Fornieles, J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.027 · Cited by 81 · see citing works
Omori, I. M., Murata, Y., Yamanishi, T., Nakaaki, S., Akechi, T., Mikuni, M., & Furukawa, T. A. (2007) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.05.005 · Cited by 74 · see citing works
Göttlich, M., Krämer, U. M., Kordon, A., Hohagen, F., & Zurowski, B. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.09.004 · Cited by 73 · see citing works
Neuropsychological performance in OCD: A study in medication-naïve patients
Krishna, R., Udupa, S., George, C. M., Kumar, K. J., Viswanath, B., Kandavel, T., Venkatasubramanian, G., & Reddy, Y. C. J. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.09.009 · Cited by 69 · see citing works
Episodic Memories in Anxiety Disorders: Clinical Implications
Zlomuzica, A., Dere, D., Machulska, A., Adolph, D., Dere, E., & Margraf, J. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00131 · Cited by 66 · see citing works
Leopold, R., & Backenstrass, M. (2015) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2014.12.016 · Cited by 63 · see citing works
Bedard, M.-J., Joyal, C. C., Godbout, L., & Chantal, S. (2009) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acp052 · Cited by 62 · see citing works
Segalàs, C., Alonso, P., Labad, J., Jaurrieta, N., Real, E., Jiménez, S., Menchón, J. M., & Vallejo, J. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.2.262 · Cited by 61 · see citing works
Self-citationHenseler, I., Gruber, O., Kraft, S., Krick, C., Reith, W., & Falkai, P. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0821 · Cited by 61 · see citing works
Cognitive inhibition in trichotillomania and obsessive–compulsive disorder
Bohne, A., Keuthen, N. J., Tuschen-Caffier, B., & Wilhelm, S. (2005) · Behaviour Research and Therapy · doi:10.1016/j.brat.2004.06.014 · Cited by 58 · see citing works
Jaafari, N., Frasca, M., Rigalleau, F., Rachid, F., Gil, R., Olié, J.-P., Guehl, D., Burbaud, P., Aouizerate, B., Rotgé, J.-Y., et al. (2013) · European Psychiatry · doi:10.1016/j.eurpsy.2011.07.001 · Cited by 58 · see citing works
Abramovitch, A., Mittelman, A., Tankersley, A. P., Abramowitz, J. S., & Schweiger, A. (2015) · Psychiatry Research · doi:10.1016/j.psychres.2015.04.025 · Cited by 56 · see citing works
Lewin, A. B., Larson, M. J., Park, J. M., Mcguire, J. F., Murphy, T. K., & Storch, E. A. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.01.014 · Cited by 53 · see citing works
Rao, N. P., Arasappa, R., Reddy, N. N., Venkatasubramanian, G., & Reddy, Y. C. J. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2009.10.017 · Cited by 53 · see citing works
Relation of Neurological Soft Signs to Nonverbal Memory Performance in Obsessive-Compulsive Disorder
Mataix‐Cols, D., Alonso, P., Hernández, R., Deckersbach, T., Savage, C. R., Menchón, J. M., & Vallejo, J. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.6.842.16470 · Cited by 53 · see citing works
Self-citationMoritz, S., Meier, B., Hand, I., Schick, M., & Jahn, H. (2004) · Psychiatry Research · doi:10.1016/j.psychres.2003.11.003 · Cited by 52 · see citing works
van der Wee, N. J. A., Ramsey, N. F., van Megen, H. J. G. M., Denys, D. A. J. P., Westenberg, H. G. M., & Kahn, R. S. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.04.012 · Cited by 50 · see citing works
Neurocognitive function in paediatric obsessive-compulsive disorder
GELLER, D. A., Amitai Abramovitch, A., Andrew Mittelman, B., Stark, A. M., Ramsey, K. A., Cooperman, A. W., Baer, L., & Stewart, S. E. (2017) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2017.1282173 · Cited by 48 · see citing works
Executive and Attention Functioning Among Children in the PANDAS Subgroup
Hirschtritt, M. E., Hammond, C. J., Luckenbaugh, D. A., Buhle, J. T., Thurm, A. E., Casey, B. J., & Swedo, S. E. (2008) · Child Neuropsychology · doi:10.1080/09297040802186899 · Cited by 42 · see citing works
Rampacher, F., Lennertz, L., Vogeley, A., Schulze‐Rauschenbach, S., Kathmann, N., Falkai, P., & Wagner, M. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.05.008 · Cited by 41 · see citing works
Neurocognitive deficits in obsessive–compulsive disorder: A selective review
Rao, N., & Suhas, S. (2019) · Indian Journal of Psychiatry · doi:10.4103/psychiatry.indianjpsychiatry_517_18 · Cited by 41 · see citing works
Jang, J. H., Kim, H. S., Ha, T. H., Shin, N. Y., Kang, D.-H., Choi, J.-S., Ha, K., & Kwon, J. S. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2010.04.016 · Cited by 36 · see citing works
Procedural and declarative memory in obsessive-compulsive disorder
Roth, R. M., Baribeau, J. M. C., Milovan, D. L., O’Connor, K. P., & Todorov, C. (2004) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617704105018 · Cited by 36 · see citing works
Cognitive and neurobiological findings in obsessive–compulsive disorder
Anderson, K. E., & Savage, C. R. (2004) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(03)00107-2 · Cited by 36 · see citing works
Kalanthroff, E., & Wheaton, M. G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11247379 · Cited by 35 · see citing works
Always on guard: test of high vs. low control conditions in obsessive-compulsive disorder patients
Kalanthroff, E., Anholt, G. E., & Henik, A. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.05.050 · Cited by 34 · see citing works
Neuropsychological impairments in panic disorder: A systematic review
O׳Sullivan, K., & Newman, E. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.06.024 · Cited by 33 · see citing works
Ozcan, H., Ozer, S., & Yagcioglu, S. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.04.013 · Cited by 31 · see citing works
Zhang, L., Dong, Y., Ji, Y., Tao, R., Chen, X., Ye, J., Zhang, L., Yu, F., Zhu, C., & Wang, K. (2015) · Scientific Reports · doi:10.1038/srep17312 · Cited by 26 · see citing works
Apergis-Schoute, A. M., van der Flier, F. E., Ip, S., Kanen, J. W., Vaghi, M. M. S., Fineberg, N. A., Sahakian, B. J., Cardinal, R. N., & Robbins, T. W. (2023) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2023.06.004 · Cited by 26 · see citing works
Remembering and forgetting: directed forgetting effect in obsessive-compulsive disorder
Konishi, Shishikura, Nakaaki, Komatsu, & Mimura (2011) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s21047 · Cited by 26 · see citing works
Ghisi, M., Bottesi, G., Sica, C., Sanavio, E., & Freeston, M. H. (2013) · Cognitive Therapy and Research · doi:10.1007/s10608-013-9560-1 · Cited by 25 · see citing works
Kloft, L., Kischkel, E., Kathmann, N., & Reuter, B. (2010) · Psychophysiology · doi:10.1111/j.1469-8986.2010.01138.x · Cited by 24 · see citing works
[Assessment of executive/attentional performance in Asperger's disorder].
Kılınçaslan, A., Mukaddes, N. M., Küçükyazıcı, G. S., & Gurvit, H. I. (2010) · PubMed · Cited by 24 · see citing works
Do pathological gambling and obsessive-compulsive disorder overlap? a neurocognitive perspective
Hur, J., Shin, N. Y., Kim, S. N., Jang, J. H., Choi, J., Shin, Y.-C., & Kwon, J. S. (2012) · CNS Spectrums · doi:10.1017/s1092852912000545 · Cited by 21 · see citing works
Mataix‐Cols, D., Rahman, Q., Spiller, M. J., Alonso, M. P., Pifarré, J., Menchón, J. M., & Vallejo, J. (2006) · Applied Neuropsychology · doi:10.1207/s15324826an1301_6 · Cited by 23 · see citing works
Self-citationCognitive dysfunction in post-traumatic obsessive–compulsive disorder
Borges, M. C., Braga, D. T., Iêgo, S., D'Alcante, C. C., Sidrim, I., Machado, M. C., Pinto, P. S. P., Cordioli, A. V., do Rosário, M. C., Petribú, K., et al. (2011) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2010.527822 · Cited by 21 · see citing works
Executive functioning and clinical variables in patients with obsessive-compulsive disorder
Martínez-Esparza, I. C., Olivares-Olivares, P. J., Rosa-Alcázar, Á., Rosa-Alcázar, A. I., & Storch, E. A. (2021) · Brain Sciences · doi:10.3390/brainsci11020267 · Cited by 21 · see citing works
Response inhibition in a subclinical obsessive-compulsive sample
Amitai Abramovitch, A., Shaham, N., Levin, L., Bar-Hen, M., & Schweiger, A. (2014) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2014.09.001 · Cited by 21 · see citing works
Olson, C. A., Hale, L. R., Hamilton, N., Powell, J. N., Martin, L. E., & Savage, C. R. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.08.031 · Cited by 17 · see citing works
Situation awareness in obsessive-compulsive disorder
Tümkaya, S., Karadağ, F., Mueller, S. T., Uğurlu, T. T., Oğuzhanoğlu, N. K., Özdel, O. İ., Ateşçi, F. Ç., & Bayraktutan, M. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.02.009 · Cited by 16 · see citing works
Kelmendi, B., Adams, T. G., Jakubovski, E., Hawkins, K. A., Coric, V., & Pittenger, C. (2016) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2016.03.003 · Cited by 16 · see citing works
Moreira, L. V., Bins, H. D. D. C., Torresan, R. C., Ferro, C., Harttmann, T., Petribú, K., Juruena, M. F., do Rosário, M. C., & Ferrão, Y. A. (2012) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.12.004 · Cited by 17 · see citing works
Declarative and Procedural Learning in Individuals With Subclinical Obsessive-Compulsive Symptoms
Mataix‐Cols, D. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.6.830.16477 · Cited by 16 · see citing works
Self-citationKuelz, A. K., Riemann, D. W., Zahn, R., & Voderholzer, U. (2004) · European Psychiatry · doi:10.1016/j.eurpsy.2004.06.016 · Cited by 16 · see citing works
Segalàs, C., Alonso, P., Labad, J., Real, E., Pertusa, A., Jaurrieta, N., Jiménez‐Múrcia, S., Menchón, J. M., & Vallejo, J. (2009) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2009.05.008 · Cited by 15 · see citing works
Self-citationPerna, G., Cavedini, P., Harvey, P. D., Chiaro, N. V. D., Daccò, S., & Caldirola, D. (2016) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651501.2016.1223856 · Cited by 13 · see citing works
Actualización neuropsicológica del trastorno obsesivo-compulsivo
Martínez‐González, A. E., & Piqueras, J. A. (2008) · Revista de Neurología · doi:10.33588/rn.4610.2008064 · Cited by 13 · see citing works
A review of neuroimaging studies of anxiety disorders in China
SHI (2011) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s10997 · Cited by 12 · see citing works
Varinelli, A., Caricasole, V., Pellegrini, L., Hall, N., Garg, K., Mpavaenda, D., Dell’Osso, B., Albert, U., the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) Expert Survey Workgroup, & Fineberg, N. A. (2022) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651501.2021.1872646 · Cited by 9 · see citing works
Perna, G., Cavedini, P., Riva, A., Chiaro, N. V. D., Bellotti, M., Diaferia, G., & Caldirola, D. (2018) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2018.1544888 · Cited by 9 · see citing works
Visual search for verbal material in patients with obsessive–compulsive disorder
Botta, F., Vibert, N., Harika‐Germaneau, G., Frasca, M., Rigalleau, F., Fakra, É., Ros, C., Rouet, J., Ferreri, F., & Jaafari, N. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.03.054 · Cited by 9 · see citing works
Neuropsychology of obsessive-compulsive disorder
Deckersbach, T., Savage, C. R., & Rauch, S. L. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511642197.028 · Cited by 8 · see citing works
Doolub, D., Vibert, N., Botta, F., Razmkon, A., Bouquet, C., Wassouf, I., Millet, B., Harika-Germaneau, G., & Jaafari, N. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1017206 · Cited by 7 · see citing works
Doolub, D., Vibert, N., Botta, F., Razmkon, A., Bouquet, C. A., Wassouf, I., Millet, B., Harika-Germaneau, G., & Jaafari, N. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.04.052 · Cited by 5 · see citing works
Neuropsychological deficits in drug naïve, non-depressed obsessive-compulsive disorder patients
Roopesh, B. N., Reddy, Y. C. J., & Mukundan, C. R. (2012) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2012.10.003 · Cited by 7 · see citing works
Löchner, C., Chamberlain, S. R., Kidd, M., Taljaard, L., Fineberg, N. A., Robbins, T. W., & Stein, D. J. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05597-7 · Cited by 6 · see citing works
Involuntary social cue integration in patients with obsessive compulsive disorder
Tümkaya, S., Karadağ, F., Jellema, T., Oğuzhanoğlu, N. K., Özdel, O. İ., Ateşçi, F. Ç., & Varma, G. S. (2013) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.08.007 · Cited by 6 · see citing works
Mueller, S. M. (2014) · International Neuropsychiatric Disease Journal · doi:10.9734/indj/2014/8102 · Cited by 6 · see citing works
Bottesi, G., & Ghisi, M. (2014) · Psychopathology Review · doi:10.5127/pr.032713 · Cited by 5 · see citing works
Capsulotomy in anxiety disorders
Rück, C. (2006) · Cited by 6 · see citing works
Neuropsychological performance in youth with obsessive-compulsive disorder
Deepthi, K., Roopesh, B. N., Balachander, S., Sagar, J. V., Thennarasu, K., & Reddy, Y. C. J. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.03.066 · Cited by 4 · see citing works
Kathmann, N., Bogdahn, B., & Endraß, T. (2013) · Journal of Experimental Psychopathology · doi:10.5127/jep.031512 · Cited by 3 · see citing works
Obsessive-compulsive disorder: towards better understanding and outcomes
Kirkby, K. C. (2003) · Current Opinion in Psychiatry · doi:10.1097/00001504-200301000-00011 · Cited by 3 · see citing works
Neuropsychological Assessment of Obsessive–Compulsive Disorder
Brand, J., Reid, J. M., & McKay, D. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6452-5_4 · Cited by 3 · see citing works
Functional imaging of obsessive–compulsive disorder
Gu, B.-M., Kang, D., & Kwon, J. S. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511782091.018 · Cited by 2 · see citing works
Obsesif Kompulsif Bozuklukta Bilişsel İşlevler
Aydin, P. Ç., & Güleç, D. (2013) · Cited by 2 · see citing works
Tsuruta, Y., Iwamoto, K., Banno, M., Kawano, N., Kohmura, K., Miyata, S., Fujishiro, H., Noda, Y., Noda, A., Iritani, S., et al. (2018) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.2678 · Cited by 2 · see citing works
Durán, E. T., Ricardo-Garcell, J., Reyes-Zamorano, E., & Lóyzaga, C. (2007) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 2 · see citing works
Herreras, E. B. (2010) · Archivos de Neurociencias · Cited by 1 · see citing works
Mukai, K., Matsuura, N., Nakajima, A., Yanagisawa, Y., Yoshida, Y., Maebayashi, K., Hayashida, K., & Matsunaga, H. (2017) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2017.01.010 · Cited by 1 · see citing works
- Authors
- Mataix-Cols, D., Alonso, P., Pifarré, J., Menchón, J. M., & Vallejo, J.
- Affiliations
- Bellvitge University Hospital (ES)
- Hospital Universitari de Santa Maria (ES)
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2002-04
- Volume
- 109
- Issue
- 3
- Pages
- 255-264
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W1979451759
- Cited by
- 116
- References
- 37
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 5 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 10 · 2013: 11 · 2012: 4
- FWCI
- 6.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Psychological Association
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- obsessive-compulsive disorder, neuropsychological performance, serotonin reuptake inhibitors, benzodiazepines, working memory, executive function, verbal fluency, Wisconsin Card Sorting Test, reaction time, treatment-naive patients
- MeSH terms
- Adult, Benzodiazepines, Drug Therapy, Combination, Female, Humans, Male, Neuropsychological Tests, Obsessive-Compulsive Disorder, Antipsychotic Agents, Anti-Anxiety Agents, Selective Serotonin Reuptake Inhibitors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
