Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

Ghosh, S., May, M. J., & Kopp, E. B. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.225 · Cited by 5,182

Brain corticosteroid receptor balance in health and disease

de Kloet, E. R., Vreugdenhil, E., Oitzl, M. S., & Joëls, M. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.3.0331 · Cited by 2,614

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

Auphan, N., DiDonato, J. A., Rosette, C., Helmberg, A., & Karin, M. (1995) · Science · doi:10.1126/science.270.5234.286 · Cited by 2,390

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

Kamei, Y., Xu, L., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S.-C., Heyman, R. A., Rose, D. W., Glass, C. K., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81118-6 · Cited by 2,150

Steroid hormone receptors: Many Actors in search of a plot

Beato, M., Herrlich, P. A., & Schütz, G. (1995) · Cell · doi:10.1016/0092-8674(95)90201-5 · Cited by 1,816

Role of Transcriptional Activation of IκBα in Mediation of Immunosuppression by Glucocorticoids

Scheinman, R. I., Cogswell, P. C., Lofquist, A. K., & Baldwin, A. S. (1995) · Science · doi:10.1126/science.270.5234.283 · Cited by 1,676

Anti-inflammatory Actions of Glucocorticoids: Molecular Mechanisms

Barnes, P. J. (1998) · Clinical Science · doi:10.1042/cs0940557 · Cited by 1,591

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

Jonat, C., Rahmsdorf, H. J., Park, K.-K., Cato, A. C. B., Gebel, S., Ponta, H., & Herrlich, P. (1990) · Cell · doi:10.1016/0092-8674(90)90395-u · Cited by 1,544

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

Zhong, H., Voll, R. E., & Ghosh, S. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80066-0 · Cited by 1,210

Use of immunosuppressive agents in uveitis

Lustig, M. J., & Cunningham, E. T. (2003) · Current Opinion in Ophthalmology · doi:10.1097/00055735-200312000-00014 · Cited by 43

Proteomic evaluation of pathways associated with dexamethasone‐mediated apoptosis and resistance in multiple myeloma

Rees‐Unwin, K. S., Craven, R. A., Davenport, E. L., Hanrahan, S. J., Totty, N. F., Dring, A. M., Banks, R. E., Morgan, G. J., & Davies, F. E. (2007) · British Journal of Haematology · doi:10.1111/j.1365-2141.2007.06837.x · Cited by 43

Current Therapies for Neonatal Hypoxic–Ischaemic and Infection-Sensitised Hypoxic–Ischaemic Brain Damage

Tetorou, K., Sisa, C., Iqbal, A., Dhillon, K., & Hristova, M. (2021) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2021.709301 · Cited by 43

Enhanced Expression of CD20 in Human Tumor B Cells Is Controlled through ERK-Dependent Mechanisms

Wojciechowski, W., Li, H., Marshall, S. A., Dell’Agnola, C., & Espinoza‐Delgado, I. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.12.7859 · Cited by 42

The Role of Steroid Hormones in the Modulation of Neuroinflammation by Dietary Interventions

Vasconcelos, A. R., Cabral‐Costa, J. V., Mazucanti, C. H., Scavone, C., & Kawamoto, E. M. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00009 · Cited by 41

α Actinin 4 (ACTN4) Regulates Glucocorticoid Receptor-mediated Transactivation and Transrepression in Podocytes

Zhao, X., Khurana, S., Charkraborty, S., Tian, Y., Sedor, J. R., Bruggman, L. A., & Kao, H. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.755546 · Cited by 42

Beta-2 Adrenergic and Glucocorticoid Receptor Agonists Modulate Ozone-Induced Pulmonary Protein Leakage and Inflammation in Healthy and Adrenalectomized Rats

Henriquez, A. R., Snow, S. J., Schladweiler, M. C. J., Miller, C. N., Dye, J. A., Ledbetter, A. D., Richards, J. H., McGee, M. A., Williams, W. C., & Kodavanti, U. P. (2018) · Toxicological Sciences · doi:10.1093/toxsci/kfy198 · Cited by 39

Endothelial cells of the blood-brain barrier: a target for glucocorticoids and estrogens?

Dietrich, J. (2004) · Frontiers in bioscience · doi:10.2741/1272 · Cited by 40

Glucocorticoids mediate differential anti‐apoptotic effects in human fibroblasts and keratinocytes via sphingosine‐1‐phosphate formation

Hammer, S., Sauer, B., Spika, I., Schraut, C., Kleuser, B., & Schäfer‐Korting, M. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10766 · Cited by 40

The glucocorticoid receptor is a co‐regulator of the orphan nuclear receptor Nurr1

Carpentier, R., Sacchetti, P., Ségard, P., Staels, B., & Lefèbvre, P. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05055.x · Cited by 39

Ganoderma lucidum aqueous extract prevents hypobaric hypoxia induced memory deficit by modulating neurotransmission, neuroplasticity and maintaining redox homeostasis

Sharma, P., & Tulsawani, R. (2020) · Scientific Reports · doi:10.1038/s41598-020-65812-5 · Cited by 38

Glucocorticoids and Central Nervous System Inflammation

Dinkel, K., Ogle, W. O., & Sapolsky, R. M. (2002) · Journal of NeuroVirology · doi:10.1080/13550280290100914 · Cited by 38

The Impact of Intramammary Escherichia coli Challenge on Liver and Mammary Transcriptome and Cross-Talk in Dairy Cows during Early Lactation Using RNAseq

Moyes, K. M., Sørensen, P. B., & Bionaz, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157480 · Cited by 36

Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells

Sohn, K., Jang, S., Choi, D.-K., Lee, Y., Yoon, T., Jeon, E. K., Kim, K. H., Seo, Y., Lee, J., Park, J.-K., et al. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.03.065 · Cited by 34

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL

Chonghaile, T. N., Concannon, C. G., Szegezdi, É., Gorman, A. M., & Afshin Samali, A. (2006) · APOPTOSIS · doi:10.1007/s10495-006-7233-1 · Cited by 33

Drug choices in autoimmune hepatitis: Part A – steroids

Czaja, A. J. (2012) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.12.40 · Cited by 33

Emerging Opportunities for Site-Specific Molecular and Cellular Interventions in Autoimmune Hepatitis

Czaja, A. J. (2010) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-1122-8 · Cited by 30

Targeting Hepatic Fibrosis in Autoimmune Hepatitis

Montaño‐Loza, A. J., Thandassery, R. B., & Czaja, A. J. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4254-7 · Cited by 30

The Promoter Context Determines Mutual Repression or Synergism between NF-κB and the Glucocorticoid Receptor

Hofmann, T. G., & Schmitz, M. L. (2002) · Biological Chemistry · doi:10.1515/bc.2002.219 · Cited by 30

Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium

Crisafulli, U., Xavier, A. M., dos Santos, F. B., Cambiaghi, T. D., Chang, S. Y., Porcionatto, M. A., Castilho, B. A., Malnic, B., & Glezer, I. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00050 · Cited by 28

Effects of orally administered cortisol and norepinephrine on weanling piglet gut microbial populations and Salmonella passage1

Petrosus, E. M., Silva, E. B., Lay, D. C., & Eicher, S. D. (2018) · Journal of Animal Science · doi:10.1093/jas/sky312 · Cited by 29

Molecular mechanisms for corticotropin-releasing hormone gene repression by glucocorticoid in BE(2)C neuronal cell line

Yamamori, E., Iwasaki, Y., Taguchi, T., Nishiyama, M., Yoshida, M., Asai, M., Oiso, Y., Itoi, K., Kambayashi, M., & Hashimoto, K. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.11.001 · Cited by 29

Estrogen Receptor Antagonist Fulvestrant (ICI 182,780) Inhibits the Anti-Inflammatory Effect of Glucocorticoids

Cuzzocrea, S., Bruscoli, S., Crisafulli, C., Mazzon, E., Agostini, M., Muià, C., Esposito, E., Virgilio, R. D., Meli, R., Vegeto, E., et al. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.029629 · Cited by 28

The potential risk factors leading to peptic ulcer formation in autoimmune disease patients receiving corticosteroid treatment

Luo, J., Chang, F. ‐., Lin, H., Lu, R. H., Lu, C., Chen, C.-W., & Lee, S. (2002) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2002.01279.x · Cited by 28

Repression of p65 Transcriptional Activation by the Glucocorticoid Receptor in the Absence of Receptor-Coactivator Interactions

Wu, J., Yu, L., Dietz, J. D., & Lala, D. S. (2003) · Molecular Endocrinology · doi:10.1210/me.2002-0373 · Cited by 27

Cytokines and HPA Axis Regulation

Silverman, M. N., Pearce, B. D., & Miller, A. H. (2003) · Neurobiological foundation of aberrant behaviors · doi:10.1007/978-1-4615-0323-1_5 · Cited by 29

Identification of Glucocorticoid Receptor Domains Involved in Transrepression of Transforming Growth Factor-β Action

Li, G., Wang, S., & GELEHRTER, T. D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305350200 · Cited by 26

Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner

Weikum, E. R., Okafor, C. D., D’Agostino, E. H., Colucci, J. K., & Ortlund, E. A. (2017) · Molecular Pharmacology · doi:10.1124/mol.117.108506 · Cited by 25

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Desmet, S. J., Bougarne, N., Moortel, L. V., Cauwer, L. D., Thommis, J., Vuylsteke, M., Ratman, D., Houtman, R., Tavernier, J. H., & Bosscher, K. D. (2017) · Scientific Reports · doi:10.1038/s41598-017-07941-y · Cited by 25

Functional Analysis of Three Genetic Polymorphisms in the Glucocorticoid Receptor Gene

Koyano, S., Saito, Y., Nagano, M., Maekawa, K., Kikuchi, Y., Murayama, N., Fujino, T., Ozawa, S., Nakajima, T., Matsumoto, K., et al. (2003) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.054155 · Cited by 25

Anti-inflammatory drugs, eicosanoids and the annexin A1/FPR2 anti-inflammatory system

Yazid, S., Norling, L. V., & Flower, R. (2011) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2011.11.005 · Cited by 24

Role of Steroid Receptor Coactivators in Glucocorticoid and Transforming Growth Factor β Regulation of Plasminogen Activator Inhibitor Gene Expression

Li, G., Heaton, J. H., & GELEHRTER, T. D. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0145 · Cited by 24

A role for glucocorticoids in the thymus?

Jondal, M., Pazirandeh, A., & Okret, S. (2001) · Trends in Immunology · doi:10.1016/s1471-4906(01)01871-3 · Cited by 24

Dietary tryptophan intervention counteracts stress-induced transcriptional changes in a teleost fish HPI axis during inflammation

Peixoto, D., Carvalho, I., Machado, M., Aragão, C., Costas, B., & Azeredo, R. (2024) · Scientific Reports · doi:10.1038/s41598-024-57761-0 · Cited by 23

The functional role of nuclear factor kappa-κB1 −94 ins/del ATTG promotor gene polymorphism in Behçet’s disease: an exploratory study

Yalçın, B., Atakan, N., & Allı, N. (2008) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.2008.02786.x · Cited by 23

Glucocorticoids increase C/EBPβ activity in the lung epithelium via phosphorylation

Berg, T., Didon, L., Barton, J. L., Andersson, O., & Nord, M. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.06.146 · Cited by 23

Novel Genetic Polymorphisms in the NR3C1 (Glucocorticoid receptor) Gene in a Japanese Population

Koyano, S., Saito, Y., Sai, K., Kurose, K., Ozawa, S., Nakajima, T., Matsumoto, K., Saito, H., Shirao, K., Yoshida, T., et al. (2005) · Drug Metabolism and Pharmacokinetics · doi:10.2133/dmpk.20.79 · Cited by 20

The Gateway Reflex, a Novel Neuro-Immune Interaction for the Regulation of Regional Vessels

Tanaka, Y., Arima, Y., Kamimura, D., & Murakami, M. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01321 · Cited by 20

Integrated analysis of microRNA and mRNA expression profiles highlights aldehyde-induced inflammatory responses in cells relevant for lung toxicity

Song, M., Lee, H.-S., & Ryu, J. (2015) · Toxicology · doi:10.1016/j.tox.2015.06.007 · Cited by 20

Whole blood transcriptional variations between responders and non‐responders in asthma patients receiving omalizumab

Upchurch, K., Wiest, M. J., Cardenas, J., Skinner, J. A., Nattami, D., Lanier, B. Q., Millard, M., Joo, H., Turner, J., & Oh, S. (2020) · Clinical & Experimental Allergy · doi:10.1111/cea.13671 · Cited by 19

Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores

Betageri, R., Gilmore, T., Kuzmich, D., Kirrane, T. M., Bentzien, J., Wiedenmayer, D., Bekkali, Y., Regan, J. R., Berry, A. K., Latli, B., et al. (2011) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2011.09.018 · Cited by 19

Targeting Nuclear Hormone Receptors: PPARαAgonists as Potential Disease-Modifying Drugs for Rheumatoid Arthritis

Shirinsky, I. V., & Shirinsky, V. S. (2011) · International Journal of Rheumatology · doi:10.1155/2011/937843 · Cited by 18

Can corticosteroids reduce the mortality of patients with severe sepsis? A systematic review and meta-analysis

Ni, Y.-N., Liu, Y.-M., Wang, Y., Liang, B., & Liang, Z. (2018) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2018.11.040 · Cited by 20

Transcriptome Profile Analysis of Saturated Aliphatic Aldehydes Reveals Carbon Number-Specific Molecules Involved in Pulmonary Toxicity

Song, M., Choi, H., Lee, H.-S., & Ryu, J. (2014) · Chemical Research in Toxicology · doi:10.1021/tx500171r · Cited by 18

Inhibition of signal transduction pathways involved in inflammation

Haegeman, G. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00000503a · Cited by 18

Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid‐binding globulin

Meyer, E. J., Torpy, D. J., Chernykh, A., Thaysen‐Andersen, M., Nenke, M. A., Lewis, J. G., Rajapaksha, H., Rankin, W. A., & Polyak, S. W. (2020) · Protein Science · doi:10.1002/pro.3982 · Cited by 17

Glucocorticoids inhibit the innate immune system of human corneal fibroblast through their suppression of toll-like receptors.

Jin, X., Qin, Q., Tu, L., & Qu, J. (2009) · PubMed Central · Cited by 16

Immunosuppression in uveitis

Djalilian, A. R., & Nussenblatt, R. B. (2002) · Ophthalmology Clinics of North America · doi:10.1016/s0896-1549(02)00036-6 · Cited by 16

Induction and Repression of NF-κB-Driven Inflammatory Genes

Berghe, W. V., Bosscher, K. D., Vermeulen, L., Wilde, G., & Haegeman, G. (2002) · Springer eBooks · doi:10.1007/978-3-662-04660-9_14 · Cited by 16

Anti-Inflammatory Actions of Glucocorticoids

Wikström, A., Gustafsson, J.-Α., & Okret, S. (2003) · Encyclopedia of Hormones · doi:10.1016/b0-12-341103-3/00020-6 · Cited by 16

Corticosteroid Use in Small Animal Neurology

Jeffery, N. D. (2014) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2014.07.004 · Cited by 14

Tristetraprolin is involved in the glucocorticoid-mediated interleukin 8 repression

Shi, J., Li, J., Hu, R., Shi, Y. P., Su, X., Guo, X., & Li, X.-M. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.07.031 · Cited by 14

Hydrocortisone-induced anti-inflammatory effects in immature human enterocytes depend on the timing of exposure

Rautava, S., Walker, W. A., & Lu, L. (2016) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00457.2015 · Cited by 14

Serum concentrations, pharmacokinetic/pharmacodynamic modeling, and effects of dexamethasone on inflammatory mediators following intravenous and oral administration to exercised horses

Knych, H. K. D., Weiner, D., Arthur, R. M., Baden, R. W., McKemie, D. S., & Kass, P. H. (2020) · Drug Testing and Analysis · doi:10.1002/dta.2862 · Cited by 14

A novel aspect of the anti-inflammatory actions of glucocorticoids: inhibition of proximal steps of signaling cascades in lymphocytes

Laethem, F. V., Baus, E., Andris, F., Urbain, J., & Léo, O. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000799 · Cited by 14

Reduced Expression of Membrane Complement Regulatory Protein CD59 on Leukocytes following Lung Transplantation

Michielsen, L. A., Budding, K., Drop, D. A. C. A. D., van de Graaf, E. A., Kardol‐Hoefnagel, T., Verhaar, M. C., van Zuilen, A. D., & Otten, H. G. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.02008 · Cited by 13

Synthesis and Molecular Modeling Studies of Anti‐inflammatory Active 1H‐Pyrrolizine‐5‐carboxamides

Barsoum, F. F. (2010) · Archiv der Pharmazie · doi:10.1002/ardp.201000166 · Cited by 13

Green Tea Polyphenols as Potent Enhancers of Glucocorticoid-Induced Mouse Mammary Tumor Virus Gene Expression

Abe, I., Umehara, K., Morita, R., Nemoto, K., Degawa, M., & Noguchi, H. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4325 · Cited by 13

Experience with experimental biological treatment and local gene therapy in Sjögren's syndrome: implications for exocrine pathogenesis and treatment

Lodde, B. M., Baum, B. J., Tak, P. P., & Illei, G. (2006) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.052761 · Cited by 13

Molecular Mechanisms of Glucocorticoid Action

Bloom, J. W. (2001) · Lung biology in health and disease · doi:10.1201/b14023-9 · Cited by 13

NFκB and AP-1 DNA binding activity in patients with multiple sclerosis

Flores, N., Durán, C., Quilez, M. R. B., Puerta, C., Dorado, B., Garcı́a-Merino, A., & Ballester, S. (2003) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(02)00440-x · Cited by 13

Evolving paradigm of treatment for autoimmune hepatitis

Czaja, A. J. (2017) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2017.1319764 · Cited by 12

Repeated stimulation of the HPA axis alters white blood cell count without increasing oxidative stress or inflammatory cytokines in fasting elephant seal pups

Ensminger, D. C., Crocker, D. E., Lam, E. K., Allen, K. N., & Vázquez‐Medina, J. P. (2021) · Journal of Experimental Biology · doi:10.1242/jeb.243198 · Cited by 12

Nefecon (Targeted-Release Formulation-Budesonide) for the Treatment of IgA Nephropathy

Vecchio, L. D., Rimoldi, C., & Pozzi, C. (2021) · Future Rare Diseases · doi:10.2217/frd-2021-0013 · Cited by 12

Effect of leukoreduction on inflammation in critically ill dogs receiving red blood cell transfusions: A randomized blinded controlled clinical trial

Claus, M. A., Poh, D., Smart, L., Purcell, S. L., Boyd, C. J., & Sharp, C. R. (2022) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.16487 · Cited by 12

cAMP signaling can antagonize potent glucocorticoid post-transcriptional inhibition of stanniocalcin gene expression

Groves, T., Wagner, G. F., & DiMattia, G. E. (2001) · Journal of Endocrinology · doi:10.1677/joe.0.1710499 · Cited by 12

Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β

O’Neil, J. D., Bolimowska, O. O., Clayton, S. A., Tang, T., Daley, K. K., Reyna, S. J. L., Warner, J., Martin, C., Mahida, R. Y., Hardy, R., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1190261 · Cited by 14

Dexamethasone restrains ongoing expression of interleukin-23p19 in peripheral blood-derived human macrophages

Palma, L., Sfara, C., Antonelli, A., & Magnani, M. (2011) · BMC Pharmacology · doi:10.1186/1471-2210-11-8 · Cited by 11

Chromatin organization as an indicator of glucocorticoid induced natural killer cell dysfunction

Misale, M. S., Janusek, L. W., Tell, D., & Mathews, H. L. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.09.004 · Cited by 11

Glucocorticoids: Inflammation and Immunity

Petrillo, M. G., Bortner, C. D., & Cidlowski, J. A. (2016) · Springer eBooks · doi:10.1007/978-3-319-45950-9_3 · Cited by 10

Antibody response of channel catfish after channel catfish virus infection and following dexamethasone treatment

Arnizaut, A. B., & Hanson, L. (2011) · Diseases of Aquatic Organisms · doi:10.3354/dao02348 · Cited by 10

Efficacy and safety of corticosteroid therapy in patients with cardiac arrest: A meta-analysis of randomized controlled trials

Zhou, F.-W., Liu, C., Li, D., Zhang, Y., & Zhou, F. (2023) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2023.10.031 · Cited by 9

Mechanism of Glucocorticoid-Induced Osteoporosis: An Update

Shi, X., Chutkan, N. B., Mark, W., & Carlos, M. (2012) · InTech eBooks · doi:10.5772/53978 · Cited by 9

Possible role of corticosterone on behavioral, physiological, and immune responses in chicks

Tachibana, T., Okuyama, H., Takahashi, M., Khan, S., Makino, R., & Cline, M. A. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114357 · Cited by 9

Differential regulation of sensitizer-induced inflammation and immunity by acute restraint stress in allergic contact dermatitis

Flint, M. S., Depree, K. M., Rich, B. A., & Tinkle, S. S. (2003) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(03)00163-2 · Cited by 9

Effective topical agents and emerging perspectives in the treatment of psoriasis

Chiricozzi, A., & Chimenti, S. (2012) · Expert Review of Dermatology · doi:10.1586/edm.12.18 · Cited by 9

Hsp90 regulation affects the treatment of glucocorticoid for pancreatitis-induced lung injury

Zhao, Y., Xiong, R., Chen, X., Li, P., Ning, Y., Yang, N., Peng, Y., Jiang, Y.-L., & Zhou, Y. (2017) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-017-3166-y · Cited by 9

The Hypothalamic‐Pituitary‐Adrenal Axis and Low‐Dose Glucocorticoids in the Treatment of Septic Shock

Williamson, D. R., & Lapointe, M. (2003) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.23.4.514.32123 · Cited by 9

Cortisol Dose-Dependently Impairs Migration and Tube-like Formation in a Trophoblast Cell Line and Modulates Inflammatory and Angiogenic Genes

Húngaro, T. G. R., Gregnani, M. F., Alves-Silva, T., Herse, F., Alenina, N. V., Bäder, M., & Araújo, R. C. (2021) · Biomedicines · doi:10.3390/biomedicines9080980 · Cited by 8

Effects of rhubarb on the expression of glucocorticoids receptor and regulation of cellular immunity in burn-induced septic rats

Liu, J., Li, G., Chen, Y., Zhang, L.-D., Wang, T., Wen, Z., Wang, L., & Chen, D. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000201 · Cited by 8

Administering dexamethasone to prepartum sows: Effects on sow and piglet performance

Ward, S. A., Kirkwood, R. N., & Plush, K. J. (2020) · Livestock Science · doi:10.1016/j.livsci.2020.104171 · Cited by 8

Management of the Acutely Neurologic Patient

Morresey, P. R. (2006) · Clinical techniques in equine practice · doi:10.1053/j.ctep.2006.03.004 · Cited by 7

Immunotherapy

Felippe, M. J. B. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-0891-8.00066-x · Cited by 7

Interactions négatives entre récepteurs nucléaires et facteurs transcriptionnels

Vlaeminck‐Guillem, V., Laudet, V., & Duterque‐Coquillaud, M. (2003) · médecine/sciences · doi:10.1051/medsci/200319111121 · Cited by 8

Glucocorticoid-Inducible Genes That Regulate T-Cell Function

Mittelstadt, P. R., Galon, J., Franchimont, D. P., O’Shea, J. J., & Ashwell, J. D. (2002) · Springer eBooks · doi:10.1007/978-3-662-04660-9_18 · Cited by 6

Pleiotropic effects of PPAR-α – from benchside to bedside

Shirinsky, I. V., & Shirinsky, V. S. (2021) · Medical Immunology (Russia) · doi:10.15789/1563-0625-peo-2222 · Cited by 6

Anti-Inflammatory Effects of Levalbuterol-Induced 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Airway Epithelial Cells

Randall, M. J., Kostin, S. F., Burgess, E. J., Hoyt, L. R., Ather, J. L., Lundblad, L. K. A., & Poynter, M. E. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00236 · Cited by 6

Differential Effects of Low- and High-dose Glucocorticoids on the Innate Immunity of Corneal Epithelium in Vitro

Xie, X., Yan, X., Lin, Z., & Jin, X. (2011) · Ocular Immunology and Inflammation · doi:10.3109/09273948.2011.569110 · Cited by 6

The Molecular and Cellular Mechanisms Responsible for the Anti-inflammatory and Immunosuppressive Effects of Glucocorticoids

Nocentini, G., Migliorati, G., & Riccardi, C. (2015) · Springer eBooks · doi:10.1007/978-3-319-16056-6_4 · Cited by 6

A dopamine mechanism is implied in the acquisition and expression of amphetamine and stress-induced effects observed in the lymphocyte subpopulations

Assis, M. A., Pacchioni, A. M., Collino, C., Paz, M. C., Sotomayor, C. E., Basso, A. M., & Cancela, L. M. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.02.007 · Cited by 6

COMPARISION OF THE APOPTOTIC EFFECTS ON LYMPHOBLASTS AND ON INCREASE OF MYELOID LINEAGE CELLS OF A SHORT-TIME, HIGH-DOSE METHYLPREDNISOLONE AND THE CONVENTIONAL-DOSE PREDNISOLONE TREATMENTS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Erduran, E., Tekelioğlu, Y., Karakaş, T., Gedik, Y., & Mert, F. M. (2006) · Pediatric Hematology and Oncology · doi:10.1080/08880010600857053 · Cited by 6

Stress, Peer Affiliation, and Transforming Growth Factor-β1 in Differentially Reared Primates

Smith, E. L., Batuman, O., Coplan, J. D., & Rosenblum, L. A. (2001) · CNS Spectrums · doi:10.1017/s109285290000211x · Cited by 6

Immunologic targets for currently available immunosuppressive agents: What is the optimal approach for children?

Sho, M., Samsonov, D. V., & Briscoe, D. M. (2001) · Seminars in Nephrology · doi:10.1053/snep.2001.24946 · Cited by 6

Glucocorticoid-induced diabetes mellitus: mechanisms, risk factors, and clinical pathways with insights from autoimmune rheumatic diseases

Soura, M., Bakiri, A., Fragoulis, G., & Vassilakis, K. D. (2026) · Rheumatology International · doi:10.1007/s00296-026-06099-z · Cited by 5

[Molecular mechanisms of action of some immunosuppressive drugs].

Liberman, A. C., Druker, J., Refojo, D., & ARZT, E. S. (2008) · PubMed · Cited by 7

Experimental Evidence that the Maize Activator (Ac) Transposase Can Act on a non-Transposable Element Promoter to Repress Reporter Gene Expression in Transient Plant Assays

MacRae, A. F. (2002) · Genetica · doi:10.1023/a:1020636901790 · Cited by 5

Molecular Mechanisms of Glucocorticoids Action: From Basic Research to Clinical Implications

Liberman, A. C., Castro, C. N., Antunica-Noguerol, M., Tabarrozzi, A. E. B., Druker, J., Perone, M. J., & ARZT, E. S. (2010) · Current Immunology Reviews · doi:10.2174/1573395511006040371 · Cited by 4

Heat Shock Protein 90 and Reproduction in Female Animals: Ovary, Oocyte and Early Embryo

Yang, Y., Chen, L., & Yang, C. (2019) · Heat shock proteins · doi:10.1007/978-3-030-23158-3_23 · Cited by 4

Glucocorticosteroids

Adcock, I. M., & Chung, K. F. (2014) · Elsevier eBooks · doi:10.1016/b978-0-323-08593-9.00100-5 · Cited by 4

Repression of transcription factor NF-[kappa]B by glucocorticoids : a molecular mechanism for their anti-inflammatory and immuno-modulatory effects

Lidén, J. (2000) · Figshare

Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids

Almawi, W., & Melemedjian, O. (2002) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0280069 · Cited by 242

The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression

De Bosscher, K., Vanden Berghe, W., & Haegeman, G. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0006 · Cited by 898

Nuclear Factor-κ B Repression in Antiinflammation and Immunosuppression by Glucocorticoids

van der Burg, B., Lidén, J., Okret, S., Delaunay, F., Wissink, S., van der Saag, P. T., & Gustafsson, J.-Α. (1997) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(97)00006-4 · Cited by 58

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

Auphan, N., DiDonato, J. A., Rosette, C., Helmberg, A., & Karin, M. (1995) · Science · doi:10.1126/science.270.5234.286 · Cited by 2,390