The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
New insights into the regulation and function of brain estrogen synthase (aromatase)
Open accessAbstract
In the brain, conversion of androgens into estrogens by the enzyme aromatase (estrogen synthase) is a key mechanism by which testosterone regulates many physiological and behavioral processes, including the activation of male sexual behavior, brain sexual differentiation and negative feedback effects of steroid hormones on gonadotropin secretion. Studies on the distribution and regulation of brain aromatase have led to a new perspective on the control and function of this enzyme. A growing body of evidence indicates that the estrogen regulation of aromatase is, at least in part, trans-synaptic. Afferent catecholamine pathways appear to regulate aromatase activity in some brain areas and thereby provide a way for environmental cues to modulate this enzyme. The localization of aromatase in pre-synaptic boutons suggests possible roles for estrogens at the synapse.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cloning of a novel receptor expressed in rat prostate and ovary.
Kuiper, G. G., Enmark, E., Pelto-Huikko, M., Nilsson, S., & Gustafsson, J. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.5925 · Cited by 4,788
Kuiper, G. G. J. M., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S., & Gustafsson, J.-A. (1997) · Endocrinology · doi:10.1210/endo.138.3.4979 · Cited by 4,442
Comparative distribution of estrogen receptor-? and -? mRNA in the rat central nervous system
Shughrue, P. J., Lane, M. V., & Merchenthaler, I. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19971201)388:4<507::aid-cne1>3.0.co;2-6 · Cited by 2,259
Molecular and Cellular Basis of Addiction
Nestler, E. J., & Aghajanian, G. K. (1997) · Science · doi:10.1126/science.278.5335.58 · Cited by 1,313
The Formation of Estrogens by Central Neuroendocrine Tissues
NAFTOLIN, F., RYAN, K. J., DAVIES, I. J., REDDY, V. V., FLORES, F., PETRO, Z., KUHN, M., WHITE, R. J., TAKAOKA, Y., & WOLIN, L. (1975) · Proceedings of the 1974 Laurentian Hormone Conference · doi:10.1016/b978-0-12-571131-9.50012-8 · Cited by 793
Recent Advances in the Molecular Biology of Dopamine Receptors
Gingrich, J. A., & Caron, M. G. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.001503 · Cited by 779
Advances in Comparative and Environmental Physiology: Volume 7
Houlihan, D. F., Livingstone, D. R., & Lee, R. F. (1991) · Advances in Comparative and Environmental Physiology · doi:10.1007/978-3-642-75897-3 · Cited by 738
Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor
Mermelstein, P., Becker, J., & Surmeier, D. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00595.1996 · Cited by 632
A review of brain aromatase cytochrome P450
LEPHART, E. (1996) · Brain Research Reviews · doi:10.1016/0165-0173(96)00002-1 · Cited by 505
Neural Gonadal Steroid Actions
McEwen, B. S. (1981) · Science · doi:10.1126/science.6259728 · Cited by 438
Cited by
Garcia-Segura, L. M., Azcoitia, I., & DonCarlos, L. L. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00025-3 · Cited by 938
Estradiol and the Developing Brain
McCARTHY, M. M. (2008) · Physiological Reviews · doi:10.1152/physrev.00010.2007 · Cited by 885
The genetics of sex differences in brain and behavior
Ngun, T. C., Ghahramani, N., Sánchez, F. J., Bocklandt, S., & Vilain, E. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.10.001 · Cited by 440
Hormones, developmental plasticity and adaptation
Dufty, A. (2002) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(02)02498-9 · Cited by 382
Forlano, P. M., Deitcher, D. L., Myers, D. A., & Bass, A. H. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-22-08943.2001 · Cited by 304
Metadata
- Authors
- Balthazart, J., & Ball, G. F.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 1998-06
- Volume
- 21
- Issue
- 6
- Pages
- 243-249
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W1975909673
- Cited by
- 276
- References
- 74
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: New insights into the regulation and function of brain estrogen synthase (aromatase). https://app.cochat.ai/papers/10.1016/s0166-2236(97)01221-6
- The paper
- Balthazart, J., & Ball, G. F. (1998). New insights into the regulation and function of brain estrogen synthase (aromatase). Trends in Neurosciences. https://doi.org/10.1016/s0166-2236(97)01221-6
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
