CoChat
Sign Up
Cited by 145Growth Hormone and Insulin-like Growth FactorsHormonal and reproductive studiesHeart Failure Treatment and Management

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Hormonal profile in patients with congestive heart failure

Kontoleon, Panagiotis E, Anastasiou-Nana, Maria I, Papapetrou, Petros D, Alexopoulos, George, Ktenas, Vasiliki, Rapti, Ageliki C, Tsagalou, Eleftheria P, Nanas, John N·2003·International Journal of Cardiology
DOI 10.1016/s0167-5273(02)00212-7
Open this paper in CoChat — free account

Abstract

Background Recent progress has been made in the understanding of the cellular and molecular mechanisms of growth hormone action and of its effects on cardiac tissue. The aim of this study was to measure growth hormone concentrations, along with various other hormones, in patients with stable chronic congestive heart failure due to idiopathic dilated cardiomyopathy.Methods The study included 23 ambulatory men, 51.2+/-9.3 years of age, on standard medical therapy for heart failure due to idiopathic dilated cardiomyopathy. All patients underwent clinical and laboratory evaluations, including echocardiogram, radionuclide ventriculography, right heart catheterization, coronary angiography, and right ventricular endomyocardial biopsy. Serum or plasma concentrations of growth, thyroid, sex and adrenal hormones were measured in all patients and compared with those found in 20 age-matched healthy men.Results Growth hormone, insulin-like growth factor I, and free testosterone values in patients with idiopathic dilated cardiomyopathy and heart failure were 0.37+/-0.2 ng/ml, 123.7+/-50 ng/ml and 48.6+/-23.8 pmol/l, respectively, versus 0.5+/-0.4 ng/ml (P<0.01), 236.3+/-66.4 ng/ml (P<0.001) and 105+/-17 pmol/l (P<0.01), respectively, in the healthy age-matched individuals. All other hormone concentrations were comparable in both groups.Conclusions Chronic heart failure due to idiopathic dilated cardiomyopathy is associated with a significant decrease in growth hormone, insulin-like growth factor I, and testosterone concentrations, probably due to chronic disease.

Overview

Integrity signals

Registry

Crossref · 10.1016/s0167-5273(02)00212-7

Cites

42 of 42 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 42 references

Cited by

Sorted by citations

Related

See all

Metadata

Authors
Kontoleon, P. E., Anastasiou-Nana, M. I., Papapetrou, P. D., Alexopoulos, G., Ktenas, V., Rapti, A. C., Tsagalou, E. P., & Nanas, J. N.
Affiliations
  • Alexandra Hospital (GR)
  • National and Kapodistrian University of Athens (GR)
Venue
International Journal of Cardiology
Publisher
Elsevier BV
Published
2003-02
Volume
87
Issue
2-3
Pages
179-183
ISSN
0167-5273 (ISSN-L)
DOI
10.1016/s0167-5273(02)00212-7
OpenAlex
W2066253688
Cited by
145
References
42
Citations by year
2026: 1 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 7 · 2021: 6 · 2020: 5 · 2019: 7 · 2018: 4 · 2017: 8 · 2016: 4 · 2015: 5 · 2014: 10 · 2013: 9 · 2012: 7
FWCI
4.68
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • International Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Keywords
congestive heart failure, idiopathic dilated cardiomyopathy, growth hormone, insulin-like growth factor I, free testosterone, hormonal profile, chronic disease, sex hormones, thyroid hormones, adrenal hormones
MeSH terms
Adult, Aged, Analysis of Variance, Cardiomyopathy, Dilated, Heart Failure, Humans, Insulin-Like Growth Factor I, Male, Middle Aged, Probability, Prognosis, Radioimmunoassay, Reference Values, Sensitivity and Specificity, Severity of Illness Index, Growth Hormone, Testosterone, Cohort Studies, Biomarkers, Case-Control Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review